Pseudopodoces humilis (Tibetan ground-tit): 102102026
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Entry
102102026 CDS
T02921
Symbol
OBSCN
Name
(RefSeq) obscurin isoform X1
KO
K17531
obscurin-RhoGEF [EC:
2.7.11.1
]
Organism
phi
Pseudopodoces humilis (Tibetan ground-tit)
Pathway
phi04820
Cytoskeleton in muscle cells
Brite
KEGG Orthology (KO) [BR:
phi00001
]
09140 Cellular Processes
09142 Cell motility
04820 Cytoskeleton in muscle cells
102102026 (OBSCN)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
phi01001
]
102102026 (OBSCN)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
phi04131
]
102102026 (OBSCN)
Enzymes [BR:
phi01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102102026 (OBSCN)
Protein kinases [BR:
phi01001
]
Serine/threonine kinases: CAMK group
Trio family [OT]
102102026 (OBSCN)
Membrane trafficking [BR:
phi04131
]
Others
Rho GTPase associated proteins
Rho guanine nucleotide exchange factors (GEFs)
102102026 (OBSCN)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
I-set
Ig_3
ig
Ig_2
V-set
Pkinase
Ig_5
PK_Tyr_Ser-Thr
Izumo-Ig
Ig_4
V-set_CD47
Ig_6
fn3
SOS1_NGEF_PH
C1-set
RhoGEF
C2-set_2
Receptor_2B4
FN3_DSCAM-DSCAML_C
Adeno_E3_CR1
PH
ABC1
IQ
SH3_2
RHG20_PH
IQ_SEC7_PH
Pur_ac_phosph_N
Motif
Other DBs
NCBI-GeneID:
102102026
NCBI-ProteinID:
XP_014112209
LinkDB
All DBs
Position
Unknown
AA seq
9797 aa
AA seq
DB search
MDYSSLSGVPRFLTRPKAFMVSVGKDATLSCQIVGNPIPVVSWEKDKLPVQSGGRFKTTE
DGDLYRLTIYDLSLEDSGQYICRAKNTIGEAFAAVSIKVGEETTVTESAPYFIQKPSNIK
VTLGEDAMFKCKVQGSPPLSVNWEKDGRYLRNKADAGRFQIESAGESNALTIQCAQLGDS
GTYTCRAENLIGSASASAALVVETHGSSNPGSGSNLDSSCGKTASLLSHLQKRREEIRKM
DVSHGTLDSSSAQSYSAVEGLSGIGYSLSRDYERAAGLTKGARNATFGALTRMCSVTEGK
HAKLSCYVTGEPKPVIVWKKDNEVILEGRRHVIYEDDQENFVLKILFCKQTDNGLYTCTA
SNLAGQTYSSVLVTVKEPTIPFKAKLKDLEVREKESATFQCEVPVPGTETAWFKEETKLQ
QSKKYNIEEEGTYRRLTVQNVTTDDDAVYICEMKEGSRTIAELSVQGNIIKKLPRKTAVF
INDTATFCVELDNDCQNIRWLKNKEEVKPSDRISITRSGKQHTMTIRECKMEDAGEIAFL
ADESRTSTQFTVTTPKKPPTQPPADPVMKNKTETSVTLAWSPPRMDRPIPVDGYIVERKK
LTGFTWVRCHESHVPGPELTVSNLPEEADYQFRVSAVNAYGQSPYLEFPGSLHLEPVLAV
KNPLTTAEVAPGGDALFTVDLTKTCSGTWYLNGKVLQESETHIINRTHTTHTLVIKNVTK
KDDGAEVKFVAGDVETSTKMRVRGAAVRFTNKSKDVEKVSTRLREEAKLLAELSDTEVTV
KWMKDGKELKASEKYEFQTVGKRHILKIRSAAEEDAGVYECVCEGDKMLYQLSVKAPANF
VNKEKTGGIVKAIAGKQAEFVSETSEANIMVKWYKNGKEITASKKFTMEDKGKLHKLVAS
SVTKEDEGTYTCKIGDDTLTFDLKVSDEAVTFVNKPKTTPEVSVSPSESLELVCEVSAAG
GAVVWRKDQTEVKQDQRTTIVCQGTQRKLIIKKVTQQDQGSYTCETKDDRTTFQVKVRET
EAVFTNKEKVKKEVKAALSEDATLSCEVAQEKTEVKWYKDGKLITSSKKFKVECEGKSRR
LVVGQVEKKDAGEYTCEAAGQKLTFRIDVTEAEDAFINKEKVKKEVKAALSENATLSCEV
AQEKTEVKWYKDGKLITSSKKFKVECEGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFRID
VTEAEDAFLKKEKVQKEVKAALSEDATLSCEVAQEKTEVKWYKDGKLITSSKKFKVECEG
KSRRLVVGQVEKKDAGEYTCEAAGQKLTFRIDVTEAEDAFLKKEKVQKEVKAALSENATL
SCEVAQEKTEVKWYKDGKLITSSKKFKVECEGKSRRLVVGQVEKKDAGEYTCEAAGQKLT
FRIDVTEPEVVFTNKEKVQKEVKAALSEDATLSCEVAQEKTEVKWYKDGKLITSSKKFKV
ECEGKSRRLVVGQVEKKDAGEYTCEAAGQKLTFRIDVTEPKPAFINQEKVQKEVKAVLTE
SATLVCEVAQDTTEVKWYKDGKLLVSSRKFKIETVGKSRRLVVEQLEKKDAGEYICEAAG
QKLTFKLEPTEPEAKFENKVVQKEPLVVQEHESITLTTSVTPETSAVRWFKDGTEIKASK
KCVIKSEGASRTLTVNAAESTDSALYTCQTKDDKQEFRVQVKEIPVKFARKLEAVKAEIG
GSVSLSCELSHAKGKVTWSRNGVEIKPSKRFQIREEGIKRTLTITGIRAEDEGEYSCESR
DDKSSITIVPKPPRVVKFVTSLNSVVSEEGKEAVFKCTVSPSDAVVTWLRNGAKIEASKK
YMISQKDTNHSLTITDLTLEDAAEITANAEGVKSTANLRVREASISFKKKLEPKTVEERE
TVTLEVELTKPAEVKWMRNSIVLKPSDKIEVKAEGTKHTLVVKDISFADRGFYCCESPDD
KTQAKINVEMRQIKLVKGLQPQEVAEKGTVTFEVEVSHEDVEGTWQKDGVRLKPAPNISF
GVLGKKHSLTLSSVALEDAGLISFRAEGISSSGRLTVTELPVRISKPLADVNVTQKLKAT
FECELSKPNAYVKWFKDGKEIQQSKNIGIISQGNKRSLIIHKCEYEDQGTYTCQAAEDKT
SATLKVHARDIKIVKPLEDVEVNEYESASFICEISHDEVETQWYKNDNKLKTSDNIKMRQ
DGKSYSLTYTRVHVEDAAEIRFVAEKAESRAQLTVKELPVKIVKPLRDKIALWKHRGFLE
CQVSRANAKVRWFKKDVEIHPGEKYEIVSEGVYRKLIINDADYGDEDTYTCDAFDDKTTA
NFFVEEQAINIVKELCDEDVTEPEEANFECETSIPSVKPAKWFLKGAALQAGRNVIMQQE
GTIHRLTIIKTSVDMTGTIQFSIGKSKSTANLLVRDYHIQITRKLEDKTVLERHSVILSC
DFRPSPKHVKWFKGQVLIEPSEKYKIKRDQYSAELKIMKVKPEDAGVYKCRAGIAETEAT
LSVEARNVEVLKHLQDVEIEEDSSAVFSCELSHDDEDVEWFLNGTLLYTNNFNDIKSVGK
CYMLTMKQVKPEDAGTVTMKSDKVSETVRLKVIEKPAVFMKSLDDVFGEERGVIKLECEV
SKEKVKPVWKKDGVKITSSKKYEETQSGKTLCLIIHDLEKTDAGLYTCDIGTDVAKSKVS
VQELNIGITKRLKNTEIQEGEDCTFECILSHESIDDFNWTLNGRKVESGGRFKASNAGRK
YTLSIKNVIPDDTGEVIFTARGLTSKASLVVKEKPTEVTKQLEDKTSPAGQDISLSCELS
KADVNIRWYKDGKAIRKSQKYELQQEGTLATLIIRESTVKDSGEYTCETETSKTTARITV
QEKPNYFVKELSDLKVDESGTAVFVCQSERAASSVIWRKGMAELRAGRKYEITQKGQVLQ
LTIKNLEKSDSDTYTCDIGDSQSRAKLTVQGQKVLITEDLEDVTVLEGESAKFKCRISPV
DYSRVQWFLDKTPLHTNELNEIQSQPGGYHLLTLKKLSLKDSGVITFEAGDKKTSASLVV
KETPVLFKQELQNEEAKEGKQVRLTCELSKPGTPVKWMKGDTVLCASEKYKFKQQGTVAE
LIIRDVKSVDAGDYTCSAGELKTTAQVKVNAVPVLFKQALENMDMEEGKSVSLCCELTKA
DATVVWKKGEAMLQASAKYEMKQKGTVAELVIHNAEPEDAGRYTCDTGDQQTTAQVKIHA
VSVLFKEELKPVEAVEGGTATLRCQLGTEAPVEWRKGQTLLRASSKYKMRQEGTVAELLI
HDLEPKDAGDYSCLVGNQKTTAALSVNAPPVRFKQELRNEEATESGTATLQCELSRPGGS
IQWRKDGKVLIPNGKYKMRREGRFVELVIQDLDLTDAGSYTCVCGEQESTAALRVNALPI
LFQEELMNEEATEGEAVTLHCKLSKSAPVEWKKGTMVLKPSEKYKIEQEGPIVELTIQDL
DLGDAGDYSCVCGDRQTTAALAVNVLPALFTKGLMDKEATEGKSVSLHCELNKAAANVEW
RKGLKTLKPSEKYKMKREGVVAELIIQNLGTADTGNYSCVCGDQQTMAVLTVHALPAFFK
EGLKNREATDGSTATLRCELSKVGVPVEWKKGEKALKPSEKYRMRQEDTAAELLIRDLEV
EDTGEYTCVCGDQKTSAVLTVHALPAQFKRDLVNVEGTENRTAVLQCELSKPAPVEWRRG
QEVLRPSEKYKMRLKDTTAELTIHSLEEGDAGDYTCVCGDKTTTASLTVHALPPHFKKEL
