Propithecus coquereli (Coquerel's sifaka): 105805290
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Entry
105805290 CDS
T08746
Symbol
CACNA1D
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D isoform X1
KO
K04851
voltage-dependent calcium channel L type alpha-1D
Organism
pcoq
Propithecus coquereli (Coquerel's sifaka)
Pathway
pcoq04010
MAPK signaling pathway
pcoq04020
Calcium signaling pathway
pcoq04022
cGMP-PKG signaling pathway
pcoq04024
cAMP signaling pathway
pcoq04218
Cellular senescence
pcoq04260
Cardiac muscle contraction
pcoq04261
Adrenergic signaling in cardiomyocytes
pcoq04270
Vascular smooth muscle contraction
pcoq04530
Tight junction
pcoq04713
Circadian entrainment
pcoq04723
Retrograde endocannabinoid signaling
pcoq04724
Glutamatergic synapse
pcoq04725
Cholinergic synapse
pcoq04726
Serotonergic synapse
pcoq04727
GABAergic synapse
pcoq04728
Dopaminergic synapse
pcoq04911
Insulin secretion
pcoq04912
GnRH signaling pathway
pcoq04921
Oxytocin signaling pathway
pcoq04924
Renin secretion
pcoq04925
Aldosterone synthesis and secretion
pcoq04927
Cortisol synthesis and secretion
pcoq04929
GnRH secretion
pcoq04930
Type II diabetes mellitus
pcoq04934
Cushing syndrome
pcoq04935
Growth hormone synthesis, secretion and action
pcoq04973
Carbohydrate digestion and absorption
pcoq05010
Alzheimer disease
pcoq05020
Prion disease
pcoq05022
Pathways of neurodegeneration - multiple diseases
pcoq05031
Amphetamine addiction
pcoq05207
Chemical carcinogenesis - receptor activation
pcoq05410
Hypertrophic cardiomyopathy
pcoq05412
Arrhythmogenic right ventricular cardiomyopathy
pcoq05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pcoq00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105805290 (CACNA1D)
04020 Calcium signaling pathway
105805290 (CACNA1D)
04024 cAMP signaling pathway
105805290 (CACNA1D)
04022 cGMP-PKG signaling pathway
105805290 (CACNA1D)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
105805290 (CACNA1D)
09144 Cellular community - eukaryotes
04530 Tight junction
105805290 (CACNA1D)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
105805290 (CACNA1D)
04929 GnRH secretion
105805290 (CACNA1D)
04912 GnRH signaling pathway
105805290 (CACNA1D)
04921 Oxytocin signaling pathway
105805290 (CACNA1D)
04935 Growth hormone synthesis, secretion and action
105805290 (CACNA1D)
04924 Renin secretion
105805290 (CACNA1D)
04925 Aldosterone synthesis and secretion
105805290 (CACNA1D)
04927 Cortisol synthesis and secretion
105805290 (CACNA1D)
09153 Circulatory system
04260 Cardiac muscle contraction
105805290 (CACNA1D)
04261 Adrenergic signaling in cardiomyocytes
105805290 (CACNA1D)
04270 Vascular smooth muscle contraction
105805290 (CACNA1D)
09154 Digestive system
04973 Carbohydrate digestion and absorption
105805290 (CACNA1D)
09156 Nervous system
04724 Glutamatergic synapse
105805290 (CACNA1D)
04727 GABAergic synapse
105805290 (CACNA1D)
04725 Cholinergic synapse
105805290 (CACNA1D)
04728 Dopaminergic synapse
105805290 (CACNA1D)
04726 Serotonergic synapse
105805290 (CACNA1D)
04723 Retrograde endocannabinoid signaling
105805290 (CACNA1D)
09159 Environmental adaptation
04713 Circadian entrainment
105805290 (CACNA1D)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
