KEGG   Panthera pardus (leopard): 109257574
Entry
109257574         CDS       T06062                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta isoform X1
  KO
K05425  interleukin 12B
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04060  Cytokine-cytokine receptor interaction
ppad04620  Toll-like receptor signaling pathway
ppad04622  RIG-I-like receptor signaling pathway
ppad04625  C-type lectin receptor signaling pathway
ppad04630  JAK-STAT signaling pathway
ppad04658  Th1 and Th2 cell differentiation
ppad04936  Alcoholic liver disease
ppad04940  Type I diabetes mellitus
ppad05133  Pertussis
ppad05134  Legionellosis
ppad05140  Leishmaniasis
ppad05142  Chagas disease
ppad05143  African trypanosomiasis
ppad05145  Toxoplasmosis
ppad05146  Amoebiasis
ppad05152  Tuberculosis
ppad05162  Measles
ppad05164  Influenza A
ppad05168  Herpes simplex virus 1 infection
ppad05171  Coronavirus disease - COVID-19
ppad05200  Pathways in cancer
ppad05205  Proteoglycans in cancer
ppad05321  Inflammatory bowel disease
ppad05330  Allograft rejection
ppad05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    109257574 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    109257574 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    109257574 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    109257574 (IL12B)
   04625 C-type lectin receptor signaling pathway
    109257574 (IL12B)
   04658 Th1 and Th2 cell differentiation
    109257574 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    109257574 (IL12B)
   05205 Proteoglycans in cancer
    109257574 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    109257574 (IL12B)
   05164 Influenza A
    109257574 (IL12B)
   05162 Measles
    109257574 (IL12B)
   05168 Herpes simplex virus 1 infection
    109257574 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    109257574 (IL12B)
   05134 Legionellosis
    109257574 (IL12B)
   05152 Tuberculosis
    109257574 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    109257574 (IL12B)
   05145 Toxoplasmosis
    109257574 (IL12B)
   05140 Leishmaniasis
    109257574 (IL12B)
   05142 Chagas disease
    109257574 (IL12B)
   05143 African trypanosomiasis
    109257574 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    109257574 (IL12B)
   05330 Allograft rejection
    109257574 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    109257574 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    109257574 (IL12B)
   04936 Alcoholic liver disease
    109257574 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ppad04052]
    109257574 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:ppad00536]
    109257574 (IL12B)
Cytokines and neuropeptides [BR:ppad04052]
 Cytokines
  Interleukins
   109257574 (IL12B)
Glycosaminoglycan binding proteins [BR:ppad00536]
 Heparan sulfate / Heparin
  Cytokines
   109257574 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_3 Ig_5 Ig_4 fn3 Ig_2 ig I-set IntS9_C DBD_Tnp_Mut
Other DBs
NCBI-GeneID: 109257574
NCBI-ProteinID: XP_019289307
Ensembl: ENSPPRG00000015059
UniProt: A0A9V1EUX1
LinkDB
Position
Unknown
AA seq 359 aa
METSRVRVNSRVAGAGLARPRSSALSRRPWMHPQQLVISWFSLVLLAPPLMAIWELEKNV
YVVELDWHPDAPGEMVVLTCNTPEEDDITWTSDQSSEVLGSGKTLTIQVKEFADAGQYTC
HKGGEVLSHLFLLIHKKEDGIWSTDILREQKESKNKIFLKCEAKNYSGRFTCWWLTAIST
DLKFTVKSSRGSSDPQGVTCGAATLSAEKVRVDNRDYKKYTVECQEGSACPAAEESLPIE
VVVDAIHKLKYENYTSSFFIRDIIKPDPPKNLQLKPLKNSRHVEVSWEYPDTWSTPHSYF
SLTFGVQVQGKNNREKKDRLSVDKTSAKVVCHKDAKIRVQARDRYYSSSWSNWASVSCS
NT seq 1080 nt   +upstreamnt  +downstreamnt
atggagacctcgcgggtgagagtgaactctcgggtcgccggcgcgggtctggcacggcct
cgcagcagcgccctctctcggcggccctggatgcatcctcagcagctggtcatctcctgg
ttttccctggttttgctggcacctcccctcatggccatatgggaactggagaaaaacgtt
tatgttgtagagttggactggcaccctgatgcccccggagaaatggtggtcctcacctgc
aatactcctgaagaagatgacatcacctggacctctgaccagagcagtgaagtcctaggc
tctggtaaaactctgaccatccaagtcaaagaatttgcagatgctggccagtatacctgt
cataaaggaggcgaggttctgagccatttgttcctcctgatacacaaaaaggaagatgga
atttggtccactgatatcttaagggaacagaaagaatccaaaaataagatctttctaaaa
tgtgaggcaaagaattattctggacgtttcacctgctggtggctgacggcaatcagtacc
gatttgaaattcactgtcaaaagcagcagaggctcctctgacccccaaggggtgacttgt
ggagcagcgacactctcagcagagaaggtcagagtggacaacagggattataagaagtac
acagtggagtgtcaggaaggcagtgcctgcccggctgccgaggagagcctacccattgaa
gtcgtggtggacgctattcacaagctcaagtacgaaaactacaccagcagcttcttcatc
agggacatcatcaaaccagacccgcccaagaacctgcaactgaagccattaaaaaattct
cggcatgtggaagtgagctgggaataccctgacacctggagcaccccacattcctacttc
tccttaacatttggcgtacaggtccagggcaagaacaacagagaaaagaaagatagactc
tccgtggacaagacctcagccaaggtcgtgtgccacaaggatgccaagatccgcgtgcaa
gccagagaccgctactatagctcatcctggagcaactgggcatccgtgtcctgcagttag

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