KEGG   Phyllostomus discolor (pale spear-nosed bat): 114515272
Entry
114515272         CDS       T07739                                 
Symbol
MAP2K3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
  KO
K04432  mitogen-activated protein kinase kinase 3 [EC:2.7.12.2]
Organism
pdic  Phyllostomus discolor (pale spear-nosed bat)
Pathway
pdic04010  MAPK signaling pathway
pdic04015  Rap1 signaling pathway
pdic04218  Cellular senescence
pdic04620  Toll-like receptor signaling pathway
pdic04664  Fc epsilon RI signaling pathway
pdic04668  TNF signaling pathway
pdic04714  Thermogenesis
pdic04750  Inflammatory mediator regulation of TRP channels
pdic04912  GnRH signaling pathway
pdic04935  Growth hormone synthesis, secretion and action
pdic04936  Alcoholic liver disease
pdic05014  Amyotrophic lateral sclerosis
pdic05022  Pathways of neurodegeneration - multiple diseases
pdic05132  Salmonella infection
pdic05135  Yersinia infection
pdic05145  Toxoplasmosis
pdic05161  Hepatitis B
pdic05169  Epstein-Barr virus infection
pdic05170  Human immunodeficiency virus 1 infection
pdic05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
pdic05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pdic00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    114515272 (MAP2K3)
   04015 Rap1 signaling pathway
    114515272 (MAP2K3)
   04668 TNF signaling pathway
    114515272 (MAP2K3)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    114515272 (MAP2K3)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    114515272 (MAP2K3)
   04664 Fc epsilon RI signaling pathway
    114515272 (MAP2K3)
  09152 Endocrine system
   04912 GnRH signaling pathway
    114515272 (MAP2K3)
   04935 Growth hormone synthesis, secretion and action
    114515272 (MAP2K3)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    114515272 (MAP2K3)
  09159 Environmental adaptation
   04714 Thermogenesis
    114515272 (MAP2K3)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    114515272 (MAP2K3)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    114515272 (MAP2K3)
   05161 Hepatitis B
    114515272 (MAP2K3)
   05169 Epstein-Barr virus infection
    114515272 (MAP2K3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    114515272 (MAP2K3)
   05135 Yersinia infection
    114515272 (MAP2K3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    114515272 (MAP2K3)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    114515272 (MAP2K3)
   05022 Pathways of neurodegeneration - multiple diseases
    114515272 (MAP2K3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    114515272 (MAP2K3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    114515272 (MAP2K3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pdic01001]
    114515272 (MAP2K3)
Enzymes [BR:pdic01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     114515272 (MAP2K3)
Protein kinases [BR:pdic01001]
 Serine/threonine kinases: STE group
  STE7 family
   114515272 (MAP2K3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Haspin_kinase Pkinase_fungal Seadorna_VP7 Choline_kinase APH DUF4344
Other DBs
NCBI-GeneID: 114515272
NCBI-ProteinID: XP_028390430
UniProt: A0A6J2NJS9
LinkDB
Position
8:complement(59834403..59863998)
AA seq 347 aa
MESPASSQPAGIPQSKGKSKRKKDLHISCVSKPPMPNPTPPRNLDSRAFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHTQSGTIMAVKRIRATVNSQEQKRLLMDLDVNMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLDKNMMIPEDILGKIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTLDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYGSWGTPFQQLKQVVEEPSPQLPADRFSPEFVD
FTAQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq 1044 nt   +upstreamnt  +downstreamnt
atggaatcccccgcctccagccaacctgctggcataccccagtccaaaggaaaatccaag
aggaagaaggacttacatatatcctgtgtgtccaagccgcccatgcccaaccccaccccc
cccaggaaccttgactcccgggctttcatcaccattggagacaggaactttgaggtagag
gctgatgacctggtgacgatctcagagctagggcgcggagcctatggcgtggtggagaaa
gtacggcacacccagagcggcaccatcatggctgttaagcggatccgggccaccgtgaac
tcccaggagcagaagcgtctgcttatggacttggatgtgaacatgcgcacggttgactgc
ttctacactgtcaccttctatggggccctcttcagagagggagatgtgtggatctgcatg
gaactcatggacacatccctggacaagttctaccgtaaagtgcttgataaaaacatgatg
attccagaggacattctggggaagattgctgtgtctatcgtgagggcgctggagcacctg
catagcaagctgtccgtgattcacagagatgtaaagccatctaatgtcctcatcaacaag
gaggggcacgtgaagatgtgtgactttgggatcagcggctacttggtagattctgtggcc
aagacactggatgccggctgcaagccctacatggctccggagagaatcaacccagaactg
aaccagaagggctacaacgttaagtctgacgtctggagcctcggcatcaccatgatcgag
atggctatcctacggtttccttatgggtcctgggggaccccattccagcagctgaagcag
gtggtggaggagccgtctccccagctcccagctgaccgtttctctcctgagtttgtggac
ttcactgcacaatgcctgaggaagaaccctgccgaacgcatgagctacctggagttgatg
gaacatcctttcttcactttgcacaaaaccaagaagacagacatcgctgcttttgtgaag
gagatcctaggagaggactcatag

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