KEGG   Phyllostomus discolor (pale spear-nosed bat): 114490278
Entry
114490278         CDS       T07739                                 
Symbol
RYR3
Name
(RefSeq) LOW QUALITY PROTEIN: ryanodine receptor 3
  KO
K04963  ryanodine receptor 3
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04020  Calcium signaling pathway
pdic04371  Apelin signaling pathway
pdic04713  Circadian entrainment
pdic04921  Oxytocin signaling pathway
pdic04970  Salivary secretion
pdic05010  Alzheimer disease
pdic05012  Parkinson disease
pdic05020  Prion disease
pdic05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    114490278 (RYR3)
   04020 Calcium signaling pathway
    114490278 (RYR3)
 09150 Organismal Systems
  09152 Endocrine system
   04921 Oxytocin signaling pathway
    114490278 (RYR3)
  09154 Digestive system
   04970 Salivary secretion
    114490278 (RYR3)
  09159 Environmental adaptation
   04713 Circadian entrainment
    114490278 (RYR3)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    114490278 (RYR3)
   05012 Parkinson disease
    114490278 (RYR3)
   05020 Prion disease
    114490278 (RYR3)
   05022 Pathways of neurodegeneration - multiple diseases
    114490278 (RYR3)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:pdic04040]
    114490278 (RYR3)
Ion channels [BR:pdic04040]
 Voltage-gated cation channels
  Ryanodine receptor
   114490278 (RYR3)
SSDB
Motif
Pfam: RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 MIR SPRY Ins145_P3_rec RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_8 EF-hand_5
Other DBs
NCBI-GeneID: 114490278
NCBI-ProteinID: XP_035887266
UniProt: A0A7E6E6Q4
LinkDB
Position
1:complement(147947258..148449311)
AA seq 4863 aa
MAEGGEGGEDEIQFLRTEDEVVLQCIASIHKEQRKFCLAAEGLGNRLCFLEPTSEAKFVP
PDLCVCSFVLEQSLSVRALQEMLASTGENGGEGAAQGGGHRTLLYGHAILLRHSFSEMYL
TCLTTSRSQTDKLAFDVGLQEHATGEACWWTIHPASKQRSEGEKVRIGDDLILVSVSSER
YLHLSISNANIQVDASFMQTLWNVHPTCSGSSIEEGYLLGGHVVRLFHGHDECLTIPSTD
QNDAQHRRIFYEAGGAGTRARSLWRVEPLRISWSGSNIRWGQAFRLRHLTTGHYLALTED
QGLILQDRGKSDTKATAFSFRASKEIKEKLDSSHKRDIEGMGVPEIKYGDSVCFVQHVAS
GLWVTYKAQDAKTSRLGPLKRKVILHQEGHMDDGLTLQRCQREESQAARIIRNTTALFSQ
FISGNNRTAAPITLPIEEVLQTLQDLITYFQPQRRRCSMKDKQNKLRSLKNRQXLFKEEG
MLALVLNCIDRLNIYNSVAHFAGIAREESGMAWKEILNLLYKLLAALIRGNRNNCAQFSN
NLDWLISKLDRLESSSGILEVLHCILMESPEALNLIAEGHIKSIISLLDKHGRNHKVLDV
LCSLCLCNGVAVRTNQNLICDNLLPRRNLLLQTRLINDVTSIRPNIFLGVAEGSAQYKKW
YFELIIDQVDPFLTAEPTHLRVGWASSSGYAPYPGGGEGWGGNGVGDDLYSYGFDGLHLW
SGRIPRAVASINQHLLKSDDVVSCCLDLGVPSISFRINGQPVQGMFENFNTDGLFFPVVS
FSAGVKVRFLMGGRHGEFKFLPPSGYAPCYEALLPKEKMRLEPVKEYKRDTEGIRDLLGT
TQFLSQASFIPCPIDTSQVVLPPHLEKIRDRLAENIHELWGMNKIELGWTFGKIRDDNKR
QHPCLVEFSKLPETEKNYNLQMSTETLKTLLALGCHIVHVNPAAEEDLKKVKLSKNYMMS
NGYKPAPLDLSDVKLLPPQEILVDKLAENAHNVWAKDRIKQGWTYGIQQDVKNKRNPRLV