KNVEGTENGTATFCCELSKAGAAVAWRKGDKTLGISDKFTMRCQGTMAELLIRDLVLADA
GDYTCSCGEQETTAALKVNALPVHFQKEMRDEEATEGATATLQCELSRAASVEWRKKHKV
LKPSEKYTMRQEGTSAQLLIHALEVRDAGEYTCVCGEEKTTAALTVHALPALFKEELRDE
EAKEGEAVTLRCELTKPAPVEWKKGHTALKPSEKYKMRQKDVTAELVIHSLTESDAGDYT
CVCGEEQSTASLAVHVLPAGIQESLKDQEVTEGQVATLRCELTKAAPVEWRKGSTLLKAS
DKYKMRQEGTVRKLLIQDVELKDAGEYTCVCAEQETTAALIVHALPALFKEDLKDLQAVE
SQTATLRCELSKAAAVTWRKGNKILRAGAKYIMRQEGALAELEIRDLELQDAGDYTCVCG
DQHSTASLTVKALPVLFKGELKDEEAQEGASVTLRCELTKGAPVQWKFGPKVLKASDKYQ
MRQSGLTAELVIRDLEVKDAGGYTCVCGDQKTTATLSVHALPAVFKEELKDKEAEEGGEV
SLLCQLSKAAPVEWWKDQRLLKPSGKYKMRQEGLKAELVIHEIAEEDAGDYTCVCGEHQT
TAVLTVQALPPFFQEEMASQEGVEGGMATLRCQLSKAPARVQWKKGQHILTSGTKYSMRQ
EGCAVELLVHGLDLSDSGDYSCVCGDKTSTAALTVHVLPPEFKRELKDLEAVENGTAALQ
CELTKPAEVEWKKGQEVLKDSRKYEMSQDGAVAKLVIHELEEEDAGVYTCVCGDQQTTAT
LTVNALPALFKQELQDTEAEESGTVTLRCELTKPKAPVEWRKGDVTLYPGLKYEMRQQGC
AAELVIYDLELDDSGIYTCDSGHQRTTAVVAVHALPITFKQPLQNKEFEEGSTATFCCEL
SKPSAAVEWRKGGVGLQPSQKYEMRQRGCLVELLIHNLRLEDTGEYSCDTGDQETRAALN
VKALPVLFQKQLKDEEAEEGAAVKFQCELTKDNAAVEWRKGTMELFPCAKYEIKLSGHTA
ELVIHNVEPEDASDYTCDTGDQQSTAVLRVNAIKPQLKQQLRNEEVEVGGTARLRCEISI
SKAEVEWRKDGVLLHSSSKYEMWQDGTLRELRVHHLEPGDAGEYSCKAGDQTSSAKLTVK
EPDVTIVSGLRDTVVSEGDDVTFRCQVSHENARDVEWKLQDVALQNNEMNEISVEKGKIH
TLTLRKVTEQDIGTVTFRVGPHTSTAELRVKASPVTFTQPLQNQQAEEGSSVTLSCEVSK
SNTTVQWKKAGTVLRPSDKYKMRQEGSVAELTIHNLSEADAGEYTCDTGDQQTTAAVHLK
EPAATIVERLKDVATYEGEDAVFECRLSRETAQGAQWFLGDVPLQSNEMNEIRVQGTRHS
LILRKVTLEDCGSISFKVGQHSSAAQLKVEAAPVTFVKALHNLELQEGGTAHLSCEVSKP
DVPVEWKKGTSVIHSSHKCSIQQEGKVHTLVIRDLNRADSGEYSCHTAAGKTTARLEVKG
LPVLFKQWLKNEEVEEGRTAVLRCELTQPHARLEWRKGDTVLQPGDKYEIRQEGTRAELL
IYEAEAQDAGEYTCDSGDQQTTASLQVKVLPVLFNKELKNVETEEGGTAVLHCEISKPDA
PVEWRKGGVVIQPSDKYEVQLKGSVAELIIHGVEPDDCGDYTCSTGYEITTGSVYVQEEA
AEIVSGLRNTDVFVGESATFSCELSHPGVKNVQWWLDGTPLHNNLVTEISEQDGRIHTLT
LNDVACHDSGTVTFRAGSLISSAKLLVKDPTIEVVSPMQDITVDEDGPAEFICQYSRPVH
AIWKKNDQEIHADGQRVIIDQDWNVSMLKINPTVPEDTGIYSCEAEGIKVMATLDVQAKN
SIVQGLENVEAVEGGEALFECYLSKPETYNYNWLIDDEPAKTTENTEMVYFENGLRHILL
LKNLTPQDSCRVTFMCSDAVTSAFLTVKGWRLQFLQPLTDVEVSLGQKATFSCVLSEAVP
VNEVAWYSNDTEIQSGEDWEVQADGNKYKLILKKAQLHHSGEVTFASREAISSAKLSVIA
LPEPPEEPEVLSQSSHSVTLSWHKPLGDGGRDILGYKVERKIAGVGWQSCSEGLIQNTEL
TVDGLAPGEPYRFRVSAVNKAGASEAVHFPQMVRLEPPVTVTQPLVGGSVSEGGVARLEC
TLSSKTQEKVTWFKGKEQIKAGGKYEILSDGTKQILIIHGFKPEDQDSYTCMASPEVKSV
ASLCLEVPTVSMLKEIAREPPPVSRAEELVDGHIQPSLPPEAAQEGDLHLLWEALAKKRR
MSREPTLDSISEVPEEDEKLQKLRKEEAEMSHYYSEEYSTCDELARTGEADFSFTSSDDE
SRAGTPSLVNYLKKAGKKTISVTSKVQSTSTEKLWKQWETSTVETTVATTAAQPAEPELP
DLNDPSMNKAAVKIQAAFKGYKVRKEIKQQECPVFTETFKDFSGEPGSTLHLECVAHSKT
DMNVRWLKDGKELSDGRYYHIDSYSDGTCSLIIAGLDRKDAGKYTCEASNKFGKVSHSAK
VVVGTQEPQVLPKEKRSKQSTDSETESSSGSELDDAFRKAGRRLHRLFRAKISTEISDVE
EELFVSADEGDIDVVDHQTYREDDQYIYIKFEIMSEAKSAATRFREMFGALGIPVEISIL
EQGPKKIELRIGKASPPTFGKFAPPVARPPPPLLTSDSAPMFMTELQNQEVQDGYPVSFD
CIVIGKPLPTVRWFKDGKAIEENDHYMINEDQEGCHQLIITAVVPTDMGVYRCLAENSMG
VASTKAELRVDLTSTDYETAADATETSSYYSAKEYISSREQEESTTEEEQLPQIFDELHD
IHVAPGASLAKFHLKVKGYPQPRLYWFKNGQPLKASDRILKTDRQEFHSLEIRDVTKADA
GQYLIFVINSAGSAYSSARLVVKDPYEKEEPSKTDSHEQLTPPRFLERFTNKKVKKGASI
TLSVKVEGHPPPTITWMKEESREDILWIKPDTPGYKLASSNMHHSLILLDVKKKYSGAYT
CIATNQAGQSICTASLEVADVKEAEVLTQERVMVSEAIMTTLGTIQSSEGDLEAGREGVP
KSPISLADVGSEEFFQKLTSRISEMVSAKITQAKLRVPGAESDDESRTPSASPRHGRSRP
SSIAQESSSESEDGDSRGEIFDVYMVTADYVPAAPDKETITLKEGQYVEVLDSAHPLKWL
VRTKPTKSSPSRQGWVSPAYLDKKLKLSPEWGTMEIPEFPGEFVSEDEYKRKLSVLIQEL
LISEEDYIQDLQFLQTHHLRYTETCPSVPGAVASQKSTIFRNIDDIGRFHSSVFLRSLQG
CDTDDDVAMCFIKHEAEFNKYIQYLVGRVQAESIVVSKAVQDFYKRYTDEFVTNEDPSQP
LIPPLQHYLEKPINRIQQYQTIIKELIRNKARNSQNCTLLEQAYAIVSALTRRAENNLHV
SLIENYPGTLESLGEPIRQGHFIVWEGAPGARMAWKGHKRHVFLFKNYIVICKPKRDTKT
DTYSYIFKNIMKLNNIDVNDLVEGDDRAFEIWHEREDLVRKYLLQARTVNIKNSWVKEIL
GIQQRISEPIWIPPDFEEELADCTAELGETVKLACKVTGAPKPSISWYKDGKPVEVDPHH
IIIEDPDGSCTLILDNLTGADTGQYMCFASSPAGNASTLGKILVQVPPRFVNKVRNAYLV
EGEDVQFTCTVEGAPRPQIRWYKDGVLLKDTGKYQTFSEPRSGIVVLVVKNPSNEDMGHY
ECELMNRLGSAKSGAELYHHSAAALTQERRGDQAITIEGMTSPQSETETSVQASLQRADK
EIKTALKKLMDSASLLVTLPPGMRADGGFGLGPPGPVPSEHSGAAAGPSVVVHEASTQTQ
AAGDHAKAQRQVPAEEPGVPKPSPAPSREEEAAGGASARERTVPIDRTSPDAGAGGWYRR
EGDVVVHSEVYIETTERTRVYKTEEKTPTSPPYMQVTIEDVQVNSGECAKFQAVIEGTPQ
PTVLWFKGTSLLMDSDRVHQGKEGTTYFLVVDNAALEDGGVYTCVAKNAGGEVLCKAELV
VREAKKDQEGKKVATRRKLHSHYEVKQEIGRGCFSFVKRVVHKGNRVSCAAKFIPLRSKT
KSRAHQERDILASLSHDRITRLLDEFETRKTLILILELCSSEELLDRLFKKNVVTEAEVK
LYIKQILEGIKYLHDNNILHLDVKPLNILMVYPEREDLKICDFGFAQRITPVEPQYSKYG
SPEFVAPEIVSQSPVSKATDIWAVGVITYLSLTCKSPFAGENDRKTLLNIQNGEISWTIP
DVVHLSEDAKDFMKGILQQHPKSRPSALDCLSHKWFMHNVPLEAAHFINTKQLKFIVARS
KWQRSLMCYKSILVMRSIPEILERTHDNSSLAISRHLIEESTSSSTSGSSSDNENSNFPK
KRHFGSTPELHLPVFDVPGHPEPLKCASERELAKSSIPPVKPMRRKYASMKAEVGDKSPT
ESKELMASILQEKEERLLPSLRGEPSQKGGTAEPSSLRASTESTSLLHQKEKPDTSLSEK
DRTEEAGDGTEKPSACVPRQSVIKSTFYSQATELPARPPSSPGREFRRHLDRARRTFRKG
GYSKVPLSGLREPLLEQFELEEEEEEGGGDDHKESLLGSLTKSASFDTARKPPHPAIAGA
SRSRSLDDYRLRTSRSLREQDILEEDCDVLSQESCPEGSDHCDISAGPGKGCSADTAEPG
DVRRASKDCSGEKPSPSTHCEGNGCPPALIQQLEGLPVSPLRSENRKRLLKKSKATEIEE
DAECLEGKSPIPTAQCSDVTAPSAPKHESTKGKSASGCASDSAFQEGKESISTLTQSETT
LRSSPPSKRGVCLPQEPAPTDSHPDLTGGSLLIKRTAPAPPWKDKRQKHSDEKTSAHGTA
GSELMEHESSAVPTEQKETDLLPVCKDKSEEIPGKSVPAATVMLGKQPGTLTSGEGVPQK
LKTPKEVRSAVLEDAEEAVPGITAPSAHSDESQTHKKAPVHSDTASAVLKGEQLRVPQIP
PPGSVPPLVSGGAQQALSKKKLAALRNKSSAFATEVVSSLAHEGAEPQEVLEGHGSDPAA
LESRHPARAVSSQCIVLPQVWESENQEHPEVSVHSEMRSVVTGSRAAGQAVAAPFPKAGH
