Puntigrus tetrazona (Sumatra barb): 122325080 Help Entry 122325080         CDS       T08985                                  Symbol ryr3 Name (RefSeq) ryanodine receptor 3 isoform X1   KO K04963   ryanodine receptor 3 Organism ptet  Puntigrus tetrazona (Sumatra barb) Pathway ptet04020   Calcium signaling pathway ptet04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:ptet00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     122325080 (ryr3)    04020 Calcium signaling pathway     122325080 (ryr3)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:ptet04040]     122325080 (ryr3) Ion channels [BR:ptet04040]  Voltage-gated cation channels   Ryanodine receptor    122325080 (ryr3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RyR RYDR_ITPR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 Ago_Mid EF-hand_6 EF-hand_8 Motif Other DBs NCBI-GeneID:  122325080 NCBI-ProteinID:  XP_043075889 LinkDB All DBs Position 20:complement(15185712..15252625) Genome browser AA seq 4864 aa AA seqDB search MAEGGEGEDEVQFLRTDDEVVLQCVAAIQKENRKFCLSAEGLGNRLCYLEPTSEAKYFPP DLCICNFVLEQSLSVRALQEMLAGQSGEGNPDHEQWAAQGGGHRTLLYGHAILLRHSFSG MYLTCLKTSRSLTDKLSFDVGLQEDSTGEACWWTIHPASKQRSEGEKVRIGDDLILVSVS SERYLHLSISNGSIQVDASFMQTLWNVQPTCSRSNMEVGFLLGGHVMRLFHGHDESLTIP GSEQSQEQQRVVNYETGKGGSKARSLWRLEPLRISWSGSHIRWGQPFRLRHLSTGHYLGQ TEDNGLILLDREKSDTTATAFCFRSSKEKIDSGPKRDIDGMGVAEIKYGDSVCFIMHVST GLWLSYQAPDAKSSRLGPLKRRAVLSLEGHMDDGLTLQLCQHEESRAARIIRNTTRLFTQ FIRGLDGLNGEKTTEVTLPVCEVLQTLDDLIVYFQQPDSELEHEEKQRQLRSLIKRQDLF KEEGMLTLVSHCIDRLNVYNSAAEFEELAGEEAGEAWKDILNLLYELLAALIRGNRTNCT QFSRKLDWLVSKLERLESSSGILEVLHSILIESPESLNIIQKAHIKSIISLLYKHGRNHK ILDVLCSLCVCNGVAVRANQNFICDHLLPRRDLLLQTRLVNDVQSMRPNIFLGMSEGSAQ YRKWYFELIIDQVDHYVTSEPTHLRVGWATTKGYAPYPGGGEGWGGNGAGDDLYSYSFDG LHLWSGRIPRAVASINQHLLNSDDVVSCCLDLGAPSMSFRINGQPVQGMFEDFNVDGFFF PVVSFSAGVKVRFLLGGRHGDFKFLPPAGYAPCYEALLPKEKMRVEPVKEYKRDLEGVRD LLGTTEFLSQASFIPVPVDTSQIVLPPHLENVRDKLAENIHELWGMNKIELGWMYGKVRD DNKRQHPCLVDFSKLPETEKNYNLQMSTETLKTLLALGCHVAQVNINAEDDLKKMKLPKN YMMANGYKPTPLDLSDVKLTPGQEVLVDKLAENAHNVWAKDRIKQGWTYGIQQDLKNRRN PRLVPYALLDERTKKSNRDSLREAIRTLVGYGYFIDPPDQETAHTVEKEGIESIRLFRVE KTYAVKTGKWYFEFEALTGGDMRVGWARPGCRPDMELGLDDQSFVFDGYRGRRVHMGSHF FGRTWTKGDVVGCMINMEDKSMIFTLNGEIIITNKGSELCFADFEAEDGFIPVCSLGLSQ IGRMNLGKDASTFKYYTMCGLQEGFEPFAVNMNREVTMWFSKRLPTFVNVPEDHPHIEVT RIDGTVDTPPCLKVTHKTYGTQTSNDDMVCCRLSMPVEFHSGPRKITDINEVIAEDQRAK KDDSGKIDYGSITKYFYSVRVIAGQDPSSVWVGWVTPDYHYYSKQFMLSTVRTVTVTLGD ERGRVHESVRRSNCYMVCAGDVVNSSTGRSNTDLEIGCSIDLASGLVSFTANGRDLPTAY QVEPNTKLFPAVFVQPTSPNLFQFEFPKIPDAMPLSSAIFKSLQRNPEPQCPPRLDVQTI VSVLWSRMPNTFLTVETARVSERHGWVLQCLEPLQMMAVHIPEENRCIDIMELSENEDLR