PYSLLDERTKKSNRDSLREAVRTFIGYGYNIEPSDQELADPAVEKVSIDKIRFFRVERSY
AVRSGKWYFEFEVVTGGDMRVGWARPGCRPDVELGADDQAFVFEGSKGQRWHQGSGYFGR
TWQPGDVVGCMINLDDASMIFTLNGELLITNKGSELAFADYEIENGFVPICSLGLSQIGR
MNLGMDASTFKFYTMCGLQEGFEPFAVNMNRDVAMWFSKRLPTFVNVPKDHPHIEVMRID
STMDSPPCLKVTHKTFGTQNSNASMIYCRLSMPVECHSSFSHSPCMDGDAFQKRKQMQEI
LSQTTTQCYYAIRIFAGQDPSCVWVGWVTPDYHLYSEKFDLNKNCTVTVTLGDERGRVHE
SVKRSNCYMVWGGDIVATSQRSSRSNVDLEIGCLVDLAMGMLSFSANGRELGTCYQVEPN
TKVFPAVFLQPTSTSLFQFELGKLKNAMPLSAAIFKSEEKNLVPQCPPRLDVQTIQPVLW
SRMPSSFLKVETERVSERHGWVVQCLEPLQMMALHIPEENRCVDILELCEQEDLLQFHYH
TLRLYSAVCALGNSRVAYALCSHVDLSQLFYAIDNKYLPGLLRSGFYDLLISIHLANAKE
RKLMMKNEYIIPITSTTRKIRLYPDGSKKHGLPGVGLRTCLKPGFQFSTPCFVMTSEEHQ
KQSPEIPLEILKTKALSMLREAVECSGAHIRDPVGGSVEFQFVPVLKLIGTLLVMGVFDD
DDVRQILLLVDPSVFGEQSREREEGAEKEEVSQVEEKAVEAGEKASKEAPVKGLLQTRLP
ESVKLQMCELLSYFCDCELQHRVEAIVAFGDIYVSKLQANQKFRYNELMQALNMSAALTA
RKTKEFRSPPQEQINMLLNFQLGENCPCPDEIREELYDFHEDLLSHCGVPLEEEEEEEEV
TSWAGKLCALVQKIKGPKPETEQPAVEEQKCPTTLKELISQTMIRWAQEDHIQDADLVRM
MFNLLRRQYDSIGELLQALRKTYSISQASVGDTINLLAALGQIRCLLSVRMGKEEELLMI
NGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGAEKSQIAFPKMVASCCRFLCYFC
RISRQNQKAMFEHLSYLLENSSVGLASPSMRGSTPLDVAASSVMDNNELALGLEEPDLEK
VVTYLAGCGLQSCPMLLAKGYPDVGWNPIEGERYLSFLRFAVFVNGESVEENASVVVKLL
IRRPECFGPALRGEGGNGLLAAMQGAIRISENPALDLPSQGYKREVSMEDGEDEEEIVHM
GNAIMSFYSALIDLLGRCAPEMHLIQTGKGEAIRIRSILRSLVPTEDLVGIISIPLKLPS
LNKDGSVSQPDVAAHFCPDHKAPMVLFLDRVYGIKDQTFLLHLLEVGFLPDLRTSASLDT
VSLSTTEAALALNRYICSAVLPLLTRCAPLFAGTEHYTSLIDSTLQTIYRLSKGRSLTKA
QRDTIEECLLAICNHLRPSMLQQLLRRLVFDVPQLNEHCTMPLKLLTNHYEQCWKYYCLP
SGWGSYGLAVEEELHLTEKLFWGIFDSLSHKKYDPDLFRMALPCLSAIAGALPPDYLDTR
ISATLEKQLSVDADGNFDPKPISTLNFSLPEKLEYIVTKYAEHSHDKWACEKSQNGWKYG
ISLDENVKTHPLIRPFKTLTEKEKEIYRWPARESLKTMLAVGWTVERTKEGEALVQQREN
EKLRSTSQASQGNSYSPAPLDLSNVALSRELQGMVEVIAENYHNIWAKKKKLELESKGGG
SHPLLVPYDTLTAKEKFRDREKAQDLFKFLQVNGIVVSRGVKDMELDASSMEKRFAYKFL
KKILKYVDSAQEFIAHLEALVSSGKTERSPHDQEIKFFAKVLLPLVDQYFTNHRLYFLSS
PLKPLSSGGYASHKEKEMVASLFCKLAALVRHRISLFGSDSTTMVSCLHILAQTLDTRTV
MKSGSELVKAGLRAFFENAAEDLEKTSENLKLGKFTHSRTQIKGVSQNINYTTVALLPIL
TSIFEHVAQHQFGVDLLLGDVQISCYHILCSLYSLGTGRNIYVERQRPALGECLASLAAA
IPVAFLEPTLNRYNPLSVFNTKTPRERSILGMPDTVEEMCPDIPQLEGLMKEINDLAESG
ARYTEMPHVIEVILPMLCNYLSYWWEQGPEHLPPGTGPWCTRVTSEHLSVILGNILKIIN
NNLGIDEASWMKRIAVYAQPIISKARPDLLRSHFIPTLEKLKKKAVKTVQEEEQLKADSK
GDTQEAELLILDEFAVLCRDLYAFYPMLIRYVDNNRSNWLKSPDADSDQLFRMVAEVFIL
WCKSNNFKREEQNFVIQNEINNLAFLTGDSKSKMSKSGGQDQERKKTKRRGDLYSVQTSL
IVAALKKMLPIGLNMCTPGDQELISLAKSRYSLRDTDEEVKEHLRNNLHLQEKSDDPAVK
WQLNLYKDVLKSEEPSDPEKTVERVQRISAAVFHLEQVEQPLRSKKAVWHKLLSKQRKRA
VVACFRMAPLYNLPRHRSINLFLHGYQRFWIETEECSFEERLVQDLAQSPKAEEQEEEEM
ERHPDPLHQIILHFSRNALTERSKLEDDPLYTSYSSMMAKSCRNGENEEEEEDKEKTFEE
KEMEKQKTLYQQARLHERGAAEMVLQMISASKGEMSPMVVETLKLGIAILNGGNAGVQQK