RVFEQHRAGISDGLESGSSGALTPSQPEVAPASAYDLEYEEYPEVYGEGGGIALESGRCD
AGKAAPPLLRREHSQELSHHRSSFYSDEESAVLEGLVDEMVSLSEEMNVWAESVSGEKGS
RKHVSPHREMFYKGSQTHMDSSFPSVQQDGRGEVTEKDGLAEPYLAVSEEPGVLEEQVAQ
TVPQECEQLEDLAFETSPSSPESVSSTESLDTTKRPIHVPVIKDTGKHPEVSLVKIKDLS
DETPSPGSGPHKFDISEVEPAYLNFSDLYDIVYFPFEFLSYKKPSPKPVPRRFMLLGQRA
RSPPAGHLHKDKKLCIREQEDKNRKNQLEISEDSKAANLLAMGKGAESQKEMYSSQKDCS
GKQKSSFHTKPGLFKPYARSHSVEQSVEQSLKKKVKASVAHISRILKGKTSPEPEEEFGE
LGSEAAEKELLIGAEGSLKRKSALPSFKLPSLTPKEKAPSFVEELMDQAAAAGQCVTLSC
RTAAHSSLHISWFRDGIPVQSSSRILISSTLKHFQLLTILSVNAEDFGIYTCVATNSLGS
ASTSCVIRKTEVPPCPPPPDIVEVYKDGVQMVWKPVETNTPVHYTVQCKTEDGEWTTLAS
DITDCCYYARNLPQGFTYHFRTACTSKAGMGPYSDPSAKVKITGKDQMELRAATQELPSA
APEEESEMITPPEPFPTYQTYAFQTEIKRGRFSIVRQCREKVSGKALAAKIIPYWQEDKQ
AVLLEYQVLRKLHHTNIAQLKGAYVSPRHLVLIQEMCVGPELLHSLALRTSYSEVEVRDY
LWQILSATEYLHAHNILHLDLRSENMIITEPNLLKLLDFGNAQFYTPEKFITMDKCSDYV
ETMAPELLTEQGALPQTDIWSVGITAFIMLSANYPVSSDVPCEFLRTARKGKLKLMRCYA
GLSGGAVSFLQSTLCANPWGRPSASECLQSPWLQETGLDNRQQALVTFPTTKLRNFLMER
EKKRGLLCSKYGLMIAQ
NT seq
29394 nt
NT seq
+upstream
nt +downstream
nt
atggattacagctcgctcagcggggtcccgcgcttcctgacccggcccaaggcgtttatg
gtgtctgtagggaaggatgccaccctgagctgccagattgttggaaaccccatcccagtg
gtgagctgggagaaggataaacttccagtccagtcagggggaaggtttaaaaccacagag
gatggggatttgtatcggctaaccatctacgacctgagcctggaggacagcggtcagtac
atctgccgggccaagaacaccatcggggaggcgtttgctgctgtcagcatcaaagtggga
gaggagaccacagtcacagagtcagctccttatttcatccagaaaccttccaacatcaaa
gtgaccctgggagaagacgccatgttcaaatgcaaagtccagggcagccctcccctctcg
gtgaactgggagaaggatgggagatacctgaggaacaaggcagatgctggacgcttccag
atcgagtctgccggggagtccaatgctctcaccatccagtgtgcccagctgggggacagt
ggcacctacacctgccgggcagagaacctcatcggctccgccagcgcctcggccgcgctg
gtggtggaaacgcacggctcctccaacccgggcagcggcagcaacttggacagcagctgt
ggcaagacagcctccttgctgtcccacctgcagaagaggcgggaggagatccggaagatg
gacgtctcccatgggactctcgactcgtcctctgcccagtcttactctgcggtagagggg
ttgtccggcatcggctacagcctgtcccgagattacgagcgggcggcgggactgaccaaa
ggggcccgcaacgccactttcggggcgctgacacgcatgtgcagcgtgacggagggcaag
cacgccaagctgagctgctatgtgacgggtgagcccaagcccgtgattgtgtggaagaag
gacaacgaggtcattttggaaggccggcggcacgtcatctatgaggatgaccaggagaac
tttgtgctgaagatcctcttctgcaagcagacggacaatgggctgtacacctgcacggcc
tccaacctggcagggcagacctacagctccgtgcttgtcactgtcaaagaacccaccata
cccttcaaggcaaaactgaaggatcttgaagtgagggagaaggaatctgccaccttccag
tgtgaagtgcccgttcctgggactgagacagcttggttcaaggaggagaccaagctccag
cagagcaagaagtacaacatcgaggaggagggcacctaccgccggctcactgtccagaac
gtcaccacggatgacgatgctgtttacatctgtgagatgaaggaagggagcaggaccatt
gcagagctgtctgtccaagggaacatcattaaaaaacttccacggaaaactgctgtcttc
atcaacgacacagccaccttctgcgtggagctggacaacgactgccagaacatccggtgg
ctgaaaaacaaagaagaagtgaaacccagtgaccgaatctccatcacgcgctccggcaag
cagcacaccatgaccatccgggagtgtaagatggaagatgctggtgagatcgccttcctg
gctgatgaaagcaggacttccacccagttcactgtgaccactcccaaaaaacctcccacc
caacccccagctgaccctgtgatgaaaaataaaacagaaacctcagtgacactggcatgg
tcccctccgaggatggaccggcccattccagttgatggctacatcgtggagcgcaagaaa
ctcaccggcttcacctgggtgaggtgccacgagtcccacgtccccggccccgagctcacc
gtgagcaacctgccagaagaggctgactaccagttcagagtgtccgcggtcaacgcctac
ggacagagcccctacctggagttccctgggagcctgcacctcgaacctgtcctggctgtg
aaaaaccccctgacaacagctgaagttgcacctggaggggatgccctgttcactgttgat
ctgaccaagacatgttccggcacttggtacctgaatggcaaagtcttacaggaaagtgag
acccacatcattaacagaacccacaccactcacaccctggtcataaaaaatgtcaccaag
aaagatgatggggcagaagtgaaatttgttgccggtgacgttgagaccagcaccaagatg
agagtgagaggagctgcagtgagattcaccaacaagagcaaagacgtagaaaaagtctcc
actcggctgagggaggaagccaaactcctagctgagctttcagacacagaagtcaccgtg
aagtggatgaaagatgggaaggagctcaaggccagtgaaaaatacgagttccagactgtg
gggaagaggcacatcctgaaaatccgcagcgctgccgaggaggacgctggagtctatgag
tgtgtctgtgaaggggataaaatgctctaccagctctcagtgaaagcacctgcaaacttt
gtaaacaaagagaaaactggaggaattgtcaaggccattgctgggaaacaggctgagttt
gtgtctgagacctccgaggccaacatcatggtgaagtggtacaaaaatgggaaggaaatc
acagccagcaagaaattcaccatggaagacaaaggaaaactgcacaagcttgtggcttcg
tctgtgacaaaagaagatgaaggaacttacacctgcaaaataggggatgacacccttact
tttgatttaaaagtctcagatgaagctgttacttttgtcaacaagcccaaaacgactcca
gaagtatcagtcagtccttctgaaagcctggagctggtgtgtgaggtgtcagctgcgggc
ggggccgtggtgtggaggaaggatcagactgaggtgaagcaggaccagaggacaacaatc
gtctgccaagggacacaacgcaagctcatcatcaagaaggtgacacagcaagaccaaggc
agctacacctgtgaaacgaaggacgacagaacaacattccaagtcaaagtcagagagaca
gaggctgtgtttacaaacaaggagaaagtgaagaaagaggtgaaagctgcactgtcagaa
gatgccacgctgagctgcgaggtggcccaggagaaaacggaggtgaagtggtacaaggat
ggcaaactcatcacctccagcaagaagttcaaggtggagtgcgagggcaaatcgcgtcgc
ctggtggtgggtcaggtggagaagaaagatgctggggagtacacctgtgaggctgctggc
caaaaactcaccttcaggatcgatgtcacagaagcagaggatgcatttatcaacaaggag
aaagtgaagaaagaggtgaaagctgcactgtcagaaaatgccacgctgagctgcgaggtg
gcccaggagaaaacggaggtgaagtggtacaaggatggcaaactcatcacctccagcaag
aagttcaaggtggagtgcgagggcaaatcgcgtcgcctggtggtgggtcaggtggagaag
aaagatgctggggagtacacctgtgaggctgctggccaaaaactcaccttcaggatcgat
gtcacagaggcagaagatgctttcctcaaaaaggagaaggtgcagaaagaggtgaaagct
gcactgtcagaagatgccacgctgagctgcgaggtggcccaggagaaaacggaggtgaag
tggtacaaggatggcaaactcatcacctccagcaagaagttcaaggtggagtgcgagggc
aaatcgcgtcgcctggtggtgggtcaggtggagaagaaagatgctggggagtacacctgt
gaggctgctggccaaaaactcaccttcaggatcgatgtcacagaggcagaagatgctttc
ctcaaaaaggagaaggtgcagaaagaggtgaaagctgcactgtcagaaaatgccacgctg
agctgcgaggtggcccaggagaaaacggaggtgaagtggtacaaggatggcaaactcatc
