KEGG   Physeter macrocephalus (sperm whale): 102994468
Entry
102994468         CDS       T06011                                 
Symbol
WNK1
Name
(RefSeq) serine/threonine-protein kinase WNK1 isoform X22
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
pcad  Physeter macrocephalus (sperm whale)
Pathway
pcad04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:pcad00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    102994468 (WNK1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcad01001]
    102994468 (WNK1)
   01009 Protein phosphatases and associated proteins [BR:pcad01009]
    102994468 (WNK1)
Enzymes [BR:pcad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     102994468 (WNK1)
Protein kinases [BR:pcad01001]
 Serine/threonine kinases: Other
  Wnk family
   102994468 (WNK1)
Protein phosphatases and associated proteins [BR:pcad01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     102994468 (WNK1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C Pkinase_fungal
Other DBs
NCBI-GeneID: 102994468
NCBI-ProteinID: XP_007117149
Ensembl: ENSPCTG00005009375
UniProt: A0A2Y9FA30
LinkDB
Position
6:complement(54782218..54924748)
AA seq 2366 aa
MSGGAADQQSSAPGSLFLSPPAPAPKNGSSSDSSVGEKLGAAAADAGAGRTEEYRRRRHT
MDKDSRGAVATTTTEHRFFRRSVICDSNATALELPGLPLPLPQTSAAAVVPQRSPPEPQR
EETLTPAAAHVAQQPPAAAAAPGEPVAAVPAAASAPGSAGRDRQVAQPGHAGSKEEPPSS
RSGSGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGLDT
ETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVLVT
ELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITGPT
GSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSEYP
YSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFFQE
ETGVRVELAEEDDGEKIAIKLWLRIEDSKKLKGKYKDNEAIEFSFDLERDVPEDVAQEMV
DSGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEESSLKQQGEQQSSASQ
AGAQQPPSTCTGGPAASTTSASVSTQVEPEEPEADQHQQLQHQPPGVSVLSDGTVDSGQG
SSVFTESRVSSQQTVSYGSQHEQAHSTGTLPGHTAPVVQAQAQPHGVYPPSSMAQGQSQG
QQSSSSLTGVSSSQPIQHSQQQQGVQQTAPSQQTAQYSLPQTSASSEAMTAQPASQPQPP
QSLSHVSAGKQLPVSQPVPTIQGEPHIPVATQPSVVPVHSGAHFLPAGQPLPPSSLPQYP
VSQIPSASQPAFSPLPVTMAAGVNQPLLTLASSAPAAAVPGGPPLVPNLPTLLQPVTQLP
NQAHPQLLQPAVQSMGIAANLGQTAEAPLPSGDVLYQGFPPRPPPQHPGDSKLAPSSSVP
SVCVPSTVLSPPAPAEALAAPGYFPTVVQPYVESSLLVPVGSIGGQVQVSQPAVSLAQAP
TTSSQQAALESTQGVSQVAPPEPVPVAQPQPTQPATLVSSVDSAHSDVASGMSDGNENVP
SSSGRHEGRTTKRHYRKSVRSRSRHEKTSRPKLRILNVSNKGDRVVECQLETHNRKMVTF
KFDLDGDNPEEIATIMVNNDFILAMEREAFVEQVRDIIEKADEMLSEDVSVEPEGDQGLE
SLQGKDDYGFAGSQKLEGEFKQPIPASSMPQQIGLPTSSLTQVVHSAGRRFIVSPVPESR
LRESKIFSEVSDTVAAPTSAGAGMSLSHSASSLSLQQAFSELRRAHTAEGPSTAPANFRP
TGPAFPAVPPSVISPAGAPATAAAVPSASTPAMGCPPSDPSTSAVQSEVAVPAEKGIAGV
ATCTGIIPSSGLPAPPASESPILSSVVSSITAPAVVSVSATSQSVQAPTPGSVVSSTGTF
PPVPVSVTAASAASSAAAPGAKPSPVSSQQVVGSMAGAATLTSVSATAPVPSLAAQPSLP