MLDYLKEKKDAGFFQSLSGLMQSCSVLDLNAFERQNKAEGLGMVTEEGTLIVRERGEKVL
QNDEFTRDLFRFLQLLCEGHNSDFQNFLRTQMGNTTTVNIIISTVDYLLRLQESISDFYW
YYSGKDIIDESGQHNFSKALVVTKQIFNSLTEYIQGPCIGNQQSLAHSRLWDAVVGFLHV
FANMQMKLSQDSSQIELLKELLDLLQDMVVMLLSLLEGNVVNGTIGKQMVDTLVESSTNV
EMILKFFDMFLKLKDLTSSDAFKEYDPDGKGIISKKEFQKAMEGQKQYTPSEIDFLLSCA
EADENDMFNYIDFVDRFHEPAKDIGFNVAVLLTNLSEHMPNDSRLKCLLDPAESVLNYFE
PYLGRIEIMGGAKKIERVYFEISECSRTQWEKPQVKESKRQFIFDVVNEGGEQEKMELFV
NFCEDTIFEMQLASQISESDSADRPEEEEDDEGSSYTLEIEGEEEDDKSSEPASAFAMAC
ASVKRSVANFLKRATLKNLRKQYRKVKKMAVKELVKVFFSFFWMLFVGLFRLFFTILGGI
VQVLWNTVFGGGLVEGAKNIRVTKILGDMPDPTQFGIHDDTMEAERAEATEPGVSTELVH
FIKGEKGDVDIMSDLFGVYSKKEGGLKHGPEVGLGDLSEIAGKDEPPTLESTVRKKRKAQ
AAEMRAAHESEGKVEPEKADMEDGEKEDPAREEQAKALWAEATKKKKRRHGQKVEKPEAF
MANFFKGLEIYQTKLLHYLARNFYNLRFLALFVAFAINFILLFYKVTEEPLEEEAEDVAN
LWHSFNDEEEEEAMVFFVLQESTGYMAPTLRALAIAHTVISLVCVVGYYCLKVPLVVFKR
EKEIARKLEFDGLYITEQPSEDDIKGQWDRLVINTPSFPNNYWDKFVKRKVINKYGDLYG
AERIAELLGLDKNALDFSPVEKTKAEAASLVSWLSSIDMKYHIWKLGVVFTDNSFLYLAW
YTTMSVLGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVV
AFNFFRKFYNKSEDDDEPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYEMYRI
VFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVREDMETKCFICGIGNDYFDTTPHG
FETHTLQEHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWDFFPAGDCFRKQYED
QLG
NT seq 14592 nt   +upstreamnt  +downstreamnt
atggccgaagggggagaaggcggcgaggacgagatccagttcctgcggactgaagatgaa
gtggttctccagtgcatcgcaagcattcacaaggagcaaaggaagttctgcctggcagct
gagggacttggcaatcgcctgtgcttcttggaacccacttcagaagccaagtttgttcct
ccagacctctgtgtctgcagttttgtgctggaacagtccctgtcggtcagagccctgcag
gagatgcttgccagcacaggggaaaatggcggtgaaggggcagcacaagggggtgggcac
aggactctgctatatggccacgcgattctcctgcgacactcctttagtgaaatgtatctg
acatgtttgactacgtcaagatcccagacagataaacttgcctttgatgtaggtctacaa
gaacatgccacaggagaagcctgttggtggaccatacatcccgcttccaaacagaggtct
gaaggagaaaaagttcgaattggagatgacctcatccttgtcagcgtgtcctctgaaaga
taccttcatctctcaatatcaaatgctaacatacaagtggatgcctcctttatgcaaaca
ctctggaatgtacatcctacgtgctcaggaagcagcatcgaagaaggatacctacttgga
gggcatgtagtacgtcttttccatggtcatgatgagtgtttgacgataccatctaccgat
cagaatgacgcccagcacaggagaatattctatgaagctgggggagctgggacacgagcc
agatctctgtggagagtggaaccccttcggattagctggagtggcagtaacatcagatgg
ggccaggctttccgactgcggcatctcaccacaggccactacctggccttgacagaggac
caaggcctaatactgcaagaccggggaaagtcagacaccaaggctacagccttctccttc
agggcatcaaaggaaatcaaggagaaactggattccagtcacaaaagagatatagaaggc
atgggagttccagaaatcaagtatggagattccgtgtgctttgtccagcatgtagccagt
ggtctgtgggtgacctacaaagcacaagatgccaagacatcccgccttggacctctgaaa
agaaaggtcatactccaccaggaaggccacatggatgatggcttaacactgcagagatgc
cagcgtgaggaatcccaggcggcccgcatcatccgcaacacaacagccttattcagccag
ttcataagtggaaacaatcgcacagctgcccccatcaccctgccgatagaagaggtcctg
