Polyodon spathula (Mississippi paddlefish): 121323429
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Entry
121323429 CDS
T07273
Name
(RefSeq) protein unc-80 homolog isoform X1
KO
K24015
protein unc-80
Organism
pspa
Polyodon spathula (Mississippi paddlefish)
Brite
KEGG Orthology (KO) [BR:
pspa00001
]
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pspa04040
]
121323429
Ion channels [BR:
pspa04040
]
Voltage-gated cation channels
Sodium leak channel, non-selective
121323429
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UNC80_C
UNC80
UNC80_N
GRP
Motif
Other DBs
NCBI-GeneID:
121323429
NCBI-ProteinID:
XP_041120446
LinkDB
All DBs
Position
11:3050450..3116772
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AA seq
3316 aa
AA seq
DB search
MVKRKSLEDPDQECGRGIPFPIQTFLWRQTSAFLRPKLGKQYEASCVSFERVLVENKLHG
LSPALSEAIQSISRWELVQAALPHVLHCTAILLSNRNKLGHQDKLGVAETKLLHTLHWML
LDAAQECNHEAGVRGGRGSSWSGSSSAFIHQMENQGSPGQPPHGSTPEDDEHSKQKLFHK
SMATVELFVFLFAPLIHRIKESDLTFRLSSGLVIWQPMWEQKQPDVPAFTALIKPVRNIV
TAKRNSPTNNQRSACESPNPGSTGFQVVCETAQSDSLSSGASVQSCRRGNSLEGGGPSQA
SKDKGLSQNKASTAAPPAQRSRYGTYFDVAVLRCLLQPHWSEEGTHWALLYCLQRLRQIL
EEKPERPPEPLLTQLPRPRSSSMVAAAPSLVNTHKTQDMTSKCNEEEKSLSTETFSKVSL
TNLRRQAVPDLSSDLGMNIFKKFKSRKEERERKGSIPFHHTGKRRQRRMGVPFLLHEDHL
DVSPTRSTFSFGSFSGIGDERRGLEKGGWQTAILGKFTRRGSSDTTADVDSLSARQSHSH
HTLMSDAHDQPNSHGENTVKEVRSQISTITVATFNTTVASFNVGYADIFTEHMKKLCNPV
PIPEMPIEPLACSNLPRSLTDSCINYSCLEDAESIEGTNNFILKNGMLDLTVILRAVYVV
LTHDISSRICDVTLNIIECLLQLGVVPSMGKKVSKVEEKENEETRLKDGTNQRTGGANVG
VAGGMGAAPGGGGGGGNGGGGGGGGGDDGKNNRQQGNKEDSVPQSSHRLALTMLIKIVKS
LGCAYGCGEGHRGLSGDRLRMQAQNCLTLLYKLDKLQFRQTMRDYVNKDSLNNVVDFLHA
FLGFCMEPITDKYGSAGERSRREKKRNLDKAGFGNNFTTGDSKSVAQNMETVVVGCMFKS
LITRCASTTHELHSPENLGLYCDIRQLVQFIKESHGNVFRRVALSALLDSAEKVTSGKKT
EEKDETKLPGNRRSDAGNTNDKGQPSSAADECRSYISSRLPQTPEHDEQIPGALLGRKDF
WRKMFKSQSAASDTSSQSEQDTSECTTAHSGTTTERRSRSRSRSRRISLRKKLKLPIGNW
LKRSSLSGLTDGVEDLLDISSVDRLSFIRQSSKVKFTSAVKLSEGGAMEYGRDEEENFFK
RLGKWRSGRRNPSKLHHTEEKDDIILRRPACPSLSGCRGFEERLAGSQEGMKNKNMVNLG
AIRQGMKRFQFLLNCCEPGTIPDASILAAALDLEAPVVARASLFLECARFVHRCNRGNWP
EWMKGHHVNIIKRGLSRGRSPVVGSKRNQKLQWNAAKHFCQWGDAIGARLSELCHLESES
PANILGFIYDEETKRRMRKEDEEEDFLDDNTVNPTKCACPFALKMAACQLLLEITTFLRE
TFPCLPRPRTEPLVDLESCRLRLDPELDRHRYERKISFAGIIDDEEGHDSLHSSSHTLKS
DSACEEKRAPIRKIRIGGSRLLQIKGARSFRVKKGGSLSSIRRAGSLKSTKMSRQDSESE
NEEVLLSQSRDTVTDIGSPWSTSEPSIEPEGLSSTGNEENYHRNMSWLHIMILLCNQQSF
ICTHVDFCHPCCYQHHSRSCARLVRAVKLLYGDTVDGLKEDSLTSNIGFRAKKTKECSDK
