Panthera tigris altaica (Amur tiger): 102950188
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Entry
102950188 CDS
T02988
Symbol
ERBB4
Name
(RefSeq) erb-b2 receptor tyrosine kinase 4
KO
K05085
receptor tyrosine-protein kinase erbB-4 [EC:
2.7.10.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04010
MAPK signaling pathway
ptg04012
ErbB signaling pathway
ptg04020
Calcium signaling pathway
ptg04151
PI3K-Akt signaling pathway
ptg05014
Amyotrophic lateral sclerosis
ptg05205
Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
102950188 (ERBB4)
04012 ErbB signaling pathway
102950188 (ERBB4)
04020 Calcium signaling pathway
102950188 (ERBB4)
04151 PI3K-Akt signaling pathway
102950188 (ERBB4)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
102950188 (ERBB4)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
102950188 (ERBB4)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102950188 (ERBB4)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
102950188 (ERBB4)
Protein kinases [BR:
ptg01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
102950188 (ERBB4)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
GF_recep_IV
Recep_L_domain
Pkinase
Furin-like
TM_ErbB1
Kinase-like
Haspin_kinase
ABC1
Motif
Other DBs
NCBI-GeneID:
102950188
NCBI-ProteinID:
XP_015394761
LinkDB
All DBs
Position
Un
AA seq
1231 aa
AA seq
DB search
MWKLKLFVSFQSIREVTGYVLVALNQFRYLPLENLRIIRGTKLYEDRYALAVFLNYRKDG
NFGLQELGLKNLTEILNGGVYVDQNKFLCYTDTIHWQDIVRNPWPSNLTLVSTNGSSGCG
RCHKSCTGRCWGPTENHCQTLTRTVCAEQCDGRCYGPYVSDCCHRECAGGCSGPKDTDCF
ACMNFNDSGACVTQCPQTFVYNPTTFQLEHNFNAKYTYGAFCVKKCPHNFVVDSSSCVRA
CPSSKMEVEENGIKMCKPCTDICPKACDGIGTGSLMSAQTVDSSNIDKFINCTKINGNLI
FLVTGIHGDPYNAIEAIDPEKLNVFRTVREITGFLNIQSWPPNMTDFSVFSNLVTIGGRV
LYSGLSLLILKQQGITSLQFQSLKEISAGNIYITDNSNLCYYHTINWTTLFSTINQRIVI
RDNRKAENCTAAGMVCNHLCSSDGCWGPGPDQCLSCRRFSRGRSCIESCNLYDGEFREFE
NGSICVECDPQCEKMEDGILTCHGPGPDNCTKCSHFKDGPNCVEKCPDGLQGANSFIFKY
ADQDRECHPCHPNCTQGCIGSRIEDCIGLMDRTPLIAAGVIGGLFILVIVGLTFAVYVRR
KSIKKKRALRRFLETELVEPLTPSGTAPNQAQLRILKETELKRVKVLGSGAFGTVYKGIW
VPEGETVKIPVAIKILNETTGPKANVEFMDEALIMASMDHPHLVRLLGVCLSPTIQLVTQ
LMPHGCLLDYVHEHKDNIGSQLLLNWCVQIAKGMMYLEERRLVHRDLAARNVLVKSPNHV
KITDFGLARLLEGDEKEYNADGGKMPIKWMALECIHYRKFTHQSDVWSYGVTIWELMTFG
GKPYDGIPTREIPDLLEKGERLPQPPICTIDVYMVMVKCWMIDADSRPKFKELAAEFSRM
ARDPQRYLVIQGDDRMKLPSPNDSKFFQNLLDEEDLEDMMDAEEYLVPQAFNIPPPIYTS
RARIDSNRSEIGHSPPPAYTPMSGNQFVYRDGGFAAEQGVPVPYRATTSTIPEAPVAQGA
TAEIFDDSCCNGTLRKPVAPHVPEDSSTQRYSADPTVFAPERSPRGELDEEGYMTPMRDK
PKQEYLNPVEENPFVSRRKNGDLQALDNPEYHNASNGPPKAEDEYVNEPLYLNTFANALG
NAGYLKNNVLSVPEKAKKAFDNPDYWNHSLPPRSTLQHPDYLQEYSTKYFYKQNGRIRPI
VAENPEYLSEFSLKPGTVLPPPPYRHRNTVV
NT seq
3696 nt
NT seq
+upstream
nt +downstream
nt
atgtggaaattaaaattgtttgtgtcttttcagtctattcgagaagttacaggctacgtg
ttagtggctcttaatcagtttcgctacctgcctctggagaatttacgcattatccgtgga
acaaaactttatgaggatcgatatgccttggcagtatttttaaactacagaaaagatggg
aactttggacttcaagagcttggactaaagaacttgacagaaatccttaatggtggagtc
tatgtagaccagaacaaatttctttgttacacagacacaattcattggcaagatattgtt
cggaatccgtggccttccaacttgactctggtgtcaacaaacggtagctcaggatgtgga
cgttgccataagtcctgtactggccgatgctggggacccacagaaaatcattgccagacc
ttgacaaggacggtgtgtgcagaacagtgtgacggcaggtgctatggaccctacgtcagt
gactgctgtcatagagaatgtgctggaggttgctcaggaccaaaagacaccgactgcttt
gcctgcatgaatttcaatgacagtggagcgtgtgttactcaatgtccccaaacttttgtc
