KEGG   Panthera pardus (leopard): 109257874
Entry
109257874         CDS       T06062                                 
Symbol
WNK2
Name
(RefSeq) serine/threonine-protein kinase WNK2
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
ppad  Panthera pardus (leopard)
Pathway
ppad04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:ppad00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    109257874 (WNK2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:ppad01001]
    109257874 (WNK2)
   01009 Protein phosphatases and associated proteins [BR:ppad01009]
    109257874 (WNK2)
Enzymes [BR:ppad01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     109257874 (WNK2)
Protein kinases [BR:ppad01001]
 Serine/threonine kinases: Other
  Wnk family
   109257874 (WNK2)
Protein phosphatases and associated proteins [BR:ppad01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     109257874 (WNK2)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C Pkinase_fungal
Other DBs
NCBI-GeneID: 109257874
NCBI-ProteinID: XP_019289817
LinkDB
Position
Unknown
AA seq 2068 aa
PGSPADPGPEPAGAQEPGPDPAPAPPGEPREDEAAAAAAAAGREDAAAPEARPEPGRARR
GEPEEEEDDEDLKAVATSLDGRFLKFDIELGRGSFKTVYKGLDTETWVEVAWCELQDRKL
TKLERQRFKEEAEMLKGLQHPNIVRFYDFWESSARGKRCIVLVTELMTSGTLKTYLKRFK
VMKPKVLRSWCRQILKGLLFLHTRTPPIIHRDLKCDNIFITGPTGSVKIGDLGLATLKRA
SFAKSVIGTPEFMAPEMYEEHYDESVDVYAFGMCMLEMATSEYPYSECQNAAQIYRKVTC
GIKPASFEKVHDPEIKEIIGECICKNKEERYEIKDLLSHAFFAEDTGVRVELAEEDHGRK
SSIALRLWVEDPKKLKGKPKDNGAIEFTFDLEKETPDGVAQEMIESGFFHESDVKIVAKS
IRDRVALIQWRRERIWPALQPPEQRDPGSPDKARGPPAPLQVQVTYHAKAGPPEPEEPEA
DQHLLPAALPASATSLASDSTFDSGQGSTVYSDSQSSQQSAVLGSLADAAPPPTQCVCSP
PVSASDGPVLPYSLPSLGPYQQPAVPGLPGSSIPPPARPPLPQQHFPEPAISFAPVSTGP
GQPVPAGQQPPPLAQPAPLPPVLAPPPVGPLQPVPPHLPPYLAPTSQVVAPAQLKPLQMP
PAPLQPLPQVPAQVPPLPVGPPIAPLASMDSLSTALPDLPAATGPAVPSVPAPSQYFSPA
VILPSLPLSAAAAPLPASPALPLQAVKLPHPTGAPLAVPCRTIVPNVAATATAIPLLAVA
PQGVAALSIHPAAVAQLPAQPVYPAAFPQMVPGDVPPSPLHAAQNVRAAPSQPAPPTLPQ
PHQPSVTHLPEQAAAAGGAGSQILLGHPPPYAVDVTAQVPTAPVPAAILSPPLPEVLPPP
VPELPQLPSSLAPVVVAASQNLPVQTTPLLPPTAHPTLEEQSSQEKQPSAPQSCDSYGGS
DVPSGREMSDSCEGAFGGGRLEGRAARKHHRRSTRARSRQERASRPRLTILNVCNTGDKM
VECQLETHNHKMVTFKFDLDGDAPDEIATYMVEHDFILQAERETFIEQMKDVMDKAEDML
SEDTDVDRGSDPGVSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEH
PAAEAPEPSPPLPLSSVQPEASQDTAPCKDQLSLKEKSGFPASPQHLSQTGPRDTPGGAP
APLLPSSPPVTALPQDAATPAASPKPEPSVGTAVQAGGPGTSQGMASERETPQPLAETQD