SCLRTPSLKRRTTDATPEGKKDTGMLKYIRNQVMSLSPAPLSLLIKAAPILTDEMFGDVQ
PAAWELLLSVDEHMAAAAAALFLLCAVKVSDAVSDMMMSEFHHQEAVQRINSVLRFYTLW
RFRFRVWPRMEEGAQQIFKIPPPSINFTLPSPILGMPCVPMFDPPWVPQSTGSVQDPINE
DQSKSFSARAVSRSHQRAEHILKNLQQEEEKRRLGREASIITSTPITQEACYEPTCSPPS
EQEEEAEEVTNLVSRRLSISPSCTSSTSHRNYSFRRGSVWSMRSAVSAEDEENVTEHTPT
HHVPQPPQVVFPACICAAVLPIVHLMEDGEVREDGVAVSAVAQQVLWNCLIEDPALVLRH
FLEKLTVSNRQDELIYMLRKLLLNIGDLPAQTSHILFNYLVGLIMYFVRTPCEWGMDAIS
ATLTFLWEVVGYVEGLFFKDLKQTMKKEQCEVKLLVTASMPGTKTLVVHGQNECDIPTQL
PVHEDTQFEALLKECLEFFNIPEAQSARYFLMDKRWNLIHYSKTYVRDIYPFRRSVSPQL
NLVHMLPDKGQELIQKQVFSRKLEEVGRVLFLISLTQNMPAVHKQSHVSLLQEDLLRLPS
FPRNAVDAEFSLFSDPQGKELFGLDTLHKVLWIKLLEEMFLGMPSEYPWGDEIMLFLNVF
NGVLILHPEDSALLRQYTATVINTAVHFNHLFSLSGYQWILPTMLQAYADYESNPLLRQA
IEFSCRQFYILHRKPFVLQLFASVAPLLEFTTCTSSRQSKGVSAQCLFDLLVSLEGDAPD
TLDSLELVKAEKPLRSLDFCYGNEDLNFSISKAIKLCVTVVAYAPESFRSLHMLMVLEAL
VPCFLQELKKETIALETASAARDEIAAIATLATSLQALLYSVEALTRPMTAPQMSRSEQG
HKGAATANHTVPGGADTRDNLHLLEEGQGLPREELDERIAREEFRQPRESLLNICTEFYK
HCGPRLKILQNMTGEPRVTTLELLDIKSHMRLAEIAHSLLKLAPYDTLTMESRGLRRYIM
EMLPITDWTTEAVRPALILILKRLDRMFNKIHKMPTLRRQVEWEAASSLIEGICLTLQRQ
PIISFLPHLRSLINVCVNLVMGVVGPSSVADGLPLLHLSPYLSPPLPFSTAVVRLVALQI
QALKDDFPLSHVISPFTNQERREGMLLNLLIPFVLTVGSGSKDSPHLEQPEVFLLLQTVI
NILLPPRIISTSRSKNFMMESSPAHCSTPGDTGKDLRREGLAESTSQAAYLALKVVLVCF
ERQLGNQWYQLSLQVKEMALRKVGGLALWDFIDFIVRTRIPIFILLRPFIQCKLLTQPAE
SQEEITARHHIADQLERRFIPRPLCKSSLIAEFNNELKILKEAVHSGAGEKTYQGKTSIS
TVGTSTSAYRLSLATMSRSNTGTGTVWQDTLSRTDEDDEENDSVSMPSVVSEHEAYLASV
IGRRRFSSHVSSASAPTAEPVLSTMLPSQSEPNVLDESQGMNAEGNLSRVASVQSEPGQQ
NLLVQPALGRKRGLRQPRRPLLLMQKTQNEPHSRPRARLSTTRRSIQPKSRTLEQKRLVT
FPKAQPEAAALSPPAESKECPSENQNLGVTSSSAASPSIVTADLHSPTAAKVETTGLETK
NKAEPRSCLSPPPPPVLGTLPHPASLPPESPRETSSLLPHTDTVLHISEDNDTESSLLSP
AFTYTYVELGKDESHV
NT seq
9951 nt
NT seq
+upstream
nt +downstream
nt
atggtgaagaggaagagtttagaggatcccgatcaggaatgcgggagaggtatacctttc
ccaatccagacgtttctgtggagacaaaccagtgcatttttgagaccaaaacttgggaag
cagtatgaagcgtcctgtgtgtcgttcgagagagtgctggtggagaacaagctgcatggc
ctgtctcccgctctctcggaggcaatccagagcatctcgcgttgggagctggtgcaggcg
gcccttccccatgtgctgcactgcactgccatcctgctctccaaccggaacaagctgggt
caccaggacaagctgggtgttgcagagacaaagcttctgcacaccctgcactggatgctg
ctggatgctgcccaggagtgtaaccacgaggctggggtgagagggggtcgggggtccagc
tggtcagggagcagcagtgccttcattcaccagatggagaaccagggctcccccggccag
cccccgcatggcagcacccccgaggatgacgagcacagcaagcagaagcttttccacaag
tccatggccaccgtggagctctttgtgttcctctttgctcctctcatccacaggatcaag