cagaccttgcaggacttgatcacctacttccagccccagaggaggagatgcagcatgaag
gacaaacagaacaagctccgctcactcaaaaacagacagnatcttttcaaggaagaggga
atgttggcgcttgtgttaaattgcattgaccgcttaaacatctacaacagcgttgcacac
tttgcagggatcgcaagggaagagagtggcatggcctggaaggaaattctgaacctcctg
tacaaattgctggctgccctcatccgtggaaacagaaacaattgcgctcaattctccaat
aaccttgactggctaatcagcaaattggacagactagaatcttcctcaggtatcttggaa
gtcttacactgcatcctgatggaaagcccagaagccttaaacctgatagcagagggccac
atcaagtccatcatctccctgctggataagcatggacggaaccacaaggttctggatgtg
ctgtgctccctctgtctctgcaacggggtcgcagtgagaaccaaccagaacctcatctgc
gacaacctgctgccccggagaaacctgctgctgcagacacggctgattaacgacgtgacg
agtattcgaccaaacatcttcctgggagtcgctgagggctcagcacagtacaaaaagtgg
tacttcgagctcattatcgaccaggtggaccccttcctaacagcagagcccacacacctg
cgggtgggctgggcctcttcctcaggctatgctccataccccggaggcggagaaggatgg
ggaggcaacggtgttggggatgacctgtattcctatggctttgatggacttcacctttgg
tcaggtcgcattcccagagctgtggcctccatcaaccagcacctcctgaagtccgatgac
gtggtgagctgttgcctggaccttggtgtgcccagcatctctttccgcatcaacggacag
cctgtgcaggggatgtttgagaatttcaacacagatgggctcttcttccctgtggtgagc
ttttcagcaggtgtcaaagtacgtttcctgatgggtggacgtcatggagaatttaagttt
ctgcctccctccggttatgccccttgctatgaagccttacttccaaaggaaaagatgaga
ttggagcctgtcaaagaatataagcgtgacaccgaaggcatcagagatctgctgggaacc
acccagttcctctcccaagcctccttcatcccatgccccatagacaccagccaggtggtt
ttgccacctcacctagagaagatccgagacagactggctgaaaatatccatgagctttgg
ggaatgaacaaaatagagcttggctggacttttggcaagatacgggatgacaataaaaga
caacacccctgcctagtagagttttcaaagctgcccgaaaccgagaagaattataaccta
caaatgtcaactgaaaccttaaaaacgctcctagccttggggtgccacattgttcatgtg
aatccagccgctgaagaggacctcaagaaggtcaaactgtccaaaaactacatgatgtcc
aatggctataagccagcccctttggatttgtctgatgtgaagctattacctcctcaggaa
attttagtggataagcttgcagaaaatgcacataatgtctgggcaaaagacagaataaaa
caaggatggacctatggcattcaacaggatgtgaagaacaaaagaaatccccgtctggtg
ccatattcattactggatgagcgtaccaagaagtcaaacagggacagccttcgtgaagct
gttcgaacatttattggttatggctataacatcgagccgtccgaccaagaactagctgac
ccagctgtggagaaagtcagcatagacaagatccgatttttccgggtagagcggtcttat
gcagtgagatctggaaagtggtattttgagttcgaggtggtgactggaggagacatgcgt
gttggctgggccaggccaggctgtcggcctgatgttgagctgggggccgatgaccaagcc
tttgtgtttgaaggcagcaagggccagcgctggcatcaagggagtgggtatttcggacgt
acctggcaaccaggagatgtggttggatgtatgattaacctggatgatgcttcaatgatc
ttcacactaaatggggagctgctgatcaccaacaaaggctcagaacttgccttcgcagat
tacgagattgagaatggctttgtgcccatctgctccctgggactgtctcagatcggccgt
atgaacctcgggatggacgccagtaccttcaagttttataccatgtgcggcctccaagag
ggctttgagccttttgctgtcaacatgaaccgagatgttgcaatgtggttcagcaagcgc
ctcccgacgtttgtcaacgtgccaaaggatcatccccatatagaggtcatgaggattgac
agcaccatggacagccccccatgcctcaaggtgacacacaagacatttggcacccagaat
agcaatgccagcatgatctactgccgcctgagcatgcccgtggaatgccactcctccttc
agccacagcccctgtatggatggtgatgctttccagaaaaggaagcagatgcaagaaata
ctctctcaaacaacaacacagtgctactatgcaatccgcatctttgccgggcaggaccca