acctccagcaagaagttcaaggtggagtgcgagggcaaatcgcgtcgcctggtggtgggt
caggtggagaagaaagatgctggggagtacacctgtgaggctgctggccaaaaactcacc
ttcaggatcgatgtcacagagccagaagttgtgtttacaaacaaggagaaggtgcagaaa
gaagtgaaagctgcactgtcagaagatgccacgctgagctgcgaggtggcccaggagaaa
acggaggtgaagtggtacaaggatggcaaactcatcacctccagcaagaagttcaaggtg
gagtgcgagggcaaatcgcgtcgcctggtggtgggtcaggtggagaagaaagatgctggg
gagtacacctgtgaggctgctggccaaaaactcaccttcaggatcgatgtcacagagccc
aaacctgcatttataaaccaggagaaggtccagaaggaggtgaaggctgtcctgacagaa
agtgccaccctcgtgtgtgaggtagcgcaggatacaactgaagtgaagtggtacaaggat
ggaaaactgctcgtttcctctcggaaattcaaaatagagaccgtgggcaagtcccggcgc
ctggtggtagagcagctggagaagaaggacgctggggaatacatctgtgaggctgcaggc
cagaagctgaccttcaaactggaaccgactgaaccagaggctaaatttgaaaataaagtt
gtccagaaagagcctctcgttgttcaagaacacgaaagcatcacactgacaacctcagtc
acgccagaaacctctgcagtgaggtggttcaaggatggcacagaaatcaaagccagcaag
aaatgtgtgatcaagagcgagggggcatccaggacgctgacagtgaacgcagccgagagc
acagactctgccctctacacctgccagacaaaggatgacaagcaggaattcagagtccag
gtgaaagaaatcccagtgaagtttgccaggaagctggaggccgtgaaagccgagattggt
ggcagcgtgtccctgagctgtgagctgagccacgccaaggggaaggtgacatggagcagg
aatggggtggagatcaagcccagcaagcgtttccagatccgtgaggagggaatcaaacga
accctgacaataacagggatccgggctgaggacgagggagaatattcctgcgagtccagg
gatgacaagagcagcatcaccatcgtccccaaacctcccagagtggtgaaatttgtcaca
agtctcaacagcgtggtgtctgaggagggaaaagaggccgtgttcaagtgcaccgtctcc
cccagtgatgccgtggtcacctggctcaggaacggggccaagattgaagccagcaagaaa
tacatgatctctcagaaggacaccaaccacagcctcaccatcactgacctgacactggaa
gatgcagctgaaatcactgccaatgctgagggtgtgaaaagcacagccaacctcagagtc
cgagaggcctcaatctccttcaagaagaagctggagcccaaaactgttgaagagagggag
acagtgaccttggaggtagagctgaccaagcctgcagaggtgaagtggatgaggaacagc
atcgtgctgaagcccagtgacaagatcgaggtcaaagctgagggaacaaaacacaccttg
gtggtcaaggacatctccttcgcagaccggggcttctactgctgtgagagccccgatgac
aagacacaagccaagatcaatgtggaaatgaggcagatcaagctggtgaaaggccttcag
ccccaggaggtggctgagaaagggactgtcaccttcgaggtggaggtgtcacacgaggac
gtggaggggacctggcagaaggatggtgttcgtctgaagcctgcacccaacatcagcttt
ggtgtcctgggcaagaagcattccctgactctctcctcggtggcactggaagatgcagga
ctcatctccttcagagcagaaggcatcagctcatcagggaggctcactgtgacagaatta
cctgtgaggatcagcaaacctctggcagacgtcaatgtaactcagaagctcaaggccaca
ttcgagtgtgagctgtccaaacccaatgcctatgtgaagtggttcaaggatgggaaggag
atccagcaaagtaaaaacattgggattatctcccaaggaaataagagaagcctcattatt
cacaagtgtgaatatgaagaccagggaacctatacatgtcaagcagctgaagacaagaca
tcagctactctaaaagttcatgcccgagatatcaagattgtaaaaccactggaagatgtg
gaagtgaatgaatacgagagtgcatcttttatctgtgagatctcacacgacgaggtcgaa
acccagtggtacaaaaatgacaacaagctgaagacttcggacaacatcaaaatgcggcag
gacggaaagagctattccctgacttacacacgtgtccacgtcgaggacgcggctgagatc
agattcgtagcagaaaaggcagaatctcgtgctcagctgaccgtaaaagagctgcctgta
aagatcgtgaagcctctgcgggataagatcgccctgtggaagcaccggggcttcctggag
tgccaggtgtcccgagccaatgccaaggtccgctggttcaagaaggacgtggaaattcac
cccggtgagaaatacgaaatcgtgagtgagggcgtctatcggaaactcatcatcaacgac
gccgactacggagacgaggacacgtacacttgtgacgccttcgatgacaaaaccactgct
aatttcttcgttgaagagcaagccattaacattgtaaaagaattgtgtgatgaggatgtg
actgagcctgaagaagccaattttgaatgtgagacatccattccatctgtgaaacctgcc
aagtggttcctgaagggagcagccttgcaggctggcagaaacgtcatcatgcagcaggaa
ggcaccatccacaggctgacaataataaaaacaagtgttgatatgacaggcaccatccag
ttctccattggcaaatccaaatccacagcgaacctgctcgtcagagattaccacatccag
atcaccaggaagctggaggacaagaccgtcctggagcgacactcagtcatcctgtcctgt
gacttcaggccttccccaaagcacgtgaagtggttcaagggccaagtgctcattgagccc
tcggagaagtacaaaatcaagcgggatcagtactcggcagagctcaagatcatgaaggta
aagcccgaggatgccggcgtgtacaagtgcagggccgggattgctgagaccgaagccacg
ctgagcgttgaagcccgcaatgtagaggtcctgaagcacctgcaggacgtggagatcgag
gaggacagttctgctgtgttctcctgcgagctgtcccacgacgacgaggacgtggagtgg
ttcctcaatggcaccctcctctacaccaacaacttcaacgacatcaagagtgttggcaag
tgctacatgctgaccatgaagcaggtgaagcctgaggatgctggcacagtgacaatgaag
tcagacaaggtgtcagagaccgtgaggctgaaggtgatagagaaacctgctgtcttcatg
aaatccttggatgacgttttcggtgaggagcgaggagtgatcaaactggaatgtgaagtc
tccaaagagaaggtcaaacctgtttggaagaaggatggtgtgaagatcacttctagcaag
aagtatgaggagacacagtctgggaagactctgtgcctcattatccatgaccttgagaag
acagatgcggggttatacacctgtgacatcggcactgatgttgccaaatcaaaggtcagc
gttcaggaactgaacattggcatcaccaaacggctcaagaacactgaaatccaggaggga
gaagattgcacttttgagtgcattttgtcccatgaaagcattgacgacttcaactggaca
ctgaatgggaggaaagtggaaagcggggggagatttaaagcctccaatgcaggtcggaaa
tacacactgagtatcaaaaatgtgattcctgatgacactggggaagtcatcttcactgcc
cgtggtctcacctccaaggcttccctggttgtgaaagaaaaacctactgaggttacaaaa
cagctggaggataaaacatcaccagcagggcaggacatcagcctgagctgtgaattgtcc
aaagctgatgtgaacatcaggtggtacaaggatggcaaagcaatccggaaaagccagaaa
tacgagctgcagcaggagggaacactggccactctcatcatccgtgaatccaccgtcaag
gacagcggggaatacacctgtgagacagaaacctccaaaacaacagccaggatcacagtg
caagaaaagcccaattattttgtcaaggaactatcagacttgaaagtcgatgaaagcgga
actgcagtttttgtgtgccagagtgagagagctgcatcctctgtcatctggaggaaaggc
atggctgagctcagggctggcaggaaatacgagatcacacagaaaggacaagtcctccag
ctgaccataaagaacctggagaaaagtgacagtgacacttacacttgtgacattggggac
tcccagtccagagccaagctaactgtgcaaggccagaaagtgctaataacagaagacctg
gaggatgtcactgtgttagaaggagaatctgccaagttcaagtgcagaatctctcccgta
gactatagcagagtgcagtggtttttggataaaaccccactccataccaatgaacttaat
gagatccagtcccagcctggtggatatcacctgctaacactgaaaaagctctcactgaag
gactcgggggtcattacatttgaagctggtgataagaaaacatctgccagtttggttgtt
aaagaaacaccagttcttttcaaacaagagctccaaaacgaagaagccaaagaaggaaag
caggtcaggctgacctgtgagctcagcaaacctggtaccccggtgaagtggatgaaggga