gagtcagatctgacattccgattgtccagtggccttgtcatctggcagccaatgtgggag
cagaaacagcccgatgtccctgccttcactgctctcatcaagccagtcagaaacattgtt
acagcaaagagaaactccccaaccaacaaccagaggagtgcgtgtgaatcccccaaccca
ggctccacgggtttccaggtggtttgtgagactgcccaatcagattcactgtcatcaggg
gcaagtgtgcagagctgtcgccgtggcaactctcttgaaggaggcgggccttcccaggcc
tccaaggacaagggactctcccagaacaaagcttcgaccgcagccccccctgcgcagagg
tctcgctacggcacctatttcgacgtggcggtgctgcgctgtctcctgcagccccactgg
tccgaagaggggacccactgggcgctgctgtactgcctgcagaggctgcgtcagatcctg
gaggagaagcctgagagacccccggagcccctcctcacacagctgcccagaccacgcagc
agctccatggtggcagccgcaccctccctggtgaacacacacaagacacaggacatgact
tcaaaatgcaatgaggaggagaagtccctcagcacagaaaccttctccaaggtgtccttg
acgaacctgagaaggcaggctgtcccggacctgtcctctgacctgggcatgaacatcttc
aaaaagtttaagagccgcaaggaggaacgtgagcgaaagggctcaatcccgttccaccac
accgggaagaggcgtcagcggcgcatgggggtccccttcctgctgcacgaggatcacctg
gacgtgtctcccacgcgcagcaccttttccttcgggagcttctccgggattggtgacgag
cggcgcgggctcgagaaggggggttggcagactgccatcctggggaagttcacacgcaga
ggcagctccgataccaccgcagatgtggacagcctcagcgccagacagtcccactcgcac
cacacactgatgagcgatgcccacgaccaacccaacagccacggtgaaaacaccgtcaag
gaagtcaggtcccagatatccaccatcactgtggcaaccttcaacaccacggtggcctcg
ttcaacgtgggctacgcagacatctttacagagcacatgaagaagctgtgcaacccggtg
cccatcccagagatgcccatcgagcctctggcctgctccaacctgccacgcagcctcact
gactcctgcatcaactacagctgcctggaggatgcagagagcatcgaggggaccaacaac
ttcatccttaagaacggcatgctggacctcacggtgatcctgagagctgtgtacgtggtc
ctgacccacgacatcagctcacgaatctgcgacgtgactctgaacatcatcgagtgcctc
ctgcagctgggagtggtacccagcatggggaagaaggtgtccaaggtggaagagaaggag
aatgaggagaccaggctcaaggatgggaccaatcagaggacagggggagccaacgtgggt
gtggctggaggaatgggggcggcgccgggaggaggaggagggggcgggaacggaggagga
ggaggaggaggaggaggagatgatggcaagaacaacaggcagcaaggaaacaaggaagat
agtgtgccccagagcagccacaggttggccctcacaatgctgattaaaatcgtcaagtct
ctcggctgtgcctatggatgtggagagggacacagaggcctctctggagatcgcttacgg
atgcaggctcagaactgcctgaccctcctgtacaagctggacaagctccagttccgtcag
acaatgagagactatgtgaacaaggactcgctcaacaacgtggtggacttcttacacgcc
tttctgggcttctgcatggaacctatcaccgacaaatacggaagtgcaggtgagaggtcc
aggagagagaaaaaaagaaacctcgacaaggcgggtttcgggaacaatttcactacaggg
gacagcaaatcggttgctcagaacatggagacggtggtcgtgggctgcatgttcaagtct
ctgatcacacgttgtgcatccaccacacatgagcttcacagcccggagaacctgggtctg
tactgtgatatccggcagctggtgcagttcatcaaggagtcccacgggaatgtcttccgc
agagtggctctcagtgccctcctggacagtgcagagaaagtcacttctgggaaaaagaca
gaggagaaggacgagacgaaacttccagggaaccgaaggtctgatgcggggaacacaaac
