Panthera leo (lion): 122209604 Help Entry 122209604         CDS       T10741                                  Name (RefSeq) CREB-binding protein isoform X1   KO K04498   E1A/CREB-binding protein [EC:2.3.1.48] Organism plez  Panthera leo (lion) Pathway plez03083   Polycomb repressive complex plez03250   Viral life cycle - HIV-1 plez04024   cAMP signaling pathway plez04066   HIF-1 signaling pathway plez04068   FoxO signaling pathway plez04110   Cell cycle plez04310   Wnt signaling pathway plez04330   Notch signaling pathway plez04350   TGF-beta signaling pathway plez04520   Adherens junction plez04630   JAK-STAT signaling pathway plez04720   Long-term potentiation plez04916   Melanogenesis plez04919   Thyroid hormone signaling pathway plez04922   Glucagon signaling pathway plez04935   Growth hormone synthesis, secretion and action plez05016   Huntington disease plez05152   Tuberculosis plez05161   Hepatitis B plez05164   Influenza A plez05165   Human papillomavirus infection plez05166   Human T-cell leukemia virus 1 infection plez05167   Kaposi sarcoma-associated herpesvirus infection plez05200   Pathways in cancer plez05203   Viral carcinogenesis plez05206   MicroRNAs in cancer plez05211   Renal cell carcinoma plez05215   Prostate cancer Brite KEGG Orthology (KO) [BR:plez00001]  09120 Genetic Information Processing   09126 Chromosome    03083 Polycomb repressive complex     122209604   09125 Information processing in viruses    03250 Viral life cycle - HIV-1     122209604  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     122209604    04330 Notch signaling pathway     122209604    04350 TGF-beta signaling pathway     122209604    04630 JAK-STAT signaling pathway     122209604    04066 HIF-1 signaling pathway     122209604    04068 FoxO signaling pathway     122209604    04024 cAMP signaling pathway     122209604  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     122209604   09144 Cellular community - eukaryotes    04520 Adherens junction     122209604  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     122209604    04935 Growth hormone synthesis, secretion and action     122209604    04919 Thyroid hormone signaling pathway     122209604    04916 Melanogenesis     122209604   09156 Nervous system    04720 Long-term potentiation     122209604  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     122209604    05206 MicroRNAs in cancer     122209604    05203 Viral carcinogenesis     122209604   09162 Cancer: specific types    05211 Renal cell carcinoma     122209604    05215 Prostate cancer     122209604   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     122209604    05161 Hepatitis B     122209604    05164 Influenza A     122209604    05167 Kaposi sarcoma-associated herpesvirus infection     122209604    05165 Human papillomavirus infection     122209604   09171 Infectious disease: bacterial    05152 Tuberculosis     122209604   09164 Neurodegenerative disease    05016 Huntington disease     122209604  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:plez03000]     122209604    03036 Chromosome and associated proteins [BR:plez03036]     122209604    03029 Mitochondrial biogenesis [BR:plez03029]     122209604 Enzymes [BR:plez01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.48  histone acetyltransferase      122209604 Transcription factors [BR:plez03000]  Eukaryotic type   Other transcription factors    Pocket domain CBP     122209604 Chromosome and associated proteins [BR:plez03036]  Eukaryotic type   Histone modification proteins    