tcctgtgtttgggtcggatgggtgactccggactatcacttatacagtgaaaagtttgac
ctgaataaaaactgtacggtgactgttactctgggggatgaaagaggccgggtccatgaa
agtgtaaagcgcagcaactgctacatggtttggggtggggacatcgtggctacttcccaa
cggtcaagtcgcagcaacgtggacctggagatcggctgcctcgtggatctggcaatgggc
atgttgtccttctcagccaacgggagagaacttggcacctgttaccaggtggagcccaac
accaaagtgtttccagcagtcttcctgcagcccacaagcacttctctgtttcagtttgaa
cttggaaagctgaagaatgcgatgcccctgtcggcagccatatttaagagtgaagagaag
aacctagtcccacagtgtccgcctcggctagatgtgcaaaccatccagcccgtgctctgg
agccgcatgcccagcagcttcctgaaggtggagacagagcgggtgagcgagcgccacggc
tgggtggtgcagtgcctggagcccctgcagatgatggcgctccacatcccggaagagaac
aggtgtgtggatatcctggagctctgtgagcaagaggacctgctgcagttccattaccac
acgctgagactctacagcgccgtgtgcgccctgggaaacagccgagtagcctatgccctg
tgcagccacgtggacctttcccagctcttctacgccattgataacaagtacctccccggc
ctccttcggtctggcttctatgacctgctcatcagcatccatctggccaacgctaaggag
agaaagctgatgatgaagaatgagtacatcatccccattaccagcaccaccaggaaaatc
cgcctgtacccagatgggtcaaagaagcacgggctgcctggggtgggcctgagaacttgc
ctcaagccgggcttccagttctccaccccttgctttgtcatgaccagtgaggagcaccag
aagcagagccctgagattcccttggagattctcaagacgaaggcactgagcatgctgaga
gaggctgtggagtgcagtggagctcacatccgagaccctgttgggggctctgtggagttc
cagtttgtgcctgtgctgaagctcattggaactctgctggtcatgggggtgtttgatgat
gatgacgttcggcagattctcctcctggttgatccttctgtgtttggcgagcagagtagg
gagagagaagaaggagcagagaaggaggaagtgagtcaggtggaggagaaggcagtggag
gctggggaaaaggccagcaaggaggctccagtgaaaggcttgttacagacccgattacca
gagtccgtcaagctccagatgtgtgagctcctcagctatttctgtgactgtgagctgcag
caccgagtggaagccattgtggcctttggtgacatttatgtctccaagctccaggcaaat
cagaagttccgctacaatgagctcatgcaggccctgaacatgtctgcagccctgactgct
cggaagaccaaggagttccgctcacctccacaggagcagatcaacatgctccttaacttt
caactgggagagaactgcccctgcccagatgagatccgggaggagctgtacgacttccat
gaggaccttctctctcactgtggggtccccctggaggaagaggaggaggaggaggaggtc
acctcctgggcaggcaaactctgtgccttggtgcagaaaatcaaaggccccaagccagaa
acagagcagccggcggtggaggagcaaaagtgccctacaacactgaaggaactcatctca
cagaccatgatccgctgggcccaggaagaccacattcaggatgcagacctcgtccggatg
atgttcaacctcctccggaggcagtacgacagcatcggggagctgctgcaggccctgagg
aagacctacagcatcagccaggcctctgtgggtgacaccatcaacctgctggcagccctg
ggccagatccgctgcctcctcagcgtcaggatgggcaaggaagaggagctgctcatgatc
aacgggctgggagatataatgaacaacaaggtgttttaccagcaccccaacctcatgcga
gttctcggcatgcacgagacggtgatggaggtgatggtgaacgtgctgggtgcagagaaa
tcccagattgcttttccaaagatggtcgctagctgttgccgcttcctctgctatttctgt
cgaattagccggcagaatcagaaggccatgttcgagcatctaagttacctgttggagaat
agcagtgttggcctagcctctccatcaatgaggggatccactccactggatgtggcagct
tcctcagtgatggacaacaatgagttagcactgggcttagaggaaccagacctcgagaag
gtggtgacttacttggcaggctgtggcctacagagctgccccatgcttctggccaaagga
taccctgacgtcggctggaaccccattgaaggggagcggtacctgtccttcctgaggttt
gccgtctttgtgaacggtgaaagtgtggaagaaaatgctagtgtcgtggtcaagctgctc