gacaagggacagccctcgtctgccgcggatgagtgtcgtagttacatctccagtcgtctc
ccacagaccccagagcatgatgagcagatcccgggggctctcctcgggcgaaaggacttc
tggcgcaaaatgttcaagtcccagagtgcagcgagtgacacaagcagccagtcagagcag
gacacttcagagtgcacaaccgcccactcgggaaccaccaccgaacgacggtcccgctcc
cgctcccgatcccgacgcatctccctccgcaagaaactcaaactgcccataggaaactgg
ctgaaacgctcctccctctcgggtctgacagatggggtagaggacctgctggacatcagc
tctgtggacaggctctccttcatacgccagagttccaaggtgaagttcaccagcgcagtg
aagctgtctgaaggaggcgctatggagtacggccgggacgaagaggagaatttcttcaag
cggcttggtaaatggcgctccggccgaaggaacccatccaagcttcaccacacagaagaa
aaagatgacatcatattgcgccgtcctgcctgcccgtctctctcagggtgccgtggcttc
gaggagcgcctagccggcagccaggaggggatgaagaacaagaacatggtgaatctggga
gccatccggcagggcatgaagcgcttccagttcctgctgaactgctgcgagcctggaacc
atccctgacgcatccatcctggcggccgccctcgacctggaggccccagtggtggcgaga
gcatctctcttcctggagtgcgcccgttttgtgcaccgctgtaaccgtggaaactggccg
gagtggatgaaggggcaccacgtgaacatcatcaagcgtggcctctcccggggccgctcc
ccagttgtcggcagcaagaggaaccagaagctccagtggaacgctgccaagcacttctgc
cagtggggagatgctatcggtgcccgactgagcgagctgtgccacttggagagcgagagt
cccgctaatatcctgggcttcatttatgacgaggagacgaagcgacggatgaggaaggag
gatgaggaggaggatttccttgatgacaatactgtgaacccaacaaaatgtgcctgcccc
tttgccctgaagatggccgcatgccaactcttgctggaaatcaccaccttcctgcgagag
acctttccttgcctgccacgcccccgcacagagcccctggtggacctggagagctgcagg
ctgcgtctcgaccccgagctggaccgtcatcgctacgagaggaagatcagctttgccggg
atcatcgacgacgaagaggggcacgactccctgcacagcagcagccacaccctgaaatca
gactccgcctgtgaggagaagagagctcctatcagaaagatcaggattggtgggtctcgg
ctgctgcagatcaagggagctcgaagttttcgggtgaagaaaggaggctccctgtccagc
atccgccgggccggcagcttgaagagcaccaaaatgtcaaggcaggactcggagtccgag
aacgaggaggtcttgctgtcccagagcagagacactgtcactgatatagggagtccctgg
agcaccagcgagcccagtattgaacccgagggcctgagcagcacagggaatgaggagaac
taccacagaaacatgtcctggctgcacatcatgatcctgctctgtaaccagcagagcttc
atttgcacgcacgtggatttctgccacccgtgctgctaccagcaccacagccgctcgtgc
gcccgcctggtcagagctgtcaagctgctgtatggggacacagtggacgggctcaaggag
gacagccttaccagcaacatcggcttccgggccaagaagaccaaggagtgctcagacaag
tcctgtctcaggacgccttccctaaagagaagaacgactgacgccactccggaagggaag
aaggacactggaatgctgaagtacatccgcaaccaggtgatgagcctctccccggccccc
ctgtctctgttgatcaaggcggctccgatcctgactgatgaaatgttcggggacgtccag
cctgcagcgtgggagctcctgctgagtgtggacgagcacatggcagctgctgcagctgcc
ctgttcctgctgtgtgcagtgaaggtgtcggacgctgtctctgatatgatgatgtctgaa
ttccaccaccaggaggcagtgcagagaatcaactcggtgctcaggttctacacgctgtgg
cgcttcaggtttcgggtgtggccgcgcatggaggaaggggcccagcagatctttaagatc