TQLSAQPLGAGGGPCAPPLEAPRYPSGLGEPTSAREAMAQGEPLQAPAPAPSAPSGTPQP
TLGQPLPPLPPAVGAISLATPQLPSPPLGPTGAPQPPSALESDGEGPPPRVGFVDSTIKS
LDEKLRTLLYQEHVPTSSASAGTPVEAGDRDLTLEPQPVPGKSETAPGLGAALEQAGSSP
LTAESSLSQVTTSGLPPAPGAPQDAPASAFPALLEPADQSSGVPGETSARPTPGMQTEDS
RASHLQTQGTLAAGSPQKHPGQQDGSSPAKTVGRFSVVSTQDEWTLGSPHSLRYSAPPDV
YLEEAPHSPDMKLAVRRAQTASSIEVGVGEPVSSDSGDEGPRRRPPVQKHASLPSSSGVA
SDFVKKATAFLHRSPRAGSPGPETPGRVGVKVPTISVTSFHSQSSYISSDNDSEIEDADI
RKELQSLREKHLKEISELQSQQKQEIEALYRRLGKPLPPNLGLFHTAPPAGRRRKSRSKL
KAGKLLNPLVQQLKVVASSTGHLSDCSRAPPAKDPAQAGAGPEAASDPCGKAVQTQQPCS
VRASLSADICSGLATDGGGAHGSGWTVYHPTSERLTYKSSSKPRARFLSGPVSVSIWSAL
KRLCLGKEHSSRSSTSSLVPGPEPGPQPTLHVQAQANNSNNKRGTFTDDLHKLVDDWTSK
TVGTTQLKPSLNQLKQTQRLHGMEAPAGWSPATGETRAMNASRAAVGTPCLAPAPSPLST
AAIPGTTPGLPMPVPWWRISCAWVLGVVEAAFLLCTPLSTAAPEILRVRSPTEPRQASPT
PTPGPVSSHVEKASLRLVSSSRCFVTTF
NT seq 6207 nt   +upstreamnt  +downstreamnt
cccggcagccccgccgaccccggccccgagcccgcgggcgcgcaggagcccggcccggac
cccgcgcccgcgccccccggagaaccccgcgaggacgaggcggcggcggcggcggcggcg
gcggggcgggaggacgcggcggcgccggaggcgaggcccgagccagggcgcgcccgccgg
ggagagcccgaggaggaggaggacgacgaggacctcaaggccgtggccacctcgctggac
ggccgcttcctcaagttcgacatcgaactgggccgcggctcattcaagacggtctacaag
gggctggacacggagacctgggtggaggtggcctggtgcgagctgcaggaccggaagctc
accaagctggagaggcagcggttcaaagaggaggccgagatgctcaagggcctgcagcac
cccaacatcgtgcgcttctatgacttctgggagtccagtgccagggggaagaggtgcatc
gtgctggtgaccgagctgatgacctcggggacgctgaagacgtacctgaagcggttcaag
gtgatgaagcccaaggtcctgcgcagctggtgccggcagatcctgaaggggctgctgttc
ctgcacaccaggacgccccccatcatccaccgggacctcaagtgtgacaacatcttcatc
actgggcccaccggctctgtgaagatcggcgacttgggcctggccactctcaagagggcg
tcctttgccaagagcgtgatcggcaccccagagttcatggcgcccgagatgtacgaggag
cattacgacgagtctgtggacgtctatgccttcggcatgtgcatgctggagatggccacc
tcagagtacccctactccgagtgccagaatgcagcccagatctaccggaaggtcacctgt
ggcatcaaacctgccagctttgagaaagtgcatgatcctgaaatcaaggagatcatcggg
gaatgcatctgcaaaaacaaggaggaaaggtacgagatcaaggacctgctgagccacgcc
ttcttcgcggaggacacgggagtgagggtggagctggcagaggaggaccacggcaggaag
tctagcatcgccctgcggctctgggttgaggaccccaagaaactgaagggcaagcccaag
gacaacggggccatagagttcacctttgacctggagaaggagacgccggatggtgtggcg
caggagatgatcgagtcgggattcttccacgagagcgacgtgaagattgtggccaagtcc
atccgcgaccgagtagcattgatccagtggcggcgagagaggatctggccggcgctgcag
cccccggagcagcgggacccaggcagccccgacaaggccaggggcccgcccgcacccctg
caggtccaggtgacctaccacgccaaggctgggccgccggagcccgaggaacccgaggca
gaccagcacctcctgcctgccgcgctgccggccagcgccacctccctggcctcggatagc
acgttcgacagcggccagggctccaccgtgtactcggactctcagagcagccagcagagt