atcagacgcccagagtgctttggtccggccctgaggggtgaaggggggaatggcctgttg
gccgccatgcagggagccatcaggatctcagagaacccagccctcgacctcccctcgcag
ggatacaagagagaagtcagcatggaggacggtgaagacgaagaagagatcgtgcacatg
ggcaacgcaattatgtcattttattcagctcttatagatctgctgggccgctgtgctcct
gaaatgcaccttatccagacaggaaaaggcgaagctatccggatcaggtcaatcctacgc
tccctggtccccactgaggacttggttggaatcatcagcatccccttgaaactgccctca
ctgaacaaagacgggtccgtcagccagccggacgtggccgcccacttctgcccggaccac
aaggcacccatggtgctgttcctggaccgtgtgtacggcattaaggatcaaacgtttctg
ctccacttgctggaggtcggatttttacccgacttaagaacctctgcctctctagataca
gtttccctgagcaccacggaggctgcgctggcactgaatcggtacatatgttctgctgtg
ctcccgctcctcacaagatgcgcccctctctttgctggaacagaacactacacctctctg
atcgattctacactccagacaatatacaggctttccaagggacgttccctcaccaaagct
cagagggacaccatagaagaatgtttgcttgctatttgcaatcacctgaggccttccatg
ctgcagcagctcctgcggcgcctggtgttcgacgtgccccagctcaacgagcactgcaca
atgcccctgaagcttctgacgaatcactatgagcagtgctggaagtactactgtctgccg
tcggggtgggggagctacggcctcgctgtggaggaagagctgcacctgacagagaagctc
ttctgggggatcttcgattccctgtcccacaagaagtacgacccagacctcttccggatg
gccctgccctgtcttagcgccatagccggggccttgccgccagactacttagacaccagg
atctcggccacgctggagaaacagctctcagtggatgcagatggcaacttcgaccccaag
cctatcagcaccctgaatttctccttgcctgaaaaattggagtacatcgtcaccaagtat
gctgagcactcacatgacaaatgggcctgtgaaaagagtcagaatggatggaaatatgga
atttcgctggacgaaaacgtgaagacccatccgctgataaggcctttcaagacattaaca
gagaaggagaaggaaatttatcgctggccagccagagagtccctgaaaaccatgctggct
gtgggctggactgtggagaggaccaaagaaggagaagcccttgttcaacaacgggaaaat
gagaagcttcgaagcacatcccaggccagccagggcaacagctacagccccgctcccctg
gacctctccaacgtggcgctctcccgagagctccagggaatggtggaggtcatagctgag
aactatcacaacatctgggccaagaagaagaagctggagctggagagcaaaggtggtggc
agtcaccctcttttggtaccatacgacaccctgaccgccaaggagaagtttagggaccga
gagaaggcacaggacctgtttaaattcctccaagtgaatggcattgtggtttccagaggt
gtgaaggacatggagctggatgcctcctccatggagaagaggtttgcctataaatttttg
aagaagatcctgaaatacgttgattctgctcaagagtttattgcacacttggaagccctt
gtcagcagtgggaaaactgaaaggtctcctcatgaccaggagatcaaattctttgccaaa
gttctcctcccgctggttgaccagtacttcaccaaccaccgcctctacttcctgtcgtcc
cctctgaagcccctcagcagcggtgggtatgcctcccataaggaaaaagagatggtggcc
agcctgttctgcaaactcgctgctctcgttcggcacaggatttccctctttgggagcgat
tctactacaatggtgagctgccttcatatcttagctcagacgctcgacacaaggaccgtc
atgaagtcgggctcagagctggtgaaggccgggttacgagccttctttgaaaatgccgca
gaagacttagagaagacttcggaaaacctgaagctcgggaagttcacgcactccagaacg
cagattaaaggcgtctctcagaacattaactacaccacggtggcgctgctccccatcctg
acgtccatctttgagcacgtggcgcagcatcagtttggggtggatttgctcttgggtgac
gtgcagatttcatgctaccacatactgtgcagcctctactcccttgggacgggaaggaac
atctatgttgaaagacaacgtcccgccctcggagaatgtctggcttcactggcagctgcc
atcccagtggcgttcctggagcccacccttaaccgttacaacccgctctcagtcttcaac
accaaaacccccagggagagatctattctggggatgccagacacagtggaagagatgtgt