PSSSTSALTRAETVVVSAHALDKISHGSLTGLALSLPASPSSPSLGAGVSSAVAQPGVAH
PLVIPSAVASTPALSQAGPPCTPFLPQVAGIPPLVQPAASVPAVQQTLIHSHPQPALLPS
LPHTHCPEIDADTQPKAPGIDDIKTLEEKLRSLFSEHSSSGAPHASVSLDTSLAMETAVT
PGLPTTAVAPGKLMTSTTSTCLPPASLPLGTTGSSVIPAVTPGQVSTPVSTVPGVKPGTA
APKPPLTKPPVLPVGTELPAGTPPSEQLPPFPGPSLTQPQQPLGDLDAQLRRTLSPETVV
LTSAVGPVSVVAPTAVVEAGAQLQKDVSQVTEGPILAPTSGTGVFKMGRFQVSVAMDDPQ
KEGKNKSEDVKSVHFESSTSESSVLSSSSPESTLVKPEPNGIAVRGVSSDMPDSARKTPA
SEATSEAGQPTKVGRFQVTTTASKVGRFSVSRAEDEITEAKKEGPVVSPPFLDLGHDVLP
AVIPKKEKPELSEASHLNGPSSDLEAAFLGRDVDDGSGSPHSPQLSSKSLPVQGLSHSFN
SSYVSSDNESDIEDEDLKSELRRLREKHLKEIQDLQSRQKHEIESLYTKLGKVPPAVIIP
PAAPLAGRRRRPTKSKGSKSSRSSSLGNKSPGPGNLSGQSAASVLHPQQTLPAPGNVPET
GQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGGTVSSQAAQAQPP
AMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMSYEGPGMARKFSAPGQLCVSMT
STLGGSAPISAASATSLGHFPKPMCPPQQYGFPAPPFGPQWSGTGGPATQPLSQFQPVGT
ASLQNFNISNLQKSISNPPGSNLRTT
NT seq 7101 nt   +upstreamnt  +downstreamnt
atgtctggcggcgccgccgaccagcagagcagcgcgccgggctccctgttcctctcgccg
ccggcgcctgcccccaagaatggctccagttcggactcctcggtgggagagaaactgggc
gccgcggcggccgacgccggagccggcaggacggaggagtaccggcgtcgccgccacacc
atggacaaggacagccggggggcggttgcgaccaccaccacggagcaccgcttcttccgc
cgcagcgtcatctgcgactccaacgccacggcgctggagctgcccggcctccccctcccg
ctgccccagacgagcgcggccgcggtggtcccgcagcggagccccccggagccccagcgc
gaggagaccctgacccccgctgccgcccatgtggcccagcagccgcccgccgccgccgcc
gcccccggggagccggtcgccgcggtcccagccgccgcctcggccccgggcagcgccggc
agagaccgccaggttgcccagcccggccacgcggggagcaaagaggagcctccgtcgtcg
agaagtggcagcggcggcggcagcgccaaggaaccccaggaggaacggagccagcagcag
gatgacatcgaagagctggagaccaaggccgtgggaatgtccaatgatggccgctttctc
aagtttgacatcgagatcggcaggggctcctttaagacggtctacaaaggtctggacacc
gaaaccaccgtggaggtcgcctggtgtgaactgcaggatcgaaagttaacaaagtctgag
aggcagagatttaaagaagaggctgaaatgttaaagggtcttcagcatcccaatattgtc
cgattctatgattcctgggaatccacagtaaagggaaagaagtgcatcgttttggtgact
gaacttatgacatctggaacacttaaaacgtacctgaaaaggtttaaggtgatgaagatc
aaagttctgagaagctggtgccgtcagattcttaaaggacttcagtttcttcatactcga
actccacctattattcaccgggatcttaagtgtgacaacatctttatcactggccctaca
ggctcagtcaagattggagacctaggtctggcaaccctgaagcgggcttcttttgccaag
agtgtgataggtaccccagagttcatggcccctgagatgtatgaggagaaatatgatgaa
tccgttgatgtttatgcttttgggatgtgcatgcttgagatggccacatctgaataccct
tactccgagtgccaaaatgctgcgcagatctaccgtcgagtgaccagtggggtgaagccg
gccagttttgacaaagtagcaattcccgaagtgaaggaaattattgaaggatgcatacga
caaaacaaagatgaaagatactctatcaaagaccttttgaaccatgccttcttccaggag
gaaacaggggtacgggtagaattagcagaagaagatgatggcgaaaagatagccattaaa
ttatggctacgtattgaagatagtaagaaattaaaggggaaatacaaagacaatgaagct
attgagttttcctttgacttggagagagatgtgccagaagacgttgctcaagaaatggta
gactctgggtatgtctgtgaaggtgatcacaagaccatggcaaaagccatcaaagataga
gtgtcattaattaagagaaagcgagaacagcgtcagttggtgcgggaggagcaagaaaaa
agaaagcaggaagagagcagcctcaaacagcagggggagcagcagtccagtgcttcccag
