Phocoena phocoena (harbor porpoise): 136130405
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Entry
136130405 CDS
T11058
Symbol
CACNA1S
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1S
KO
K04857
voltage-dependent calcium channel L type alpha-1S
Organism
pphc Phocoena phocoena (harbor porpoise)
Pathway
pphc04010
MAPK signaling pathway
pphc04020
Calcium signaling pathway
pphc04022
cGMP-PKG signaling pathway
pphc04024
cAMP signaling pathway
pphc04260
Cardiac muscle contraction
pphc04261
Adrenergic signaling in cardiomyocytes
pphc04270
Vascular smooth muscle contraction
pphc04723
Retrograde endocannabinoid signaling
pphc04725
Cholinergic synapse
pphc04726
Serotonergic synapse
pphc04727
GABAergic synapse
pphc04911
Insulin secretion
pphc04912
GnRH signaling pathway
pphc04921
Oxytocin signaling pathway
pphc04924
Renin secretion
pphc04925
Aldosterone synthesis and secretion
pphc04927
Cortisol synthesis and secretion
pphc04929
GnRH secretion
pphc04934
Cushing syndrome
pphc04935
Growth hormone synthesis, secretion and action
pphc05010
Alzheimer disease
pphc05020
Prion disease
pphc05022
Pathways of neurodegeneration - multiple diseases
pphc05207
Chemical carcinogenesis - receptor activation
pphc05410
Hypertrophic cardiomyopathy
pphc05412
Arrhythmogenic right ventricular cardiomyopathy
pphc05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pphc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
136130405 (CACNA1S)
04020 Calcium signaling pathway
136130405 (CACNA1S)
04024 cAMP signaling pathway
136130405 (CACNA1S)
04022 cGMP-PKG signaling pathway
136130405 (CACNA1S)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
136130405 (CACNA1S)
04929 GnRH secretion
136130405 (CACNA1S)
04912 GnRH signaling pathway
136130405 (CACNA1S)
04921 Oxytocin signaling pathway
136130405 (CACNA1S)
04935 Growth hormone synthesis, secretion and action
136130405 (CACNA1S)
04924 Renin secretion
136130405 (CACNA1S)
04925 Aldosterone synthesis and secretion
136130405 (CACNA1S)
04927 Cortisol synthesis and secretion
136130405 (CACNA1S)
09153 Circulatory system
04260 Cardiac muscle contraction
136130405 (CACNA1S)
04261 Adrenergic signaling in cardiomyocytes
136130405 (CACNA1S)
04270 Vascular smooth muscle contraction
136130405 (CACNA1S)
09156 Nervous system
04727 GABAergic synapse
136130405 (CACNA1S)
04725 Cholinergic synapse
136130405 (CACNA1S)
04726 Serotonergic synapse
136130405 (CACNA1S)
04723 Retrograde endocannabinoid signaling
136130405 (CACNA1S)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
136130405 (CACNA1S)
09164 Neurodegenerative disease
05010 Alzheimer disease
136130405 (CACNA1S)
05020 Prion disease
136130405 (CACNA1S)
05022 Pathways of neurodegeneration - multiple diseases
136130405 (CACNA1S)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
136130405 (CACNA1S)
