Panthera leo (lion): 122216505
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Entry
122216505 CDS
T10741
Symbol
CAD
Name
(RefSeq) CAD protein
KO
K11540
carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:
6.3.5.5
2.1.3.2
3.5.2.3
]
Organism
plez Panthera leo (lion)
Pathway
plez00220
Arginine biosynthesis
plez00240
Pyrimidine metabolism
plez00250
Alanine, aspartate and glutamate metabolism
plez01100
Metabolic pathways
plez01240
Biosynthesis of cofactors
Module
plez_M00051
De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
122216505 (CAD)
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
122216505 (CAD)
00220 Arginine biosynthesis
122216505 (CAD)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
plez01002
]
122216505 (CAD)
Enzymes [BR:
plez01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.3 Carboxy- and carbamoyltransferases
2.1.3.2 aspartate carbamoyltransferase
122216505 (CAD)
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.2 In cyclic amides
3.5.2.3 dihydroorotase
122216505 (CAD)
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.5 carbamoyl-phosphate synthase (glutamine-hydrolysing)
122216505 (CAD)
Peptidases and inhibitors [BR:
plez01002
]
Cysteine peptidases
Family C26: gamma-glutamyl hydrolase family
122216505 (CAD)
Metallo peptidases
Family M38: beta-aspartyl dipeptidase family
122216505 (CAD)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
CPSase_L_D2
CPSase_L_D1
GATase
CPSase_sm_chain
OTCace_N
OTCace
CPSase_L_D3
ATP-grasp
Dala_Dala_lig_C
MGS
ATPgrasp_Ter
Amidohydro_1
DHOase
ATP-grasp_3
GARS_A
Peptidase_C26
Motif
Other DBs
NCBI-GeneID:
122216505
NCBI-ProteinID:
XP_042789359
UniProt:
A0A8C8WJT9
LinkDB
All DBs
Position
A3:complement(118157796..118181142)
Genome browser
AA seq
2225 aa
AA seq
DB search
MAALMLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPADETDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSATHTLHQWLEQHGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTEPSALPFLDPNARPLVPEVSIKAPRVFNAGGTPRILA
LDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGVFLSNGPGDPASYPSVVSTLSRVL
SEPDPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
TDSLPAGWLPLFTNANDRSNEGIVHDSLPFFSVQFHPEHQAGPSDMELLFDIFLETVKEA
TAGNPGGQTVRERLVERLCPPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGILLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWVGYSVERLYELTRIDRWFLHRM
KRIIAHAQLLEQHRGQPLPPDLLHQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIR
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ARDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LEQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDIHVHLREPGGTHKEDFASGTAAALAGGVTMV
CAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDNVAQWMEHFETWPSHLPIVAHAERQSVAAILMVAQLTQRSVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSRDDLERLGPGKGEVRPELGSRQDVEALWENMTVI
DCFASDHAPHTLEEKCGPRPPPGFPGLETMLPLLLTAVSEGRLTLDDLLQRLHHGPRRIF
HLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGVVPQLAPPAPATSEITTTPERPRRAIPGLPDGRFHLPPRIHRASD
PGLPAEEPKEKSSRKAAEPELMGTLDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS
LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPPNVRAFVAARGTKQEEFESIEEALPDTDVLYMTRIQKERFDSSQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq
6678 nt
NT seq
+upstream
nt +downstream
nt
atggcggccctgatgttggaggatgggtcggtcctgcggggccagccctttggggccgct
gtgtcgactgccggtgaagtggtgtttcaaaccggcatggtcggctaccccgaggccctt
