Panthera pardus (leopard): 109276095
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Entry
109276095 CDS
T06062
Symbol
PTPN6
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 6 isoform X1
KO
K05697
tyrosine-protein phosphatase non-receptor type 6 [EC:
3.1.3.48
]
Organism
ppad
Panthera pardus (leopard)
Pathway
ppad04148
Efferocytosis
ppad04520
Adherens junction
ppad04630
JAK-STAT signaling pathway
ppad04650
Natural killer cell mediated cytotoxicity
ppad04660
T cell receptor signaling pathway
ppad04662
B cell receptor signaling pathway
ppad05140
Leishmaniasis
ppad05205
Proteoglycans in cancer
ppad05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ppad00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
109276095 (PTPN6)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
109276095 (PTPN6)
09144 Cellular community - eukaryotes
04520 Adherens junction
109276095 (PTPN6)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
109276095 (PTPN6)
04660 T cell receptor signaling pathway
109276095 (PTPN6)
04662 B cell receptor signaling pathway
109276095 (PTPN6)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
109276095 (PTPN6)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
109276095 (PTPN6)
09174 Infectious disease: parasitic
05140 Leishmaniasis
109276095 (PTPN6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
ppad01009
]
109276095 (PTPN6)
Enzymes [BR:
ppad01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
109276095 (PTPN6)
Protein phosphatases and associated proteins [BR:
ppad01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
109276095 (PTPN6)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
DSPc
PTPlike_phytase
Y_phosphatase3
HGAL
Motif
Other DBs
NCBI-GeneID:
109276095
NCBI-ProteinID:
XP_019320196
UniProt:
A0A9V1GDI6
LinkDB
All DBs
Position
Unknown
AA seq
597 aa
AA seq
DB search
MLSGGWFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSG
DFYDLYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLNCSDPTSERWYHGHMSGG
QAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTHIKVMCEGGRYTV
GGSETFDSLTDLVEHFKKTGIEEASGAFVYLRQPYYATRVNAADIENRVLELNKKQESED
TAKAGFWEEFESLQKQEVKNLHQRLEGQRPENKSKNRYKNILPFDHTRVILQGRDSNIPG
SDYINANYVKNQLLSPDENAKTYIASQGCLEATVNDFWQMAWQENTRVIVMTTREVEKGR
NKCVPYWPEVGAQRVYGPYTVTNCGEHDTAEYKLRTLQVSPLDNGDLVREIWHYQYLSWP
DHGVPSEPGGVLSFLDQINQRQESLPHAGPIIVHCSAGIGRTGTIIVIDMLMESISTKGL
DCDIDIQKTIQMVRAQRSGMVQTEAQYKFIYVAIAQFIETTKKKLEVIQSQKGRESEYGN
ITYPLAMKNAHAKASRTSSKHKEDVYENLHSKNKKEDKVKKQRSADKEKSKGSLKRK
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgctgtccggtgggtggtttcaccgagacctcagtgggctggatgcagagacgctgctc
aagggccgcggggtccatgggagcttcttggctcggcccagtcgcaagaaccagggcgac
ttctccctctccgtcagggtcggggatcaggtgacccacattcggatccagaactcggga
gatttctatgacctgtacggaggggagaagtttgcgacactgacggagctggtggagtac
tacacacagcagcagggtgtcctacaggaccgggatggcaccatcatccacctcaagtac
ccgctgaactgctccgaccccaccagcgagaggtggtaccacggtcacatgtctgggggg
caggcagagacactgctgcaggccaagggtgagccctggacgtttctcgtgcgtgagagt
ctcagccagcctggagattttgtgctgtccgtgctcagcgaccagcccaaggctggccca
ggctccccactcagagtcactcatatcaaggtcatgtgtgagggtggacgctacacggtg
ggtggctcagagacctttgacagcctcacagacctggtggagcatttcaagaagacgggg
attgaggaggcctcgggtgccttcgtctacctgcggcagccgtactatgccactcgggtg
aacgcagctgacattgagaatcgggtgttggaactcaacaagaagcaggagtcagaggac
acagccaaagccggcttttgggaggagtttgagagtctgcagaagcaggaggtaaagaac
ttgcaccagcggctggaaggccagaggccagagaacaagagcaagaaccgttacaagaac
attcttccgttcgaccacacccgagtgatcctgcagggacgtgacagcaacatccctggg
tccgactatatcaatgccaactacgtcaagaaccagctgctaagccccgatgagaacgct
aagacctacatcgccagccagggctgcctggaggccacagtcaacgacttctggcagatg
gcatggcaggagaacacccgagtcattgtcatgaccacccgagaggtggagaaaggccgg
aacaaatgtgtgccatattggccagaggtgggcgctcagcgcgtttatggaccgtacaca
gtaaccaattgcggggagcatgacacagctgagtacaaactccgtaccttgcaggtctcc
ccgctggacaatggggacctggttcgggagatctggcactatcagtacctgagctggcct
gaccatggcgtccccagcgagcctgggggtgtcctcagcttcctggatcagatcaaccag
cggcaggagagtctgcctcacgcgggacccatcatcgtgcactgcagcgcaggcattggc
cgcacaggcaccatcatcgtcatcgacatgctcatggaaagcatctccaccaaggggttg
gactgtgacatcgacatccagaagaccatccagatggtgcgggcgcagcgctccggcatg
gtgcagactgaggcgcagtacaagttcatctatgtggccatcgcccagttcattgaaacc
accaagaagaagctggaggtcattcagtcccagaagggccgggagtcagagtacgggaac
atcacctaccccttagccatgaagaacgcccatgccaaggcatcccgcacctcttccaaa
cacaaggaggatgtatatgagaacttgcacagtaagaacaagaaggaggacaaggtgaag
aagcagcggtcggcggacaaggagaagagcaagggttccctcaagaggaaatga
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integrated database retrieval system