HATs (histone acetyltransferases)     122209604 Mitochondrial biogenesis [BR:plez03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Coactivators     122209604 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HAT_KAT11 KIX Creb_binding zf-TAZ PHD_P300 RING_CBP-p300 Bromodomain ZZ KIX_2 Med15_N Npa1 Motif Other DBs NCBI-GeneID:  122209604 NCBI-ProteinID:  XP_042777542 LinkDB All DBs Position E3:37976500..38101139 Genome browser AA seq 2445 aa AA seqDB search MAENLLDGPPNPKRAKLSSPGFSANDSTDFGSLFDLENDLPDELIPNGGELGLINSGNLV PDAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSANMASLGAMGK SPLNQGDSSAPSLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNAN FNQTHPALLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGASSSVLA ETLTQVSPQMASHAGLNTAQAGGMTKMGMAGNTSPFGQPFSQTGGQQMGAPGVNPQLSSK QSMVNSLPPFPTDIKNPSVTNVPNMSQMQTSVGIVPTQAITAGPTADPEKRKLIQQQLVL LLHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWK NCTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGTGQQNAASLSNPNPIDPSS MQRAYAALGLPYLNQPQTQLQPQVPGQQPAQPQSHQQMRTLNPLGNNPMNIPAGGITTDQ QPPNLISESALPTSLGATNPLMNDGSGSANLGTLSTIPTAAPPSSTGVRKSWHEHVTQDL RSHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYK IQKELEEKRRSRLHKQGILGNQPALPAPGAQPPGIPQAQPVRPPNGPMPLPVNRVQVSQG MNSFTPMSLGNVQLPQAPMGPRAASPMNHSVPMNSMGSVPGMAISPSRMPQPPNMMGAHS NNIMAQAPSQNQFLPQNQFQSSGGAMSVSSVGLGQPAAQTGVPQGQVPGAALPNPLNMLG PQASQLPCPPVTQSPLHQTPPPASTAAGMPSLQHPSAPGMTPPQPAAPTQPSTPVSSSGQ TPTPTPGSVPSASQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHAQPP GTPLSQAAASIDNRVPTPSSVASAETNSQQPGPEAPMLEMKAEVKTEDTEPDASESKGEP GSAMMEEDLQGSSQVKEETDTTEQKSEPMEVDEKKPEVKVETKEEEESSANGAASQSTSP SQPRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLST IKRKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLG YCCGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQ PQTTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGR TRKENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKS RFVDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSI HFFRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPK RLQEWYKKMLDKAFAERIIHDYKDIFKQATEDRLTSAKELPYFEGDFWPNVLEESIKELE QEEEERKKEESSAASETTEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDL SQKLYATMEKHKEVFFVIHLHAGPVINTLPPIVDPDPLLSCDLMDGRDAFLTLARDKHWE FSSLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKS HAHKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQK MKRVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQH RLQQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMS PAGFPGVARTQPPTTVSAGKPANQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNI NNGVPPGRTGMVTPVGQMAPAGLNVPRPGPVSGPVVPNLPPGQWQQAPLPQQQPMPGMPR PVMSMQAQPAVAGPRMPSVQPPRSISPGALQDLLRTLKSPSSPQQQQQVLNILKSNPQLM AAFIKQRTAKYVASQPGLQPQPGLQPQPGLQAQPGLHQQPGLQNLNAMQAGGPRPGVPPQ QQAMGGLNPQGQALNIMNPGHNPSMASMNPQYREMLRRQLLQQQQQQQQQPPPPPPPPPQ GGAGMAGGMAGHGQFQQPQGPGGYPPAMQQQRMQQHLPIQGSSMGQMAAQMGQLGQMGQP GLGADGTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQMAT SLSSQVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSIDQ GHLGNPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL NT seq 7338 nt NT seq  +upstreamnt  +downstreamnt atggccgagaacttgctggacggaccgcccaaccccaaacgagccaaactcagctcgccc ggcttctcggcgaatgacagcacagattttggatcattgtttgacttggaaaatgatctt cctgatgagctgatccccaatggaggagaattaggccttataaacagtgggaaccttgtt ccagatgctgcttccaaacataaacaactgtcggagcttctgcgcggaggcagcggctct agtatcaacccaggaataggaaatgttagtgccagcagccccgtgcagcaaggcctcggt gggcaggctcaagggcagccgaacagtgcaaacatggccagcctgggtgccatgggcaag agccctctgaaccagggagattcttcagcccccagcctgcccaaacaggcagccagcacc