actgacccttcctacaaagcacaaatcttagtgctgacatatcctctgatcggcaactat
ggcatccctgcagatgaaacggatgagttcggtctcagtaagtggtttgaatcctcaggg
atccatgtggcaggactggtggtgggagagtgctgccccacacccagccactggagcgcc
acccacaccctgcatcagtggctggaacagcatggcatacctggcctgcaaggagtggat
actcgggagctgactaagaagttgagagagcaagggtctctgctgggaaagctggtccaa
gatggaacagagccttcagccctgccattcttggaccccaatgcccgccccctggtgcca
gaggtctcgattaaggctccacgggtcttcaatgcagggggcacccctcggatccttgct
ttggattgtggtctcaagtacaatcagatccgatgtctgtgccagcgtggagctgaggtc
actgtggtaccgtgggaccatgcattagacagccaggagtatgagggtgtcttcctgagt
aatggccctggtgaccccgcctcctatcccagtgtggtatccacactgagccgtgtctta
tctgagcctgatccccgacctgtcttcgggatctgtctgggacaccagctgttggcctta
gccattggggccaagacatacaagatgagatatgggaaccgaggccataatcagccatgc
ttgctagtgggctctgggcgctgctttctgacatcccagaaccatgggtttgctgtggaa
acagactcactgccagccggctggcttcctctctttaccaacgccaatgatcgttccaat
gaaggcattgtacatgacagcctgcccttcttcagtgtccagtttcacccagagcaccaa
gctggtccttcagatatggagctgctttttgatatctttctggaaactgtgaaagaagcc
acagctgggaaccccgggggccagacagttcgagagcggctggttgagcgcctctgtccc
cctgggattcccaccccaggctctgggcttccaccaccacgaaaggttctgatcctgggc
tctgggggcctctccattggccaagctggggagtttgactactcaggctctcaggcgatt
aaggccctgaaggaggaaaacatccagacgttgctgataaaccccaacattgccacagtg
cagacttcccaggggctggctgacaaagtctatttccttcccataacacctcactatgta
acccaggtgatccgtaatgagcgcccagatggcatcttactgacttttgggggccagaca
gctctgaattgtggtgtggagctaaccaaggctggagtgttagctcggtatggggtccgg
gtcctgggcacacctgtggaaaccattgaactgactgaagatcggcgggcatttgcctcc
aggatggcagagattggagagcatgtggcccccagtgaggcggcaaattctcttgaacag
gcccaggcagctgctgagcggctgggatatcctgtgctggttcgtgcggcctttgccctg
ggtggcctgggctctggctttgcctccaacagggaggagctctctgctcttgtggcccca
gcttttgcccatactagccaagtgctggtagataagtccctgaagggatggaaggagatt
gagtacgaagtggtgagagatgcctatggcaactgtgtcacggtgtgtaacatggagaat
ttggacccattgggcatccacactggagaatccatagtcgtggctccaagccagacactg
aatgacagggaataccagctactgcggcagacagccatcaaggtgacccagcaccttgga
atcgtcggggaatgcaatgtgcagtacgccttgaaccccgagtctgagcagtattacatc
attgaagtgaatgccaggctctctcgaagctctgccctggccagtaaggccacaggttat
ccactggcctatgtggcagcgaagctagcgttgggcatccctctacctgagctcaggaac
tcagtgacagggggaacagcggcttttgaacctagcctggattattgtgtggtaaagatc
cctcgctgggacctcagcaagttcctccgtgtcagcacaaagatcgggagctgcatgaag
agcgtcggtgaagtcatgggcattgggcgttcttttgaggaagccttccagaaggctctt
cgcatggtagatgagaactgtgtgggctttgatcacacagtaaagccggtcagtgacatg
gagttggagacgccaactgataagcggatctttgtggtagcagctgctctgtgggttggc
tattctgtggagcggctgtatgaactcacacgcatcgaccgctggttcctgcaccggatg
aagcggattatagcacacgcccagctgctggaacagcaccgtggacagcctttgccccca
gacctgctacaccaggccaagcgccttggcttctcagacaagcagatcgcccttgcggtt
ctgagcacagagctggcggttcgcaaactgcgtcaggagttgggaatctgcccagcagtg
aaacagattgacacagttgcagctgagtggccagcccagacaaattatttgtacctgaca
tactggggcaccacccatgatctcacctttcgaacgcctcacgtcctggtccttggctct
ggcgtctaccgtataggctccagcgttgagtttgactggtgtgctgtgggctgcatccgg
cagctccgaaagatgggatataagaccatcatggtgaactacaacccagagacagtcagc
actgactatgacatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatg
gacatctatgagctagagaatcctgaaggtgtgatcctatctatgggtggacagctgccc
aacaacatggccatggctctgcatcggcagcagtgccgggtgctgggtacttcccctgaa
gccatcgactcggctgagaaccgtttcaagttctcccggctcctcgacaccattggtatc
agccaacctcagtggagggaactcagtgacctagagtctgctcgccagttctgccagaca
gtggggtacccctgcgtggtgcgcccctcctacgtgctgagtggcgctgctatgaatgtg
gcctacactgacggcgacctggagcgcttcctgagcagtgcagcagccgtctctaaggag
caccctgtggtcatctccaagttcatccaggaggctaaggagattgatgtggatgctgtg
