Panthera tigris altaica (Amur tiger): 102949810
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Entry
102949810 CDS
T02988
Symbol
SDHA
Name
(RefSeq) succinate dehydrogenase complex flavoprotein subunit A
KO
K00234
succinate dehydrogenase (ubiquinone) flavoprotein subunit [EC:
1.3.5.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg00020
Citrate cycle (TCA cycle)
ptg00190
Oxidative phosphorylation
ptg01100
Metabolic pathways
ptg01200
Carbon metabolism
ptg04714
Thermogenesis
ptg04932
Non-alcoholic fatty liver disease
ptg05010
Alzheimer disease
ptg05012
Parkinson disease
ptg05014
Amyotrophic lateral sclerosis
ptg05016
Huntington disease
ptg05020
Prion disease
ptg05022
Pathways of neurodegeneration - multiple diseases
ptg05208
Chemical carcinogenesis - reactive oxygen species
ptg05415
Diabetic cardiomyopathy
Module
ptg_M00009
Citrate cycle (TCA cycle, Krebs cycle)
ptg_M00011
Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
ptg_M00148
Succinate dehydrogenase (ubiquinone)
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
102949810 (SDHA)
09102 Energy metabolism
00190 Oxidative phosphorylation
102949810 (SDHA)
09150 Organismal Systems
09159 Environmental adaptation
04714 Thermogenesis
102949810 (SDHA)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
102949810 (SDHA)
09164 Neurodegenerative disease
05010 Alzheimer disease
102949810 (SDHA)
05012 Parkinson disease
102949810 (SDHA)
05014 Amyotrophic lateral sclerosis
102949810 (SDHA)
05016 Huntington disease
102949810 (SDHA)
05020 Prion disease
102949810 (SDHA)
05022 Pathways of neurodegeneration - multiple diseases
102949810 (SDHA)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
102949810 (SDHA)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
102949810 (SDHA)
Enzymes [BR:
ptg01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.5 With a quinone or related compound as acceptor
1.3.5.1 succinate dehydrogenase
102949810 (SDHA)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
FAD_binding_2
Succ_DH_flav_C
Pyr_redox_2
Thi4
GIDA
DAO
FAD_binding_3
HI0933_like
Motif
Other DBs
NCBI-GeneID:
102949810
NCBI-ProteinID:
XP_007087339
UniProt:
A0A8C9M2N1
LinkDB
All DBs
Position
Un
AA seq
665 aa
AA seq
DB search
MSGVRAVPRLLGARRLALTRAQWPATWQAGTCGFHFTIDGNKRSSAKVSDSISAQYPVVD
HEFDAVVVGAGGAGLRAAFGLSEAGFNTACVTKLFPTRSHTVAAQGGINAALGNMEEDNW
RWHFYDTVKGSDWLGDQDAIHYMTEQAPASVVELENYGMPFSRTEDGRIYQRAFGGQSLK
FGKGGQAHRCCCVADRTGHSLLHTLYGRSLRYDTSYFVEYFALDLLMENGECRGVIALCI
EDGSIHRIRAKNTVVATGGYGRTYFSCTSAHTSTGDGTAMVTRAGLPCQDLEFVQFHPTG
IYGAGCLITEGCRGEGGILINSQGERFMERYAPVAKDLASRDVVSRSMTLEIREGRGCGP
EKDHVYLQLHHLPPEQLAIRLPGISETAMIFAGVDVTKEPIPVLPTVHYNMGGIPTNYKG
QVLRHVNGQDQIVPGLYACGEAACASVHGANRLGANSLLDLVVFGRACALSIAESCRPGD
KVPPIKPNAGEESVMNLDKLRFADGTLRTSELRLNMQKSMQNHAAVFRVGSVLQEGCEKI
SQLYGDLKHLKTFDRGMVWNTDLVETLELQNLMLCALQTIYGAEARKESRGAHAREDYKE
RIDEYDYSKPIQGQQKKPFEEHWRKHTLSYVDIKTGKVSLEYRPVIDRTLNEADCATVPP
AIRSY
NT seq
1998 nt
NT seq
+upstream
nt +downstream
nt
atgtcgggggtccgggcggtgccgcggctgctgggcgcccggcgcctggcactgactagg
gcgcagtggcccgcgacatggcaggcaggcacctgcggttttcacttcactattgatggg
aataagaggtcttcagctaaagtttcagattcaatttctgcgcaatacccggtagtggac
cacgaatttgatgcggtggtggtaggcgctggaggggcaggcctgcgagctgcgtttggc
ctttccgaggcagggtttaacacggcctgcgtcacaaagctctttcctacgagatcacac
accgtcgcagcccagggagggatcaatgctgctctggggaacatggaggaggacaactgg
aggtggcacttctacgacactgtgaaaggctccgactggctgggggaccaggatgccatc
cactacatgacagagcaggcccctgcttccgtggtagagctggagaattatggcatgcca
ttcagcagaactgaagatgggaggatctaccagcgtgcttttggtggacagagcctcaag
tttgggaaaggcgggcaggcccatcggtgctgctgtgtggctgaccgcactggccactcg
ctgctgcacacgttgtatggaaggtctctgcgatatgataccagctattttgtagagtat
tttgccttggatctcctgatggaaaatggagaatgtcgtggtgttattgcgctgtgcata
gaagacgggtccatccatcgcataagagcaaagaacactgttgtagctactggaggctac
gggcgcacctacttcagctgcacatctgcccacaccagcaccggtgacggcaccgccatg
gtcaccagggcaggccttccctgccaggacttggagttcgttcagtttcaccccacaggt
atatatggtgccggttgtctcattacagaagggtgccgtggagagggaggcattctcatt
aacagtcaaggcgaaagattcatggagcgatatgccccggttgcaaaggacctggcatcc
agagacgtcgtgtctcggtccatgactctggaaatacgtgaaggaagaggctgtggccct
gaaaaagatcacgtctacctgcagttgcaccacctacccccagagcagctggccatacgg
ctgcctggcatttcagagacggccatgatcttcgcaggtgtagatgtcaccaaggagccc
atccccgtccttcccaccgtgcattataacatgggcggcattcccaccaactacaagggg
caggttctgaggcatgtgaatggccaggatcagatcgtgcccggcctgtatgcctgtggg
gaggctgcctgcgcctccgtgcatggtgccaaccgtcttggggcaaactcactcttggat
ctggttgtctttggtcgggcgtgtgccctgagtatcgcggagtcctgcagacccggagat
aaagttcctccaattaaaccaaatgctggagaagagtctgtcatgaatcttgataagttg
aggtttgctgatggaaccctaagaacatcagaactacgactcaacatgcagaagtcgatg
caaaatcatgccgcagtgttccgtgtgggaagtgtgttgcaggaaggttgtgagaaaatc
agccagctctatggagacctaaaacatctgaagacatttgaccgaggaatggtctggaac
accgacctggtggagaccctagagctgcagaacctgatgctttgtgcacttcagaccatt
tatggagcggaggctcggaaggagtcacgtggtgctcatgccagggaagattataaggag
cggattgacgagtatgattactccaagcccatccaggggcagcagaagaagccatttgag
gaacactggaggaagcacaccctttcctatgtcgacatcaagactgggaaggtctccttg
gagtacagacccgtcattgacagaactttgaatgaggcagactgtgccacagtccctcca
gccattcgctcctactga
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