KEGG   Phascolarctos cinereus (koala): 110199045
Entry
110199045         CDS       T05867                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4 isoform X1
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw04010  MAPK signaling pathway
pcw04064  NF-kappa B signaling pathway
pcw04620  Toll-like receptor signaling pathway
pcw04621  NOD-like receptor signaling pathway
pcw04722  Neurotrophin signaling pathway
pcw04936  Alcoholic liver disease
pcw05132  Salmonella infection
pcw05133  Pertussis
pcw05135  Yersinia infection
pcw05140  Leishmaniasis
pcw05142  Chagas disease
pcw05145  Toxoplasmosis
pcw05152  Tuberculosis
pcw05161  Hepatitis B
pcw05162  Measles
pcw05164  Influenza A
pcw05168  Herpes simplex virus 1 infection
pcw05169  Epstein-Barr virus infection
pcw05170  Human immunodeficiency virus 1 infection
pcw05171  Coronavirus disease - COVID-19
pcw05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110199045 (IRAK4)
   04064 NF-kappa B signaling pathway
    110199045 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    110199045 (IRAK4)
   04621 NOD-like receptor signaling pathway
    110199045 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    110199045 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    110199045 (IRAK4)
   05161 Hepatitis B
    110199045 (IRAK4)
   05171 Coronavirus disease - COVID-19
    110199045 (IRAK4)
   05164 Influenza A
    110199045 (IRAK4)
   05162 Measles
    110199045 (IRAK4)
   05168 Herpes simplex virus 1 infection
    110199045 (IRAK4)
   05169 Epstein-Barr virus infection
    110199045 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    110199045 (IRAK4)
   05135 Yersinia infection
    110199045 (IRAK4)
   05133 Pertussis
    110199045 (IRAK4)
   05152 Tuberculosis
    110199045 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    110199045 (IRAK4)
   05140 Leishmaniasis
    110199045 (IRAK4)
   05142 Chagas disease
    110199045 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    110199045 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    110199045 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcw01001]
    110199045 (IRAK4)
Enzymes [BR:pcw01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     110199045 (IRAK4)
Protein kinases [BR:pcw01001]
 Serine/threonine kinases: TKL group
  IRAK family
   110199045 (IRAK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Pkinase_fungal Death
Other DBs
NCBI-GeneID: 110199045
NCBI-ProteinID: XP_020829386
UniProt: A0A6P5J503
LinkDB
Position
Unknown
AA seq 463 aa
MNKTITSSTYVRCLNVGLIRQLADFIDPQEGWKKLAVDIKKPSGDSRYNQFHIRRFEGLL
QTGKSPTSELLFDWGTTNCTVGDLVDLLIRNEFLAPARLLLPVNFADNVPENVHILPQEA
VQKKLLPLYDEEKTYVKPVFIQNHEQISSPLDSSSPDMKSLEVSDTCFQSFSFYELKSIT
NNFNEHPISAGGNKMGEGGFGVVYKGCINNRTVAVKKLTNMADMCTEELKQQFEQEIKIM
AECQHENLVELLGFSSDNDSFCLVYVYMPNGSLLDRLSCLDGTAPLSWHTRCNIAQGTAN
GICYLHANHHVHRDIKSANILLDEDFIPKISDFGLSRTSAKFNQTVMTSRIVGTTAYMAP
EALRGEITPKSDIYSFGVVLLEIITGLPAVDEQREPQLLLDIREEIEDEEKHIEDYIDAK
MKDVDSISVENMYSIANLCLHEKKNKRPDIEMVKQHLQEMTSS
NT seq 1392 nt   +upstreamnt  +downstreamnt
atgaataagacaataacttcatcaacatatgtaaggtgcctaaatgttggcctgattagg
cagctggcagattttattgatcctcaggaaggatggaagaagttagcagttgatataaaa
aagccttctggagatagtagatataaccaatttcatataaggagatttgaaggattactt
caaactggaaagagtcccactagtgaactactctttgactggggaaccacaaattgtaca
gttggagaccttgtagatcttttaatcagaaatgaatttctagccccagcacgtctgttg
ctgccagttaactttgcagataatgttccagaaaatgttcatatacttccacaagaagcc
gttcaaaagaaattgctgcctctttatgatgaagaaaagacatatgtgaaacctgtattt
attcagaatcatgaacaaatctcttcacctctggactcctcaagtccagacatgaaaagt
ttagaagttagcgatacatgttttcagagtttttcattttatgaattaaaaagtattaca
aataactttaatgagcaccctatatcagctggtggaaacaaaatgggagaaggaggcttt
ggagttgtatataaaggctgtatcaataacagaaccgtggcagtgaagaaacttacaaat
atggctgatatgtgtacagaagaactaaaacaacagtttgagcaagaaataaaaattatg
gcagagtgtcaacatgaaaacctagtggaactacttggcttctcaagtgataatgacagc
ttctgcttggtatatgtctatatgcctaatggttcgttgcttgacagactatcttgtctg
gatggtactgcaccactttcctggcatacaagatgcaatattgctcaaggtacagctaat
ggcatctgctatttacatgcaaaccatcatgttcatagagatattaaaagtgcaaatatt
ttacttgatgaggacttcatacccaagatttctgactttggactttcacgaacttctgca
aaatttaaccaaacagtcatgactagcagaattgtgggaacaacagcctatatggcacct
gaagctttgcgaggggagataacacctaaatctgacatttatagctttggtgtggtcttg
ctagaaataataactggacttccagcagtggatgagcaacgtgaacctcaattattgcta
gatatcagagaggaaatcgaagatgaagaaaagcatattgaagattatattgatgcaaaa
atgaaggatgtggattccatttctgttgaaaatatgtattctattgccaatctttgtctt
catgaaaagaaaaacaagagaccagacattgagatggtaaaacagcacctccaagagatg
acatcatcctga

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