gcccgtgatggtgtagtggcagccattgccatctctgagcatgtggagaatgcaggcgtg
cattcaggcgatgccacactggtgaccccaccgcaggacatcactgccaaaaccctggag
cggattaaagccattgtgcacgctgtgggtcaggagctgcaggtcacaggacccttcaat
ctgcagctcattgccaaggatgaccagctgaaagttatcgaatgcaacgtgcgtgtctct
cgctccttccctttcgtctcgaagacactaggtgtggacctagtagccttggccacacgc
gtcatcatgggggaagaagtggaacctgtggggctcatgactggctccggagtcgtgggg
gtaaaggtgcctcagttctcgttctcacgcttggcgggtgctgatgtggtgttgggtgtg
gagatgaccagtaccggggaagtggctggctttggggagagccgttgcgaggcctacctc
aaggccatgctaagcactggctttaagatccccaagaagaacatcttgctgaccattggc
agctataagaacaaaagtgagctgctcccaactgtgcggctgctggagagcctgggctac
agcctctacgccagcctgggcactgctgacttctacactgagcatggtgtcaaggtaaca
gctgtggactggcactttgaggaggcagtggatggtgagtgcccaccgcagcgaagcatc
ttggagcagctggctgagaatcactttgagctagtgattaacctgtcaatgcgtggagct
gggggccggcgtctctcttcctttgtcaccaagggctaccgtacccggcgcctggccgct
gacttctctgtgcctctcatcatcgatatcaagtgcaccaaactgtttgtagaggcccta
ggccagattgggccagcccctcctttgaaggtgcacgttgactgtatgacttcccaaaag
cttgtgcgactacctggactgattgacatccatgtgcacctgcgggaaccaggggggaca
cacaaggaggactttgcctcaggcacagctgctgccttggctgggggcgtgaccatggtg
tgtgccatgcctaatacccggccccctatcattgatgcccctgccctggccctggcccag
aagctggcagaggctggcgcacgctgtgactttgccttatttcttggggcctcgtcagaa
aatgcagggaccctgggtgctgtggctgggtctgctgctgggctaaagctctacctcaac
gaaaccttctctgagcttcggctggacaacgtggcccagtggatggagcactttgagaca
tggccatcccacctccccattgtcgcccatgcggagcgacagagtgtcgccgccatcctc
atggtggcccagctgacccagcgctcagtgcacatatgtcatgtggcacggaaggaggag
atcctgctgattaaagccgcaaaggcccgagggctgccagtgacctgtgaggtggcgccc
caccatctgtttctaagccgcgatgacctggagcgcctggggcccgggaagggcgaggtc
cggcctgagcttggctcccgccaggatgtggaggccctgtgggagaacatgactgtcatc
gactgcttcgcctcagatcatgccccccacaccttggaggagaagtgtgggcccaggcct
ccaccaggcttcccggggctggagaccatgctgccgctgctgctcacggctgtcagcgag
ggccggctcactctggatgacctactgcagcggctgcaccacggtcctcggcggatcttc
cacctgcccccacaggaggacacctatgtggaggtggatctggagcatgaatggaccatc
cccagccacatgcccttctccaaggcccactggacacccttcgaagggcagaaggtcaag
ggcaccgtccgccgtgtggtcctacgaggcgaggtggcctatattgacgggcaggtcctg
gtgcccccgggctacggacaggatgtacgcaagtggcctcagggggttgttccccagctc
gcacctccagcccctgccaccagtgagataaccacgacacccgaaaggcctcgccgggct
atcccagggcttcccgatggccgcttccacctgcctccccgaatccaccgagcctctgac
ccaggtctgccagctgaagagccaaaggaaaagtcctctcggaaggcagctgaaccagag
ctcatgggaacccttgatggcacctgctaccctccaccaccagtacctagacaggcgtca
ccccagaacctggggacccctggcctgctgcacccccagacctcacccctgctgcactca
ttagtgggtcaacatatcctgtctgtccagcagttcaccaaggatcagatgtctcacctg
ttcaatgtggcacacacactgcgtatgatggtccagaaggagcggagcctcgacatcctc
aaggggaaggtgatggcctccatgttctacgaggtgagcacgcggaccagcagttccttt
gcggcagccatggcccggctggggggcgctgtgctcagcttctcagaagccacgtcttca
gtccaaaagggtgaatccctggctgactctgtgcagaccatgagctgctacgccgacgtt
gttgtgcttcggcatccccagcctggagccgtggagctggcagccaagcactgtcgaagg
ccagtgatcaatgctggcgatggggttggagagcatcccacgcaggccctgctggacatc
ttcaccatccgggaggagcttgggactgtcaatggcatgacgatcacaatggtgggggac
ctgaagcatggacgcacggtgcattccctggcctgcctgctcacccagtaccgtgtcagc
ctgcgctacgtggcacctcccagcctgcgcatgccacccaatgtgcgggcctttgtggca
gcccgcggcaccaagcaggaggaatttgagagcattgaggaagcgctgcctgacactgat
gtgctctacatgactcgaatccagaaggaacgctttgactctagtcaggagtatgaagct
tgctttggccagttcattctcactccccacatcatgacgcgggccaagaagaagatggtg
gtgatgcacccgatgcctcgagtcaatgagataagtgtggaggtggactcagacccccga
gcagcctacttccgccaggccgagaacggcatgtacatacgcatggctctgttagccact
gtgctgggccgcttctag
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integrated database retrieval system
