| Entry |
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| Symbol |
MAP3K10
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| Name |
(RefSeq) mitogen-activated protein kinase kinase kinase 10 isoform X1
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| KO |
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| Organism |
pps Pan paniscus (bonobo)
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| Pathway |
| pps05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:pps00001]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
100977883 (MAP3K10)
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
100977883 (MAP3K10)
05022 Pathways of neurodegeneration - multiple diseases
100977883 (MAP3K10)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:pps01001]
100977883 (MAP3K10)
Enzymes [BR:pps01000]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
100977883 (MAP3K10)
Protein kinases [BR:pps01001]
Serine/threonine kinases: TKL group
MLK family
100977883 (MAP3K10)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
20:46451004..46475968
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| AA seq |
962 aa
MEEEEGAVAKEWGTTPAGPVWTAVFDYEAAGDEELTLRRGDRVQVLSQDCAVSGDEGWWT
GQLPSGRVGVFPSNYVAPGAPAAPAGLQLPQEIPFHELQLEEIIGVGGFGKVYRALWRGE
EVAVKAARLDPEKDPAVTAEQVCQEARLFGALQHPNIIALRGACLNPPHLCLVMEYARGG
ALSRVLAGRRVPPHVLVNWAVQVARGMNYLHNDAPVPIIHRDLKSINILILEAIENHNLA
DTVLKITDFGLAREWHKTTKMSAAGTYAWMAPEVIRLSLFSKSSDVWSFGVLLWELLTGE
VPYREIDALAVAYGVAMNKLTLPIPSTCPEPFARLLEGEPGPRDEECWDPDPHGRPDFGS
ILKRLEVIEQSALFQMPLESFHSLQEDWKLEIQHMFDDLRTKEKELRSREEELLRAAQEQ
RFQEEQLRRREQELAEREMDIVERELHLLMCQLSQEKPRVRKRKGNFKRSRLLKLREGGS
HISLPSGFEHKITVQASPTLDKRKGSDGASPPASPSIIPRLRAIRLTPVDCGGSSSGSSS
GGSGTWSRGGPPKKEELVGGKKKGRTWGPSSTLQKERVGGEERLKGLGEGSKQWSSSAPN
LGKSPKHTPIAPGFASLNEMEEFAEAEDGGSSVPPSPYSTPSYLSVPLPAEPSPGARAPW
EPTPSAPPARWGHGARRRCDLALLGCATLLGAVGLGADVAEARAADGEEQRRWLDGLFFP
RAGRFPRGLSPPARPHGRREDVGPGLGLAPSATLVSLSSVSDCNSTRSLLRSDSDEAAPA
APSPPPSPPAPTPTPSPSTNPLVDLELESFKKDPRQSLTPTHVTAACAVSRGHRRTPSDG
ALGQRGPPEPAGHGPGPRDLLDFPRLPDPQALFPARRRPPEFPGRPTTLTFAPRPRPAAS
RPRLDPWKLVSFGRTLTISPPSRPDTPESPGPPSMQPTLLDMDMEGQNQDSTVPLCGAHG
SH |
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| NT seq |
2889 nt +upstreamnt +downstreamnt
atggaggaggaggagggggcggtggccaaggagtggggcacgacccccgcggggcccgtc
tggaccgcggtgttcgactacgaggcggcgggcgacgaggagctgaccctgcggaggggc
gatcgcgtccaggtgctttcccaagactgtgcggtgtccggcgacgagggctggtggacc
gggcagctccccagcggccgcgtgggcgtcttccccagcaactacgtggcccccggcgcc
cccgctgcacccgcgggcctccagctgccccaggagatccccttccacgagctgcagcta
gaggagatcatcggtgtggggggctttggcaaggtctatcgggccctgtggcgtggcgag