QFHYHTLKLFCALCALGNTRVAHALCSHLDQSQLLYTIDNQYLSGQLREGFYNVLISIHL ETGKEAHLMMNNEFIIPVTDETRSIRLFPDDSKCHSLPGVGLSTSLTPRLYFTPPYFITP KRDQPLFSPQIPLGILKEKAISMLTEAVQGGGAHIRDPVGGSVEYQFVPILRLIGTLLIM GAMTSEEVRTILLLVDPIVFGDGKEEEEQVAVVEQGAEKEEAASNEEKAVEAGEEESKEA KQSPKGLLEKSLPESVKRQMCELLHYFCDCELKQRIEAIVAFSDDFVSKLQFNQKFRYNE LMQALNMSAAVTAKKTREFRSPPQEQINMLLNFSAGDDCTCPEELQEELQSFHDDLRLHC GIPMEEEEEEQDTSLKGRLMSLVYKIKGRPQKTEEKPTEQEQAAPTNLKELISQTMVTWA QECKIQDPALVRSMFSLLRRQYDGVGELLRALRKSYTISAKSVGDAINLLASLGQIRSLL SVRMGEEEGQLMIDGLGDIMNNKVFYQHPNLMRVLGMHETVMEVMVNVLGGGKDKEIAFP KMVASCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLACPAMRGSTPLDVAASSVMDN NSLALALEEPDLEKVVTYLAGCGLQNCPMLIARGYPDIGWNPIEGERYLSFLRFAVFVNG ESVEENANVVVKLLIRRPECFGPALRGEGGQGLLAAMKEAIKISEDPALDLPNLPEGAAP IIGEDEEEEEVAHMGNSIMSFYSALIDLLGRCAPEMHLINKGKGEALRIRAILRSLVPTK DLVGIISIPLKMPVVNKDGTVTEPDMNASFCPEHKSPMVLFLDRVYGIDDQSFLMHLLEV GFLPDLRASASLDSEVLRTTETALAMNRYIGSAVLPLLTRCAHLFAHTEHYATLVDSTLH TIYRLSKGRSLTKAQRDAIDECLLAICMHLRPSMLQQLLRRLVFDVPQLSEYCKMPIKLL TNHYEQNWKYYCLPTGLGSYGMASEEELHLTKKLFWGLFDALSQKKYDAELFKMAMPCLS AIAGAIPPDYVDSSPGSALVKQASVDAQGNFDPQPINTANISLPEKLDYIASKFAEHSHE KWSSEKIALGWAAGDKVDDKAKTHPLLKPYKALSEKERETYRYPVKETLKSMLAMGWNIE RTKEGEAMFQQRETEKQRKISESSQGEFIPAPQDLENVILSRELQAMVETVAENYHNIWA KKKKKELDSKGGGSHPLLVPYDTLTAKEKYRDREKAQELFKFLQVNGYAISRGLKDMEQD SSSMEKRIAYKFLKRLLNYVDSAQEFIAHLEALASSGKTEKSPHDQEIKFFAKVLLPVID QYFKNHCLYFLSSPNISLSSSGYASNKEKEMITSLFCKLAALVRHRISLFGSDSTTMVSC LHILSRSLDFRTVMKSGSELVKAGVRTFFENAAEDLEKTLENLKLGKLGQSRTQMKGVTQ IISYTSVALLPILTVLFQHITQHQFGAELLLDDIQLSCYRILTSLYSLGTGKNIYVEKQL PVLGECLSTLVGAMPVAFLESHLNMHNPQSVFNTKTPRERAILSMPDTVDEMCPEMPHLD GIMKDIGDISESGARYSEMPQVIEVILPMLCNYLSYWWEKGPENSPVDTNCCTTVTSEHL SLILGNILKILNNNLGIDNAPWMKRLAVYSQPIISKASPDLLRTHFLPTLEKLKKKTVKV VAEEEMLRAESRADTQEAELQILDEFAVLCRDLYAFYPMLIRYVDNNRSKWLKQPDSDST ELFNMVSEIFILWCKSHNFKREEQNFVVQNEINNLAFLTGDSKTKMSKSGGQDQERRGKR RRGELYSIQTSLIVAAHKKMLPIGLNMCTPGDQELISFAKIRYSLKDTDDEVKDYLRKNL HLQEKSADPAVQWQMNLYRDVVMKNEEPPDPEQNVERVQAISAAVYHLEQVEQPLRNKKM VFQKLLSKQRKRAVVACFRMAPLYNLPRHRSINLFLSGYQRLWIETEEYSFEEKLVQDLA KTPMTVVEEEEEEEAEVQPDPLHQLILHFSHNALTERSFLEEDPLYIAYADMMAKSCAEN EEEEEEEEGKEKTFEEKEMEKQKILYQQARLHARGAAEMVLQMISASKGRLGPMVTGTLK LGISILNGGNVLVQQKMLDYLKEKRDAGFFKSLSGLMMSCSVLDLNAFERQNKAESLGMV TEEGSINVRERGSKVLQNDEFTKDLFRFLQLLCEGHNNDFQNFLRTQTGNTTTVNIIIST VDYLLRLQESISDFYWYYSGKDVMDEAGQLNFSKALAVAKQIFNSLTEYIQGPCIGNQQS LAHSRLWDAVVGFLHVFANMQMKLSQDSSQIELLKELMDLQKDMVVMMLSLLEGNVVNGT IGKQMVDTLVESSSNVEMILKFFDMFLKLKDLTTSDNFKEYDPDCKGVISKKEFQKSMDS QKQYTQSEIEFLLSCVEADENDMFNYKEFVERFHEPAKDIGFNVAVLLTNLSEHMPHDSR LSTFLDLAESVLSYFEPYLGRIEIMGGAKRIERVYFEISESSRTQWEKPQVKESKRQFIF DVVNEGGESEKMELFVNFCEDTIFEMQLASQISEPDAAERPEEDEEEELHSLLEGFSEEE