KEGG   Phodopus roborovskii (desert hamster): 127212934
Entry
127212934         CDS       T08852                                 
Symbol
Mgst1
Name
(RefSeq) microsomal glutathione S-transferase 1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
prob  Phodopus roborovskii (desert hamster)
Pathway
prob00480  Glutathione metabolism
prob00980  Metabolism of xenobiotics by cytochrome P450
prob00982  Drug metabolism - cytochrome P450
prob00983  Drug metabolism - other enzymes
prob01100  Metabolic pathways
prob01524  Platinum drug resistance
prob05200  Pathways in cancer
prob05204  Chemical carcinogenesis - DNA adducts
prob05207  Chemical carcinogenesis - receptor activation
prob05208  Chemical carcinogenesis - reactive oxygen species
prob05225  Hepatocellular carcinoma
prob05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:prob00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    127212934 (Mgst1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    127212934 (Mgst1)
   00982 Drug metabolism - cytochrome P450
    127212934 (Mgst1)
   00983 Drug metabolism - other enzymes
    127212934 (Mgst1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127212934 (Mgst1)
   05204 Chemical carcinogenesis - DNA adducts
    127212934 (Mgst1)
   05207 Chemical carcinogenesis - receptor activation
    127212934 (Mgst1)
   05208 Chemical carcinogenesis - reactive oxygen species
    127212934 (Mgst1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    127212934 (Mgst1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    127212934 (Mgst1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    127212934 (Mgst1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:prob02000]
    127212934 (Mgst1)
Enzymes [BR:prob01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     127212934 (Mgst1)
Transporters [BR:prob02000]
 Other transporters
  Pores ion channels [TC:1]
   127212934 (Mgst1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 127212934
NCBI-ProteinID: XP_051029094
UniProt: A0AAV0ABB9
LinkDB
Position
Unknown
AA seq 155 aa
MSELKQLMDNEVLMAFASYATIVLTKMMFMSSATAFQRLTNKIFANPEDCASFCKGENAK
KFVRTDEKVERVRRAHLNDIENIVPFLGIGLLYSLSGPDLSTALMHFRIFVGARIYHTIA
YLTPLPQPNRALAFFAGYGVTLSMAYRLLKSRLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atgtctgaactcaagcagctcatggacaatgaggtgttgatggcttttgcctcttatgca
actatcgttcttaccaagatgatgttcatgagctctgcgactgcattccagaggctaacc
aacaagatttttgccaacccagaagactgtgctagcttttgcaagggagagaatgccaag
aagtttgtccggactgacgaaaaggttgaacgggtgcggagagcccacctgaatgatatt
gaaaacatcgttccttttcttggtatcggcctcctctactccctgagtggtccagacctc
tcaactgccctcatgcacttcagaatctttgttggtgctcggatctaccacacaatcgcc
tacttgactcctcttcctcagcctaatagggccttggcattttttgctggctatggagtt
actttgtcaatggcttacaggctgctcaagagtagattgtacctgtga

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