cctgacatcccccagctggaaggcctcatgaaagaaatcaacgacctggccgagtcaggg
gcccggtacacagagatgccccacgtcatcgaggtgatcctgcccatgctctgcaactac
ctgtcctactggtgggagcaggggcctgagcacctgccccccggcacagggccctggtgc
accagagtcacctcggaacacctcagtgtcatcctgggcaacatcctgaaaatcatcaac
aacaacctgggcatcgatgaggcctcctggatgaagcgtattgcagtgtatgcccagcca
atcatcagcaaagccaggcctgacctgctaagaagtcacttcatcccaactctggagaag
ctgaagaaaaaggccgtcaagactgtgcaagaggaggagcagctgaaggccgacagcaaa
ggggacacccaggaggcagagctcctcatcctggatgagtttgcagtgctctgcagagac
ctctacgccttctaccccatgctgatccgctacgtggacaacaacagatctaattggctc
aaaagccctgatgctgattctgaccagctcttccgcatggtggcagaggtcttcatcctg
tggtgcaaatcgaacaacttcaagagggaagagcaaaattttgtgattcagaatgaaatt
aataatttggcatttttaaccggagacagcaaaagcaagatgtcaaaatctggagggcag
gaccaggaacggaagaagaccaagcggaggggagacttgtattctgtccagacctccctc
atcgtggctgcgctcaagaagatgctgcctattggtttgaacatgtgcaccccaggcgat
caggagctgatctccctcgcaaagtcacgatacagcttgagagacacagacgaagaagtg
aaggaacacctgcggaacaacttgcacttgcaggaaaagtctgatgacccagctgtaaag
tggcaactgaacctctacaaggatgttttgaagagtgaagaaccttctgatccagaaaag
acagtggagcgtgtgcaaagaatttcagcagctgtcttccacctggagcaggtggagcag
cctttgaggtccaagaaggcagtctggcacaaactgctgtctaagcagcggaaacgggca
gtggtggcctgtttcaggatggcccctctctacaacctgcccaggcaccgctctattaac
ctcttcctccatggctatcagagattttggatagaaacagaggaatgttcctttgaagag
agactagtacaggatttggctcagtctcccaaggcggaggagcaggaggaggaggagatg
gaaaggcatccagacccacttcatcagatcattctccattttagccgcaatgctctcacc
gagaggagcaaactggaagatgaccctttgtacacctcctattccagcatgatggccaag
agttgtcggaatggggaaaacgaggaagaggaggaggacaaggaaaaaacatttgaagaa
aaagagatggaaaagcagaaaaccctgtaccagcaggctcggctgcacgagcggggagct
gcagagatggtccttcagatgatcagcgccagcaaaggtgagatgagccccatggtggtt
gagactctgaagctggggatcgccattctgaacggaggcaacgcgggtgtgcagcagaaa
atgttagattacctaaaggagaaaaaggatgctggattctttcagagcctttctggtctt
atgcagtcttgcagtgtccttgatttgaatgcatttgagaggcagaataaagctgaaggc
ctgggcatggttactgaggaaggaacactcattgttcgtgagcgtggtgaaaaagtactc
cagaatgatgagttcacacgagatctctttagattcctacagttactttgtgaaggacat
aacagtgactttcagaacttcctgcgaactcagatgggtaacaccaccaccgtgaacatc
atcatcagcaccgtggactaccttctgcgtcttcaggaatcaatcagtgatttctactgg
tattattcagggaaggacataattgatgagtctggacagcacaatttttccaaagctctg
gtggtcaccaagcagattttcaattctcttacagaatacatccagggcccttgcattggg
aaccagcagagcctggctcacagcaggctgtgggacgcggtggtcggcttcctccacgta
tttgctaacatgcagatgaaactctcgcaggattccagtcagatcgagctgctgaaggaa
ctcttggatctccttcaggacatggtggtgatgcttctgtccctcctggaagggaatgtg
gtaaatggaactattggcaagcagatggttgacacactggtagagtcatctaccaatgta
gaaatgatcttgaaattctttgacatgttcttgaaactgaaagacttaaccagctcagat
gccttcaaagaatatgacccagatgggaaagggattatctccaaaaaagaattccagaag
gccatggaagggcaaaaacagtacacaccatcagagattgactttctcctttcatgtgca
gaagctgatgagaatgacatgtttaactacatcgattttgtagaccggttccatgagccg
gccaaggacatagggtttaacgtggcagtgctattgacaaatctgtcagagcacatgcca
