KEGG   Panthera leo (lion): 122226651
Entry
122226651         CDS       T10741                                 
Name
(RefSeq) sterol 26-hydroxylase, mitochondrial isoform X1
  KO
K00488  cholestanetriol 26-monooxygenase [EC:1.14.15.15]
Organism
plez  Panthera leo (lion)
Pathway
plez00120  Primary bile acid biosynthesis
plez01100  Metabolic pathways
plez03320  PPAR signaling pathway
plez04979  Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:plez00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    122226651
 09150 Organismal Systems
  09152 Endocrine system
   03320 PPAR signaling pathway
    122226651
  09154 Digestive system
   04979 Cholesterol metabolism
    122226651
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:plez00199]
    122226651
Enzymes [BR:plez01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.15  cholestanetriol 26-monooxygenase
     122226651
Cytochrome P450 [BR:plez00199]
 Cytochrome P450, animal type
  CYP27 family
   122226651
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 122226651
NCBI-ProteinID: XP_042806118
LinkDB
Position
C1:201689494..201720190
AA seq 535 aa
MDRVAALRGARLRWALLGTRVALPGLCPHGARAKSAIPAAVSATAETPGNGPGDRRLRTL
EEIPGPGQLRSFFQLLVQGYVLHLHKLQMLNKTKYGPMWVTRLGPQMHVNLASAPLLEQV
MRQESKYPVRNDMELWKEHRDQQGLAYGPFTTEGHHWYQLRQALNQRMLKPSEAALYTDA
LNEVIDDFLAHLNHLLAESASGDHVSDMAHHFYYFALEAICYILFEKRIGCLERPIPQDT
VAFVRSVGLMFQNSLYVTFLPKWSRSLLPFWKRYLDGWNTIFSFGKKLIDQKLKEIETQL
QKSGPDEVQISGYLHFLLTRGQLSAHEVMGSLPELLLAGVDTTSNTMTWALYHLSKNPEI
QAALHKEVVGVVPPGHVPKYKDLAHTPLLKAVLKETLRLYPVVPTNSRVITEKEIEVGGF
LFPKNTQFVFCHYVVSRDPDIFPEPESFWPYRWLKKSQPATPGVQHPFGSVPFGYGVRAC
LGRRIAELEMQLLLSRLIQKYEVVLAPETGEVRSVARIVLVPNKKVGLRFLQRQC
NT seq 1608 nt   +upstreamnt  +downstreamnt
atggatcgcgtggctgcgttgaggggcgcgaggctgcggtgggcgctgctggggacgcgg
gtggccctccctggcctttgcccgcacggggccagagccaagtccgcgatccccgccgcc
gtctcggccaccgccgagactcctggaaacgggcctggcgaccggaggctgcggaccctg
gaggagattccggggccggggcagctgcgcagtttcttccagctgttagtgcaaggctac
gttctgcacttacacaagctccagatgctgaacaagaccaagtatggtccaatgtgggta
acccgcctagggcctcagatgcatgtgaacctggccagtgccccactcctggagcaagtg
atgcggcaagagagcaagtacccagtacggaacgacatggaactatggaaggagcaccgg
gaccaacagggcctggcttatgggcccttcaccacggaaggacaccactggtaccagcta
cgccaagctctgaaccagcggatgctgaagcccagtgaggctgcgctctacaccgatgct
ctgaatgaggtgattgacgacttcctggcccacctgaaccatcttttggcagagagtgcc
tcaggggaccacgtgtctgacatggctcaccatttctactactttgccttggaagctatt
tgctacatcctgtttgagaaacgtattggctgcctggagcgacccatcccccaggacacc
gtggccttcgtcagatctgtcgggctcatgttccagaactcactctatgtcaccttcctc
cccaagtggagccgttccttgctgcctttctggaagcgatatctggatggctggaacacc
atcttctcttttgggaagaagctgattgatcagaaactcaaggagatagagacccagctg
cagaaaagtgggccagatgaagtgcagatatctggctacctgcacttcctgctcaccaga
ggacagctcagtgctcatgaggtcatgggcagcctgcccgagctgctcctggctggcgta
gacacgacatccaacacaatgacgtgggccctgtaccatctttcaaagaacccagagatc
caggctgccttgcataaggaagtggtgggcgtggtaccccccgggcacgtgcccaagtac
aaggacttagcacacacgcccctgctcaaagctgtgcttaaggagaccctgcgcctttac
cccgtggtccccacgaactcccgggtcatcacggaaaaggaaatcgaagtcggtggcttc
ctcttccccaagaacacccagtttgtgttctgtcactatgtggtgtcccgtgaccctgac
atcttccctgagccagagagcttctggccctaccgctggctgaagaagagccagcctgct
acccctggggtccagcatccatttggctctgtgccctttggctatggggtccgggcttgc
ctgggtcgcaggattgcggaactggagatgcagctgctgctgtcaaggctgatccagaag
tatgaggtggtcctggcccccgagacgggggaggtgaggagcgtggcccgcatcgtcctg
gttcccaataagaaggtgggcctgcgtttcctgcagagacagtgctga

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