Panthera leo (lion): 122217592
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Entry
122217592 CDS
T10741
Symbol
IDO2
Name
(RefSeq) indoleamine 2,3-dioxygenase 2 isoform X1
KO
K00463
indoleamine 2,3-dioxygenase [EC:
1.13.11.52
]
Organism
plez Panthera leo (lion)
Pathway
plez00380
Tryptophan metabolism
plez01100
Metabolic pathways
plez01240
Biosynthesis of cofactors
plez05143
African trypanosomiasis
Module
plez_M00038
Tryptophan metabolism, tryptophan => kynurenine => 2-aminomuconate
plez_M00912
NAD biosynthesis, tryptophan => quinolinate => NAD
Brite
KEGG Orthology (KO) [BR:
plez00001
]
09100 Metabolism
09105 Amino acid metabolism
00380 Tryptophan metabolism
122217592 (IDO2)
09160 Human Diseases
09174 Infectious disease: parasitic
05143 African trypanosomiasis
122217592 (IDO2)
Enzymes [BR:
plez01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.52 indoleamine 2,3-dioxygenase
122217592 (IDO2)
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Motif
Pfam:
IDO
PrnB
Motif
Other DBs
NCBI-GeneID:
122217592
NCBI-ProteinID:
XP_042790697
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Position
B1:complement(42506159..42575043)
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AA seq
407 aa
AA seq
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MEPQSQNLKTIPLLSLGRFHISEEYGFLLPNPLKELPDHYRPWMEIANKLPHLIESHQLQ
AQVDKMPLLTCQFLQNYREQRLAHLVLSFITMGYVWQKGETQPKEVLPRNLALPFVEVSR
NLGIPPILVHADLVLTNWTIRDPERPLEIRNLDVIFSFPGEESLRGFILVTVLVEKAAVP
GIKALVQAVNAILQPSQNLLLQALQRLRLCIQDITRTLGQMHDYVDPDIFYAVIRIFLSG
WKDNPAMPVGLIYEGVSPEPLKYSGGSAAQSTVLHAFDEFLGICHSKESADFLLRMREYM
PPSHKAFIEEIHSTPSLRDHIRSSGNGQLLTAYNQCVEALAELRSYHITVVTKYLITAAT
KAKGRRPNYVPGPPLALEERGTGGTVVLSFLKSVRDKTLEAILHQSD
NT seq
1224 nt
NT seq
+upstream
nt +downstream
nt
atggaacctcaaagtcagaatttgaagacaataccattattatctttaggaagatttcat
atttctgaagagtatggctttcttctgccaaatcctttgaaagaacttccagatcattat
agaccttggatggaaattgctaacaaactccctcacttgattgagagtcaccagcttcaa
gctcaagtggacaagatgcccctcctgacctgccagttcctccagaattaccgggaacag
cgcctggcccacttggttctgagctttattaccatgggctatgtctggcagaaaggagag
acgcagcccaaagaggttctgccaagaaatcttgcccttccctttgttgaagtctccagg
aacttgggcatccctcctatcctggtccatgcagacttggtgctgacaaactggaccatt
agggatcctgaaagacccctggaaatcaggaacttggacgtcattttctcatttcctggg
gaagaaagcctgcgtggctttatactggtgactgttttggtggagaaagcagcagtacct
gggattaaggcacttgttcaggcagtgaatgccatcttgcagcccagccagaacttgttg
cttcaagccctgcagcgactgagactctgcattcaggatatcaccagaactttaggacaa
atgcatgattatgttgatccagacatattttatgcagtcatccggatctttctctctgga
tggaaggataacccagcaatgccggtggggttgatctatgaaggagtctccccagagccc
ctgaaatactctggggggagtgcagctcagagcacagtgcttcatgcctttgatgagttc
ttaggcatttgtcacagcaaggaaagtgctgattttctgctcaggatgagggagtacatg
cctccttcccataaggcctttatagaagaaattcactcaactccttcactgagagaccac
attcggtcctctggaaatggccaacttctgacagcctataaccagtgtgtggaggccctg
gcggagctacgcagctatcacatcactgtggtgaccaaatacctcatcacagcagccacc
aaagcaaagggcaggaggccgaactatgtccctgggccaccactagccctagaagagagg
ggcacaggtgggactgtagttctgagcttcctgaagagtgtcagggataagaccttagag
gcaattctccaccaaagtgattaa
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