gaggtggcagtcaaggccgcccggctggaccctgagaaggacccggcagtgacagcggag
caggtgtgccaggaagcccggctctttggagccctgcagcaccccaacataattgccctt
aggggcgcctgcctcaaccccccacacctctgcctagtgatggagtatgcccggggtggc
gcactgagcagggtgctggcaggtcgccgggtgccacctcacgtgctggtcaactgggct
gtgcaggtggcccggggcatgaactacctacacaatgatgcccctgtgcccatcatccac
cgcgacctcaagtccatcaacatcctgatcctggaggccatcgagaaccacaacctcgca
gacacggtgctcaagatcacggactttggcctcgcccgcgagtggcacaagaccaccaag
atgagcgctgcggggacctacgcctggatggcgccggaggttatccgtctctccctcttc
tccaaaagcagtgatgtctggagcttcggggtgctgctgtgggagctgctgacgggggag
gtcccctaccgtgagatcgacgccttggccgtggcgtatggcgtggctatgaataagctg
acgctgcccattccctccacgtgccccgagccctttgcccgcctcctggagggtgagccg
gggccccgtgacgaggaatgctgggacccagacccccatgggcggccagatttcggtagc
atcttgaagcggcttgaagtcatcgaacagtcagccctgttccagatgccactggagtcc
ttccactcactgcaggaagactggaagctggagattcagcacatgtttgatgaccttcgg
accaaggagaaggagcttcggagccgtgaggaggagctgctgcgggcggcacaggagcag
cgcttccaggaggagcagctgcggcggcgggagcaggagctggcagaacgcgagatggac
atcgtggaacgggagctgcacctgctcatgtgccagctgagccaggagaagccccgggtc
cgcaagcgcaagggcaacttcaagcgcagccgcctgctcaagctgcgggaaggcggcagc
cacatcagcctgccctctggctttgagcataagatcacagtccaggcctctccaactctg
gataagcggaaaggatccgatggggccagcccccctgcaagccccagcatcatcccccgg
ctgagggccattcgcctgactcccgtggactgtggtggcagcagcagtggcagcagcagt
ggaggaagtgggacatggagccgcggtgggcccccaaagaaggaagaactggtcgggggc
aagaagaagggacgaacgtgggggcccagctccaccctgcagaaggagcgggtgggagga
gaggagaggctgaaggggctgggggaaggaagcaaacagtggtcatcaagtgcccccaac
ctgggcaagtcccccaaacacacacccatcgcccctggcttcgccagcctcaatgagatg
gaggagttcgcggaggcagaggatggaggcagcagcgtgcccccttccccctactcgacc
ccgtcctacctctcagtgccactgcctgccgagccctccccgggggcgcgggcgccgtgg
gagccgacgccgtccgcgccccccgctcggtggggacacggcgcccggcggcgctgcgac
ctggcgctgctaggctgcgccacgctgctgggggctgtgggcctgggcgccgacgtagcc
gaggcgcgcgcggccgacggcgaggagcagcggcgctggctcgacggcctcttctttccc
cgcgccggccgcttcccgcggggcctcagcccacccgcgcgtccccacggccgccgcgaa
gacgtgggccccggcctgggcctggcgccctcggccaccctcgtgtcgctgtcgtccgtg
tccgactgcaactccacgcgttcactgctgcgctctgacagtgacgaggccgcaccggcc
gcgccctccccaccaccctccccgcccgcgcccacacccacgccctcgcccagcaccaac
cccctggtggacctggagctggagagcttcaagaaggacccccgccagtcgctcacgccc
acccacgtcacggctgcatgcgctgtgagccgcgggcaccggcggacgccatcggacggg
gcgctggggcagcgggggccgcccgagcccgcgggccatggccctggccctcgtgacctt
ctggacttcccccgcctgcccgacccccaggccctgttcccagcccgccgccggccccct
gagttcccaggccgccccaccaccctgacctttgccccgagacctcggccggctgccagt
cgcccccgcttggacccctggaaactggtctctttcggccggacactcaccatctcgcct
cccagcaggccagacactccggagagccctgggccccccagcatgcagcccacactgctg
gacatggacatggaggggcagaaccaagacagcacagtgcccctgtgcggggcccacggc
tcccactaa |
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