05412 Arrhythmogenic right ventricular cardiomyopathy
136130405 (CACNA1S)
05414 Dilated cardiomyopathy
136130405 (CACNA1S)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
136130405 (CACNA1S)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pphc04040
]
136130405 (CACNA1S)
Ion channels [BR:
pphc04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
136130405 (CACNA1S)
BRITE hierarchy
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ion_trans
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
136130405
NCBI-ProteinID:
XP_065742767
LinkDB
All DBs
Position
1:complement(185314779..185375475)
Genome browser
AA seq
1868 aa
AA seq
DB search
MEPSSPQDEGLRKKQPKKPVPEVLPRPPRALFCLTLQNPVRRACISIVEWRPFETIILLT
IFANCVALAAYLPMPEDDSSALNLGLEKLEYFFLIVFSIEAAMKIIAYGFLFHQDAYLRS
GWNVLDFIIVFLGVFTAILEQVNVIQTNTAPMSSKGAGLDVKALRAFRVLRPLRLVSGVP
SLQVVLNSVFKAMQPLFHIALLVLFMAIIYAIIGLELFKGKMHKTCYFIGTDIVATVENE
KPSPCARTGSGRRCTMNGSECRGGWPGPNHGITHFDSFGFSMLTVYQCITMEGWTDVLYW
VNDAIGNEWPWIYFVTLILLGSFFILNLVLGVLSGEFTKEREKAKSRGTFQKLREKQQLD
EDLRGYLSWITQGEVMDVDDLREGKLALDEGGSDTESLYEIAGLNKVIQFIRHWRRWNRV
FRWKCHDAVKSRVFYWLVILIVALNTLSIASEHHHQPLWLTHLQDSANRVLLALFTVEML
MKMYGLGLRQYFMSIFNRFDCFVVCSGLLEILLVESGAMTPLGISVLRCLRLLRIFKITK
HWTSLSNLVASLLNSIHCIASLLLLLSLFVVIFALLGMQLFGGRYDFEDTEVRRSNFDNF
PQALITVFQVLTAEDWNSVMYDGIMAYGGPTYPGVLVCIYFIILFVCGNYILLNVFLAIA
VDNLAEAESLTSAQKAKAEERRRRKMSRGLPDKSEEEKSTVAKKLEQKPKGEGIPTTAKL
KIDEFESNVNEVKDPYPSADFPGDDEEDEPEIPISPRPRPLAELQLKEKAVPIPEASAFF
IFSPTNKLRVLCHRIVNATWFTNFILLFILLSSAALAAEDPIRTESVRNQILGYFDIVFT
SVFTVEIVLKMTTYGAFLHKGSFCRNYFNILDLVVVAVSLISMGLESSTISVVKILRVLR
VLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVLVTTLLQFMFACIGVQLFKGKFFSCNDL
SKRTEEECRGYYYVYKDGDPTQMELRPRQWTHNNFHFDNVLSAMMSLFTVSTFEGWPELL
YRAIDSHKEDQGPVYNEHPEMAIFFIVYIILIAFFMMNIFVGFVIVTFQEQGETEYKNCE
LDKNQRQCVQYALKARPLKCYIPKNPCQYQVWYIVTSSYFEYLMFALIMLNTICLGMQHY
NQSEQMDHISDVLNVAFTTIFTVEMVLKLMAFKARGYFGDPWNVFDFLIVIGSIIDVILS
EIDTFLASSGGLYCLGGSCGNVDPDESARISSAFFRLFRVLRLIKLLSRAEGVRTLLWTF
IKSFQALPYVALLIVMLFFIYAVIGMQLLGKVALVDGTQINRNNNFQTFPQAVLLLFRCA
TGEAWQEILLACSYGQLCDPESDYAPGEERTCGTDFAYYYFISFYMLCAFLIINLFVAVI
MDNFDYLTRDWSILGPHHLDEFKAIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKFCP
HRVACKRLVGMNMPLNSDGTVTFNATLFALVRTALKIKTEGNFEQANEELRAIIKKIWKR
TSMKLLDQVIPPIGDDEVTVGKFYATFLIQEHFRKFMRRQEEYYGYRPKKDTVQIQAGLR
TLEEEAAPEIRRTISGDLTAEEELERAMVEAAMEEGIFRRTGGLFGQVDSFLERTNSLPP
HMANQRPLQFTEIEMQELESPVFLEDFPQHPSTNPLARANTNNANANVAGGNSNPGNSPA
FFSVHSEGELPGETETPASRGGASGRPQGTLGPHSKSHGERLQGQLPRRVIRGAQAPANP
CQLVGTQSLVPEERSPTPGSLPEEAPPKDGTPGCPAPAMALLIREALIRGGLDTLAADAK
FVMATGHTLVEACQMELQEVEVAAAELLKGRETPEGVASARGRWSLGSSLGSLDQHQGSQ
ETLIPRRL
NT seq
5607 nt
NT seq
+upstream
nt +downstream
nt
atggagccgtcctcgccccaggatgagggcctgaggaagaagcagcccaagaagccggtt
cccgaggtcctgcccaggccgccgcgggccttgttctgcttgactctccagaaccctgtg
aggagggcctgcatcagcatcgtggaatggagacccttcgagaccatcatcttactcacc