ccgccccccagtataaacttcacgctgccctccccgatactgggaatgccttgtgtgccc
atgtttgaccccccctgggtgccccagagcactggtagtgtccaggaccccatcaatgag
gaccagtccaaatcattctccgcgcgggcggtgtctcgctctcaccagcgcgcagagcac
atcctgaagaacctgcagcaggaggaggagaagaggcggctgggccgtgaggccagcatc
atcacctccacccccatcacccaggaggcctgctacgagcccacctgcagccccccgtcc
gagcaggaggaggaagcagaagaagtcacaaacctggtgtctcggcggctctcaatcagc
ccctcctgcacctccagcacctcccacaggaactattccttccgcaggggctcagtgtgg
tcaatgcgctccgcggtcagtgctgaagatgaagagaacgtgacggagcacacgcccaca
caccacgtcccacagccgccacaggtggtgttcccagcatgcatctgtgcggccgtgctg
cccattgttcacctcatggaggacggggaggttcgagaggatggagtagcagtgagcgcg
gtggctcagcaggtgctgtggaactgtttgattgaagaccccgccctcgtcctgaggcac
ttcctggagaagctcactgtcagtaatcgccaggacgagctgatttacatgctgaggaag
ctcctgctgaacattggagacctgccggctcagacatcacacatcctctttaactacctg
gtggggctgatcatgtactttgtgcgcactccgtgtgagtgggggatggatgccatctca
gccaccctgaccttcctctgggaggtggtgggctacgtggaggggctgttcttcaaggac
ctcaagcagaccatgaagaaggagcagtgtgaggtgaagctgctcgtcacagcctccatg
ccaggcaccaagactctggtggtacacgggcagaacgagtgtgacatccccacccagctc
cccgtgcatgaggacacgcagttcgaggctctgctcaaggagtgcctggagttcttcaac
attcccgaggctcagtccgctcgttactttctgatggacaagcgctggaacctcatccat
tactccaaaacctatgtgcgagatatatacccattccggcggtcagtctcgccccagctc
aacctggtccacatgttacctgacaagggacaggagctcattcagaagcaggtgttttcc
cggaagctggaggaggtgggccgcgtcctcttccttatctcgctcacccagaacatgcct
gctgttcacaagcaatcccacgtgtccctgctccaggaggacctgctcagactcccatca
ttccccaggaacgccgtggacgccgagttctctctcttcagtgatccccaagggaaggag
ctctttggcctggacaccctgcacaaagtcctgtggatcaagctgctggaggagatgttc
ctgggcatgcccagtgagtacccctggggagacgagatcatgctcttcctgaatgtgttc
aacggagtcctgatcctgcacccggaggacagcgccctcctgaggcagtacactgccacg
gtcatcaacaccgccgtccacttcaaccatctcttctcactcagcggctaccagtggatc
ctgcccaccatgctgcaggcctatgcagactatgaaagcaatccattactgcggcaggct
atagagttttcctgcaggcagttctatatcctccaccggaagcctttcgttctgcagctg
tttgccagcgtggcaccactgctggagttcacgacctgcacaagcagcaggcagtccaaa
ggagtgtcagctcagtgcctgtttgacctgctggtgtctctagaaggggacgccccggac
accctggactccctggagctagtgaaggcagagaagcccctccgctctttagacttctgc
tacgggaacgaggacctcaacttttctatcagtaaagccatcaagctgtgcgtgacagtg
gtggcttatgcacccgagtccttcagaagcctgcatatgctgatggtgctggaggccctg
gtcccctgtttcctgcaggagctgaagaaggagaccatagctctggagacggcctccgca
gccagggacgagatcgcagctatcgccacccttgccacctccctccaggctctgctgtac
agcgtagaggctctcaccaggcccatgactgcaccacagatgagtcgcagtgaacaagga
cacaaaggagcggccactgccaatcacaccgtgccagggggcgctgacaccagggataac
