KEGG   Phocoena phocoena (harbor porpoise): 136133924
Entry
136133924         CDS       T11058                                 
Symbol
CAD
Name
(RefSeq) multifunctional protein CAD isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
pphc  Phocoena phocoena (harbor porpoise)
Pathway
pphc00220  Arginine biosynthesis
pphc00240  Pyrimidine metabolism
pphc00250  Alanine, aspartate and glutamate metabolism
pphc01100  Metabolic pathways
pphc01240  Biosynthesis of cofactors
Module
pphc_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:pphc00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    136133924 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    136133924 (CAD)
   00220 Arginine biosynthesis
    136133924 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pphc01002]
    136133924 (CAD)
Enzymes [BR:pphc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     136133924 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     136133924 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     136133924 (CAD)
Peptidases and inhibitors [BR:pphc01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   136133924 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   136133924 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 GARS_A Peptidase_C26
Other DBs
NCBI-GeneID: 136133924
NCBI-ProteinID: XP_065747424
LinkDB
Position
14:complement(68946250..68968867)
AA seq 2225 aa
MAALVLEDGSVLRGQPFGAAVSTAGEVVFQTGMVGYPEALTDPSYKAQILVLTYPLIGNY
GIPPDEVDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSATCTLHEWLQQRGIPGLQGVD
TRELTKKLREQGSLLGKLVQDGTEPSTLPFLDPNARALVPEVSIKVPRVFNSGGTPRILA
LDCGLKYNQIRCLCQRGAEVTVVPWDHALESQEYEGLFLSNGPGDPASYPSVVSTLSRVL
SEPNPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLVGSGRCFLTSQNHGFAVE
TDSLPASWLPLFTNANDHSNEGIVHESLPFFSVQFHPEHQAGPSDMEILFDIFLDTVKEA
TTRNPGGQTVRERLAERLCLPGIPTPGSGLPPPRKVLILGSGGLSIGQAGEFDYSGSQAI
KALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQVIRNERPDGVLLTFGGQT
ALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMAEIGEHVAPSEAANSLEQ
AQAAAERLGYPVLVRAAFALGGLGSGFASNKEELSALVAPAFAHTSQVLVDKSLKGWKEI
EYEVVRDTYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDREYQLLRQTAIKVTQHLG
IVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPELRN
SVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVGEVMGIGRSFEEAFQKAL
RMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSVDRLYELTRIDRWFLHRM
KGIVAHTQLLEQHRGQSLPLPLLQQAKRLGFSDKQIALAVLSTELAVRKLRQELGICPAV
KQIDTVAAEWPAQTNYLYLTYWGTTHDLSFRTPHVLVLGSGVYRIGSSVEFDWCAVGCIQ
QLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGVILSMGGQLP
NNMAMALHRQQCRVLGTCPEAIDSAENRFKFSRLLDTIGISQPQWRELSDLESARQFCQT
VGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPVVISKFIQEAKEIDVDAV
ACDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIKAIVHAVGQELQVTGPFN
LQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIMGEEVEPVGLMTGSGVVG
VKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAMLSTGFKIPKKNILLTIG
SYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVDWHFEEAVDGECPPQRSI
LEQLAEKNFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFSVPLIIDIKCTKLFVEAL
GQIGPAPPLKVHVDCMTSQKLVRLPGLIDVHVHLREPGGTHKEDFASGTAAALAGGITMV
CAMPNTWPPIIDAPALALAQKLAEAGARCDYTLFLGASSENAGTLGAVAGSAAGLKLYLN
ETFSELRLDSVAQWMEHFETWPSHLPIVAHAERQSVAAVLMVAQLTQRSVHICHVARKEE
ILLIKAAKARGLPVTCEVAPHHLFLSRDDLERLGPGKGEVRPELGSRQDVEALWENMAVI
DCFASDHAPHTVDEKCGPQPPPGFPGLETMLPLLLTAVSEGRLSLDDLLQRLHHNPRRIF
HLPPQEDTYVEVDLEHEWTVPNHMPFSKAHWTPFEGQKVKGTVRRVVLRGEVAYIDGQVL
VPPGYGQDVRKWPQGAVPQLTPSAPAASELNTTPERPRRGIPALPDGRFHLPPRIHRASD
PGLPAEEPKEKTSRKAAEPELMGTLDGTCYPPPPVPRQASPQNLGTPGLLHPQTSPLLHS
LVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEVSTRTSSSF
AAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVLRHPQPGAVELAAKHCRR
PVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKHGRTVHSLACLLTQYRVS
LRYVAPPSLRMPPDVRAFVASRGTKQEEFESIEEALPDTDVLYMTRIQKERFGSSQEYEA
CFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAYFRQAENGMYIRMALLAT
VLGRF
NT seq 6678 nt   +upstreamnt  +downstreamnt
atggcggccctggtgttggaggacgggtcggtcctgcggggccagccctttggggccgct
gtgtcgactgccggggaagtggtgtttcaaaccggtatggtcggctaccccgaggccctc
actgacccttcctacaaagcacagatcttagtgctgacatatcctctgattggtaactac
ggcattcccccagatgaagtggatgagttcgggctcagcaagtggtttgaatcctcgggg
atccacgtggcaggactggtggtaggagagtgctgccccacacccagccactggagtgcc
acctgtaccctgcatgagtggctgcaacagcgtggcatacctggcctacaaggagtggac
actcgggagctgactaagaagttgcgagagcaagggtctctgctgggaaagctggtccag
gatgggacggagccttcaaccctgcccttcttggaccccaatgcccgcgccctggtgcca
gaggtctccattaaggtcccacgggtattcaattcagggggtacccctcggatccttgct
ttggactgtggcctcaagtataatcagatccgatgcttgtgccagcgtggggcagaggtc
actgtggtaccctgggaccacgcattagaaagtcaggagtatgagggtctctttctgagt
aatggccctggcgacccggcctcctatcccagcgtggtatccacactgagccgtgtctta
tctgaaccgaacccccgacctgtctttgggatctgcctgggacaccagctgttggcctta
gccattggggccaagacttacaagatgagatatgggaaccgaggccataaccagccatgc
ttgctggtgggctctgggcgctgctttctaacatcccagaaccatgggtttgctgtggaa
acagactcactgccagcaagctggcttcctcttttcaccaacgccaatgatcactccaat
gaaggcattgtacatgagagcctacccttcttcagtgtccagtttcacccagagcaccaa
gctggcccttcagatatggaaattctttttgatatttttctggacactgtgaaagaagcc
accaccaggaaccctgggggccagacagttcgagagcggctggctgagcgcctctgtctc
cctgggattcccaccccaggctctgggcttccaccaccacgaaaggttctgattctgggc
tcagggggcctctccattggccaagccggagagtttgactactcaggctctcaggcgatc
aaggccctgaaggaggagaacatccagacgttgctgatcaaccccaacattgccaccgtg
cagacctcccaggggctggctgacaaggtctatttcctcccaataacacctcactacgta