DSSLESASAFTAACASVKKSMSNFRKMLTFKSMKKQFKKFRKLTIREMITGFFSFFWMLF TGFFKGIFGIIFGFFHIIWSSMFGGGLVEGAKNMKVTDILGNMPDPTQFGIHGDVMEAEK TESSELVVSADMVQMTGPGAEKLETDMIMDLLNPAVKKEGKHGAEPGLGDVCEVLESSAP VEKKKSQKAPAEKPESEPEKADTENQEKEDKAKEETPEEPAAAKPAPKAKHGSSKEEAPA FMASFFAGLEVYKAKMLNYLARNFYNLRFLALFVAFAINFILLFYKVTGDFDDEEEEEGS WGGEEEEGDEDDEGMEYFILQESTGYMAPTLTFLAVLHTIISLLCVVGYYCLKVPLVVFK REKEIARKLEFDGLYITEQPSDDDIKGQWDRLVIATPSFPNNYWDKFVKRKVINKYGDLY GAERIAELLGLDKSALDFDPTEEAVVKEASLLSWLSSIDTKYHIWKMGVVLTDNSYLYLI WYTTMSILGHYNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTV VAFNFFRKFYNKSEDEDAPDMKCDDMMTCYLFHMYVGVRAGGGIGDEIEDPAGDPYELYR ILFDITFFFFVIVILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTTPH GFETHTLQEHNLANYLFFLMYLINKDETEYTGQESYVWKMYQERCWDFFPAGDCFRKQYE DQLG NT seq 14595 nt NT seq  +upstreamnt  +downstreamnt atggccgaaggtggcgaaggggaagatgaggttcagttcttacgaactgatgatgaggtg gtgctgcagtgtgtcgctgcaattcagaaggagaatcgcaaattctgcctttcagcagag ggactcggcaaccgcctgtgttatctagagcccacatcagaggcaaagtattttcctcct gacctatgcatctgtaactttgtgctggagcagtcgctctcagtgcgggctctgcaggag atgctcgccgggcagagcggtgaaggaaatcctgatcatgagcaatgggcagcacaggga ggtggacatcggacactgctctacggtcacgccatcctccttaggcattccttcagtgga atgtatctcacatgcctaaaaacttccaggtctctgacagacaagctgtcttttgatgtg ggccttcaggaggattcaacaggggaagcttgttggtggacaattcacccggcttccaag cagaggtcagagggtgagaaggtgcgcattggagatgacctcatcttggtcagcgtatcc tctgagaggtacctgcacctctccatctccaatggaagtattcaagtggatgcttcattc atgcaaacactgtggaatgttcagcctacctgctccagaagcaacatggaagtgggattt ctcctgggtgggcatgtgatgcgcttattccacgggcacgatgagagcctcaccatacca ggatctgagcaaagccaagagcaacagagagtggtaaactatgagacaggcaaaggaggg tccaaggccaggtctttatggagactggagcctcttcggataagctggagcgggagtcac atcagatggggtcagcctttccgtctccgccatctctccaccggtcactacctgggccag acagaggacaatggcctgatactgctggacagagagaagtctgataccactgctacagcc ttctgtttccggtcaagcaaggaaaagattgactccggcccaaagcgtgatattgatggt atgggggtggcggagatcaaatacggcgattccgtctgcttcatcatgcatgtgtccacg ggcctgtggttgtcctaccaggcgcctgatgccaaatcttctcgcctgggaccactgaag agaagggccgtcctttctcttgagggccatatggatgatgggctgactctgcagctttgc cagcacgaggagtcccgagcggctcgcatcattcgtaataccactcgcctcttcactcag ttcatcaggggtctggatggtttgaatggggagaaaactacagaggtgaccctgcctgtg tgtgaagtgctgcagacactagacgacctcattgtgtactttcagcagcctgactctgag ctcgaacatgaggagaaacagaggcagctccgatctctcatcaagcgccaagatctcttc aaagaagagggaatgcttaccctggtctctcactgcatcgatcgtctaaacgtgtacaac agtgctgctgagtttgaggagttagcaggcgaggaggccggagaggcctggaaggacatt ctcaaccttctctatgagcttctggctgctctgattcgaggcaacaggaccaactgcaca cagttctctcgcaagctggattggctggtcagcaagctcgagcgattggagtcctcatca ggcattttagaggtgcttcatagtatcctaatcgagagtccagaatctctgaacatcatc cagaaggcccacatcaaatccattatttctctgctatacaagcatggacgcaaccacaag