atctttgccaactgtgtggccctggccgcgtacctgcccatgccggaggacgacagcagc
gctctgaacctcggcctggagaagctggagtacttcttcctcatcgtcttctccattgag
gccgccatgaagatcattgcctacggcttcctgttccaccaggacgcctacctgcgcagc
ggctggaacgtgctggactttatcatcgtattcctgggggtcttcaccgcgattctggag
caggtcaacgtcatccagaccaacacagccccgatgagcagcaaaggcgccggcttggac
gtcaaggctctgagggccttccgcgtgctcagaccgctccggctggtgtccggggtgccc
agcctgcaggtggtcctcaactccgtcttcaaggccatgcagcccctgttccacatcgcc
ctgcttgtactcttcatggccatcatctacgccatcatcgggctggagctcttcaagggc
aagatgcacaagacctgctacttcatcgggacggacatcgtggccacggtggagaacgag
aagccgtcgccctgcgcccggacggggtcagggcgccgctgcaccatgaacggcagcgag
tgccggggcggctggccaggccccaaccacggcatcacccacttcgacagcttcggcttc
tccatgctcaccgtgtaccagtgcatcaccatggagggctggaccgacgtcctctactgg
gtcaacgatgccattgggaacgagtggccctggatctactttgtcaccctgatcctgctg
ggctccttcttcatcctcaacttggtgctgggcgtcctgagcggggaattcaccaaggag
cgggagaaggccaagtccaggggaaccttccagaagctgcgggagaagcagcagctggat
gaggacctccggggctacttgagctggatcacgcagggcgaggtcatggatgtggacgac
ttgagagaagggaagctggctttggatgaaggtggctctgacacagagagcctgtatgaa
atcgcaggcttgaacaaagtcatccagttcatccgacactggaggcggtggaaccgcgtc
ttccgctggaagtgccacgacgcggtgaagtccagggtcttctactggctggtcatcctg
atcgtcgccctcaacaccctgtcgatcgcctcggaacaccaccaccagcctctctggttg
acccacctgcaagacagcgccaaccgggtgctgctggccctgttcaccgtggagatgttg
atgaagatgtatgggctgggcctgcgccagtacttcatgtccatcttcaaccgcttcgac
tgcttcgtggtgtgtagcggcctcctggagatcctgctggtggagtcgggggccatgaca
cccctcggcatctccgtcctgcgctgcctccgccttctcaggattttcaagatcaccaag
cactggacgtccctgagcaacctggtggcctcgctgctgaactccatccactgcatcgcg
tccctgctgctgctgctgtccctgttcgtcgtcatcttcgccctcctgggcatgcagctc
ttcgggggcaggtacgactttgaggacacggaggtgcggcgcagcaacttcgacaacttc
ccgcaggccctcatcaccgtcttccaggtgctgacagctgaggactggaactccgtgatg
tatgacgggatcatggcctacggcggcccgacctaccccggggtgctcgtctgcatctat
ttcatcatcctgttcgtctgtggcaactacatactgctcaacgtcttcctggccatcgcg
gtagacaacctggcggaggcggagagcctgacgtcggcccaaaaggccaaggccgaggag
cggaggcgcaggaagatgtccagggggctcccagacaagtcagaggaggagaagtcgacg
gtggccaagaagctggagcagaaacccaagggggagggcatccccaccacggccaagctg
aaaatcgatgagtttgaatccaatgtcaatgaggtgaaggacccctacccgtcagccgac
ttcccaggagatgatgaggaagacgaacccgagatccccataagcccacgaccccgcccg
ctggctgagctgcagctgaaggagaaggccgtgcccattccagaagccagcgccttcttt
atcttcagccccaccaataagctccgcgtcctgtgccatcgcatcgtcaacgccacctgg
ttcaccaacttcatcctgctcttcatcctgctcagcagtgccgcgctggctgctgaggac
cccatccggaccgagtccgtgaggaaccagatccttgggtattttgacatcgtgttcacc
tctgtcttcactgtggagattgtcctcaagatgaccacctatggggccttcctgcacaag
ggctccttctgccgcaactacttcaacatcctggacctggtggtggtggccgtgtccctc
atctccatgggactcgagtctagcaccatctccgtggtgaaaatcctgagggtactgagg
gtactccgaccgctccgggccatcaacagagccaaagggctgaagcacgtggtgcagtgc
gtgttcgtggccatccgcaccatcgggaacatcgtcctggtcaccaccctcctgcagttc
atgttcgcctgcatcggcgtccagctcttcaaggggaaattcttcagctgcaatgacttg
tccaagaggacagaggaggagtgcaggggctactactacgtgtacaaggatggggacccc
