Panthera leo (lion): 122204704
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Entry
122204704 CDS
T10741
Symbol
WNK2
Name
(RefSeq) serine/threonine-protein kinase WNK2 isoform X1
KO
K08867
WNK lysine deficient protein kinase [EC:
2.7.11.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04928
Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09150 Organismal Systems
09152 Endocrine system
04928 Parathyroid hormone synthesis, secretion and action
122204704 (WNK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122204704 (WNK2)
01009 Protein phosphatases and associated proteins [BR:
plez01009
]
122204704 (WNK2)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122204704 (WNK2)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: Other
Wnk family
122204704 (WNK2)
Protein phosphatases and associated proteins [BR:
plez01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
122204704 (WNK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
CCTL2_WNK
OSR1_C
Motif
Other DBs
NCBI-GeneID:
122204704
NCBI-ProteinID:
XP_042768233
LinkDB
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Position
D4:1192635..1323003
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AA seq
2173 aa
AA seq
DB search
MDGDGGRRDGPRALTEAGRGAGPAGMAEPAAVPRARAARPGPQRFLRRSVVESDQEEPPG
LEAAEAPGAQPPQPLQRRVLLLCKTRRLIAERARGRPAAPAAPAAAAAAAAVAPPGSPAD
PGPEPAGAQEPGPDPAPAPPGEPREDEAAAAAAAAGREDAAAPEARPEPGRARRGEPEEE
EDDEDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKLTKLERQ
RFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFKVMKPKV
LRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRASFAKSV
IGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTCGIKPAS
FEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRKSSIALR
LWVEDPKKLKGKPKDNGAIEFTFDLEKETPDGVAQEMIESGFFHESDVKIVAKSIRDRVA
LIQWRRERIWPALQPPEQRDPGSPDKARGPPAPLQVQVTYHAKAGPPEPEEPEADQHLLP
AALPASATSLASDSTFDSGQGSTVYSDSQSSQQSAVLGSLADAAPPPTQCVCSPPVSASD
GPVLPYSLPSLGPYQQPAVPGLPGSSIPPPARPPLPQQHFPEPAISFAPVSTGPGQPVPA
GQQPPPLAQPAPLPPVLAPPPVGPLQPVPPHLPPYLAPTSQVVAPAQLKPLQMPPAPLQP
LPQVPAQVPPLPVGPPIAPLASMDSLSTALPDLPAATGPAVPSVPAPSQYFSPAVILPSL
PLSAAAAPLPASPALPLQAVKLPHPTGAPLAVPCRTIVPNVAATATAIPLLAVAPQGVAA
LSIHPAAVAQLPAQPVYPAAFPQMVPGDVPPSPLHAAQNVRAAPSQPAPPTLPQPHQPSV
THLPEQAAAAGGAGSQILLGHPPPYAVDVTAQVPTAPVPAAILSPPLPEVLPPPVPELPQ
LPSSLAPVVVAASQNLPVQTTPLLPPTAHPPPPTGLGVASPCPAVQLTVEPVPEEQSSQE
KQPSAPQSCDRACHTGGRNRMQEALVCPGVPAPVSAVQSLLKPCYGPSYGGSDVPSGREM
SDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKMVECQLETH
NHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDMLSEDTDVDR
GSDPGVSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAAEAPEP
SPPLPLSSVQPEASQDTAPCKDQLSLKEKSGFPASPQHLSQTGPRDTPGGAPAPLLPSSP
PVTALPQDAATPAASPKPEPSVGTAVQAGGPGTSQGMASERETPQPLAETQDTQLSAQPL
GAGGGPCAPPLEAPRYPSGLGEPTSAREAMAQGEPLQAPAPAPSAPSGTPQPTLGQPLPP
LPPAVGAISLATPQLPSPPLGPTGAPQPPSALESDGEGPPPRVGFVDSTIKSLDEKLRTL
LYQEHVPTSSASAGTPVEAGDRDLTLEPQPVPGKSETAPGLGAALEQAGSSPLTAESSLS
QVTTSGLPPAPGAPQDAPASAFPALLEPADQSSGVPGETSARPTPGMQTEDSRASHLQTQ
GTLAAGSPQKHPGQQDGSSPAKTVGRFSVVSTQDEWTLGSPHSLRYSAPPDVYLEEAPHS
PDMKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRRRPPVQKHASLPSSSGVASDFVKKAT
AFLHRSPRAGSPGPETPGRVGVKVPTISVTSFHSQSSYISSDNDSEIEDADIRKELQSLR
EKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPAGRRRKSRSKLKAGKLLNP
LVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPEAASDPCGKAVQTQQPCSVRASLSAD
ICSGLATDGGGAHGSGWTVYHPTSERLTYKSSSKPRARFLSGPVSVSIWSALKRLCLGKE
HSSRSSTSSLVPGPEPGPQPTLHVQAQANNSNNKRGTFTDDLHKLVDDWTSKTVGTTQLK
PSLNQLKQTQRLHGMEAPAGWSPATGETRAMNASRAAVGTPCLAPAPSPLSTAAIPGTTP
GLPMPDSESEKPD
NT seq
6522 nt
NT seq
+upstream
nt +downstream
nt
atggacggcgatggcggccgccgggacggcccccgcgcgctgacggaggccgggcgcggc
gcggggcccgcgggcatggcggagccggcggcggtgccgagggcgcgggcggcgcggccc
gggccccagcgcttcctgcggcgcagcgtggtggagtcggaccaggaggagccgccgggc
ctggaggcggccgaggcgccgggcgcgcagcccccgcagccgctgcagcgccgggtgctg
ctgctctgcaagacgcgccgcctcatcgccgagcgcgcccgcggccgccccgccgcccct
gcggcccccgccgccgccgccgccgccgccgccgtcgcgccgcccggcagccccgccgac
cccggccccgagcccgcgggcgcgcaggagcccggcccggaccccgcgcccgcgcccccc
ggagaaccccgcgaggacgaggcggcggcggcggcggcggcggcggggcgggaggacgcg
gcggcgccggaggcgaggcccgagccagggcgcgcccgccggggagagcccgaggaggag
gaggacgacgaggacctcaaggccgtggccacctcgctggacggccgcttcctcaagttc
gacatcgaactgggccgcggctcattcaagacggtctacaaggggctggacacggagacc
tgggtggaggtggcctggtgcgagctgcaggaccggaagctcaccaagctggagaggcag
cggttcaaagaggaggccgagatgctcaagggcctgcagcaccccaacatcgtgcgcttc
tatgacttctgggagtccagtgccagggggaagaggtgcatcgtgctggtgaccgagctg
atgacctcggggacgctgaagacgtacctgaagcggttcaaggtgatgaagcccaaggtc
ctgcgcagctggtgccggcagatcctgaaggggctgctgttcctgcacaccaggacgccc
cccatcatccaccgggacctcaagtgtgacaacatcttcatcactgggcccaccggctct
gtgaagatcggcgacttgggcctggccactctcaagagggcgtcctttgccaagagcgtg
atcggcaccccagagttcatggcgcccgagatgtacgaggagcattacgacgagtctgtg
gacgtctatgccttcggcatgtgcatgctggagatggccacctcagagtacccctactcc
gagtgccagaatgcagcccagatctaccggaaggtcacctgtggcatcaagcctgccagc
tttgagaaagtgcatgatcctgaaatcaaggagatcatcggggaatgcatctgcaaaaac
aaggaggaaaggtacgagatcaaggacctgctgagccacgccttcttcgcagaggacacg
ggagtgagggtggagctggcagaggaggaccacggcaggaagtctagcatcgccctgcgg
ctctgggttgaggaccccaagaaactgaagggcaagcccaaggacaacggggctatagag
ttcacctttgacctggagaaggagacgccggatggtgtggcacaggagatgatcgagtcg
