Prionailurus bengalensis (leopard cat): 122492079
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Entry
122492079 CDS
T07574
Symbol
TGFBR2
Name
(RefSeq) TGF-beta receptor type-2 isoform X1
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
pbg
Prionailurus bengalensis (leopard cat)
Pathway
pbg04010
MAPK signaling pathway
pbg04060
Cytokine-cytokine receptor interaction
pbg04068
FoxO signaling pathway
pbg04144
Endocytosis
pbg04218
Cellular senescence
pbg04350
TGF-beta signaling pathway
pbg04380
Osteoclast differentiation
pbg04390
Hippo signaling pathway
pbg04520
Adherens junction
pbg04659
Th17 cell differentiation
pbg04926
Relaxin signaling pathway
pbg04933
AGE-RAGE signaling pathway in diabetic complications
pbg05142
Chagas disease
pbg05161
Hepatitis B
pbg05166
Human T-cell leukemia virus 1 infection
pbg05200
Pathways in cancer
pbg05202
Transcriptional misregulation in cancer
pbg05210
Colorectal cancer
pbg05212
Pancreatic cancer
pbg05220
Chronic myeloid leukemia
pbg05225
Hepatocellular carcinoma
pbg05226
Gastric cancer
pbg05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pbg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
122492079 (TGFBR2)
04350 TGF-beta signaling pathway
122492079 (TGFBR2)
04390 Hippo signaling pathway
122492079 (TGFBR2)
04068 FoxO signaling pathway
122492079 (TGFBR2)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
122492079 (TGFBR2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
122492079 (TGFBR2)
09143 Cell growth and death
04218 Cellular senescence
122492079 (TGFBR2)
09144 Cellular community - eukaryotes
04520 Adherens junction
122492079 (TGFBR2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
122492079 (TGFBR2)
09152 Endocrine system
04926 Relaxin signaling pathway
122492079 (TGFBR2)
09158 Development and regeneration
04380 Osteoclast differentiation
122492079 (TGFBR2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
122492079 (TGFBR2)
05202 Transcriptional misregulation in cancer
122492079 (TGFBR2)
09162 Cancer: specific types
05210 Colorectal cancer
122492079 (TGFBR2)
05212 Pancreatic cancer
122492079 (TGFBR2)
05225 Hepatocellular carcinoma
122492079 (TGFBR2)
05226 Gastric cancer
122492079 (TGFBR2)
05220 Chronic myeloid leukemia
122492079 (TGFBR2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
122492079 (TGFBR2)
05161 Hepatitis B
122492079 (TGFBR2)
09174 Infectious disease: parasitic
05142 Chagas disease
122492079 (TGFBR2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
122492079 (TGFBR2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
122492079 (TGFBR2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pbg01001
]
122492079 (TGFBR2)
Enzymes [BR:
pbg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
122492079 (TGFBR2)
Protein kinases [BR:
pbg01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
122492079 (TGFBR2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
122492079
NCBI-ProteinID:
XP_043451534
LinkDB
All DBs
Position
C2:147479513..147571003
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AA seq
604 aa
AA seq
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MGRGLLRGLWPLHIVLWTRIASTIPPHVLKSVNNGMMVTDNNGIIKFPQLCKFCDVRSST
CDSQKSCLSNCSITSICERPHEVCLAVWRKNDENITLETLCHDPKVTYHGIALEDSASPK
CIMKEKKVLGETFFMCSCSTDECNDYIIFSEDLQFMLSRESCGWHPVPVFKRNASTISPL
ESSLLKTIEYATNNPDLLLVIFQVTGVSLLPPLGIAIAVIIIFYCYRVHRQQKLSPSWDT
SKPRKLMEFSEHLAIILEDDRSDISSTCANNINHNTELLPIELDTLVGKGRFAEVYKAKL
KQNTSEQFETVAVKIFPYEEYASWKTEKDIFSDINLKHENILQFLTAEERKTELGKQYWL
ITAFHAKGNLQEYLTRHVISWEDLRTLGSSLARGIAHLHSDHTLCGRPKMPIVHRDLKSS
NILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVGTARYMAPEVLESRMNLENVESFK
QTDVYSMALVLWEMTSRCNAVGEVKEYEPPFGSKVREHPCVESMKDNVLRDRGRPEIPSS
WLNHQGIQMVCETLTECWDHDPEARLTAQCVAERFSELQHLDRLSGRSCSEEKIPEDGSL
NTTK
NT seq
1815 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctccggggcctgtggccgctgcacatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcacgttctgaagtccgttaacaatggcatgatggtcaccgac
aacaatggtatcatcaagtttccgcaattgtgcaaattttgtgatgtgagatcttccacc
tgtgacagccagaaatcctgcctgagcaactgcagcatcacgtctatctgcgagaggcca
catgaagtctgtctggccgtctggagaaagaacgatgagaacataaccctagagacgctt
tgccatgaccccaaggttacctaccatggcattgctcttgaagactctgcttctcccaag
tgtattatgaaggaaaaaaaggtgttgggcgagactttctttatgtgttcctgtagcacc
gatgaatgcaatgactacatcatcttctcagaagatctccagttcatgctcagtagagag
agctgtggttggcatcctgttcctgtttttaaaagaaatgcatctaccatttccccgtta
gaatcaagtttgctgaagaccattgaatacgccaccaacaaccctgacctgttgttagtc
atattccaagtgacaggcgtcagcctcctgccccccctggggatcgccatagccgtcatc
atcatcttctactgttaccgtgttcaccggcagcagaagctgagcccatcctgggatacc
agcaagccacgaaagctcatggagttcagcgagcaccttgccatcattctggaagacgac
cgctctgacatcagctctacctgcgccaacaacatcaaccacaacacagagctgctgccc
attgagctggacaccctggtggggaaaggccgcttcgccgaggtctacaaggccaagctg
aagcagaacacttctgaacagttcgagaccgtggcggtcaagatcttcccttacgaggag
tacgcctcctggaagacggagaaggacattttctcagacatcaacctgaagcacgagaac
atactgcagttcctgacagccgaggagcgcaagacggagctggggaagcagtactggctg
atcacggccttccacgccaagggcaacctgcaggagtacctgacgcggcacgtcatcagc
tgggaggacctgcgcacgctgggcagctccctcgcccggggcattgcccacctgcacagc
gaccacaccctgtgcgggaggcccaagatgcccatcgtgcacagggacctcaagagctcc
aatatcctcgtcaagaacgatctgacctgctgcctgtgtgactttgggctttccctgcgt
ctggacccgaccctgtctgtggatgacctggccaacagcgggcaggtgggaactgcaaga
tacatggctccagaagtcctagagtccaggatgaatttggagaatgttgagtcctttaag
cagacggatgtctactccatggctctggtcctctgggaaatgacatctcgctgtaatgcg
gtaggagaggtgaaagaatacgagcctccatttggttccaaggtgcgggagcatccctgt
gttgagagcatgaaggacaatgtgctgagagaccgaggccgaccagaaattcccagctcc
tggctcaaccaccagggcatccagatggtgtgcgagactctgaccgagtgctgggaccat
gacccggaggcccggctcacggcccagtgcgtggcagagcgcttcagtgaactgcagcac
ctggacaggctctcggggaggagctgctccgaggagaagattcccgaagatggctcgttg
aacactaccaaatag
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