attctagatgttctctgctctctgtgtgtctgcaatggtgtggctgtgagagccaatcag aacttcatctgtgaccacctgcttcccaggagagacctgctgctccagacacgattggtc aatgatgtccaaagtatgagacccaacatcttcctgggcatgagtgagggctcggcacag tataggaaatggtactttgagctgatcatcgatcaagtagaccactatgtgaccagtgag cccacccaccttcgtgttggctgggccaccaccaaaggctacgccccctatcctgggggt ggagagggctggggagggaacggtgcgggtgacgatctttactcctacagttttgatggg cttcatctgtggtcagggcgaatcccacgggccgtggcctctattaaccagcacttgctg aattcagacgatgttgtgagctgctgtctggatctcggagcccctagcatgtctttccga attaacggtcagcccgttcaaggcatgtttgaagacttcaacgtagatggcttcttcttt cccgtcgtcagtttctctgcaggggtgaaagtccgtttcctgttgggtggacgccatgga gactttaagttcctgcctccagcaggctatgcaccatgttatgaagccctgctccccaaa gaaaagatgcgtgtggagcctgtgaaggagtataaaagagatctggagggagttagagat ctgctgggcaccacagagttcctctcccaggcttctttcattcctgttcctgttgatacc agccagattgtcctgcctccccatcttgaaaatgtgcgggacaagttagctgagaacatc catgagctctggggcatgaacaaaatagagcttggctggatgtacggcaaggttcgagat gacaacaagagacagcacccttgtcttgttgatttctctaaactgccagaaacagaaaag aattataacctgcaaatgtcaactgaaactttgaagaccctacttgctttgggatgccat gttgcacaagtcaatataaatgctgaagatgacctgaaaaaaatgaaactccccaagaac tatatgatggctaatggctataaacctacaccactagacctttctgatgtgaaactgaca cctggtcaggaggttttagttgataaactggctgaaaatgctcataatgtttgggccaag gatcgcattaaacaaggatggacctatggtattcagcaggatttgaaaaaccgtcgtaat ccacgactggtaccatatgctttattagatgaacgcactaaaaaatcgaacagagacagt cttcgagaggccatccgtactctggttggatatggatatttcatagaccctcctgatcaa gagactgctcatactgtagagaaggagggcattgaatccatccgtctctttcgtgtggag aagacctacgctgtgaagacaggaaagtggtattttgagtttgaggcgctcactggaggt gacatgcgggtgggctgggcacggcccggatgcagacccgatatggaactgggactggat gaccagtccttcgtctttgatggctacaggggccgtcgggttcatatgggcagtcatttc tttgggaggacatggactaaaggagatgtggtgggctgcatgatcaacatggaggacaaa tccatgatattcaccctgaatggagagatcataatcaccaacaagggttctgagctctgc tttgctgactttgaagctgaagatggattcatcccagtctgcagccttggtctttcccaa attggtcgcatgaatttaggaaaagacgctagtacttttaagtactacaccatgtgtggc cttcaagaaggctttgaaccctttgctgttaacatgaatcgagaagtcactatgtggttc agcaaacgcctgcctacatttgttaatgtaccagaggaccatccccatattgaggttact agaatagatggcactgtggatacacctccatgtctaaaggtgacacacaaaacatatggg acccagaccagcaatgatgacatggtctgctgtcgtctaagcatgcctgttgagtttcac tctggccctcggaagatcactgatatcaatgaggtgatcgctgaggaccaaagagctaag aaggatgatagtggcaagattgattatggcagcattacaaagtacttctactctgtgaga gtcattgctggacaagatccatcatctgtttgggtgggctgggtgacaccagactatcac tactacagcaagcaattcatgctcagcacagttcgcaccgtcactgtaacgctgggagac gagcggggacgtgttcatgagagtgtaaggaggagtaattgttacatggtctgcgctggg gatgttgtcaacagctccacaggccgtagtaacactgatttggagattggctgctccata gatctggcctcaggcctggtctcattcactgccaatggcagagacctgcctacggcatac