Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1: PFREUD_02190
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Entry
PFREUD_02190 CDS
T01252
Symbol
bkdA1
Name
(GenBank) 2-oxoisovalerate dehydrogenase subunit alpha (Branched-chain alpha-keto acid dehydrogenase E1 component alpha chain) (BCKDH E1-alpha)
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
pfr
Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1
Pathway
pfr00280
Valine, leucine and isoleucine degradation
pfr00640
Propanoate metabolism
pfr00785
Lipoic acid metabolism
pfr01100
Metabolic pathways
pfr01110
Biosynthesis of secondary metabolites
pfr01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
pfr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
PFREUD_02190 (bkdA1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
PFREUD_02190 (bkdA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
PFREUD_02190 (bkdA1)
Enzymes [BR:
pfr01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
PFREUD_02190 (bkdA1)
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GFIT
Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
FimA4_C
Motif
Other DBs
NCBI-ProteinID:
CBL55734
UniProt:
D7GI12
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All DBs
Position
259807..260919
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AA seq
370 aa
AA seq
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MDSDDPTQPLQLLTPDGTLVDNPRFHWEGSDEDLVDMLRQMTTARRFDVEGAALQRHGEL
GLWAPLSGQEAYQAAVTKVMKPQDMVFGTYREQSIALQKGVPLGDILAVWRGSSLSRWIA
SDAQVAPYYMIIGAQPLHAVGYAMGVARDKAKHPTDPANDAVTLTIYGDGASSQGDVNEA
LVFAASQQAPVVFLNVNNQWAISEPSSVQTRIPLYQRAMGFGIPGIRVDGNDPLACHAVL
NWAFDEVRSGSGPVLVEAVTYRMGPHTTSDDPTKYRSSQVTEEWKAKDPIERLRSYLLER
GLIDYAWTEKLNADLDTFGALVRDTCRALPNTPMSEVFDAVTADPGLYLSEQRADCLDWL
ATPPSEGAAE
NT seq
1113 nt
NT seq
+upstream
nt +downstream
nt
atggattccgatgacccgacgcagcccctgcagctgctgacacccgacggcacgctcgtc
gacaatccacggttccactgggagggcagcgacgaggacctcgtcgacatgctgcgccag
atgaccaccgcccgccgtttcgacgtcgagggcgcggccctgcagcgtcacggcgaactc
ggcctgtgggcgcccctgtcgggccaggaggcctaccaggccgccgtcaccaaggtgatg
aagccccaggacatggtgttcggcacttaccgcgagcagtcgatcgccctgcagaagggc
gtgccgctgggtgacatcctggccgtgtggcgcgggtcgagcctgtcgcgctggatcgcc
agcgacgcccaggtggcgccctattacatgattatcggcgcccagccgctgcatgcggtc
ggctatgcgatgggagtggcccgcgacaaggccaagcaccccaccgacccggccaacgat
gccgtgacgctgaccatctacggcgatggtgcgtccagccagggcgatgtgaacgaggcg
ctggtctttgccgcctcgcagcaggcgccggtggtcttcctcaacgtgaacaaccagtgg
gccatcagcgagccgtccagcgtgcagacgcgcatcccgctctaccagcgggcgatgggc
ttcggcatccccggcatccgggtggacggaaacgatccgctggcctgccacgcggtgctc
aactgggccttcgacgaggtgcgttcgggttccgggccggtgctcgtggaggccgtcacc
tatcgcatgggcccccacaccaccagcgacgatcccaccaagtaccgctcgtcgcaggtc
accgaggagtggaaggccaaggacccgatcgagcgcctgcggagttatctgctggagcgc
ggcctgatcgactatgcgtggaccgagaagctcaacgccgacctcgacaccttcggtgcg
ctggtgcgcgacacctgtcgggcgctgccgaacaccccgatgtcggaggtcttcgacgcc
gtcaccgcggatccgggtctctatctgagcgagcagcgggccgactgcctcgactggctc
gccaccccgcccagcgaaggagcagcagaatga
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