Phyllostomus discolor (pale spear-nosed bat): 114497642
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Entry
114497642 CDS
T07739
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
pdic
Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04064
NF-kappa B signaling pathway
pdic04380
Osteoclast differentiation
pdic04650
Natural killer cell mediated cytotoxicity
pdic04658
Th1 and Th2 cell differentiation
pdic04659
Th17 cell differentiation
pdic04660
T cell receptor signaling pathway
pdic05135
Yersinia infection
pdic05166
Human T-cell leukemia virus 1 infection
pdic05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pdic05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
pdic00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
114497642 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
114497642 (LCK)
04660 T cell receptor signaling pathway
114497642 (LCK)
04658 Th1 and Th2 cell differentiation
114497642 (LCK)
04659 Th17 cell differentiation
114497642 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
114497642 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
114497642 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
114497642 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
114497642 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
114497642 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pdic01001
]
114497642 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pdic03036
]
114497642 (LCK)
Enzymes [BR:
pdic01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
114497642 (LCK)
Protein kinases [BR:
pdic01001
]
Non-receptor tyrosine kinases
SRC family
114497642 (LCK)
Chromosome and associated proteins [BR:
pdic03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
114497642 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH3_3
Kdo
SH3_16
Motif
Other DBs
NCBI-GeneID:
114497642
NCBI-ProteinID:
XP_028369285
EnsemblRapid:
ENSPDIG00005004635
UniProt:
A0A6J2LTN3
LinkDB
All DBs
Position
5:20685293..20706577
Genome browser
AA seq
509 aa
AA seq
DB search
MGCGCSSNPEDDWMENIDVCENCHYPIVPLDGKAMLPMRNGSEVRDPLVKYMDSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILERNGEWWKAQSLTTGQEGFIPYNFVAKAN
SLEPEPWFFKSLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH
YKIRNLDKGGFYISPRITFPGLHELVEHYTKNSDGLCTRLSRPCQTQKPQKPWWEDEWEV
PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL
VRLYAVVTQEPIYIITEYMENGSLVDFLKTPAGIKLTINKLLDMAAQIAEGMAFIEARNY
IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK
SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYQIMIQCWKEH
PEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1530 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtggctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgt
gagaactgccattaccccatagtcccactggatggcaaggccatgctgcccatgcggaat
ggctccgaggtgcgggacccgctggttaagtacatggactccaacccaccagcgtctcca
ctgcaagataacctggttatcgccttgcacagctacgagccctctcacgatggagacctg
ggcttcgagaagggggaacagctccgtatcctggaacggaacggtgagtggtggaaggca
cagtccctgaccaccggccaggaaggtttcatcccctacaacttcgtggccaaagcgaac
agcctggagccggaaccctggttcttcaagagcctgagccgcaaggatgcagaacggcag
ctcctggctcccgggaacacgcacggctccttcctgatccgggagagcgagagcaccgcg
ggatcgttttccctgtccgtccgggacttcgaccagaaccagggagaggtggtgaaacat
tacaagatccgtaacttggacaaaggaggcttctacatttccccccgcatcactttcccc
ggcctgcacgagctggtcgaacattacaccaaaaattctgacgggctgtgcacgcggttg
agccgcccctgccagacccagaagcctcagaagccgtggtgggaggacgagtgggaggtt
cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaggtgtgg
atggggtactacaacgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg
tcccccgacgccttcctggctgaggccaaccttatgaagcagttgcaacaccagcggctg
gtccggctctacgctgtggtcacccaggagcccatctacatcatcacggaatacatggag
aatgggagcctggtggattttctgaagacccctgcaggcatcaagctgaccatcaacaag
ctcttggatatggcagcccaaattgcagagggcatggcattcattgaagcacgcaattat
atccaccgtgacctgagggccgccaacatcctggtgtctgacaccctgagctgcaagatc
gcagattttggcctagcacgcctcatcgaggacaacgaatacacagccagggagggggcc
aagtttccaattaagtggacagcaccagaagccattaactatgggaccttcaccatcaag
tcggatgtgtggtctttcgggatcctgctgacggagattgtcacccatggccgcatccct
tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggtg
cgacctgacaactgtccggaggagctgtaccagatcatgatacagtgctggaaggagcac
cccgaggaccggcctacctttgactacctgcgcagcgtgctggaggacttcttcacagcc
acggagggccagtaccagccccagccctga
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