105805290 (CACNA1D)
09164 Neurodegenerative disease
05010 Alzheimer disease
105805290 (CACNA1D)
05020 Prion disease
105805290 (CACNA1D)
05022 Pathways of neurodegeneration - multiple diseases
105805290 (CACNA1D)
09165 Substance dependence
05031 Amphetamine addiction
105805290 (CACNA1D)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
105805290 (CACNA1D)
05412 Arrhythmogenic right ventricular cardiomyopathy
105805290 (CACNA1D)
05414 Dilated cardiomyopathy
105805290 (CACNA1D)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105805290 (CACNA1D)
04934 Cushing syndrome
105805290 (CACNA1D)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pcoq04040
]
105805290 (CACNA1D)
Ion channels [BR:
pcoq04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
105805290 (CACNA1D)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
CAC1F_C
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
105805290
NCBI-ProteinID:
XP_012493620
Ensembl:
ENSPCOG00000018170
UniProt:
A0A2K6FGQ4
LinkDB
All DBs
Position
Unknown
AA seq
2180 aa
AA seq
DB search
MMMMMMMKKMQHQRQQQTDHANEANYARGTRLPLSGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVEWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFLADSDIVAEEDPAPCAFSGNGRQCTANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGGEEGKRNTSMPTSETESVNTENVS
GEGETQGCCGSLWCWWRRRGAAKAGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELEIMSPLGISVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNKPEVNQIANSDNKVTIDDYREEDEDKDPYPPC
DVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCHK
LINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTTF
GAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKGL
KHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFIL
YKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGPV
YNHRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYALK
ARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDILN
MVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADPTESENVPVPT
ATPGNSEESNRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLF
FIYAVIGMQMFGKVAMKDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLC
DPESDYSPGEEYTCGSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH
LDEFKRIWSEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSD
GTVMFNATLFALVRTALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEV
TVGKFYATFLIQDYFRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCD
LQDDEPEETKREEEEDVFKRNGALLGNHVNHVNSDRRDSLQQTNTTHRPLHVQRPSIPPA
SDTEKPLFPPAGNSVCHNHHNHNSIGKHIPTSTNANLNNANMSKAAHGKRPSLGNLELVS
ENGHHSSHKHDREPQRRSSIKRTRYYETYIRSDSGDEQLPTICREDPEIHGYFRDPRCLG
EQEYFSSEECYEDDSSPPGSRQTYGYYSRYTGSNSDFERPRGYPYPQGFLEDDDSPVCYD
SRRSPRRRLLPPTPTSHRRSSFNFECLRRQGSQEEVPLSPAFPHRTALPLHLMQQQIMAV
AGLDSSKAQKYSPSHSTRSWVTPPATPPYRDWTPCYTPLIQVDRSESLDQVNGSLPSLHR
SSWYTDEPDISYRTFTPASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFV
SATKHEIADACDLTIDEMESAASTLLNGSVHPRANGDLGPISHRQDYELQDFGPGYSDDE
PDPGREEEDLADEMICITTL
NT seq
6543 nt
NT seq
+upstream
nt +downstream
nt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaaacggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctctttctggtgaaggaccaact
tctcagccgaatagctccaagcaaactgtcctgtcttggcaagctgcaatcgatgctgct