caggttgagcctaacactaagctcttccctgctgtgtttgttcaacccacgagtcccaac ctcttccagtttgagtttccaaaaatcccagatgcaatgcccctgtcttcagccatcttt aagagtttacaaagaaacccagagccacagtgtcctcctcggctggacgtgcagacaatt gtgtccgtgttgtggagcagaatgcccaacaccttcctgacagtggagacggcccgtgtc agtgagaggcatggctgggtgttgcagtgtctggaacccctgcagatgatggctgttcat atcccagaggagaacaggtgtatcgacatcatggaactatcagaaaacgaagatctaagg cagttccactatcacacattaaagctcttctgtgcactttgcgcattgggcaacacccgc gttgctcacgccctctgtagccatcttgaccaatcacagctcctgtataccattgataac cagtacctgtctggtcagctgcgtgaaggcttttacaatgtcctcatcagcattcacctg gagacgggcaaagaggcccatcttatgatgaacaatgagtttataatcccagtaacagat gagacaaggagcatccgcctcttccctgacgactctaagtgtcactctcttcctggcgta ggcttgagcacttcgctgacccctcgcctctacttcacccctccgtatttcataaccccc aagcgcgatcagcccctcttcagtccccagatccccctgggtatcctgaaggagaaagcc atcagtatgcttacagaagccgtgcagggtggaggcgcccacattcgagatcctgtgggc ggaagcgttgagtatcagtttgtgccgattctcaggctgattggcacactgttgataatg ggagcgatgaccagcgaggaggtgaggaccatcttgcttctcgttgatcccattgtgttt ggggatggtaaggaagaggaggagcaagtggcagtggtggaacagggagcggagaaagag gaggccgccagtaatgaagagaaagctgtggaggccggagaggaggagagtaaagaggcc aagcagtctcccaaaggtcttctagagaaaagcttgcctgagtcggtcaaacggcagatg tgtgaactgctgcactatttctgtgactgtgagctgaagcagcgcattgaggctatagtg gccttctcagatgattttgtgtccaagctgcaattcaatcagaagttccgctacaatgag ttgatgcaagccctgaacatgtcagctgctgtcactgccaagaagacaagagagttccgc tcacctccccaagagcagataaacatgttgttgaacttcagtgctggtgatgattgcacc tgccctgaagagctgcaagaggagcttcaaagcttccacgatgacctgcgactacattgt ggcatccctatggaagaggaagaggaggagcaggacacatctcttaaaggccgcctaatg tccttggtatacaagattaaaggtcgtccccaaaaaactgaggagaaaccaacagagcaa gaacaggccgctcctaccaacctgaaggagctgatatctcagactatggtcacctgggct caggagtgcaagattcaagacccggcactggtccgcagcatgttcagccttttgagaagg cagtatgatggcgtcggtgagctactcagggccttgaggaagagctacaccatcagtgcc aagtctgtaggggacgcaatcaacctgctggcctcactgggccagatccgttcactactt agtgtccgtatgggtgaagaggagggtcagcttatgatcgacgggctgggggacatcatg aacaacaaagtgttttaccagcatccaaatctgatgcgtgttcttggcatgcatgagaca gtaatggaggtcatggtcaatgtgctgggaggaggcaaggataaggagattgccttcccc aagatggtggccagctgttgtcgcttcctgtgctacttctgtcgcatcagccgtcagaac cagaaggctatgtttgaccacctgagctacctcctggagaacagcagtgttgggctggct tgtccagccatgagaggctctacacctttagatgtggccgcctcctctgtgatggacaac aacagtttagctcttgcgcttgaggaacctgatcttgagaaggtggtgacatatctggca ggctgtggcttacagaactgcccgatgctcattgccaggggatacccagacattggctgg aacccaatcgaaggagagcgctatttatccttcctacggtttgctgtctttgtcaacggc gaaagtgttgaagagaacgctaatgtagtggtaaagcttttgattaggcgcccggagtgt ttcgggcctgcgctcagaggagagggagggcaaggtttacttgctgccatgaaggaagcc atcaagatctcagaagatcccgctttggacctgcctaacttaccggagggggctgcaccc atcatcggagaggatgaagaggaggaggaggtcgcccacatgggcaactctattatgtct