ggattcttccacgagagcgacgtgaagattgtggccaagtccatccgcgaccgagtagca
ttgatccagtggcggcgagagaggatctggccggcgctgcagcccccggagcagcgggac
ccaggcagccccgacaaggccaggggcccgcccgcacccctgcaggtccaggtgacctac
cacgccaaggctgggccgccggagcccgaggaacccgaggcagaccagcacctcctgcct
gccgcgctgccggccagcgccacctccctggcctcggatagcacgttcgacagcggccag
ggctccacggtgtactcggactctcagagcagccagcagagtgcggtgctgggctcgctg
gcggacgcggccccgcccccgactcagtgcgtgtgcagtcccccggtgagcgcgagtgac
gggcctgtcctgccgtacagtctgccctcgctggggccctaccagcagcctgccgtgcct
ggactgccggggagctccatcccgcccccagcccgccctccgctcccgcagcagcatttc
ccggagccagccataagttttgctcccgtgtcgacgggcccgggccagcctgtgcctgct
ggccagcagcctcctccactggcccagccggcgcccttgccccctgtcctggccccaccg
cccgtgggccccctccagccggtgccccctcatctgccgccctacctagctccgacttcc
caggtggtggcccccgctcagctgaagcccctccagatgccgccagcacctctgcagcct
ctgcctcaggtgcctgctcaggtgcctccgcttcccgtcgggccgcccattgcgcccctg
gcctccatggacagcctctccacagctctgcccgacctgccggccgccaccgggcccgcc
gtcccctccgtccccgctccctctcagtatttctctcccgccgtcatcttgccaagcctc
ccgctcagcgccgccgccgccccgctgcccgcgtcaccagccctgcccctgcaggcggtc
aagctgccccaccccaccggggcgcctctcgccgtgccgtgccggaccattgtgccaaac
gtggcggccaccgccaccgccatccctctgctggccgtggccccgcagggtgtggccgcc
ctgtccattcacccggccgctgtggctcagctcccggcccagcccgtgtacccggcagcc
tttccgcagatggtgcccggcgacgtcccgccttctcccctccacgcggcgcagaacgtg
cgggctgccccgtcccagcctgcgccccccacgctgccgcagccccaccagccaagcgtc
acacaccttccagagcaggccgctgcggcaggtggggcggggagccagatcttgcttggc
cacccgcctccatacgctgtggatgtcaccgcccaggtccccacggcacccgtgccagcc
gccatcctctccccacctctgcccgaagtgttgccgcctcctgtccccgagctgcctcag
ctccccagctccctggcccccgtagtggtggcggcctctcagaacttgcctgtccagacc
acgccgctcctgccgcccaccgcccacccaccaccacccaccgggctcggggtcgccagc
ccctgcccggccgtgcagctgacggtggagccggtcccggaggagcagtcctctcaggag
aagcagcccagcgccccgcagagctgtgacagagcttgtcacactgggggacggaaccgg
atgcaggaagcactcgtgtgtcctggtgtgccagccccagtcagtgctgtgcaatccctc
ctcaaaccctgctatggccccagctacggaggctccgacgttccctctggaagagagatg
agcgacagctgtgagggtgcatttggtggtgggaggctggagggcagggccgcccggaaa
catcaccgccggtccacgcgtgcgcgctcccgccaggagagagccagccgcccccggctc
accatcctgaacgtgtgcaacacgggcgacaagatggtggagtgccagctggagacgcac
aatcacaagatggtgacgttcaagtttgacctagacggggacgcgcctgacgagatcgcc
acctatatggtggagcacgacttcatcctgcaggccgagcgagagacgttcatcgagcag
atgaaggacgtcatggacaaggcggaggatatgctcagtgaggacacggatgtcgaccgg
ggctccgaccccggggtcagcccgccgcacctcagcacctgcggcctgggcactggggag
gagagtcgccagtcccaagcaaacgcccccgtgtatcagcagaacgttctgcacacgggc
aagaggtggtttatcatctgcccggtggctgagcacccagcggcggaggcccctgagcct
tcaccgccacttcctctgagctccgtgcagccagaagccagccaagacacagcgccctgt
aaagaccagctgtccttaaaggaaaaatccggcttcccagccagtccacagcatctgagc
