KEGG   Pongo abelii (Sumatran orangutan): 100435254
Entry
100435254         CDS       T01416                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta
  KO
K05425  interleukin 12B
Organism
pon  Pongo abelii (Sumatran orangutan)
Pathway
pon04060  Cytokine-cytokine receptor interaction
pon04620  Toll-like receptor signaling pathway
pon04622  RIG-I-like receptor signaling pathway
pon04625  C-type lectin receptor signaling pathway
pon04630  JAK-STAT signaling pathway
pon04658  Th1 and Th2 cell differentiation
pon04936  Alcoholic liver disease
pon04940  Type I diabetes mellitus
pon05133  Pertussis
pon05134  Legionellosis
pon05140  Leishmaniasis
pon05142  Chagas disease
pon05143  African trypanosomiasis
pon05145  Toxoplasmosis
pon05146  Amoebiasis
pon05152  Tuberculosis
pon05162  Measles
pon05164  Influenza A
pon05168  Herpes simplex virus 1 infection
pon05171  Coronavirus disease - COVID-19
pon05200  Pathways in cancer
pon05205  Proteoglycans in cancer
pon05321  Inflammatory bowel disease
pon05330  Allograft rejection
pon05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:pon00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    100435254 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    100435254 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    100435254 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    100435254 (IL12B)
   04625 C-type lectin receptor signaling pathway
    100435254 (IL12B)
   04658 Th1 and Th2 cell differentiation
    100435254 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    100435254 (IL12B)
   05205 Proteoglycans in cancer
    100435254 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    100435254 (IL12B)
   05164 Influenza A
    100435254 (IL12B)
   05162 Measles
    100435254 (IL12B)
   05168 Herpes simplex virus 1 infection
    100435254 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    100435254 (IL12B)
   05134 Legionellosis
    100435254 (IL12B)
   05152 Tuberculosis
    100435254 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    100435254 (IL12B)
   05145 Toxoplasmosis
    100435254 (IL12B)
   05140 Leishmaniasis
    100435254 (IL12B)
   05142 Chagas disease
    100435254 (IL12B)
   05143 African trypanosomiasis
    100435254 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    100435254 (IL12B)
   05330 Allograft rejection
    100435254 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    100435254 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    100435254 (IL12B)
   04936 Alcoholic liver disease
    100435254 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:pon04052]
    100435254 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:pon00536]
    100435254 (IL12B)
Cytokines and neuropeptides [BR:pon04052]
 Cytokines
  Interleukins
   100435254 (IL12B)
Glycosaminoglycan binding proteins [BR:pon00536]
 Heparan sulfate / Heparin
  Cytokines
   100435254 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_3 Ig_5 Ig_2 Ig_4 fn3 ig
Other DBs
NCBI-GeneID: 100435254
NCBI-ProteinID: XP_002816186
Ensembl: ENSPPYG00000016000
UniProt: H2PH86
LinkDB
Position
5:complement(156901410..156917659)
AA seq 328 aa
MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITW
TLDRSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEALSHSFLLLHKKEDGIWSTDILKDQ
KEPKNKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERV
RGDNKEYEYSVECQEDSACPAAEERLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKN
LQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVIC
RKNANFSVRAQDRYYSSSWSEWASVPCS
NT seq 987 nt   +upstreamnt  +downstreamnt
atgtgtcaccagcagttggtcatctcttggttttccctggtttttctggcatctcccctc
gtggccatatgggaactgaagaaagatgtttatgtcgtagaattggattggtatccggat
gcccctggagaaatggtggtcctcacctgtgacacccctgaagaagatggtatcacctgg
accttggaccggagcagtgaggtcttaggctctggcaaaaccctgaccatccaagtcaaa
gagtttggagatgctggccagtacacctgtcacaaaggaggcgaggctctaagccattcg
ttcctgctgcttcacaaaaaggaagatggaatttggtccactgatattttaaaggaccag
aaagaacccaaaaataagacctttctaagatgcgaggccaagaattattctggacgtttc
acctgctggtggctgacaacaatcagtactgatttgacattcagtgtcaaaagcagcaga
ggctcttctgacccccaaggggtgacgtgcggagctgctacactctctgcagagagggtc
agaggggacaacaaggagtatgagtactcagtagagtgccaggaggacagtgcctgccca
gctgctgaggagaggctgcccattgaggtcatggtggatgctgttcacaagctcaagtat
gaaaactacaccagcagcttcttcatcagggacatcatcaaacctgacccacccaagaat
ttgcagctgaagccattaaagaattctcggcaggtggaggtcagctgggagtaccctgac
acctggagtactccacattcctacttctccctgacattctgcgttcaggtccagggcaag
agcaagagagaaaagaaagatagagtcttcacagacaagacttcagccacggtcatctgc
cgcaaaaatgccaactttagcgtgcgggcccaggaccgctactatagctcatcttggagc
gaatgggcatctgtgccctgcagttag

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