Panthera leo (lion): 122214960
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Entry
122214960 CDS
T10741
Symbol
PAK5
Name
(RefSeq) serine/threonine-protein kinase PAK 5
KO
K05736
p21-activated kinase 5 [EC:
2.7.11.1
]
Organism
plez Panthera leo (lion)
Pathway
plez04012
ErbB signaling pathway
plez04014
Ras signaling pathway
plez04360
Axon guidance
plez04510
Focal adhesion
plez04517
IgSF CAM signaling
plez04660
T cell receptor signaling pathway
plez04810
Regulation of actin cytoskeleton
plez05170
Human immunodeficiency virus 1 infection
plez05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
122214960 (PAK5)
04014 Ras signaling pathway
122214960 (PAK5)
09133 Signaling molecules and interaction
04517 IgSF CAM signaling
122214960 (PAK5)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
122214960 (PAK5)
09142 Cell motility
04810 Regulation of actin cytoskeleton
122214960 (PAK5)
09150 Organismal Systems
09151 Immune system
04660 T cell receptor signaling pathway
122214960 (PAK5)
09158 Development and regeneration
04360 Axon guidance
122214960 (PAK5)
09160 Human Diseases
09162 Cancer: specific types
05211 Renal cell carcinoma
122214960 (PAK5)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
122214960 (PAK5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
plez01001
]
122214960 (PAK5)
Enzymes [BR:
plez01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
122214960 (PAK5)
Protein kinases [BR:
plez01001
]
Serine/threonine kinases: STE group
STE20 family
122214960 (PAK5)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PBD
ABC1
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
122214960
NCBI-ProteinID:
XP_042786099
UniProt:
A0A8C8WIA9
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All DBs
Position
A3:complement(35286234..35387621)
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AA seq
719 aa
AA seq
DB search
MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRRKPMVDPSCIT
PIQLAPMKTIVRGNKPCKETSINGLLEDFDNISVTRSNSLRKESPPTPDQGASSYGQGHR
EENGFITFSQYSSESDTTADYSTEKYREKSLYGDDLDPFYKGSHAAKQNGHVTKTKHGEA
YYSEMKPLKSDIARFPVDYHTHLDSLSKPSEYNELKWEYQRASSSSPLDYPFQFTPSRTA
GTSGCSKESLVFSESEWGPSLDDYDRRPKSSYLNQTSPQPTMRQRSRSGSGLQEPMMPFG
ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVLSPPLSGSDTYPRGPAKLPQS
QSKAGYSSSSHQYPSGYHKATLYHHPSLQTSSQYISTASYLSSLSISSSTYPPPSWGSSS
DQQPSRVSHEQFRAALQLVVSPGDPREYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKM
DLRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRM
NEEQIATVCLSVLRALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKR
KSLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLP
PRVKDLHKVSSVLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH
NT seq
2160 nt
NT seq
+upstream
nt +downstream
nt
atgttcggaaagaaaaagaaaaagattgaaatatctggtccatccaactttgaacacagg
gttcacactgggtttgatccgcaagaacagaaattcacgggcctcccgcagcagtggcac
agcctgttagcagacacggccaacaggcggaagcccatggtagacccttcctgcatcaca
cccatccagctggctcctatgaagacaatcgttagaggaaataaaccgtgcaaagaaacc
tccatcaacggcctgctggaggacttcgacaacatctctgtgactcgttccaactcccta
aggaaagaaagcccgcccaccccagaccagggagcctccagctacggtcaaggccatagg
gaagaaaatggcttcatcaccttctcgcagtattccagcgagtccgataccactgctgac
tacagcactgagaagtatcgagaaaagagtctctatggtgatgacctggatccgttttat
aaaggcagccatgccgccaagcaaaatgggcatgtcacaaagaccaaacacggggaagcc
tactattctgagatgaagcctttgaaatccgatattgccagatttcctgttgattatcac
acacacttggactcactgagcaaaccaagtgaatacaatgagctcaagtgggagtaccag
agagcctcaagcagttcccctctagattatccattccaattcacgccttctagaactgcg
gggaccagcgggtgttccaaggagagtctggtgttcagcgaaagcgagtggggacccagc
ctagatgactatgataggaggccaaagtcatcatacttgaatcagaccagccctcagccc
accatgcggcaaaggtccaggtcaggttcggggctccaggaaccaatgatgcccttcgga
gcaagtgcatttaaaacccacccccaaggacattcgtacaactcctacacctaccctcgc
ctgtccgagcccacaatgtgcattccaaaggtggattacgatcgagcacagatggtcctc
agccctccgctgtcagggtctgacacctaccccagggggcccgccaaactacctcaaagt
caaagcaaagcaggctactcctcaagcagccaccagtacccatctgggtaccacaaagcc
accctctaccaccacccctccctgcagaccagttcacagtacatctccacagcttcttat
ctgagctctctgagtatctcatccagtacctaccccccacccagctggggctcctcttca
gaccagcagccctccagggtgtcccatgaacagtttcgggctgctctgcagctggtggtc
agccccggagaccccagagaatacttggacaactttatcaaaatcggagaagggtcaact
ggcattgtgtgcatcgcaactgagaaacacacagggaaacaagttgcagtgaagaaaatg
gacctccgcaagcaacagagacgagaactgctctttaatgaggttgtgataatgcgggat
taccaccatgacaacgtggttgacatgtataacagctaccttgttggcgatgagctctgg
gtggtcatggaatttctagaaggcggtgccttgacagacattgtcactcataccagaatg
aatgaagaacagatagccaccgtctgtctgtcagttctgagagctctttcctaccttcac
aatcaaggagtgattcacagggacataaagagtgactccatcctcctgacaagtgatggc
cggataaagctatctgactttggtttctgtgctcaagtttctaaagaggtgccgaagagg
aaatcactggttggcactccttactggatggcacctgaggtgatttctaggctaccttat
gggacagaggtggatatctggtcccttgggatcatggtgatagaaatgattgatggcgag
cccccctatttcaatgagccccccctccaggcaatgcggaggattcgggacagtttacct
ccaagagtgaaggacctacacaaggtttcttcagtgctccggggattcctagacctgatg
ctggtgagggaaccctcacaaagagccacagcccaggaactccttggacatccattcttg
aaactggcaggtccgccatcttgcatcgttcccctcatgagacaatacagacatcactga
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