caaacaggccccagggacacccctggcggtgcaccggcccctttgctgccatcctcccct
cctgtgactgctctgccccaggatgcggccaccccagccgccagccccaagccagagccc
tcagtggggactgctgtgcaggcagggggcccagggacctctcaggggatggccagtgag
cgtgagaccccccagccactggcagagactcaagacacccagctttctgcacaacccctg
ggtgcaggtggggggccttgtgccccacctctggaggccccccgctacccctcgggtttg
ggagagcccacctcagccagggaggccatggcccagggtgagcccttgcaggctccggcc
cctgcacccagcgcccccagtgggacccctcagcccaccctgggtcagcccctacccccg
ttgccccctgcagtaggggccatcagcctggccactccccagctccccagccccccactg
gggcccactggggccccccagccaccctcggccttggagtcagatggggaggggcctccc
cccagggtgggctttgtggacagcaccatcaagagcctagatgagaagcttcgaactctg
ctctaccaggagcacgtgcccacctcctcagcctctgccgggacccctgtggaggcgggg
gaccgagacttgaccctggagccccagcccgtgccgggaaagtcagaaacagcccctggg
ctgggggctgcattggagcaggctgggtcctcgccattgacagcagaatcatctttgagc
caagtgacaacctcaggtttgcccccggcgccaggtgccccccaggatgcccctgcttct
gccttccctgcactcctggagcccgcagaccagagcagtggggtcccgggggaaacttca
gccaggcccacaccggggatgcagacggaagacagccgggccagccacctgcagacgcag
ggcactctggccgcagggtccccacagaagcatccagggcagcaggacggcagctcacca
gccaaaactgtgggccggttctcggtggtcagcacgcaggacgagtggaccctgggctcc
ccccacagcctgcggtactcggcgccgccagacgtgtacctggaggaggccccccacagc
cccgacatgaagctggccgtgcggagggcgcagacagcctcctccatcgaggtcggcgtg
ggcgagccggtgtccagcgactccggggacgagggtccgcgcaggcggccccctgtgcag
aagcacgcctccctacccagcagcagtggcgtggccagcgacttcgtgaagaaggccacc
gccttcctgcacaggtccccacgggctggctccccgggcccggagacgcccggcagagtg
ggcgtgaaggtgcccaccatcagtgtgacctccttccactcccagtcgtcctacatcagc
agcgacaacgactcggagatcgaggacgccgatatcaggaaggagctgcagagtctgcgg
gagaagcacctgaaggagatctcggagctgcagagccagcagaagcaggagatcgaggcc
ctgtaccgccgcctgggcaagccgctgccccccaacctgggcctcttccacacggcccct
cccgccggccgcaggaggaagagcaggagcaagctgaaggcagggaagctgctcaacccg
ctggtgcagcagctcaaggtcgtggcctccagcacaggtcacttgtcagactgcagcaga
gcccctcctgctaaggaccctgcccaagccggggcagggcccgaagcagcttcagacccg
tgtgggaaggcagttcagacccagcagccttgctcggtgcgggcctccctgtctgcagac
atctgctccggcttagccactgacggaggcggagcgcatggctcaggctggacggtttac
cacccaacgtctgagagactgacctataagtctagtagcaaacctcgcgctcgattcctc
agtggacccgtgtctgtgtccatctggtctgccctgaagcgtctctgtctaggcaaagag
cacagcagtcggtcttccaccagcagcctggtcccgggccctgagccgggcccccagccc
accttgcacgtccaggcacaggcgaacaacagcaacaacaagagaggcaccttcacggat
gacctgcacaagctggtggacgactggacgagcaagacggtggggaccacccagctgaag
ccctcgctcaaccagctgaagcagactcagaggctacacggcatggaggccccggcgggc
tggtccccagccactggcgagacacgggctatgaacgcctctcgagcagcagtggggaca
ccatgtctggccccagcgcccagccctctatccaccgcggccattcctggaaccacccca
ggcctgcccatgccagattctgagagtgagaagcccgactga
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integrated database retrieval system