gcaggagcccagcagcccccttccacgtgcactggcggacctgctgcctctaccacttca
gcttctgtttccacacaagtagagccggaggagcctgaggcagatcagcaccaacagctg
caacaccagccacctggtgtgtctgtgttgtctgacgggacggttgacagtggtcaggga
tcttctgtcttcacagagtctcgagtgagcagccaacagacagtttcgtatggttcccag
catgagcaggcacattccactggcaccctcccagggcacacagcgcctgttgtccaagca
caggctcagccccatggggtatatccaccctcaagcatggcacaggggcagagccagggt
cagcaatcttcaagtagtttaacaggggtttcatcctcccaacccatacaacattctcag
cagcagcaaggagtgcagcagacagccccctctcagcagacagcgcagtattcacttccc
cagacgtcagcctccagtgaggccatgactgcacagcccgcaagtcagcctcaacctcca
cagtccttgtcgcatgtgtcagcaggaaaacagcttccagtttcccagccagtaccaact
atccaaggcgaacctcacatcccagttgcgacacagccctcagttgttccagtccattct
ggtgctcacttcctccctgcgggacagccactcccgccttcctcactcccccagtaccct
gtctctcagatcccctcagcttctcagccagctttctctccccttcctgtcaccatggca
gctggcgttaatcagcctctgcttaccttggcttcctctgctccagcagctgcagtccca
gggggaccccccctggtccctaatcttcccaccctcctgcagcctgtgactcagctgcca
aatcaggctcacccgcagctcctgcagccagcagttcagtccatggggatagccgctaac
ctcgggcagactgctgaggctccactcccctctggagatgttctctaccagggcttccca
cctcggccgccaccacagcacccaggagactcaaagcttgctccctcttccagcgtgcct
tctgtgtgcgttccttccacagtcctgtcccctcccgcgccggcagaagcactggctgca
ccaggttactttcctacagtggtgcagccttatgtggaatcaagccttttggttcctgtg
ggcagtataggaggacaggttcaagtgtcccagccagcagtgagtttagcacaagccccc
actacatcctcccagcaagcagctctggagagcactcagggcgtctctcaggtggctcct
ccagagccagttccagtggctcagccacaacctacccagcctgctacattggtctcttct
gtagacagtgcacattcagatgttgcttcaggtatgagtgatggcaatgagaatgtccca
tcatccagtggaaggcatgaagggagaactacaaaacggcattatcgaaaatctgtaaga
agtcgctctcgtcatgaaaagacttcacgcccaaaattgagaattttgaatgtttcgaat
aaaggagaccgggtagtggaatgtcagttagagactcacaatcggaaaatggttacattc
aaatttgatttagatggtgacaaccctgaggagatagcaacaattatggtgaacaatgac
tttattctggcaatggagagagaggcatttgtggaacaagtgcgggatattattgaaaaa
gctgatgaaatgctcagtgaggacgtcagtgtggagccagagggtgaccagggattggag
agtctccagggaaaggatgactatggctttgcaggctctcaaaaattggaaggagagttc
aaacaaccaattcctgcatcttccatgccacagcaaataggccttcctaccagttcttta
actcaagttgttcattctgccggaagacggtttatagtaagtcctgtgccagaaagtcga
ttacgagaatcaaaaattttcagtgaagtatcagatacagttgctgctcctacatctgct
ggcgctggaatgagcttgtctcactctgcttcatcccttagtctacagcaggccttttct
gagcttagacgtgcgcacacggcagaagggccgagcacagcacctgccaacttccgtccg
acggggccggcgttcccagcggtgcccccttccgtgatcagccctgctggagctccagcc
acagcggcagctgtaccctcagcgtcaacccctgccatgggctgccctcctagtgaccct
tccacatcagccgttcagtctgaggttgcagtgcccgctgaaaaggggattgctggagtt
gccacctgcacaggcataataccctccagtggtctccctgcaccacctgcatctgaatcc
ccgatactctccagcgtggtgtcgagcatcacggcgcctgcagtcgtctcagtatcagcg
acatcccagtcagttcaggctcccacacctgggagcgttgtttccagtacaggcacattc
ccccctgtaccagtctcagtgacggcagcctctgcagcgagcagtgctgctgccccaggc
gctaagccttcacctgtatcgtcgcagcaggtggtgggcagcatggctggggcagccacg
