KEGG   Phascolarctos cinereus (koala): 110214178
Entry
110214178         CDS       T05867                                 
Symbol
PRKACA
Name
(RefSeq) cAMP-dependent protein kinase catalytic subunit alpha isoform X1
  KO
K04345  protein kinase A [EC:2.7.11.11]
Organism
pcw  Phascolarctos cinereus (koala)
Pathway
pcw01522  Endocrine resistance
pcw04010  MAPK signaling pathway
pcw04014  Ras signaling pathway
pcw04020  Calcium signaling pathway
pcw04024  cAMP signaling pathway
pcw04062  Chemokine signaling pathway
pcw04114  Oocyte meiosis
pcw04140  Autophagy - animal
pcw04211  Longevity regulating pathway
pcw04213  Longevity regulating pathway - multiple species
pcw04261  Adrenergic signaling in cardiomyocytes
pcw04270  Vascular smooth muscle contraction
pcw04310  Wnt signaling pathway
pcw04340  Hedgehog signaling pathway
pcw04371  Apelin signaling pathway
pcw04530  Tight junction
pcw04540  Gap junction
pcw04611  Platelet activation
pcw04713  Circadian entrainment
pcw04714  Thermogenesis
pcw04720  Long-term potentiation
pcw04723  Retrograde endocannabinoid signaling
pcw04724  Glutamatergic synapse
pcw04725  Cholinergic synapse
pcw04726  Serotonergic synapse
pcw04727  GABAergic synapse
pcw04728  Dopaminergic synapse
pcw04740  Olfactory transduction
pcw04742  Taste transduction
pcw04750  Inflammatory mediator regulation of TRP channels
pcw04910  Insulin signaling pathway
pcw04911  Insulin secretion
pcw04912  GnRH signaling pathway
pcw04913  Ovarian steroidogenesis
pcw04914  Progesterone-mediated oocyte maturation
pcw04915  Estrogen signaling pathway
pcw04916  Melanogenesis
pcw04918  Thyroid hormone synthesis
pcw04919  Thyroid hormone signaling pathway
pcw04921  Oxytocin signaling pathway
pcw04922  Glucagon signaling pathway
pcw04923  Regulation of lipolysis in adipocytes
pcw04924  Renin secretion
pcw04925  Aldosterone synthesis and secretion
pcw04926  Relaxin signaling pathway
pcw04927  Cortisol synthesis and secretion
pcw04928  Parathyroid hormone synthesis, secretion and action
pcw04934  Cushing syndrome
pcw04935  Growth hormone synthesis, secretion and action
pcw04961  Endocrine and other factor-regulated calcium reabsorption
pcw04962  Vasopressin-regulated water reabsorption
pcw04970  Salivary secretion
pcw04971  Gastric acid secretion
pcw04976  Bile secretion
pcw05012  Parkinson disease
pcw05020  Prion disease
pcw05030  Cocaine addiction
pcw05031  Amphetamine addiction
pcw05032  Morphine addiction
pcw05034  Alcoholism
pcw05146  Amoebiasis
pcw05163  Human cytomegalovirus infection
pcw05165  Human papillomavirus infection
pcw05166  Human T-cell leukemia virus 1 infection
pcw05200  Pathways in cancer
pcw05203  Viral carcinogenesis
pcw05205  Proteoglycans in cancer
pcw05207  Chemical carcinogenesis - receptor activation
pcw05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:pcw00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    110214178 (PRKACA)
   04014 Ras signaling pathway
    110214178 (PRKACA)
   04310 Wnt signaling pathway
    110214178 (PRKACA)
   04340 Hedgehog signaling pathway
    110214178 (PRKACA)
   04371 Apelin signaling pathway
    110214178 (PRKACA)
   04020 Calcium signaling pathway
    110214178 (PRKACA)
   04024 cAMP signaling pathway
    110214178 (PRKACA)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    110214178 (PRKACA)
  09143 Cell growth and death
   04114 Oocyte meiosis
    110214178 (PRKACA)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    110214178 (PRKACA)
   04540 Gap junction
    110214178 (PRKACA)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    110214178 (PRKACA)
   04062 Chemokine signaling pathway
    110214178 (PRKACA)
  09152 Endocrine system
   04911 Insulin secretion
    110214178 (PRKACA)
   04910 Insulin signaling pathway
    110214178 (PRKACA)
   04922 Glucagon signaling pathway
    110214178 (PRKACA)
   04923 Regulation of lipolysis in adipocytes
    110214178 (PRKACA)
   04912 GnRH signaling pathway
    110214178 (PRKACA)
   04913 Ovarian steroidogenesis
    110214178 (PRKACA)
   04915 Estrogen signaling pathway
    110214178 (PRKACA)
   04914 Progesterone-mediated oocyte maturation
    110214178 (PRKACA)
   04921 Oxytocin signaling pathway
    110214178 (PRKACA)
   04926 Relaxin signaling pathway
    110214178 (PRKACA)
   04935 Growth hormone synthesis, secretion and action
    110214178 (PRKACA)
   04918 Thyroid hormone synthesis
    110214178 (PRKACA)
   04919 Thyroid hormone signaling pathway
    110214178 (PRKACA)
   04928 Parathyroid hormone synthesis, secretion and action
    110214178 (PRKACA)
   04916 Melanogenesis
    110214178 (PRKACA)
   04924 Renin secretion
    110214178 (PRKACA)
   04925 Aldosterone synthesis and secretion
    110214178 (PRKACA)
   04927 Cortisol synthesis and secretion
    110214178 (PRKACA)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    110214178 (PRKACA)
   04270 Vascular smooth muscle contraction