tctgggcccactccccctgcttcccaagcactgaatccgcaagcacaaaagcaagtgggg ctggtgaccagcagccctgccacgtcgcagacgggacctgggatctgcatgaatgctaac tttaaccagacccaccctgccctcctcaatagtaactctggccatagtttaatgaaccag gcccagcaaggacaggcgcaagtcatgaatggctctcttggggcggccggcagaggaagg ggagctgggatgccgtaccccgcgcccgccatgcagggggcctcgagcagcgtgttggcc gagacgttaacgcaggtctcgccgcaaatggccagtcacgcgggactgaacacggcgcag gcaggaggcatgaccaagatgggaatggctggtaacacaagtccatttggacaacccttt agtcaaactggagggcagcaaatgggagcccctggagtgaacccccagttatccagcaaa cagagcatggtcaatagtttgcctcccttccctacagacatcaagaatccttccgtcacc aacgtgccaaacatgtctcagatgcaaacttcggtgggaattgtacccacacaagcgatc acagcaggccccactgcagatcctgaaaagcgcaaactgatacagcagcagctggttcta ctgcttcatgctcacaagtgtcagagacgagaacaagcgaacggagaagttcgggcctgc tctctcccgcattgccgaaccatgaagaatgttttgaatcacatgacacactgtcaggct gggaaagcctgtcaagttgcccattgtgcatcttcacgacaaatcatctctcattggaag aactgcacacgacatgactgtcctgtttgcctccctttgaaaaatgccagtgacaagcga aaccaacaaaccatcctggggtctccagctagtgggattcagaacacgatcggttctgtc ggcacaggccagcagaacgccgcttcgctgagtaacccgaatcccatagaccccagctcc atgcagcgcgcgtatgctgcccttggtctcccctacctgaaccagccccagacgcagctg cagcctcaggttcccggccagcaaccagcacagcctcaaagtcaccagcagatgaggact ctcaaccccctgggaaataacccaatgaacattccagcaggaggaataacaacagatcag cagccgccaaacttgatttcagaatcagctcttccaacttccctcggggccacaaaccca ctgatgaacgacggctcaggctctgcaaacctcgggaccctcagcactatacccacagcg gcacctccttccagcaccggcgtgcggaaaagctggcacgaacatgtcactcaggacctg cggagccacctagtgcataaactggtccaagccatcttcccaacccctgacccggcagcc ctgaaggatcgccgcatggagaacctggtggcctatgctaagaaagtggagggggacatg tatgagtccgccaacagcagggatgaatactatcacttactggcagaaaaaatttacaag atacaaaaagaactagaagaaaagcggaggtcacgtttacacaaacaaggcatcctgggt aaccagcccgccctaccagcccccggggcacagccccctgggattccgcaggcacaacct gtgaggcctccaaatggacccatgcccctgccagtgaatcgcgtgcaggtttctcaaggg atgaattcatttaccccaatgtccttggggaacgtacagttgccgcaggctcccatggga ccgcgtgcagcgtcccccatgaaccactccgtcccgatgaacagcatgggctccgttcca gggatggccatttctccttcccgaatgccccagcctccgaacatgatgggcgctcacagc aacaacatcatggcccaggcgccttcgcagaaccagttcctgcctcagaaccagttccag tcctccggcggggcgatgagcgtgagcagtgtgggcctgggccagccggcggcccagacg ggcgtgccgcagggacaggtgcctggtgctgctcttcctaaccctctgaacatgcttggg cctcaggccagccagctgccttgtccaccagtgacacagtcaccgttgcaccagacgcca ccccctgcttccacggccgcgggcatgccgtctctccagcacccgtcggcacctgggatg actcctccccagccagcagctcccacccagccatcgactcctgtgtcgtcttccgggcag acccctaccccgactcccggctcggtgcccagtgccagccagacccagagcaccccgacg gtccaggcagcagcccaggcccaggtgaccccacagcctcagaccccagtccagcccccg tctgtggccacccctcagtcatcacaacagcagccgacgcctgtgcatgcccagcctccc ggcacaccgctttcccaggcagcagccagcatcgataaccgggtccccactccttcctcg gtggccagcgccgaaaccaactcccagcagccaggacccgaggcaccgatgctggagatg aaagcagaggtcaagactgaggacactgagcctgatgccagtgaatccaagggggagccg gggtctgcgatgatggaggaggatctgcaaggatcttctcaagttaaagaagaaacagac acaacagaacagaaatcggaaccgatggaagtggacgagaagaaaccagaagtcaaagta gaaactaaagaggaagaagagagcagcgctaatggggccgcctctcagtcaacatctcct tcacagccacgcaaaaaaatctttaagccggaagagttacgccaggctctgatgccaacc ctggaagcgctgtaccgccaggacccggagtccttgcctttccggcagcctgtggacccc cagctgctagggatcccggattattttgacattgtgaagaaccctatggacctttccacc atcaagcggaagctggacacggggcagtaccaagaaccctggcagtatgtggatgacgtc tggctcatgttcaacaacgcctggctctataaccggaagacgtcccgggtctataagttc tgcagcaaacttgctgaggtctttgagcaggaaattgaccccgtcatgcagtcccttgga tattgttgtgggcgcaagtatgagttttccccacagactttgtgctgctacgggaagcag ctgtgtacaattcctcgcgacgctgcctactacagctatcagaacaggtatcatttctgt gagaagtgtttcacagagatccagggggagaatgttaccctgggtgacgacccttcacaa ccccagacgacaatttcaaaggatcagtttgaaaagaagaaaaatgataccttagatcct gaaccttttgtcgattgcaaggagtgtggccggaagatgcatcagatttgtgttctgcac