acccaggtgatacgtaatgagcgcccagatggcgtgttactgacttttgggggccaaaca
gctctgaactgtggtgtggagctgaccaaggctggggtgctcgctcggtatggggtccgg
gtcctgggcacacccgtggagaccattgagctgacggaggatcggcgcgccttcgcctcc
aggatggccgagattggagagcacgtggcccccagtgaggcagcgaactctcttgagcag
gcccaggcagctgccgagagactggggtaccccgtgctggtgcgtgcagcctttgccctg
gggggcctgggctctggctttgcctctaacaaagaggagctctctgctctcgtggcccca
gcttttgcccataccagccaagtgctggtagacaagtccctgaaaggatggaaggagatt
gagtacgaggtggtgagagacacctacggcaactgtgtcacggtgtgtaacatggagaac
ctagatccactgggcatccacactggggagtccatagtggtggctccaagccagacgctg
aatgacagggagtaccagctactgcggcagacggccatcaaggtgactcagcaccttgga
atcgttggggagtgcaacgtgcagtatgccttgaatcctgagtctgagcagtattacatc
attgaagtgaatgccaggctctctcgcagctccgccctggccagtaaggccacgggctat
ccactggcctacgtggcagccaagctggctttgggcatccctctacctgaactcaggaac
tcggtgacagggggaacagcagcctttgaacccagtctggattattgtgtggtgaagatt
cctcgctgggacctcagcaagttcctccgcgtcagcacaaagattgggagctgcatgaag
agtgtcggtgaggtcatgggcattgggcgttcttttgaggaagctttccagaaggctctg
cgcatggtggatgagaactgcgtgggctttgatcacacagtcaagcccgtcagtgacatg
gagttggagactccaacagacaagcgcatctttgtggtggcagctgccctgtgggctggc
tactcggtggatcgcctgtatgaacttactcgcatcgaccgctggtttttgcaccgaatg
aaggggatcgtagcacacacccagctgctggagcaacaccgtggacagtctttgccccta
cccctgctgcagcaggccaagcgcctcggcttctcagacaagcagattgccctcgcagtt
ctcagcacggagctggctgttcgcaagctgcgtcaggaactggggatctgcccagcggtg
aagcagatcgacacagttgcagctgaatggccagcccagacaaattacttgtacctgaca
tactggggcaccacccatgacctcagctttcgaacgcctcatgtcctggtcctgggctct
ggcgtctaccgtatcggctccagcgtcgagtttgactggtgtgctgtgggctgcatccag
cagctccgaaagatggggtataaaaccatcatggtgaactacaacccagaaacagtcagc
accgactatgacatgtgtgaccgactctacttcgatgagatctcttttgaggtggtgatg
gacatctacgagctggagaaccccgaaggcgtgatcctgtccatgggcgggcagctgccc
aacaacatggccatggctttgcatcggcagcagtgccgggtgctgggcacctgccctgaa
gccatcgactcggctgagaaccgttttaagttctcccggctcctggacaccattggtatc
agccagcctcagtggagggagctcagtgacctggagtccgcccgccagttctgccagact
gtggggtatccctgtgtcgtgcgcccctcctatgtgctaagtggtgctgctatgaacgtg
gcttacaccgatggggacctggagcgcttcctgagcagtgcggcagctgtctccaaggag
caccccgtggtcatctccaagttcatccaggaggccaaggagattgatgtggacgctgtg
gcctgtgatggtgtggtggcagccatcgccatctccgagcacgtggagaacgcaggtgtg
cattcaggtgatgccacgctggtgaccccgccgcaggacatcactgccaaaaccctggag
cggatcaaagccatcgtgcacgccgtgggccaggagctgcaggtcacaggacccttcaat
ctgcagctcattgccaaggacgaccagctgaaagtcattgaatgcaacgtgcgtgtctct
cgctccttccccttcgtctccaagaccctgggtgtggacctagtagccttggccacgcgg
gtcatcatgggggaagaagtggagcctgtggggctcatgactggctctggagtcgtgggg
gtaaaggtgccccagttctcattctcccgcctggcgggtgctgatgtggtgctgggtgtg
gagatgaccagtactggggaagtggctggcttcggggagagccgctgtgaggcctacctc
aaggccatgctaagcactggctttaagatccccaagaagaacatcttgctgaccattggc
agctataagaacaaaagtgagctgctcccaactgtgcgactgctggagagcctgggctac
agcctctacgccagtctgggcactgctgacttctatacagagcacggtgtcaaggtaacg