    110214178 (PRKACA)
  09154 Digestive system
   04970 Salivary secretion
    110214178 (PRKACA)
   04971 Gastric acid secretion
    110214178 (PRKACA)
   04976 Bile secretion
    110214178 (PRKACA)
  09155 Excretory system
   04962 Vasopressin-regulated water reabsorption
    110214178 (PRKACA)
   04961 Endocrine and other factor-regulated calcium reabsorption
    110214178 (PRKACA)
  09156 Nervous system
   04724 Glutamatergic synapse
    110214178 (PRKACA)
   04727 GABAergic synapse
    110214178 (PRKACA)
   04725 Cholinergic synapse
    110214178 (PRKACA)
   04728 Dopaminergic synapse
    110214178 (PRKACA)
   04726 Serotonergic synapse
    110214178 (PRKACA)
   04720 Long-term potentiation
    110214178 (PRKACA)
   04723 Retrograde endocannabinoid signaling
    110214178 (PRKACA)
  09157 Sensory system
   04740 Olfactory transduction
    110214178 (PRKACA)
   04742 Taste transduction
    110214178 (PRKACA)
   04750 Inflammatory mediator regulation of TRP channels
    110214178 (PRKACA)
  09149 Aging
   04211 Longevity regulating pathway
    110214178 (PRKACA)
   04213 Longevity regulating pathway - multiple species
    110214178 (PRKACA)
  09159 Environmental adaptation
   04713 Circadian entrainment
    110214178 (PRKACA)
   04714 Thermogenesis
    110214178 (PRKACA)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    110214178 (PRKACA)
   05205 Proteoglycans in cancer
    110214178 (PRKACA)
   05207 Chemical carcinogenesis - receptor activation
    110214178 (PRKACA)
   05203 Viral carcinogenesis
    110214178 (PRKACA)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    110214178 (PRKACA)
   05163 Human cytomegalovirus infection
    110214178 (PRKACA)
   05165 Human papillomavirus infection
    110214178 (PRKACA)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    110214178 (PRKACA)
  09164 Neurodegenerative disease
   05012 Parkinson disease
    110214178 (PRKACA)
   05020 Prion disease
    110214178 (PRKACA)
  09165 Substance dependence
   05030 Cocaine addiction
    110214178 (PRKACA)
   05031 Amphetamine addiction
    110214178 (PRKACA)
   05032 Morphine addiction
    110214178 (PRKACA)
   05034 Alcoholism
    110214178 (PRKACA)
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy
    110214178 (PRKACA)
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    110214178 (PRKACA)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    110214178 (PRKACA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pcw01001]
    110214178 (PRKACA)
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis [BR:pcw03019]
    110214178 (PRKACA)
   03036 Chromosome and associated proteins [BR:pcw03036]
    110214178 (PRKACA)
Enzymes [BR:pcw01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.11  cAMP-dependent protein kinase
     110214178 (PRKACA)
Protein kinases [BR:pcw01001]
 Serine/threonine kinases: AGC group
  PKA family
   110214178 (PRKACA)
Messenger RNA biogenesis [BR:pcw03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     110214178 (PRKACA)
Chromosome and associated proteins [BR:pcw03036]
 Eukaryotic type
  Centrosome formation proteins
   Kinases and associated factors
    110214178 (PRKACA)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_C Ins145_P3_rec Haspin_kinase
Other DBs
NCBI-GeneID: 110214178
NCBI-ProteinID: XP_020850596
UniProt: A0A6P5L4S0
LinkDB
Position
Unknown
AA seq 352 aa
MGNAATAKKGNELESVKEFLAKAKEEFLKKWESPPQQSTVQLDHFERIKTLGTGSFGRVI
LVKHKESGKYFAMKVLDKQKVVKLKQIEHTMNEKRILQAINFPFLVLLEYSFKDNTNLYM
VMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQG
YIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPF
FADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRYGNLKNGVNDIKNHKWFS
TTDWIAIYQRKVEAPFIPKCKGPGDTSNFDDYEEEELRISINEKCAKEFAEF
NT seq 1059 nt   +upstreamnt  +downstreamnt
atggggaacgcggccaccgccaagaagggcaacgagctggagagcgtgaaagagtttcta
gctaaagccaaagaagaattcctcaagaaatgggaaagtccacctcagcagagtacagtc
cagctggatcattttgaaagaatcaagactctaggcactggttcctttggtcgagtgata
cttgtgaagcacaaggaatctgggaagtactttgccatgaaagtccttgataaacagaag
gtggtgaagctgaaacaaatcgagcacaccatgaatgagaagcgcatcctgcaggccatc
aacttcccattcctcgtcctactagaatattccttcaaggacaacacaaacctgtacatg
gtgatggagtatgtcccaggtggggaaatgttctcccacctccggcggatcggaaggttc
agtgagccccatgctcgcttttacgcagctcagattgtcctgacctttgaataccttcac
tcactggacctgatctaccgagacctgaagcccgagaatcttctcattgaccagcagggc
tatatccaggtgacagattttggttttgccaagcgtgtgaaaggccgaacctggacctta
tgtgggactcctgagtacctggctcctgagatcatccttagcaagggctataataaggct
gtggactggtgggccctaggcgtcctgatctatgagatggcagcaggctacccccccttc
tttgctgaccagcccatccagatttatgaaaagattgtctctgggaaggttcgattccct
tctcacttcagctccgacctaaaggacctgcttcggaacctgctccaagtggacctcacc
aagcgctacgggaacctcaagaatggtgtcaacgacatcaagaaccacaaatggttctcc
accaccgactggatcgccatctaccagaggaaggtggaagctccctttataccaaagtgc
aaaggccccggtgacacaagtaatttcgatgattacgaggaggaggagctccggatctcc
atcaatgagaagtgcgccaaggagtttgctgagttctaa

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