tatgacatcatttggccttcgggcttcgtgtgcgacaactgcctgaagaaaaccggcaga actcggaaagaaaacaagttcagtgcgaagagactacagaccacgcgattgggcaaccac ttggaagaccgagtcaacaagtttttgcggcgacagaatcatcccgaagccggggaggtc tttgtccgggtggtggccagctcagacaagactgtggaggtcaagcctgggatgaagtca cggtttgtggattccggggaaatgtctgaatctttcccgtatcgaaccaaagcactcttt gcttttgaggaaattgacggagtggatgtgtgcttctttgggatgcacgtgcaagagtac ggctccgattgcccccctccaaacacaaggcgtgtatacatttcttatctggacagtatt catttcttccggccccggtgcctccggaccgctgtttaccatgagatccttattggatat ttagaatacgtgaagaaattggggtacgtaacaggacacatctgggcctgccccccgagt gaaggagatgactatatcttccattgccacccccctgatcagaaaatccccaaaccaaag cgcctgcaggagtggtacaagaagatgctggacaaggcatttgcagaacggatcattcac gactacaaggacattttcaaacaggcgaccgaagacaggctcaccagtgccaaggagctg ccctattttgagggtgacttctggcccaatgtgctggaggagagcatcaaggagttggag caagaagaagaagagaggaagaaggaggagagcagtgcagccagtgagaccacggagggc agccagggtgacagcaagaatgccaagaagaagaacaacaagaaaaccaataagaataaa agcagcatcagtcgagccaacaaaaagaagcccagcatgcccaacgtgtccaacgacttg tcccagaagctctacgccaccatggagaagcacaaagaggtcttctttgtgattcacctg cacgccgggcccgtcatcaacacgctgccccccatcgtcgaccccgaccccctgctcagc tgtgacctcatggacgggcgtgacgccttcctcaccctcgccagagacaagcactgggag ttctcgtccctgcgccggtccaagtggtccacgctgtgcatgctggtggagctgcacaca cagggccaggaccggtttgtctacacctgcaacgagtgcaagcatcacgtggagacgcgc tggcactgcaccgtgtgcgaggactacgacctgtgcatcaactgctacaacacgaagagc cacgcccacaagatggtgaagtgggggctgggcctggacgacgagggcagcagccagggc gagccgcagtccaagagcccccaggagtcgcggcgcctgagcatccagcgctgcatccag tccctggtgcacgcctgccagtgccgcaacgccaactgctcgctgccgtcctgccagaag atgaagcgggtggtgcagcacaccaagggctgcaagcgcaagaccaacgggggctgcccg gtgtgcaagcagctcatcgccctctgctgctaccacgccaaacactgccaggagaacaaa tgcccggtgcccttctgcctcaacatcaaacacaagctccgccagcagcagatccagcac cgcctgcagcaggctcagctcatgcgccggcggatggccaccatgaacacccgcaacgtg cctcagcagagtctgccttcccctacctcagcaccgcccgggacccccacgcagcagccc agcacgccccagacgccgcagccacccgcccagccccagccctcgcccgtgagcatgtca ccggccggcttccccggcgtggcccggactcagccccccaccacggtgtctgccgggaag cccgccaaccaggtgccggccccgccgccccccgcccagcccccgccggccgcggtggaa gcggcccggcagatcgagcgcgaggcgcagcagcagcagcacctgtaccgggtgaacatc aacaacggcgtgcccccggggcgcacgggcatggtgaccccggtgggccagatggccccc gcgggcctgaacgtgccccggcccggcccggtcagcgggcccgtcgtgcccaacctgccg cccgggcagtggcagcaggcgcctctcccccagcagcagccgatgccgggcatgcccagg cccgtgatgtccatgcaggcccagccggccgtggcagggcctcggatgcccagcgtgcag ccgccccggagcatctcgcccggcgccctgcaggacctgttgcggaccctgaagtcgccc agctccccgcagcagcagcagcaggtgctcaacatcctcaagtcaaaccctcagctgatg gcggccttcatcaagcagcgcacggccaagtacgtggccagtcagcccggcctgcagccc cagcctggcctccagccccagcctggcctccaggcccagcccggcctgcaccagcagccc ggcctgcagaacctgaacgccatgcaagccggcgggccccggcccggcgtgcccccgcag cagcaggcgatgggaggcctgaacccccagggccaggccctgaacatcatgaacccgggg cacaaccccagcatggcgagcatgaacccgcagtacagagagatgctgcgccggcagctg ctgcagcagcagcagcagcagcagcagcagccgccgccgccgccgccgccgccgccacag ggtggcgcgggcatggccgggggcatggccgggcacggccagttccagcagccccaggga cccggaggctacccgccggccatgcagcagcagcggatgcagcagcacctccccatccag ggcagctccatgggccagatggcggctcagatgggacagctcggccagatggggcagccc gggctgggcgcggacggcacccccaacatccagcaggccctgcagcagcggattctgcag cagcagcagatgaagcagcagatcgggtccccgggccagccgaaccccatgagcccccag cagcacatgctctcaggacagccccaggcctcgcacctccccggccagcagatggccacg tccctcagtagccaggtgcggtccccggcccctgtccagtctccgcggccccagtcccag cctccacattccagcccgtcgccacggatccagccccagccttcgccgcaccacgtctcg ccccagaccggttccccccacccaggactcgcggtcaccatggccagctccatagatcag ggacacttggggaaccccgaacagagtgcaatgctcccccagctgaacacccccaacagg agtgcgttgtccagtgagctgtccctggtcggcgacaccacaggagacaccctagaaaag tttgtggagggtttgtag

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