aatgactctcgccttaagtgcctgttggacccagcggaaagtgtgctgaattactttgaa
ccatacctgggacgtattgagattatgggtggggccaagaaaattgagcgtgtttatttc
gagatcagtgaatgtagtcgaactcaatgggaaaagccccaagtgaaggaatctaagcga
cagttcatctttgatgttgtcaatgaaggtggagaacaggagaagatggagctgtttgtg
aacttctgtgaggataccatctttgaaatgcagttagcatctcagatctctgaatctgac
tcagcggacaggccagaagaggaggaggacgatgaaggctcttcttacacgttagaaatc
gagggtgaagaggaagatgacaagtcctccgagcctgcctctgcatttgccatggcctgc
gcctcagtgaagagaagtgttgccaactttctgaaaagggcaaccctgaagaacctcagg
aagcaataccggaaggtgaaaaagatggctgtgaaggagctggtaaaggtgtttttctct
ttcttctggatgttgttcgtggggctgttccggttgttcttcaccatactgggaggaatc
gttcaggtcctctggaacacagtgtttggagggggccttgtagaaggggcaaagaacatc
agggtgaccaagatcctgggggacatgcctgacccaacccaatttggtatccatgacgac
accatggaggctgagagggcagaagcgactgagccgggtgtctccactgaactagtacac
ttcattaagggggagaagggagatgtggatattatgtcagacctttttggagtctactca
aagaaagaaggtggcttaaagcatgggcccgaagtgggtttgggtgacctctctgagatt
gctggcaaagatgaaccccctacgctagagagtactgtacggaagaaaaggaaagcgcag
gcggcagagatgagagcagcccatgagtcagaaggaaaagtagaacctgagaaagcagac
atggaagatggggagaaggaggatccggccagagaagagcaagccaaagccctatgggca
gaagccacaaaaaagaagaagcgacggcatggccagaaagtcgagaagcctgaagccttc
atggctaatttctttaaagggctggaaatctatcagaccaagttgctgcattacctggcc
aggaatttctacaacctgaggttccttgctctgtttgtagccttcgctatcaacttcatc
ctgctcttttacaaggtcacggaagaacccctggaggaggaggcggaggacgtggcgaac
ctgtggcattcctttaatgacgaggaagaggaggaagcgatggtgttcttcgtcctgcag
gagagcaccgggtacatggccccgacgttgcgggccctggccatcgcccacacggtcatc
tctctggtctgtgtggtgggctactactgcctgaaggtccctttggtggtattcaagcga
gaaaaagaaattgccaggaagctggagtttgatggcctgtatattaccgaacagccatct
gaagatgacatcaaagggcaatgggaccgcttggtaatcaacacaccatcttttcctaat
aactactgggacaagtttgtgaagagaaaggtgataaacaagtatggtgacctctacgga
gcagaacgcattgctgaacttctgggtttggacaaaaatgcccttgactttagcccggta
gaaaagaccaaagcagaggcggcctctctggtgtcatggctaagctccatcgacatgaag
taccacatctggaagctgggagttgttttcactgacaattcctttctctaccttgcctgg
tatacgaccatgtcggtcctgggccactacaacaacttcttcttcgccgctcacctgctg
gatatcgccatgggcttcaagaccctgaggactattctatcatctgtgactcataacggc
aaacagctggttttgactgtgggtctcctggccgtggtagtttatctctacaccgtggtg
gcattcaacttcttccgcaagttctacaacaagagtgaggatgatgacgagcccgacatg
aagtgtgatgacatgatgacgtgttacctattccacatgtacgtgggagtgagagctggc
ggaggcattggcgatgaaattgaagaccctgctggtgacccctatgaaatgtaccgcatc
gtctttgacatcacctttttcttctttgtcattgtcatcttgctggccatcattcaaggt
cttattattgatgcttttggagagctgagagaccagcaggaacaagtgcgagaagatatg
gagaccaagtgtttcatctgtgggatcggcaatgactactttgacacgactcctcatggc
tttgaaacacatacattacaagagcacaacttagccaactacttgttcttcctcatgtat
ttgattaacaaagacgaaacagagcacacgggtcaggaatcttacgtctggaagatgtac
caagaaaggtgttgggatttcttcccagctggtgactgctttcggaaacaatatgaagat
cagcttggataa

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