gacactgttctctgtgccagtgagaagtacaaatttaagcagcaagggactgtggcagag
ctcataattcgagatgtgaaatctgtagatgctggggactacacctgcagtgctggggaa
ctgaaaaccactgctcaggtcaaagtgaatgctgtgcctgtccttttcaaacaagccctg
gagaacatggatatggaagaagggaaatccgtctccttgtgctgtgaactcacaaaagct
gatgccaccgtggtgtggaagaagggagaagcaatgctccaggcaagtgccaaatatgaa
atgaagcagaaggggacagtggcagagctggtgattcataatgcagagccagaagatgcg
ggaagatacacctgtgacactggagaccagcagaccacagcccaagtcaaaatccatgct
gtgtccgtgctcttcaaggaagagctgaagcctgtggaagctgtggaaggtgggacagcc
accctgcggtgccagctgggcacagaggcccctgtggagtggaggaaggggcaaactctt
ctccgggcgagtagcaagtacaagatgaggcaggagggcaccgtggccgagctgctgatc
catgacctggagccaaaggatgctggagactattcatgtctagtggggaaccaaaaaacc
acagcagccttgtcagtgaatgccccgccagtccgtttcaagcaagagctgaggaacgag
gaggccacggagagcgggacagcgacgctgcaatgcgagctgagccggccaggaggctcc
atccagtggaggaaggacgggaaggtgctgatcccaaacgggaaatacaaaatgaggcgg
gaaggacgctttgttgagctggttatccaagacctggacctgacagatgctgggagctac
acctgcgtgtgtggagagcaggagagcacagctgctttgagagtgaatgccttgcctatc
ctcttccaagaagaattgatgaacgaggaagctacagagggggaggcagtcactctgcac
tgcaaactgagcaaatcagccccagttgagtggaaaaaggggactatggtgctcaagcca
agtgaaaagtacaaaatagagcaggaaggtcccattgtggagctgacaatccaggatttg
gatttgggagacgctggggattacagctgtgtgtgtggagaccgacagactacagctgct
ctggcagtaaatgtcctgcctgctcttttcaccaagggactcatggacaaagaagccacc
gagggtaaaagtgtctccctgcactgcgagctgaacaaggctgctgctaacgtggagtgg
aggaaggggctcaagaccctcaagccaagtgaaaaatacaaaatgaagcgggaaggtgtc
gtggctgagcttataatccaaaatctaggcacggcggatactgggaattattcctgtgtg
tgtggagaccagcagaccatggcagttttaacagttcatgctttgcctgcatttttcaag
gaagggttgaagaacagggaagccacggacggttcaacagccactctgcgctgcgagctg
agcaaggtcggcgtcccagtggagtggaaaaaaggggaaaaggcactcaaaccaagtgaa
aagtacaggatgagacaggaagatacagctgcagagctgctgatccgagatctggaggtg
gaagatacgggagaatacacctgtgtatgtggagatcagaagacctcggctgtcttgaca
gtccatgctctgcctgcacagttcaaaagggatcttgtcaatgtggaaggcacagaaaac
aggacggcagttctgcagtgtgagctgagcaaacccgccccggtggagtggaggaggggg
caggaggtgctcagacctagtgaaaaatacaaaatgaggctgaaggacaccactgctgag
ctgacaatccacagcctggaggaaggagatgcaggagattacacctgtgtgtgtggagac
aagaccaccacagcttccttgacagtgcatgccctccctccccactttaagaaagagctg
aagaacgtggaaggcacagaaaatggcacggccactttctgctgtgagctgagcaaagct
ggagctgccgtggcgtggaggaaaggagacaaaaccctggggataagtgacaagttcacc
atgagatgccagggcacgatggctgagctgctgatccgggatttggtcctggcagatgct
ggagattacacatgctcttgtggagagcaggaaaccacggccgcgctcaaagtgaatgcc
ctgcctgtgcacttccagaaggagatgagggatgaagaagccacagaaggtgcaacagcc
actctccagtgtgagctgtccagggctgcctccgtggagtggagaaagaaacacaaagtg
ctcaaaccgagtgaaaaatacacaatgaggcaggagggcacctcagcccagctgctgatc
catgctctggaggtcagggatgctggggaatacacctgtgtgtgtggtgaggagaagaca
acggcggcactgacagtgcacgcccttcctgctctgttcaaagaagagttaagagatgag
gaggccaaggagggtgaagcagtcactctgcgctgtgagctgaccaaacctgccccagtg
gagtggaaaaagggacacacagccctcaaacccagcgagaaatacaaaatgaggcagaag
gatgtcactgcagagctggtgatccacagcctgacggagagcgatgctggggattacacc
tgtgtgtgtggggaggagcagtccacagcctccttggcagtacatgtgctgcctgcagga
atccaggagagcctgaaggaccaggaggtgaccgagggccaggtggccactctgaggtgt
gagctgaccaaagctgcccccgtggagtggaggaagggcagcactttgctcaaagccagt
gacaagtacaaaatgaggcaggagggcacggtcaggaagctgcttatccaggatgtggaa
ctgaaagatgctggagagtacacgtgtgtgtgtgcagagcaggagacaacagcagccttg
atagtgcatgccctgccagcccttttcaaagaagacctgaaggacctgcaagccgtggaa
agccaaacagccactctgcgctgtgagctgagcaaggctgcagctgtgacgtggaggaaa
gggaacaaaatactcagggcaggtgcaaaatacatcatgaggcaggagggtgccctggca
gagctggaaatccgtgacctagagctgcaggatgcaggagattacacctgtgtgtgtggg
gaccagcacagcactgcctctctgacagtgaaggccctgccagtgcttttcaagggagag
ctgaaggatgaagaagcccaagagggagcatcagtcactctgagatgtgaattaaccaaa
ggagctcccgtgcagtggaaattcgggcccaaagtgctcaaagcaagtgacaaatatcaa
atgagacagtctggcctcactgcagagctggtcattcgtgacctagaagtaaaagatgct
ggaggttacacctgtgtgtgtggtgaccagaagacaacagcaaccttatcagttcatgct
ctgccagcagtctttaaggaagagctgaaggacaaggaggcagaagaaggtggagaagtc
tccctgctctgtcagctctccaaagctgctccagtggagtggtggaaggaccagaggctc
ctcaaaccaagtgggaaatacaaaatgaggcaggaagggctgaaggcagagctggtgatc
catgaaatagctgaggaggatgcaggagactacacctgtgtgtgtggagagcaccagact
acggctgtcttgacagtacaggctctgcccccgtttttccaagaagaaatggccagccag
gaaggggtagaaggtggaatggccactttgcgctgccagctgagcaaggcccctgcccgt
gtgcagtggaagaagggccagcacatcctcacctcgggcaccaagtacagcatgaggcag
gagggatgtgctgtggagctgctggtccatggcttggacctgagtgacagtggggattat
tcctgtgtgtgtggagacaagaccagcacagctgccttaacagttcatgtgctgcctcca
gaattcaagagagagctgaaggacctggaagctgtggaaaacggcacagctgctctgcag
tgtgagctgacaaaacctgctgaggtggagtggaagaaagggcaggaggtgctcaaagac
agcagaaaatatgaaatgagtcaggatggtgctgttgcaaagctggttatccatgagctg
gaggaggaggatgctggagtttacacctgtgtgtgtggagatcagcagacaactgccacc
ctgacagtcaatgccctcccagcccttttcaagcaagagcttcaggacaccgaggcagaa
gaaagtggcacagtgacactgaggtgtgagctcaccaaacccaaggccccggtggagtgg
aggaaaggggatgtgaccctgtaccctggtctgaaatacgagatgaggcagcagggctgt
gctgctgaactggtcatttatgacctggagctggacgattcaggaatttacacctgtgac
tccggacaccagcggacaacggctgtggtggccgtgcatgcactgcccatcacgtttaag
caacctttacaaaataaggagtttgaggaaggaagcacagccacgttctgctgtgagctg
tcgaaacccagtgctgcagtggaatggaggaaaggaggcgtggggctgcagcccagccag
aaatatgaaatgaggcagaggggatgcctggtagagctcttgatacacaatctcagatta
gaagacacaggagaatacagctgtgacacaggagatcaggaaaccagggcagctctgaat
gtgaaagctctgccagttcttttccaaaagcagctcaaagacgaggaggcagaagaagga
gccgcggtgaaattccagtgtgagctgacaaaggataacgcggctgtggagtggaggaaa
ggcaccatggagctcttcccgtgtgctaaatatgaaattaaattaagtgggcacacagct