ttctactcagcccttattgatcttctgggccgctgtgcacctgagatgcatcttataaac aaaggcaaaggcgaagcactgcgtatccgtgccatcctccgttccttagttcccactaaa gatttggtgggaattatcagtattccactcaaaatgccggtcgtcaataaagatggcact gtgacagagccagatatgaatgccagcttctgtccggagcacaagtcacccatggtgctt ttcttggaccgtgtctatggtattgacgaccagagcttcttgatgcacctgctggaggtg ggcttcctgccagacctgcgagcatcagcctccctggactcggaggtgctcaggaccaca gaaacagccctggccatgaaccgctacattggatccgcagtgcttccactgttgacccgc tgtgctcatctgttcgctcacaccgagcactatgcgacactcgttgactctacgctgcac accatctatcgcctctcaaagggccgatcactcaccaaggcccagagagatgctattgat gaatgtctactggccatctgcatgcatctgaggccatcaatgctacagcaacttttgcgt cgtcttgtgtttgatgttccccagctttcagagtactgcaagatgcccattaagctgttg accaatcactatgagcagaactggaagtactactgtctgccaacaggcctgggcagctat ggaatggcatcggaggaggaactccacctcaccaagaaactcttctggggactttttgat gctctttctcaaaagaaatatgatgcagagctttttaaaatggccatgccatgtctgagt gccatagctggtgccataccacctgattatgttgactccagcccgggctccgcattagtt aagcaggcctctgtggatgcacaaggcaacttcgacccccagcctattaacactgcaaac atctcgctacctgaaaagctagattatatagcaagcaagtttgctgagcattcccatgag aaatggtcctctgagaagatcgctctcggctgggctgcgggagataaagtagatgacaaa gctaaaactcatccacttctgaaaccgtacaaagcactgagtgaaaaggaaagggagacg taccgctatcctgtgaaagagactctgaagagcatgttggcaatgggatggaacattgag aggaccaaagaaggagaagccatgttccagcaaagagaaacagaaaaacagcgcaagata tcagagtcctctcagggcgagtttattccagccccacaagatttggaaaatgttattcta tcaagagaacttcaggcaatggttgaaacagtcgcagaaaattaccacaacatttgggca aagaagaagaaaaaggaacttgacagtaaaggaggaggaagtcatccattgttggtaccg tacgacacactgactgcaaaggagaagtacagagatcgagagaaggcccaggaactcttt aaattcctgcaggttaatggatatgccatcagcagaggtctgaaggacatggagcaggat tcctcttctatggaaaagaggattgcctacaagttcctcaagaggctcttgaattatgtg gattctgcacaggagtttatcgcccaccttgaggctttggcaagcagtggaaagacagaa aaatctccccatgatcaagaaatcaagttttttgctaaggttctgctgcccgtcatagac cagtacttcaaaaaccactgcttgtacttcctgtcatctcccaacatcagcctgagcagc agtggctacgcatccaacaaagagaaggagatgatcaccagtctattctgtaagctggca gcccttgtcaggcatagaatatcactctttggaagtgactccaccaccatggtgagctgt ttgcacatcctgtcacgctcactggactttaggactgtgatgaagtctggctcagagttg gtgaaggctggtgtcaggacgttctttgagaatgcagcagaagacctggagaagacattg gagaacttaaagctggggaagttgggtcagtcacgcacccagatgaaaggcgttacccag atcatcagctacacttcagtggccctgctgcccatcctgacggttctctttcagcatatc acccaacaccagtttggagcagagctgctattggatgacattcagctgtcttgctaccgc atcctgaccagcctctactctttgggcactggcaagaacatctatgtggaaaagcagctt ccagtgcttggtgaatgtttatccacactggtgggagccatgcctgttgccttcctggaa tcccacctaaatatgcacaacccccaatctgtcttcaacaccaagacaccaagagaacga gctattttgagcatgccagacactgtggatgagatgtgtcctgagatgccccatttggat ggcataatgaaggacattggcgacatttctgaatctggagcacgctactcagagatgcca caggtcattgaggtcatcctgccaatgttgtgtaactacctgtcttactggtgggaaaaa