agacaggccaaggctgcccaaactatgagcacctctgcacccccacctgtaggatctctc
tcccaaagaaaacgacagcaatacgccaagagcaaaaaacagggtaactcgtccaacagc
cgacctgcccgcgcccttttctgtttgtcactcaataaccccatccgaagagcctgcatt
agtatagtggaatggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccattccccgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtcgagacatttttgaagatt
atagcgtatggattattgctgcatcctaatgcttatgttaggaatggatggaatttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagcggcaaatcaggaggctttgatgtcaaagccctccgt
gcctttcgagtgttacgaccacttcgactagtgtcaggagtgcccagtttacaagttgtc
ctgaactccattataaaagccatggttcccctccttcacatagcccttttggtattattt
gtaatcataatctatgctattataggattggaactttttattggaaaaatgcacaaaaca
tgttttcttgctgactcagatatcgtcgctgaagaggacccagctccatgtgcgttctca
gggaatggacgccagtgtaccgccaacggcacggaatgtaggagcggctgggtcggcccg
aacggaggcatcaccaactttgataactttgcctttgccatgctcactgtgtttcagtgc
atcaccatggagggctggacagatgtgctctactgggtaaatgatgcgataggatgggaa
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattttcaaaggaaagagagaaggctaaagcacgggga
gacttccagaagctccgggagaagcagcagctggaagaggatctaaagggctacttggat
tggattacccaagcagaagatatcgatcctgagaatgaggatgaaggaggagaggaaggc
aaacgaaatactagcatgcccaccagtgagaccgagtctgtgaacacggagaacgtgagt
ggcgaaggcgagacccagggctgctgcggaagtctctggtgctggtggagaagaagaggt
gcggccaaggctgggccctctgggtgtcggcggtggggtcaagccatctcaaaatccaaa
ctcagtcgacgctggcgtcgctggaaccggttcaatcgcagaagatgtagggctgccgtg
aagtctgtcacattttactggctggttattgtcctggtgtttctcaacaccttaaccatt
tcctccgagcactacaaccagccagattggttgacacagattcaagatattgctaacaaa
gtcctcttggctctgttcacctgcgagatgctggtaaaaatgtacagcttgggcctccaa
gcatatttcgtctctcttttcaaccggttcgattgcttcgtggtgtgcggcggaattact
gaaaccatcttagtggaactggaaatcatgtctcccctgggcatctccgtgtttcggtgt
gtgcgcctcttaagaatcttcaaagtgaccaggcactggacttccctgagcaacttagtg
gcatccctgttaaactccatgaagtccatcgcttcgctgctgcttctgctttttctcttc
atcatcatcttttccttgctcgggatgcagctgtttggcggcaagtttaatttcgatgaa
acgcaaaccaagcggagcaccttcgacaatttccctcaagcacttctcacggtgttccag
atcctgacaggtgaagactggaatgctgtgatgtacgacggcatcatggcttatgggggc
ccgtcctcttcaggaatgattgtctgcatctacttcatcatcctcttcatttgtggtaac
tatatcctactgaacgtcttcttggccattgctgtagacaatttggctgatgctgaaagt
ctgaacactgctcagaaagaagaagcagaagaaaaggaaaggaaaaagattgccagaaaa
gagagcttagaaaataaaaagaacaaaccagaagtcaaccagatagccaacagtgacaac
aaggttacaattgacgactaccgagaagaggatgaagacaaggacccctacccaccttgt
gacgtgccagtaggtgaagaggaagaagaggaggaggaggatgaacctgaggttcctgct
ggtccccgtcctcgcagaatctcagagttgaacatgaaggagaaaatcgcccccatccct
gaagggagcgctttcttcattctcagcaagaccaacccgatccgcgtgggctgccacaag
ctcatcaaccaccacatcttcaccaacctcatcctcgtcttcatcatgctgagcagcgcc
gccctcgccgccgaggaccccatccgcagccactccttccggaatactatactgggttac
tttgactatgccttcacagccatctttactgttgagatcctgttgaagatgacaaccttt
ggcgctttcctccacaaaggggctttctgcaggaactacttcaatttgctggacatgctg
gttgttggggtgtctctggtgtcatttgggattcaatccagtgccatctccgtggtgaag
attctgagggtcttaagggttctgaggcccctcagggcaatcaacagagcaaaaggactt
aagcacgtggtccagtgtgtctttgtggccatccggaccatcggcaacatcatgatcgtc
accaccctcctccagttcatgtttgcctgcattggggtccagctgttcaaggggaagttc
tatcgctgcacagatgaagccaaaagtaaccctgaagagtgcagggggcttttcatcctc
tacaaggatggggacgttgacagccctgtggtccgtgagcggatctggcagaacagtgac
ttcaactttgacaacgtcctctctgccatgatggcactcttcaccgtctccacgtttgag
ggctggcccgcgttgctgtataaagctatcgactcgaatggagagaacgtcggcccagtc