gagctcgtgatccacaatgtagagccagaggatgcctctgattacacttgtgacacggga
gaccagcagagcactgcagtcctcagagtgaatgccatcaaaccccagctgaagcagcag
ctgaggaacgaggaagtggaagtgggaggaacggccaggctgcgctgcgagatttccatc
agcaaagcagaagtggagtggaggaaggatggagtcctcctgcactccagctccaagtat
gaaatgtggcaggatgggaccctccgggagctccgtgttcaccacctggagcctggggat
gctggagaatattcctgcaaggctggagaccagacgagctctgccaaactcaccgtgaaa
gagcctgatgtgaccatcgtgagcggcctcagggacacggtggtgtctgaaggggacgat
gtcacctttcggtgccaggtttcccacgagaacgccagggatgtcgagtggaagctgcag
gatgtggctctgcagaacaacgaaatgaacgagatctcggtggaaaaggggaagatccac
accctgacgctgaggaaggtgactgagcaggacattggcactgtcaccttccgggtggga
ccccacacgtcgacagcagagctcagggtgaaagcctctccagtcaccttcacacaacca
ctccagaaccaacaagctgaggaaggcagcagtgtcactttgagctgcgaggtctccaaa
tccaacaccaccgtgcagtggaagaaggcagggacagtgctgagacccagtgacaaatac
aagatgcgtcaggagggctccgtggctgagctgacaattcacaacctgagcgaagctgat
gctggggagtacacctgtgacacaggggaccagcaaaccacagcagcagtgcacctgaaa
gaaccagcagccaccatcgtggagaggctgaaggacgtcgccacgtacgaaggagaagac
gcggtgttcgagtgcaggctgtcccgggaaacggctcagggtgcccagtggttcctgggg
gatgttcccctgcaatccaacgaaatgaatgagatcagagtgcaaggcacacgccacagt
ttgatcctgaggaaggtgaccctggaagactgtgggtccatcagtttcaaagtggggcag
cattcatcagcagcacagctgaaggtggaagctgccccggtcacctttgtgaaggcactg
cacaacctggagctgcaggaggggggcactgcccacctgtcctgcgaggtgtccaagcct
gatgtccccgtggagtggaagaagggcacgtccgtgatccactccagccacaagtgcagc
atccagcaggaggggaaggtgcacacgctggtcatccgcgacctgaaccgcgccgactcc
ggggaatacagctgccacacggctgctggcaagaccacggccagactggaggtcaaaggc
ctgcctgtgctgttcaagcagtggctgaagaatgaggaggtggaggaagggcgcacggcc
gtgctgcgctgtgagctcacgcagccccatgcgcgcctggagtggcggaaaggggacacg
gtgctgcagcccggggacaagtacgagatccgccaggaggggacacgagccgagctcctc
atctacgaggctgaggctcaggatgctggagaatacacctgtgactcaggggatcaacaa
accacggcttcgctgcaggtcaaagtactgccagtgctgtttaacaaagagctgaaaaac
gtagagactgaagaagggggaacggcagttttgcactgtgagatctccaagcccgacgct
cccgttgagtggaggaaaggaggggtggtcattcagcccagtgacaagtacgaggtgcag
ctgaagggcagcgtagctgagctgatcatccatggtgtagagcctgatgactgtggggat
tatacctgcagcactggatacgagatcaccacagggtctgtgtatgtgcaagaagaagca
gcagagatagtgtctggtttaaggaacacagatgtctttgtgggcgagtcagccacgttc
tcctgcgagctctcgcacccgggcgtgaagaacgtgcagtggtggctggatgggaccccc
cttcacaacaacctggtgactgaaatctctgagcaggacggcaggatccacactttaacc
ctaaatgacgtggcgtgccatgactcgggcactgtcaccttcagagctgggtcccttatt
tcttcagctaaattattagtcaaagatcccaccattgaagtggtcagtcccatgcaggac
ataacagttgatgaagatggcccagcagagttcatatgccaatattctaggccagtgcac
gccatctggaagaaaaatgatcaggaaatacatgcagatgggcagcgagtgattatcgat
caggactggaatgtgagcatgctaaaaattaaccccacggtcccagaagacactggcatc
tattcttgtgaagctgaaggcattaaagtgatggctacacttgatgttcaagccaagaac
agcattgtgcagggcttggagaacgtggaggctgtggaaggaggggaagccctgtttgag
tgttatctctccaagcctgagacctacaattacaactggctgattgatgatgaacctgcc
aaaaccacagagaacactgagatggtttactttgaaaatgggctcaggcatatcctgctg
ctgaagaatttaactccccaggacagctgcagggtgactttcatgtgcagcgatgcggtg
acctcagccttcctcacagtgaaagggtggcgcctgcagttcttgcagcccctcacggat
gtggaagtgtctctggggcaaaaagcaacatttagctgtgtcctgagtgaagctgtgcca
gttaacgaagtggcctggtacagtaatgacacagagatccagtcgggtgaggactgggag
gtacaagcagatggaaacaaatacaaactcattctgaaaaaagcccaactgcatcattct
ggagaggtgacctttgcttccagggaggccatttcatcagccaagctttctgtgatagcc
ctccccgagccccccgaagagccagaagttctcagtcagagcagccactctgtcactctg
tcttggcacaaaccgctgggtgacggcggccgggacatcctgggctacaaggtggagagg
aaaatcgcgggcgttggctggcagtcctgcagcgagggcctcatccagaacacggagctc
accgtggatggcctggctccgggggaaccctacagattccgagtgtcagccgtaaataaa
gctggggccagcgaggcggtgcacttcccccagatggtgcggttagagcctccagttaca
gtcacccaacctttggtgggaggatctgtctcagaagggggagtggctcgcctggagtgc
acactgtcaagtaaaacccaggagaaagtgacttggttcaagggaaaagaacaaataaaa
gctggagggaagtacgagatcctgtctgatggaacgaagcagatactcattatccatgga
tttaaacctgaggatcaggacagctacacctgcatggcttctccagaagtcaaatctgtt
gccagcctgtgtcttgaagttcccacagtgtcgatgctgaaggagattgccagggaacct
ccccctgtcagccgggctgaggagctggtggatggacacatccagcccagcctgccccct
gaagctgcccaggagggagatcttcacctcctgtgggaagccctggccaagaaacgccgt
atgagccgggagcccaccttggattccatcagcgaggtgcctgaggaggatgagaagctt
cagaagctgaggaaggaggaagcagagatgtctcactactactcagaggagtactccacg
tgtgacgagctggcccggacaggagaggcagatttctctttcacaagctctgatgatgag
tctagagctgggactccttccctagtaaactacctcaagaaagctgggaagaagaccatc
agtgttaccagcaaggttcagtccacctccacagaaaaattatggaaacagtgggagaca
tccactgtggagaccactgtggccaccacggctgctcagccagctgaaccagagcttcca
gatttaaatgatccctccatgaacaaggcggctgtgaagatccaagctgctttcaaaggc
tacaaagtcagaaaagagatcaagcagcaggagtgcccagtgtttactgagaccttcaaa
gacttctctggagagcctggaagcaccctgcacctggagtgtgtggcccacagcaaaacc
gacatgaacgtccggtggctgaaggatgggaaggagctctcggatggtcgttactaccac
atagacagctacagtgacggcacctgctccttgattatcgctggcctggacaggaaggat
gccggtaaatacacctgcgaggcatccaataagttcggcaaggtctcacacagcgcaaag
gtggtggttggcactcaggaacctcaagttcttcctaaggagaagaggagtaagcagagc
actgacagcgagacagagagctcgtctggcagcgagctggacgatgctttccgaaaagca
ggaaggaggctccacagactcttcagggccaagatctccacagagatctctgatgtggag
gaagagctctttgtcagtgcagacgaaggggacattgacgtggttgaccaccagacgtac
cgtgaggatgaccagtacatctacatcaagtttgaaatcatgtccgaggccaaatcagca
gccacgcggttcagagagatgtttggtgctctgggaattcccgtggagatcagcatctta
gaacaaggcccaaaaaaaattgaattgcgcattgggaaggcatcacctcccacatttggg
aagtttgcacctccagtagcaagacctccaccacctttgctgacttctgactcagccccc
atgttcatgaccgagctccaaaaccaagaggtccaggatgggtacccagtgagctttgac