ggcccagaaaactctccagttgataccaattgctgcacaactgtcacatctgagcatctc agcctaatcctgggcaatatccttaagattctcaataacaaccttggcattgataatgcc ccttggatgaaaagacttgcagtatactcccagcctatcattagcaaggctagcccagat cttcttagaacacacttcctgcctacgctggagaaattgaagaagaaaaccgtgaaggtg gtggctgaagaggagatgttgagggctgaaagcagggcagacactcaggaagctgaactg cagattctggatgagtttgctgttctctgcagggatctgtatgccttctatccaatgcta attcgttatgtggacaacaacagatccaaatggctgaagcaaccagattcagattcgact gaacttttcaatatggtgtcagagattttcatcctttggtgtaaatcccataactttaaa agggaagagcaaaattttgtggtgcaaaatgaaattaacaacctggcgttcctcactgga gacagcaagacgaagatgtcaaaatctggaggtcaggaccaagagagaagaggaaaaagg agaagaggagagttgtactccatccagacttctcttatcgtagcagctcataagaagatg ttgcctattggtctgaacatgtgcactcctggagaccaggagctcatctcctttgccaag attcgttatagtctgaaagacacagatgatgaggttaaggattacctgagaaagaacctc catcttcaggagaagtcagcagatccagcagtacaatggcagatgaacctctacagagat gttgtgatgaagaatgaggaacctccagacccagagcaaaatgtggagagagttcaggcc atttccgctgctgtctaccaccttgaacaggttgagcagcccctgaggaacaagaagatg gtgtttcaaaagctgctgtcaaagcaaagaaagcgtgccgtggtggcctgtttccgcatg gcaccactctacaacttaccaaggcatcgctcaattaacctcttcctcagtggctatcag agactttggatagagacagaggagtactcctttgaggagaagctagtgcaggacctggca aaaacacccatgactgtggtagaggaagaagaggaagaagaagctgaagttcagccagac cctcttcatcagctcatccttcacttcagtcacaatgctttgacggagagaagttttctt gaagaggatcctctttacattgcatatgctgacatgatggcaaagagctgtgctgagaat gaagaagaagaagaggaagaggaaggaaaagaaaaaacttttgaggaaaaagaaatggag aagcagaagattctgtaccagcaggccagacttcatgctcgtggagctgctgagatggtg ctacagatgatcagtgccagcaaaggtcgacttggtcctatggtgactggcacccttaaa ctgggcatttcaatcctaaatggaggcaacgttcttgtccagcagaaaatgctggattat ttgaaggaaaaacgagatgcaggcttctttaaaagtttatctggactaatgatgtcttgc agtgtgctggatttaaatgcatttgaaagacaaaataaggcagagagtcttggaatggtg actgaagaggggtcaatcaacgtgagagagcggggttcaaaagtactgcaaaatgatgaa tttacaaaggatctattcaggtttttgcaacttctatgcgaggggcacaataatgatttc caaaacttcttgcggacccagactggaaacaccactacagtcaacatcatcattagtact gtggactacctactacgtctacaggaatctataagtgatttttactggtattactctggg aaagatgtcatggatgaggctgggcaacttaacttttccaaagctttggcagtagccaaa caaatctttaactcactcactgagtacattcagggcccttgtataggcaatcagcaaagt ttggcacacagcaggttgtgggatgcagtggtcgggttcttgcatgtttttgccaacatg caaatgaaactgtcacaggattctagtcaaatcgagttattgaaagagctgatggatttg cagaaagatatggtggtcatgatgttatctcttctggagggtaatgtggtgaatggaact attggcaagcagatggttgacacattagtggagtcctccagcaacgtggaaatgatcctc aagttcttcgacatgttcctcaaacttaaggacctcactacatctgataacttcaaggag tacgacccagattgcaaaggcgttatatccaagaaggagttccagaagtctatggatagc caaaagcaatacacacagtctgagatcgagtttctcctctcctgtgtggaggcagatgaa aatgatatgttcaactacaaggagtttgtggaacgcttccatgaaccagccaaggacatc ggcttcaacgtggctgtgcttcttactaacttatcagagcatatgcctcacgactcacgc