tacaaccaccgcgtggagatctccatcttcttcatcatctacatcatcatcgtagctttc
ttcatgatgaacatctttgtgggctttgtcatcgttacatttcaggagcagggggaaaaa
gagtataagaactgtgagctggacaagaatcagcgtcagtgtgttgaatacgccttgaaa
gcacgtcccttgcggagatacatccccaaaaacccctaccagtacaagttctggtacgtg
gtgaactcttcgcctttcgaatacatgatgtttgtcctcatcatgctcaacacactctgc
ttggccatgcagcactacgagcagtccaagatgttcaacgacgccatggacattctgaac
atggtcttcactggagtgttcaccgttgagatggttttgaaagtcattgcatttaagcct
aaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagcatt
atagacgtggccctcagcgaagcagacccaactgaaagtgaaaatgtccctgtcccaact
gctacacctgggaactctgaagaaagcaatagaatctccatcacctttttccgtcttttc
cgagtgatgcgattggtgaagcttctcagtaggggggaaggcatccggacgctgctgtgg
accttcattaagtcgtttcaggcgctcccgtacgtcgccctgctcatagccatgctgttc
ttcatctacgcggtcatcggcatgcagatgtttgggaaagttgccatgaaagataacaac
cagatcaacaggaacaacaacttccagacgtttccgcaggcagtgctgctgctcttcagg
tgtgcaacgggcgaggcctggcaagagatcatgctggcctgcctcccagggaagctctgt
gaccctgagtcggattacagccccggggaggagtatacgtgtgggagcaactttgccatc
gtctatttcatcagcttttacatgctctgtgcatttctgatcatcaatctgtttgtggct
gtcattatggacaattttgattatctgacccgggactggtctattctggggcctcaccac
ttagatgaattcaaaagaatatggtcagaatatgaccctgaggcgaagggaaggataaaa
cacctcgacgtggtcactctgctccggcgcatccagcctcccctggggtttgggaagtta
tgtccacacagagtggcatgcaagagattggttgccatgaacatgcctctcaacagtgat
gggacggtcatgtttaatgcaactctctttgctttggttcgaacggctcttaagatcaag
acagaagggaacctggaacaagctaatgaagaactccgggctgtgataaagaaaatctgg
aagaaaaccagcatgaaactgctagaccaagttgtccctccagctggtgatgatgaggta
accgtggggaagttctatgccactttcctgatacaggactactttaggaaattcaagaaa
cggaaagaacaaggactggtgggaaagtaccctgcgaagaacaccacaattgccctacag
gcgggattaaggacactgcatgacattgggccagaaatccggcgtgccatatcatgtgat
ttgcaagacgatgagcccgaagaaacaaaacgagaggaagaagaagatgtattcaaaaga
aatggtgccctgcttggaaaccatgtcaatcatgttaatagtgataggagagattccctt
cagcagaccaataccacccaccgtcccctgcatgtccaaaggccttcaattccacctgca
agtgatactgagaaaccgctgtttcctccagcaggaaattcggtgtgtcataaccatcat
aaccataattccataggaaagcacattcccacctcaacaaatgccaatctcaataatgcc
aatatgtccaaagctgcccatggaaagcggcccagccttgggaaccttgagcttgtgtct
gaaaatgggcatcattcctcccacaagcatgatcgggagcctcaaagaaggtccagtatc
aaaagaacccgctattatgaaacttacattagatctgactcgggagatgagcagctccca
actatttgccgggaagacccagagatccacggctacttcagggacccccgctgcctgggg
gagcaggaatatttcagcagcgaggagtgctatgaggacgacagctcgccacccgggagc
aggcaaacctatggctactacagcaggtacacaggcagcaactcggacttcgagaggccc
cggggctacccttacccccaaggcttcctggaggacgacgactcccctgtctgctatgat
tcacggagatctccaaggagacgcctactacctcccaccccaacatcccaccggagatcc
tccttcaacttcgagtgcctgcgccggcagggcagccaggaggaggtcccactgtctcct
gccttcccccaccgcacggccctgcctctgcacctgatgcagcaacagatcatggcagtt
gcgggcctagattcgagtaaagcccagaagtactcgccaagtcactcaacccggtcctgg
gtcacccctccagcaacccctccgtaccgggactggacaccatgctacaccccgctgatc
caggtggatcggtcagagtccctggaccaggtcaacggcagcctgccgtccctgcaccgc
agctcctggtacacagatgagcccgacatctcctatcggactttcacaccagccagcctg
accgtccccagcagcttccggaacaagaacagcgacaagcagaggagtgcggacagcttg
gtggaggcggtcctgatatctgaaggcttaggccgctatgcaagggacccaaaatttgtg
tcagcaacaaaacacgaaatcgccgatgcctgtgacctgaccatcgatgagatggagagt
gcggccagcaccctgcttaacggcagcgtgcatccccgagccaacggggacctgggcccc
atctcacaccggcaggactacgagctccaggactttggtcccggctacagcgacgacgag
ccagacccggggagagaggaggaggacctggcagatgagatgatatgcatcaccaccttg
tag
DBGET
integrated database retrieval system
