| Entry |
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| Symbol |
IL6R
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| Name |
(RefSeq) interleukin-6 receptor subunit alpha isoform X1
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| KO |
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| Organism |
pps Pan paniscus (bonobo)
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| Pathway |
| pps01521 | EGFR tyrosine kinase inhibitor resistance |
| pps04060 | Cytokine-cytokine receptor interaction |
| pps04061 | Viral protein interaction with cytokine and cytokine receptor |
| pps04932 | Non-alcoholic fatty liver disease |
| pps05163 | Human cytomegalovirus infection |
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| Brite |
KEGG Orthology (KO) [BR:pps00001]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
100972031 (IL6R)
04066 HIF-1 signaling pathway
100972031 (IL6R)
04151 PI3K-Akt signaling pathway
100972031 (IL6R)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
100972031 (IL6R)
04061 Viral protein interaction with cytokine and cytokine receptor
100972031 (IL6R)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
100972031 (IL6R)
04659 Th17 cell differentiation
100972031 (IL6R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
100972031 (IL6R)
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
100972031 (IL6R)
05163 Human cytomegalovirus infection
100972031 (IL6R)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
100972031 (IL6R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
100972031 (IL6R)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04050 Cytokine receptors [BR:pps04050]
100972031 (IL6R)
04090 CD molecules [BR:pps04090]
100972031 (IL6R)
Cytokine receptors [BR:pps04050]
Interleukin receptor families
IL6/12 receptor family
100972031 (IL6R)
CD molecules [BR:pps04090]
Proteins
100972031 (IL6R)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
1:complement(95364609..95427592)
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| AA seq |
468 aa
MLAVGCALLAALLAAPGAALAPRRCPAQEVARGVLTSLPGDSVTLTCPGVEPEDNATVHW
VLRKPAAGSHPSRWAGMGRRLLLRSVQLHDSGNYSCYRAGRPAGTVHLLVDVPPEEPQLS
CFRKSPLSNVVCEWGPRSTPSQTTKAVLLVRKFQNSPAEDFQEPCQYSQESQKFSCQLAV
PEGDSSFYIVSMCVASSVGSKFSKTQTFQGCGILQPDPPANITVTAVARNPRWLSVTWQD
PHSWNSSFYRLRFELRYRAERSKTFTTWMVKDLQHHCVIHDAWSGLRHVVQLRAQEEFGQ
GEWSEWSPEAMGTPWTESRSPPAENEVSTPTQALTTNKDDDNILFRDSANATSLPVQDSS
SVPLPTFLVAGGSLAFGTLLCIAIVLRFKKTWKLRALKEGKTSMHPPYSLGQLVPERPRP
TPVLVPLISPPVSPSSLGSDNTSSHNRPDARDPRSPYDISNTDYFFPR |
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| NT seq |
1407 nt +upstreamnt +downstreamnt
atgctggccgtcggctgcgcgctgctggctgctctgctggccgcgccgggagcggcgctg
gccccaaggcgctgccctgcgcaggaggtggcgagaggtgtgctgaccagtctgccagga
gacagcgtgactctgacctgcccgggggtagagccggaagacaatgccactgttcactgg
gtgctcaggaagccggctgcaggctcccaccccagcagatgggctggcatgggaaggagg
ctgctgttgaggtcggtgcagctccacgactctggaaactattcatgctaccgggccggc
cgcccagctgggactgtgcacttgctggtggatgttccccccgaggagccccagctctcc
tgcttccggaagagccccctcagcaacgttgtttgtgagtggggtcctcggagcacccca
tcccagacgaccaaggctgtgctcttggtgaggaagtttcagaacagtccggccgaagac
ttccaggagccgtgccagtattcccaggagtcccagaagttctcctgccagttggcagtc
ccggagggagacagctctttctacatagtgtccatgtgcgtcgccagtagtgtcgggagc
aagttcagcaaaactcaaacctttcagggttgtggaatcttgcagcctgatccgcctgcc
aacatcacagtcactgctgtggccagaaacccccgctggctcagtgtcacctggcaagac
ccccactcctggaactcatctttctacagactacggtttgagctcagatatcgggctgaa
cggtcaaagacattcacaacatggatggtcaaggacctccagcatcactgtgtcatccac
gacgcctggagcggcctgaggcacgtggtgcagcttcgtgcccaggaggagttcgggcaa
ggcgagtggagcgagtggagcccggaggccatgggcacgccttggacagaatccaggagt
cctccagctgagaacgaggtgtccacccccacgcaggcacttactactaataaagacgat
gataatattctcttcagagattctgcaaatgcgacaagcctcccagtgcaagattcttct
tcagtaccactgcccacattcctggttgctggagggagcctggccttcggaacgctcctc
tgcattgccattgttctgaggttcaagaagacgtggaagctgcgggctctgaaggaaggc
aagacaagcatgcatccgccgtactctttggggcagctggtcccggagaggcctcgaccc
accccagtgcttgttcctctcatctccccaccggtgtcccccagcagcctggggtctgac
aatacctcgagccacaaccgaccagatgccagggacccacggagcccttatgacatcagc
aatacagactacttcttccccagatag |
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