acgcagatggagctgcgtccccgccagtggacacacaacaacttccacttcgacaacgtg
ctctcggccatgatgtcactcttcacggtgtccaccttcgaggggtggccggagctgctg
tacagagccattgactctcacaaggaggaccagggccccgtgtacaacgagcacccggag
atggccatcttcttcatcgtctacatcatcctcatcgccttcttcatgatgaacatcttc
gtgggcttcgtcatcgtcaccttccaggagcagggggagaccgagtacaagaactgcgag
ctggacaagaaccagcgccagtgcgtgcagtacgccctgaaggcccgccccctgaagtgc
tacatccccaaaaacccgtgccagtaccaggtgtggtacatcgtcacctcctcctacttc
gagtacctaatgttcgccctcattatgctcaacaccatctgcctgggcatgcagcattac
aaccagtcggagcagatggaccacatctcagacgtcctcaacgtggccttcaccaccatc
ttcacggtggagatggtcctcaagctcatggccttcaaggccaggggctattttggggac
ccctggaatgtgtttgacttcctgattgtcatcggcagcatcatcgacgtcatcctcagt
gagattgacactttcctggcctccagcgggggactgtattgcctgggtggcagctgcggg
aacgttgaccccgacgagagcgcccgcatctccagcgccttcttccgcctgttccgcgtc
ctgaggctgatcaagctgctgagccgcgcggagggcgtgcgcacgctgctctggaccttc
atcaagtccttccaggccctgccctacgtggctctgctcatcgtcatgctcttctttatc
tacgccgtcatcggcatgcagctgctcgggaaggtcgccctggtggacgggacccagatc
aaccggaacaacaacttccagaccttcccccaggccgtgcttctgctgttcaggtgtgcc
acgggtgaggcgtggcaggagatcctgctggcctgcagctacggccagctatgcgacccc
gagtcggactacgccccgggggaggagcgcacctgtggcaccgacttcgcctactactac
ttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgtggctgtcatc
atggacaactttgactacctcacacgggactggtccatcctgggccctcatcacctggac
gaattcaaggccatctgggcagagtatgacccagaggctaagggcagaatcaagcacctg
gacgtggtgaccctgctgagaaggatccagccccctctgggctttgggaagttctgccca
caccgggtagcatgtaagcggctggtgggcatgaacatgcccctgaacagcgacggcaca
gtcaccttcaacgccactctcttcgccctggtccgcacggcactcaagatcaagacggaa
ggtaacttcgaacaggccaacgaggagctgcgggccatcatcaagaagatctggaagagg
accagcatgaagctcctggaccaggtcatccctcccataggagatgacgaggtgacggtg
gggaagttctacgccacatttctcatccaggagcacttccggaagttcatgaggcgccag
gaggaatattatgggtaccggcccaagaaggacaccgtgcagatccaggccggactgcgg
acccttgaggaagaggcagcccctgagatccgccgcaccatctccggagacctgacggcc
gaggaagagctggagagagccatggtggaggccgcgatggaggaagggatattccggagg
accggaggcctgtttggccaggtggacagcttcctggaaaggaccaactccctgcctcca
cacatggccaaccagagacccctccagtttactgaaatagagatgcaggagctggagtca
cccgtcttcttggaggacttccctcagcatccaagcaccaacccccttgcccgtgccaac
accaacaatgccaacgccaacgttgccggtggcaacagcaaccctggcaacagcccggca
tttttcagcgtccactctgaaggggagctcccaggggagacagagacgcctgccagcaga
ggaggagcttccggccggccccaggggaccctgggaccccacagcaagtcccatggggag
aggctgcagggacagctgccccggagggtgatacgcggagctcaggcacctgccaacccc
tgccagcttgtggggacacagtctctggtgcccgaggagaggagccccaccccagggtcc
ctgcccgaggaagcgccccccaaggatggtacccccgggtgcccggccccagccatggcc
ctgctgatccgagaggctctgattcgagggggcctggacaccttggcggctgatgctaag
ttcgtcatggcaacgggccacaccctggtggaagcctgccagatggaactgcaggaagtg
gaggtggcagccgccgagcttctgaagggacgagagaccccggagggtgtggccagtgcc
cgggggcgttggagcctcgggtcctccctgggaagcctcgaccagcatcagggctcccag
gagaccctcattccccgcaggctgtga
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integrated database retrieval system