tgcatcgtcattggcaaacccctgcccacggttcgctggttcaaggacggcaaagctatt
gaagaaaacgatcactacatgatcaacgaggaccaggaggggtgtcaccagctgatcatc
accgccgtggtccccacggacatgggcgtctaccggtgcctcgctgagaacagcatgggg
gtggcttcaaccaaggctgagctccgtgtggatttgaccagcacggactatgagacagca
gcagatgcaacagagacatcatcttactacagtgccaaggaatatatttcaagccgggaa
caggaggaatccaccactgaggaagagcagctgccccagatctttgatgagcttcatgat
attcatgtggcacctggagcatcactggctaaatttcacctgaaggtgaaagggtaccct
cagcctcgtctctactggttcaaaaatgggcagcccctaaaggcctcggatcgtattctc
aagactgacaggcaggaattccattccctggaaatccgagatgtcaccaaagcagatgct
ggccagtacttgatatttgtcatcaactctgctggctctgcgtattcctcagccaggctg
gtagtcaaagatccctatgagaaagaagagccatcaaaaacagattcccatgagcagctg
acaccaccaagattccttgaaagatttacaaataagaaggtgaaaaagggtgcaagcatc
acattatctgtgaaagttgaaggacatccaccaccaacaatcacttggatgaaagaagag
tctcgagaagacatcctgtggatcaaaccagacactcctggctataaacttgccagttcc
aacatgcaccacagcctgatcctgttggatgtcaagaagaagtacagtggagcttacacg
tgcattgccaccaaccaggctggccagtccatctgcaccgccagcctggaagttgcagat
gtgaaagaggctgaagtcctgacccaggagcgtgtgatggtgtcagaagccatcatgacc
acactgggaactattcagtcctctgaaggagaccttgaagctggcagagaaggtgtgccc
aaaagccctatttcattagctgatgttggctcagaagagttcttccagaaactcacctca
cgtatctcagaaatggtatctgcaaaaataactcaggctaaacttcgagtaccgggtgct
gaaagtgatgatgagtcaagaactccctctgcatctcctcgccatggacgatccagacct
tcatccattgctcaggaatcctcctctgaatctgaagatggggattccagaggggagatc
tttgacgtctacatggtcactgctgactacgtgcccgcggcgcccgacaaggagaccatc
accctgaaggaaggacaatatgtggaagtcctggattcagctcatcccctgaaatggctg
gtcaggactaaacccacaaaatcaagtccctctcgacagggttgggtgtctccagcttac
ctggacaagaaattaaagttgtcaccggagtggggaaccatggaaattccagagtttcct
ggagagtttgtttctgaagatgaatacaaaaggaagctaagtgttctcattcaggagctg
ctgatctcagaggaagattatattcaagatttacagttcctgcagactcatcaccttagg
tacactgagacctgtcccagtgtgccaggagctgttgccagtcagaaatccaccatcttc
aggaatattgatgacattggtcgcttccattccagtgtcttcctccggagcttgcagggc
tgtgacactgatgatgatgtggccatgtgcttcattaagcatgaggcagagtttaacaag
tacatccagtacctggtgggaagggtccaggctgagtcaattgtcgtcagcaaagctgtc
caggatttctacaagagatacacagatgaatttgtaactaatgaagatccctcacagcca
ctgatcccaccactgcagcactacctggaaaaacccataaacaggattcagcagtaccag
acaataattaaggaattaatccgaaacaaagccagaaacagccagaactgcactttgctg
gagcaggcctatgccattgtttctgccctcacccgaagagcagagaacaaccttcacgtc
tcactcattgagaattatccagggaccttggaaagcctcggggaacccatccggcagggc
cacttcattgtgtgggaaggagctccaggagctcgaatggcatggaaaggacacaaaaga
catgttttcctcttcaaaaattatattgtgatctgcaaaccaaagcgagacacaaagaca
gacacctacagctacatcttcaagaacatcatgaagctgaacaacatagacgtgaacgac
ctggtggaaggggatgaccgggcctttgagatctggcacgagcgggaggacttggtgcgc
aaatacctcctgcaggcgcggaccgtgaacatcaagaactcctgggtgaaggagatcttg
ggcatccagcagcggatcagcgagcccatctggatccctccagactttgaggaagaactg
gcagactgcacagctgagctgggagagacagtcaagctggcctgcaaggtgacaggagct
cccaagccatccatcagctggtacaaagatggaaagccagtggaggtggatccccatcac
atcataatagaagatcctgatggttcctgcacactgatcttggacaacctgacaggggct
gacacaggacagtacatgtgcttcgcttccagtcctgctgggaatgccagtaccttggga
aagatccttgttcaagtgccccctcggtttgtgaacaaggtcagaaatgcttatcttgtc
gagggtgaagatgtccagttcacctgcactgtggaaggagcacccaggcctcagatcaga
tggtacaaagatggggtgctgctgaaggacaccggtaaataccagactttcagtgaacca
cggagtggcatcgtagtcctggtggtcaagaacccttccaatgaagatatggggcactat
gaatgtgagctgatgaacagattagggtctgccaaaagtggagcagagctttaccaccac
agcgccgcagccctgacccaggagaggagaggagaccaagccatcaccattgaaggaatg
acttccccccagtcagagacggagacttctgtgcaggcctcgctccagcgcgctgataag
gagatcaagacagccctgaaaaaactcatggactcagcatcactgctggtgactctcccc
ccgggcatgcgagcagatggtggctttggccttggccctcctgggcctgttccttcagag
cactcaggggcagcagccgggccctccgtggtagttcatgaagccagtacccaaacccag
gctgctggagaccatgccaaagcacagaggcaggttccagctgaagaaccaggggtgcca
aagcccagccctgctccttcccgggaagaggaggctgctggaggtgcaagcgctcgggaa
cgcactgttcccattgacagaacatcaccagatgcaggggcaggaggctggtacaggaga
gaaggagacgtggtcgtgcacagtgaagtttatatcgaaaccacagaaagaactcgtgtg
tataagactgaggagaagactccaacaagtcctccctacatgcaagtgacaatagaggat
gtgcaggtgaactctggggaatgtgccaaattccaggcagtcattgaaggaacccctcag
cccacagttttgtggtttaagggcacctcactgctgatggacagcgacagggtccatcag
gggaaggaaggaacaacgtatttcttagtcgtggacaatgctgccttggaagacggtggt
gtttatacctgcgttgccaaaaatgctggaggggaggttttgtgcaaagcagagctcgtc
gtacgtgaagctaagaaagaccaagaaggaaagaaagtggccaccaggagaaagctccac
tcccattatgaggttaagcaggagattggaaggggctgcttcagctttgtgaaacgggtg
gtgcacaaggggaacagggtgtcctgtgctgccaagttcatccctctgcggagcaaaacc
aagtctcgagctcatcaagagagggatattcttgcctctctgtcccacgacagaattacc
aggctcctggatgagtttgagacacgaaaaacactgatcttgattctggagttatgctcc
agtgaagagctcctggaccgcttattcaagaagaatgtggtcactgaagctgaggtcaaa
ctgtacatcaagcaaattttggaaggaatcaaataccttcatgacaacaacatccttcat
ttggacgtcaagccactgaacatcctcatggtttatcctgagagggaagacctgaagatc
tgtgactttggatttgcccagaggatcacacccgtggagccccagtacagcaaatacggc
tctccggagtttgttgccccagaaattgtttcccagtcaccagtgtcaaaagcaactgat
atctgggctgttggagtcatcacatatttaagcctcacgtgcaagtctccatttgctggg
gagaatgacaggaaaactctcctgaatatccagaacggggaaatttcatggaccattcct
gatgtcgttcacttgagtgaagatgcaaaggacttcatgaaagggatcctgcagcagcac
cccaaatccaggccgagtgctttggactgtctttcccacaaatggttcatgcacaacgtt
cctcttgaagcagctcatttcattaataccaaacagctcaaattcattgtggctcggagc
aagtggcagcgctccctgatgtgctacaaatccatcctggtgatgaggtccatcccagaa
atccttgaaaggacccatgacaacagctccctggccatctcccgacacctcattgaggaa
agcacttcatccagcaccagcggctcctcctcggacaatgaaaactccaatttcccaaaa
aagaggcactttggttccacccctgaactgcacctgcccgtatttgatgtcccaggccat