ctgtccaccttcttagacctggctgaaagtgttctcagctactttgagccctacctgggc cgtattgagatcatggggggtgccaagaggatcgagagggtttactttgagatcagtgag tctagcagaacccaatgggaaaagcctcaggtcaaagaatccaaacggcaattcatcttt gatgtggtcaacgaaggcggtgagagtgagaagatggagttatttgtgaacttctgtgag gacaccatctttgaaatgcagttggcctctcagatctcggagccagacgcagcagaacgg cctgaggaggacgaagaagaggagttgcatagtctgcttgagggattttctgaggaggaa gactcatctcttgagtctgcctctgccttcactgcagcctgtgcttcagtgaagaagagc atgtctaatttccgtaaaatgctgacatttaagagtatgaagaaacagtttaagaaattc aggaagcttaccattagggaaatgatcacagggttcttctccttcttctggatgctcttc actgggttcttcaaaggcattttcggcatcatctttgggttcttccatatcatttggtcc tccatgttcggagggggtcttgtggagggagctaaaaacatgaaagtgacggatatcttg ggtaacatgcctgatccaacacagtttgggatccatggtgatgttatggaagcagaaaaa actgagagcagtgagttggtggtgtcagcagatatggtccagatgactggtcctggtgct gagaagctggaaaccgatatgatcatggatctacttaatccagctgtgaagaaggaggga aagcatggggcagaacctggtctgggtgatgtctgtgaagtcctagagtctagtgcccct gttgagaaaaagaagagccagaaagcaccagcagagaagccagaatccgagccagagaaa gctgacactgagaatcaggagaaagaagacaaggctaaggaggaaactcctgaggaacca gcagcagcaaaaccagctccaaaagccaaacatggttcatcaaaggaagaagctccagcc ttcatggccagcttctttgcagggcttgaagtctacaaagccaaaatgctcaactacctg gctcgcaatttctacaaccttcgttttctggccttgtttgtggccttcgccatcaacttc atcctgctcttctacaaggtgactggagattttgatgatgaggaagaggaggagggatcc tggggtggtgaagaggaggaaggtgatgaagacgacgaaggaatggagtacttcattctt caggagagcactggctacatggcacccaccctgacgttcttggctgtgctgcacacgatc atttccttactctgtgtcgttggatattactgccttaaggttcctttagttgtgttcaaa cgtgagaaggagattgctaggaaacttgagtttgatggcttgtatattaccgagcagcct tctgatgatgacatcaaaggacagtgggatcgtttggtcattgcaactccgtccttccct aacaattactgggacaaatttgttaagaggaaggtcatcaataaatatggtgacttgtat ggggccgagcgcatagctgagctcctggggctggataagagtgctctggactttgacccc accgaagaggccgtggtgaaggaggcctcccttctgtcctggttgagctcaattgatacc aagtaccacatctggaaaatgggggtggtgctgacggacaactcttacctctacctgatc tggtacaccactatgtctattctgggacattacaataacttcttctttgccgctcatttg ctggacattgccatgggcttcaagaccttaaggaccatcctgtcttctgtgactcataat ggcaaacagctggtgttgaccgtgggcctcctggcggttgtggtctacctctacaccgta gtggcttttaacttcttccgcaagttctacaacaagagcgaggatgaggacgcacctgac atgaagtgtgatgatatgatgacttgctacctgttccacatgtacgtgggtgtgagagct ggcggtggcatcggtgatgaaatcgaggacccggccggcgacccgtacgagctctaccgc attctgtttgacatcaccttcttcttcttcgtcatcgtcattctgctggccatcattcag ggtttgatcattgatgccttcggtgagctgagagaccagcaggagcaggtgaaagaggat atggagacaaaatgcttcatctgcggaatcgggaatgactattttgatacaactccacac ggctttgagacccataccctacaagagcacaatctggccaactatttattcttcttgatg tatcttatcaacaaggatgagactgaatatactggtcaggagtcttatgtttggaagatg tatcaggagagatgctgggatttcttccctgctggagactgtttccggaagcaatacgag gaccagctgggctag

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