gctgtggactggcactttgaagaagcagtggatggagagtgtccaccacagcgaagtatc
ctggagcagctcgctgagaagaacttcgagctagtgattaacctgtccatgcgcggggct
gggggccggcgtctctcttcctttgtcaccaagggctaccgcacccggcgcctggccgct
gacttctccgtgcccctcatcatcgatatcaagtgcaccaaactgtttgtggaggcccta
ggacagattgggccagcccctcctttgaaggtgcatgtcgactgcatgacctcccagaag
ctcgtgcggctacctggattgattgatgtccacgtgcacctgcgggaaccaggggggaca
cacaaggaggactttgcttcaggcacagcggctgccctggccgggggcatcaccatggtg
tgtgccatgcctaatacctggccccccatcatcgatgcccctgctctggccctggcacag
aagctggcagaggctggcgcccgctgtgactacaccttattcctcggagcttcgtcggaa
aacgcagggaccctgggtgctgtggctgggtctgctgcagggctgaagctctacctcaac
gagaccttctctgagctgcggctggacagtgtggcccagtggatggagcacttcgagacg
tggccgtcccacctccccattgtggcccacgcagagcgtcagagtgtcgccgccgtcctc
atggtggcccagctgacccagcgctcggtacacatctgtcacgtggcgcggaaggaagag
atcctgctgattaaagccgctaaggcacgggggctgccggtgacctgtgaggtggcgccc
caccatctgttcctgagccgcgatgacctggagcgtctggggcccgggaagggggaggtt
cggcctgagcttggctcccggcaggatgtggaagccctatgggagaacatggccgtcatc
gactgctttgcctccgaccatgccccccacaccgtggacgagaagtgtgggccccagcca
ccccccggcttcccggggctggagaccatgctgcccctactgctgacggcagtgagcgag
ggccggctcagcctggatgacctgctgcagcgactgcaccacaaccctcggcgcatcttc
cacctgccgccccaggaggacacctatgtggaggtggatctggagcatgaatggacggtc
cccaaccacatgcccttctccaaggcccactggacacccttcgaagggcagaaggtgaag
ggcaccgtccgccgtgtggtcctgcgaggagaggttgcctatattgacgggcaggtgctg
gtgccgccgggctacggacaggatgtacgcaagtggccacagggggctgttccccagctc
acgccctcggcccccgccgccagtgagctaaacacgaccccagagaggccccgccggggc
atcccagcacttcccgatggccgcttccacctgccgccccgaatccaccgagcctctgac
ccaggtttgccagctgaggagccaaaggagaagacctcccggaaggcagctgagccagag
ctgatgggaacccttgatggcacctgctaccctccaccaccagtacctagacaggcgtcg
ccccagaacctggggacccctggcctgctgcacccccagacctcacccctgctgcactca
ttagtgggccaacatatcctgtctgtccagcagttcaccaaggatcagatgtctcacctg
ttcaacgtggcacacacgctgcgcatgatggtgcagaaggagcggagcctcgacatcctc
aaggggaaggtgatggcctccatgttctacgaggtgagcacgcggaccagcagctccttt
gcagcggccatggcccggctggggggcgccgtgctcagcttctcagaagccacgtcctcc
gtccagaagggtgaatccctggctgactcggtgcagaccatgagctgctacgccgacgtc
gtggtgctgcggcacccccagcccggagcggtggagctggcagccaagcactgccggagg
ccagtgatcaatgccggggatggggtcggagagcatcccacccaggccttgctggacatc
ttcaccatccgggaggagcttgggacggtcaacggcatgacgatcacaatggttggggac
ctgaagcacggacgcacggtgcattcactggcctgcctgctcacccagtatcgcgtcagc
ctgcgctacgtggcgcctcccagcctgcgcatgccccccgacgtgcgggctttcgtggcg
tcccgcggcactaagcaggaggaatttgagagcattgaggaggcgctgcccgacaccgac
gtgctctacatgactcgcatccagaaggagcgcttcggttctagccaggagtatgaagct
tgctttggccagttcatcctcactccccacatcatgacccgggccaagaagaagatggtg
gtgatgcacccaatgccccgagtcaatgagataagtgtggaggtggactcggacccccga
gcagcctacttccggcaggcggagaatggcatgtacatccgcatggctctgttagccact
gtgctcggccgcttctag

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