ctgcacctgctggaggagggccaggggctccccagggaggagctggatgagcgcatcgcc
cgagaggagttcagacagccccgggagtctctgctcaacatctgcaccgagttctacaag
cactgcggcccccggctcaagatcctgcagaacatgactggggagccacgcgtcaccaca
ctggagctgctcgacatcaagtcacacatgaggctggctgagatcgcacactccctgctg
aagctggctccctatgacaccctgaccatggagagccgtggtctgagacgctacatcatg
gagatgttgcccatcaccgactggaccactgaggccgtgcggcccgccctcatcctcatc
ctcaagaggcttgaccgcatgttcaacaagatccacaagatgcccactctgagacggcag
gtggagtgggaagctgccagcagcctgattgaaggaatttgcctgacccttcagcgacag
cccatcatatccttcctcccgcacctccggtcgctgatcaacgtctgcgtcaatctggtg
atgggtgtggttggaccctccagcgtggctgatggcttgcctcttcttcacctgagtccc
tacctctcccctccgctccccttcagcactgccgtggtcagactcgtggctctgcaaata
caggcgctaaaagatgacttcccccttagccacgtgatctccccattcaccaatcaggag
agacgagaaggaatgcttcttaacctgctgattccgtttgtgctgacggtgggatctggc
agtaaagacagccctcacctagagcagccagaggtgttcctgctgctgcagaccgtcatc
aacatcctgctgccgccgcgcatcattagcacctcgcgcagcaagaacttcatgatggag
agctctccggcgcactgctccacaccgggagacacgggcaaggacctgcgccgggaaggg
ctggccgagtccaccagccaggccgcctacctggctctgaaggtggtcctggtctgtttt
gagcggcagctggggaaccagtggtaccagttgagtctgcaggtgaaggagatggcgctc
cgcaaggtgggcgggctggccctgtgggacttcatcgacttcattgtgagaaccaggatc
cccatcttcatactgctccgccccttcatccagtgcaagctcctgacccagcctgcggag
agccaggaggagatcacggcccggcaccacatcgctgaccagctggagcgacggttcatc
ccccgtccgctctgcaagagctccctcatcgccgagttcaacaatgagctcaagatcctc
aaggaggcggtgcacagtggcgcaggtgagaaaacgtaccagggcaagacctccatcagc
accgtgggcacatccacctctgcctaccgcctgagcctggccaccatgtcacgatccaac
acagggaccgggaccgtctggcaggacactctgagccgcaccgacgaggacgatgaagaa
aatgactctgtgagcatgcccagtgtggtgagtgagcatgaagcctaccttgccagtgtg
atcgggcgccggcggttctccagccacgtgtccagcgcgtcggctccgacggctgagcct
gtgctcagcaccatgctccccagccagagtgaacctaatgtcctagatgaatcccagggg
atgaacgcagagggtaacctgtctagggtggccagtgttcagagtgagccggggcagcag
aacctcctggtccagcctgccctgggcaggaagagagggctacggcagccgaggaggcct
ctgcttttgatgcaaaagacccagaacgagccccacagtcgccccagagctcgcctctcc
accacacgcaggagcatccagcccaaatccaggacccttgaacagaagaggttggttacc
ttccctaaagcacagcctgaggcagcagctttgtcccccccagctgagagcaaagaatgc
ccatcagagaaccagaacctcggagtcacatcatcgtctgctgcctctccttccattgta
actgcagacctgcacagccccacagcagccaaggtggagacaactggcttggagactaag
aacaaagcggagccacggagctgcctgtcccctcccccacctcctgtgctgggcaccctg
ccccaccctgcctccctgcctccagagagccccagagagacctccagcctgctgccgcac
actgacaccgtcctgcacatcagcgaggataacgacacggagagctccctgctctcccca
gccttcacctacacctacgtcgagctggggaaagacgagtcccacgtttaa
DBGET
integrated database retrieval system