ctaacatccgtgtcggccacggctccagtcccgagcctagctgcacagccgtcccttcca
cccagcagcagcacctctgctcttactcgagctgagactgtagtggttagtgcgcacgca
ctggataagatatctcacggcagcctgactgggttggctttgtccctccccgcgtcacct
tcctctccctccctgggagcaggggtatcgagtgctgttgctcagcctggcgtggctcac
cctttggtcatcccatcagctgtggcttctactcctgccctttcccaggcaggacctcct
tgcacacctttccttccccaagtagctggtatcccacctttggtgcaacctgctgccagt
gtgcctgctgtacagcagacactcattcatagtcatcctcagccagctttgcttcccagc
ctgccccatactcactgtcctgaaatagatgctgatactcaacccaaagctcctgggatt
gatgacataaagacgttagaggaaaagctacggtctctcttcagtgagcacagctcatct
ggagctccgcatgcttctgtctcgctggacacgtccctcgccatggagaccgccgtcacc
ccaggcctcccaaccactgctgttgcaccaggcaaactcatgacttccactacaagtact
tgcttaccaccagccagtttgcccttaggaacaactggttcgtcagttataccagcggtc
actcctgggcaagtctccaccccagtcagcactgtaccaggagtgaaacctggaactgct
gcaccaaagccacctttaactaagcctccagtgctgccagtgggtactgaacttccagct
ggtactccacccagcgagcagctgccaccttttccaggaccttcactaacgcagccccag
cagcccctgggagatctggatgctcagctgagaagaacactcagtccagagacggttgtg
ctgacgtctgcagttggtcccgtgtccgtggtggcgccaacagcagttgtggaagcagga
gcccagcttcagaaggatgtgtctcaagtcacagaagggcctatcctagcacccacttca
ggaactggtgtttttaagatggggcgatttcaggtttcagttgcaatggatgatccccag
aaagagggtaaaaataagtcagaagatgtaaagtctgttcattttgaatccagtacttca
gagtcctcagtgctatcaagcagtagtccagagagtaccctggtgaagccagagcccaat
ggcatagctgtccgtggcgtctcttcagatatgccggatagcgcccgtaaaactcctgcc
tcagaagcaacgtcagaagctgggcagcctaccaaggttggacgttttcaggtgacaacc
acagcaagcaaagtcggtcgtttctccgtctcaagagccgaagacgagattactgaggca
aagaaggagggaccagtggtatctcctccttttctggatttgggacatgatgttcttcct
gctgtgataccaaagaaagagaagcccgaactgtcagaggcttcacatctgaacgggccg
tcctctgacctggaggctgccttcctcggtcgggatgtggacgatggctcagggagtcca
cactccccgcagctgagctcaaagagcctccctgtccagggcctgagtcattccttcaac
tcctcttacgtgagcagcgacaatgaatcagatattgaagatgaggacttgaagtcagag
ctgcggcggctacgagaaaaacatcttaaagagattcaagacctgcagagtcgccagaag
catgaaatcgaatctttgtataccaaactgggcaaggttcctcctgccgtcatcattccc
ccagctgccccccttgcagggagaagaaggcgacccaccaaaagcaaaggcagcaagtct
agtcgcagcagttccttggggaataaaagccctggaccaggtaacctgtctggccagagt
gcagcttctgtcctgcacccccagcagaccctccccgctcctggcaacgtcccagagacg
gggcagaatcagctgttacagccccttaagccatctccctccagtgacaacctgtattca
gccttcaccagtgatggtgccatttcagtaccaagcctttctgctccaggtcaagggacc
agcagcacaaacaccgttgggggaacagtgagcagccaggccgcccaggctcagcctcct
gccatgacgtccagcaggaagggcacgttcacagatgacctgcacaagttggtggacaac
tgggcccgagacgccatgaatctctcaggcaggagaggaagcaaaggacacatgagttat
gagggccctggcatggcaaggaagttctccgcacctggtcagctgtgcgtctccatgacc
tcaaccctgggtggctccgcccccatctctgcagcatcagctacctctctaggccacttc
cccaagcccatgtgccccccacagcagtacggtttcccagcccccccctttggcccgcag
tggagcggcacgggcggcccagcaacacagccacttagccagttccaacctgtgggaact
gcctccttacagaacttcaacatcagcaacttgcagaagtccatcagcaaccccccaggt
tccaacctgaggaccacttag

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