cccgagcctctgaaatgtgcgagtgaaagggaacttgccaaaagctccatccctccagta
aaacccatgaggaggaaatatgcttcgatgaaagcagaggtgggggacaaatcacccaca
gagagcaaggagctcatggcgagtatcttacaggagaaagaggagaggctccttcccagc
cttcggggagagccatcccaaaaaggtggcactgctgagccctcatccctgagggcttcc
acagaaagcacatcgcttctgcatcagaaagaaaaaccagatacatctttatctgaaaag
gacagaacggaggaggcaggggatgggacagaaaagccatctgcctgtgttcccaggcag
agtgtcattaaaagcaccttctacagccaagcaactgagctgcctgcaaggccgccttcc
tcaccaggcagggagttcagaaggcacctggacagagccagaaggactttccggaagggt
gggtattcaaaagtgcccctcagtggcctccgtgaacccctccttgagcagtttgaactg
gaagaagaagaagaagaaggaggaggagatgatcacaaggaaagtctgctgggatccttg
accaaatctgcgtcgtttgacactgccaggaagccaccacaccctgccattgctggggcc
agccgcagccgttccctggatgactacaggctgagaacctccagatccttgagggaacaa
gatattttggaggaggactgtgatgtattgtcccaggaaagctgccctgaaggcagtgat
cactgtgacatttccgcagggcccggcaagggatgctcagcagacacagcagagccaggg
gatgtcaggagagccagcaaggattgctcaggagagaagccctctccctccacacactgt
gaggggaacgggtgcccacctgctcttatacaacagctagagggacttccagtgtcacct
cttaggagtgagaacaggaagcgtttactgaagaagtcaaaagccactgagattgaggag
gacgctgagtgtttggaaggcaaaagccccattccaactgcccagtgctcagatgtaaca
gcaccatcagctccaaaacatgagagcacaaagggtaaatctgcctctggctgtgcctct
gactctgcttttcaggagggcaaagagtccatttcaaccctcacacagtcagagaccacc
ctgaggtcatctcctccaagtaagagaggcgtgtgtctgccccaggagcctgctcccacc
gacagccacccggatctaacaggtggaagcttgcttatcaaaaggacagccccagcccca
ccttggaaagacaaaaggcagaaacattcagatgaaaagacttctgctcatggcactgct
ggatctgaactcatggagcatgaaagctctgctgttccaacagaacaaaaagaaactgat
ttgcttccagtatgtaaagacaaaagtgaggaaattcctgggaaaagtgttccagcagct
actgtcatgctgggcaaacagccaggtaccctcacctctggtgaaggtgttcctcagaag
ctgaagacccctaaagaggtgagatctgctgtcctggaagatgcagaagaagctgttcca
ggaatcactgcaccatcagcccacagtgatgaaagccaaacacacaagaaggctcctgtt
cactcagacacagcatcagctgtcctgaagggagagcaactccgtgttccccaaatccca
ccaccaggatcagtgccacctctggtctctggtggagcacagcaggctctcagcaagaag
aaacttgctgctctgaggaataaaagctcagcttttgccacagaggttgtttccagtttg
gcccatgaaggagctgaaccccaggaggttcttgaaggccatggctcagatcctgctgct
ctggagagcagacacccagccagagctgtgtcctcccaatgcattgtcctccctcaggtc
tgggagagtgaaaatcaagaacatccagaggtgtcagttcacagtgagatgagatctgtt
gtgacaggaagccgagcagctggacaagctgtggctgctcctttccccaaggctggacac
agggtgtttgagcagcacagggctgggatttcagatggcctggagagtggcagttcaggt
gcattaactccttcacaaccagaagttgctccagcttcagcctatgacctggaatatgag
gaatatccagaggtttatggtgagggtggaggcattgccttagaaagtggaagatgtgat
gctggaaaagctgccccaccactgctccgcagggagcacagtcaggagctgtcacaccac
agatcctctttctacagtgatgaggagtctgctgtgctggagggcttagtggatgagatg
gtttccctctccgaagagatgaatgtttgggcagagtcagtttctggagagaagggaagc
aggaagcacgtttctcctcacagagagatgttctacaaaggcagccaaacacacatggac
agctccttcccttctgtccaacaggatggaagaggagaagtcactgagaaggatggcctt
gcagaaccttaccttgctgtgagtgaggagccaggagtcctggaggagcaggtagcacag
acagttcctcaggaatgtgagcagctggaggacttggcatttgagacctccccttccagc
ccagagagcgtttcctccacagagagcttggacactacaaaaagacccatccacgtgccc
gtgatcaaggacactgggaaacacccagaagtttctttggtgaaaatcaaagacctgtca
gatgaaacacccagtcctggcagcggcccccacaagtttgacatctcagaagtggagcct
gcctatttgaatttctcagatttgtatgacattgtctactttccatttgagtttctgagc
tataagaagccttcgcccaaaccagttcctagacggtttatgcttcttggtcaaagggca
aggtcccctcctgcaggacatctccataaggacaaaaaactgtgcatcagggaacaggaa
gacaagaacaggaagaaccaattagaaatatctgaggattcaaaggcagctaacttatta
gccatggggaaaggggcagagagccaaaaagaaatgtatagctcccaaaaggactgcagt
ggaaagcagaaaagctccttccacaccaagcctggactctttaagccgtatgcaaggtct
cattcagtggagcagtcagtggagcagagtctgaagaagaaagtaaaagcttctgttgcc
catatttcaagaatcctaaaaggaaagacatctcctgagccagaggaagagtttggtgag
ctgggaagtgaggcagcagaaaaggagctgttaataggggctgaaggatctctgaagagg
aaatcagcgctcccttcattcaagctaccaagcctcaccccaaaggagaaagccccgtcg
tttgttgaggagctcatggaccaggctgcggccgcaggacagtgcgtgacgctctcgtgc
cggacggcagctcactcctctctgcacatcagctggttcagagatgggatacctgtccag
agcagcagccggatcctcatctcttccacgctcaaacacttccagctgttaacgattctc
tctgttaatgccgaggattttggtatttacacctgtgtggccacaaactctctgggctca
gcatccacctcttgtgtcataagaaaaacagaggttcccccctgccctccaccccctgac
atcgtggaggtctacaaggatggagtgcagatggtttggaaacctgtggaaaccaacacc
cctgtccactacaccgtccagtgcaagactgaagatggggagtggacaactcttgcttct
gacatcactgactgctgctactatgccagaaacctcccccagggcttcacctaccacttc
aggacagcctgcaccagcaaggcagggatgggcccctacagcgacccctctgccaaagtg
aaaatcactgggaaggatcaaatggaacttcgtgctgccacacaggagctcccatcagct
gcccctgaagaagagagtgaaatgatcacaccccctgagcccttcccaacctaccagacc
tacgccttccaaactgagatcaaaaggggccgattcagcatcgtccggcagtgccgggag
aaggtgagcggcaaggctttggccgctaagatcatcccttactggcaggaggacaagcag
gctgtgctgctggagtaccaggtgctgaggaagctccaccacacaaacatagcccagctg
aagggcgcctacgtcagcccccggcacctggtgctgatccaggagatgtgtgtggggcca
gagctgctccactccttggcgttacggacatcgtactcagaagtggaggtccgagactac
ctgtggcagatcctcagtgccaccgagtacctccatgcacacaacatcctgcacctggac
ctcaggtcagagaacatgatcatcaccgagcccaacctgctgaaactcctggattttggg
aatgcacagttctacacaccagagaagtttattaccatggacaaatgctcggactatgtg
gaaaccatggctccagaactgctgacagagcaaggagcccttccccagactgatatttgg
tccgtcggaatcacagccttcatcatgttgagtgccaactaccccgtcagctcggatgta
ccctgtgaattcctgagaacagccaggaaaggaaaactgaagctgatgcggtgctacgcg
ggtctctccgggggagcagtgtccttcctccagagcaccctgtgtgcaaacccttgggga
aggccgtcagcctccgagtgccttcagagcccgtggctccaggagacaggtctggacaac
aggcagcaggcactggtcaccttccccaccaccaaactgaggaatttcctcatggaacgg
gaaaagaagaggggcctgctgtgctccaagtatggcctcatgattgcacagtga
DBGET
integrated database retrieval system