gcggtgctgggctcgctggcggacgcggccccgcccccgactcagtgcgtgtgcagtccc
ccggtgagcgcgagtgacgggcctgtcctgccgtacagcctgccctcgctggggccctac
cagcagcctgccgtgcctggactgcctgggagctccatcccgcccccagcccgccctccg
ctcccgcagcagcatttcccggagccagccataagttttgctcccgtgtcgacgggcccg
ggccagcctgtgcctgctggccagcagcctcctccactggcccagccggcgcccttgccc
cctgtcctggccccaccgcccgtgggccccctccagccggtgccccctcatctgccgccc
tacctagctccgacttcccaggtggtggcccccgctcagctgaagcccctccagatgccg
ccagcacctctgcagcctctgcctcaggtgcctgctcaggtgcctccgcttcccgtcggg
ccgcccattgcgcccctggcctccatggacagcctctccacagctctgcccgacctgccg
gccgccaccgggcccgccgtcccctccgtccccgctccctctcagtatttctctcccgcc
gtcatcttgccaagcctcccgctcagcgccgccgccgcccccctgcccgcgtcaccagcc
ctgcccctgcaggcggtcaagctgccccaccccaccggggcgccgctcgccgtgccgtgc
cggaccattgtgccaaacgtggcggccaccgccaccgccatccctctgctggccgtggcc
ccgcagggtgtggccgccctgtccattcacccggccgctgtggctcagctcccggcccag
cccgtgtacccggcagcctttccgcagatggtgcccggcgacgtcccgccttctcccctc
cacgcggcgcagaacgtgcgggctgccccgtcccagcctgcgccccccacgctgccgcag
ccccaccagccaagcgtcacacaccttccagagcaggccgctgcggcaggtggggcgggg
agccagatcttgcttggccacccgcctccatacgctgtggatgtcaccgcccaggtcccc
acggcacccgtgccagccgccatcctctccccacctctgcccgaagtgttgccgcctcct
gtccccgagctgcctcagctccccagctccctggcccccgtggtggtggcggcctctcag
aacttgcctgtccagaccacgccgctcctgccgcccaccgcccacccnaccctggaagag
cagtcctctcaggagaagcagcccagcgccccgcagagctgtgacagctacggaggctcc
gacgttccctctggaagagagatgagcgacagctgtgagggtgcatttggtggtgggagg
ctggagggcagggccgcccggaaacatcaccgccggtccacgcgtgcgcgctcccgccag
gagagagccagccgcccccggctcaccatcctgaacgtgtgcaacacgggcgacaagatg
gtggagtgccagctggagacgcacaatcacaagatggtgacgttcaagtttgacctagac
ggggacgcgcctgacgagatcgccacctatatggtggagcacgacttcatcctgcaggcc
gagcgagagacgttcatcgagcagatgaaggacgtcatggacaaggcggaggatatgctc
agtgaggacacggacgtcgaccggggctccgaccccggggtcagcccgccacacctcagc
acctgcggcctgggcactggggaggagagtcgccagtcccaagcaaacgcccccgtgtat
cagcagaacgttctgcacacgggcaagaggtggtttatcatctgcccggtggctgagcac
ccagcggcggaggcccctgagccttcaccgccacttcctctgagctccgtgcagccagaa
gccagccaagacacagcgccctgtaaagaccagctgtccttaaaggaaaaatccggcttc
ccagccagtccacagcatctgagccaaacaggccccagggacacccctggcggtgcaccg
gcccctttgctgccatcctcccctcctgtgactgctctgccccaggatgcggccacccca
gccgccagccccaagccagagccctcagtggggactgctgtgcaggcagggggcccaggg
acctctcaggggatggccagtgagcgtgagaccccccagccactggcagagactcaagac
acccagctttctgcacaacccctgggtgcaggtggggggccttgtgccccacctctggag
gccccccgctacccctcgggtttgggagagcccacctcagccagggaggccatggcccag