tacaatccaaccacttttcagctggaacataacttcaatgcaaagtatacatatggagca
ttttgtgtcaagaaatgcccacataactttgtggtggattccagttcttgtgtgcgtgcc
tgccctagttccaagatggaagtggaagaaaatgggattaaaatgtgtaaaccttgcact
gatatttgcccaaaagcttgtgatggcattggcacaggatcactgatgtcagctcagacc
gtggattccagtaacattgacaaattcataaactgcaccaaaatcaatgggaatttgatc
ttccttgtcactggtattcatggggacccttacaatgcaattgaagccatagacccagag
aaactgaatgtctttcggaccgttcgagagataacaggtttcttgaacatacagtcatgg
cctccaaacatgactgacttcagtgttttttctaacctggtgaccattggtggaagagta
ctctacagtggcctctccttgcttatcctgaaacaacagggcatcacttctctacaattc
cagtccctgaaggaaatcagtgcaggaaacatctatattactgacaacagcaacctatgt
tattatcataccattaattggacaacactcttcagcactatcaaccaaagaatagtgatc
cgggacaacagaaaagctgaaaactgtactgctgcaggaatggtgtgcaaccatctgtgt
tcaagtgatggctgctggggacctggcccagaccaatgcctgtcctgccgtcgcttcagc
agaggaaggagctgcatagagtcttgtaacctctatgatggtgaatttcgagagtttgag
aatggctccatctgtgtggagtgtgacccccagtgcgagaagatggaagacggcatcctc
acatgccatggaccgggacctgataactgcacaaagtgttcccattttaaggatggcccg
aactgtgtggaaaaatgtccagatggcttgcagggggcaaacagtttcattttcaagtat
gctgatcaggatcgagagtgccatccatgccatccaaactgcacccaagggtgcataggc
tcacgtattgaagactgcatcggcctgatggatagaactcctctaattgcagctggagtc
atcggcgggctcttcatcctggtcatcgtgggtctaacatttgcagtttatgtaagaagg
aagagtatcaaaaagaaaagagccctgagaagatttctggaaacagagttggtagaaccc
ttaactcccagcggcacagcacccaatcaagctcaactgcgtattttaaaagaaactgag
ctcaaaagagtgaaagtacttggctcgggagcttttggaacagtgtataaaggtatttgg
gtacctgaaggagaaacagtaaagattcctgtggctattaagattcttaatgaaacaact
ggtcccaaagccaatgtggagttcatggatgaagctttgatcatggcaagtatggaccat
ccacacttagtccggttattgggtgtgtgtctgagcccaaccattcaactggttacacag
cttatgccccatggctgcctgttggattatgtacatgaacataaggataacattggatcc
cagctactgcttaactggtgtgtccaaatagctaagggaatgatgtacctggaggaaaga
cggcttgttcatcgggatttggcagcccgaaatgtcttagtgaaatctccaaaccatgtg
aaaatcacagattttggactagctaggctcttagaaggagatgaaaaagagtataatgct
gatggaggaaagatgccaattaaatggatggctctggagtgtatacactacaggaagttc
acccatcagagtgatgtttggagttatggagttaccatatgggaactgatgacctttgga
ggaaaaccctatgatggaattccaaccagagaaatcccggatttattagagaaaggagaa
cgtttgccccagcctcctatctgcactattgacgtttacatggtcatggtcaaatgctgg
atgattgatgcagacagtagacctaaatttaaggaactggctgctgaattttcgaggatg
gctcgagaccctcaaagatatctagttattcagggtgatgatcgcatgaagcttcccagt
ccaaatgacagcaagttctttcagaatctcttggatgaagaggacctggaagatatgatg
gatgctgaggaatacctggtccctcaggctttcaacatcccacctcccatctatacttcc
agagcaagaattgactcaaataggagtgaaattggacacagccctcctcctgcctacacc
cccatgtcaggaaaccagtttgtataccgagacggggggtttgctgcagagcaaggagtg
cctgtgccgtacagagccacgaccagcacaatcccagaagctccagttgctcagggggct
acagccgagatttttgatgactcctgctgcaacggcaccctacgcaagccagtggcaccc
cacgttccagaggatagcagcacccagaggtacagcgccgaccccacggtgtttgcccca
gaacggagcccacgaggagagctggatgaagaaggttacatgacccctatgcgagataaa
cctaaacaagaatacctgaaccctgtggaagaaaacccttttgtttctcggagaaaaaat
ggagaccttcaagctttggataatcccgaatatcacaatgcttccaacggtccacccaag
gcagaggatgagtatgtgaatgagccactgtacctcaacacctttgccaacgcgttggga
aatgccgggtatctgaagaacaatgtactgtctgtgccagaaaaggccaagaaagcattc
gacaaccctgactactggaatcacagcctgccaccccggagcacccttcagcacccagac
tacctgcaggagtacagcacaaaatatttttataaacaaaatggacggatccggcctatt
gtggcagagaatcctgaatacctctctgagttctcgctgaagccaggcaccgtgctgcct
cctccaccctacagacaccgaaacactgtggtgtaa
DBGET
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