ggtgagcccttgcaggctccggcccctgcacccagtgcccccagtgggacccctcagccc
accctgggtcagcccctacccccgttgccccctgcagtaggggccatcagcctggccact
ccccagctccccagccccccactggggcccactggggccccccagccaccctcggccttg
gagtcagatggggaggggcctccccccagggtgggctttgtggacagcaccatcaagagc
ctagatgagaagcttcgaactctgctctaccaggagcacgtgcccacctcctcagcctct
gctgggacccctgtggaggcgggggaccgagacttgaccctggagccccagcccgtgccg
ggaaagtcagaaacagcccctgggctgggggctgcattggagcaggctgggtcctcgcca
ttgacagcagaatcatctttgagccaagtgacaacctcaggtttgcccccggcgccaggt
gccccccaggatgcccctgcttctgccttccctgcactcctggagcccgcagaccagagc
agtggggtcccgggggaaacttcagccaggcccacaccggggatgcagacggaagacagc
cgggccagccacctgcagacgcagggcactctggccgcagggtccccacagaagcatcca
gggcagcaggacggcagctcaccagccaaaactgtgggccggttctccgtggtcagcacg
caggacgagtggaccctgggctccccccacagcctgcggtactcggcgccgccagacgtg
tacctggaggaggccccccacagccccgacatgaagctggccgtgcggagggcgcagaca
gcctcctccattgaggtcggcgtgggcgagccggtgtccagcgactccggggacgagggt
ccgcgcaggcggccccctgtgcagaagcacgcctccctacccagcagcagtggcgtggcc
agcgacttcgtgaagaaggccaccgccttcctgcacaggtccccacgggctggctccccg
ggcccagagacgcccggcagggtgggcgtgaaggtgcccaccatcagtgtgacctccttc
cactcccagtcgtcctacatcagcagcgacaacgactcggagatcgaggacgccgatatc
aggaaggagctgcagagtctgcgggagaagcacctgaaggagatctcggagctgcagagc
cagcagaagcaggagatcgaggccctgtaccgccgcctgggcaagccgctgccccccaac
ctgggcctcttccacacggcccctcccgccggccgcaggaggaagagcaggagcaagctg
aaggcagggaagctgctcaacccgctggtgcagcagctcaaggtcgtggcctccagcaca
ggtcacttgtcagactgcagcagagcccctcctgctaaggaccctgcccaagccggggca
gggcccgaagcagcttcagacccgtgtgggaaggcagttcagacccagcagccttgctcg
gtgcgggcctccctgtctgcagacatctgctccggcttagccactgacggaggcggagcg
catggctcaggctggacggtttaccacccaacgtctgagagactgacctataagtctagt
agcaaacctcgcgctcgattcctcagtggacccgtgtctgtgtccatctggtctgccctg
aagcgtctctgtctaggcaaagagcacagcagtcggtcttccaccagcagcctggtcccg
ggccctgagccgggcccccagcccaccttgcacgtccaggcacaggcgaacaacagcaac
aacaagagaggcaccttcacggatgacctgcacaagctggtggacgactggacgagcaag
acggtggggaccacccagctgaagccctcgctcaaccagctgaagcagactcagaggcta
cacggcatggaggccccggcgggctggtccccagccactggcgagacacgggctatgaac
gcctctcgagcagcagtggggacaccatgtctggccccagcgcccagccctctatccacc
gcggccattcctggaaccaccccaggcctgcccatgccagtcccttggtggagaatctcg
tgcgcctgggtcctgggggtggtggaagctgcctttctcctatgcacccccctctccact
gctgcaccagagattctgagagtgagaagcccgactgagcccaggcaggccagcccgacc
ccgacgccaggccctgtgtcgtcacacgtggagaaggcgagtctgcgcctcgtgtccagt
tcacgctgttttgtaaccactttctaa

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