Panthera tigris altaica (Amur tiger): 102963520
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Entry
102963520 CDS
T02988
Symbol
ROCK1
Name
(RefSeq) Rho associated coiled-coil containing protein kinase 1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.1
]
Organism
ptg
Panthera tigris altaica (Amur tiger)
Pathway
ptg04022
cGMP-PKG signaling pathway
ptg04024
cAMP signaling pathway
ptg04062
Chemokine signaling pathway
ptg04071
Sphingolipid signaling pathway
ptg04270
Vascular smooth muscle contraction
ptg04350
TGF-beta signaling pathway
ptg04360
Axon guidance
ptg04510
Focal adhesion
ptg04520
Adherens junction
ptg04530
Tight junction
ptg04611
Platelet activation
ptg04670
Leukocyte transendothelial migration
ptg04810
Regulation of actin cytoskeleton
ptg04921
Oxytocin signaling pathway
ptg05135
Yersinia infection
ptg05163
Human cytomegalovirus infection
ptg05200
Pathways in cancer
ptg05205
Proteoglycans in cancer
ptg05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ptg00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
102963520 (ROCK1)
04071 Sphingolipid signaling pathway
102963520 (ROCK1)
04024 cAMP signaling pathway
102963520 (ROCK1)
04022 cGMP-PKG signaling pathway
102963520 (ROCK1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
102963520 (ROCK1)
04520 Adherens junction
102963520 (ROCK1)
04530 Tight junction
102963520 (ROCK1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
102963520 (ROCK1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
102963520 (ROCK1)
04670 Leukocyte transendothelial migration
102963520 (ROCK1)
04062 Chemokine signaling pathway
102963520 (ROCK1)
09152 Endocrine system
04921 Oxytocin signaling pathway
102963520 (ROCK1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
102963520 (ROCK1)
09158 Development and regeneration
04360 Axon guidance
102963520 (ROCK1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
102963520 (ROCK1)
05206 MicroRNAs in cancer
102963520 (ROCK1)
05205 Proteoglycans in cancer
102963520 (ROCK1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
102963520 (ROCK1)
09171 Infectious disease: bacterial
05135 Yersinia infection
102963520 (ROCK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptg01001
]
102963520 (ROCK1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ptg03036
]
102963520 (ROCK1)
Enzymes [BR:
ptg01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
102963520 (ROCK1)
Protein kinases [BR:
ptg01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
102963520 (ROCK1)
Chromosome and associated proteins [BR:
ptg03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
102963520 (ROCK1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
DUF1192
APH
Motif
Other DBs
NCBI-GeneID:
102963520
NCBI-ProteinID:
XP_007076007
UniProt:
A0A8C9KB13
LinkDB
All DBs
Position
Un
AA seq
1355 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLSSANPNDNRSSPNV
DKSLQENLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLEST
VSQIEKEKMLLQHRINEYQRKVEQENEKRRNVENEVSTLKDQLEDLKKVSQNSQLANEKL
TQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKTQMD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLSLQLEQES
NKRVLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLTTQLDLAETKAE
SEQLARGLLEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSMLTKDLELLRKENE
ELTDKMRRKEEEYKLKKEEEINNLKATYEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSIPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSNPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDVEMEPVQQAEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSAKTSS
NT seq
4068 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcggattgtttgctggatggattggatgctttggtatatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttttaagcagatataaa
gacacaataaataaaattagagatttacgaatgaaagctgaagattatgaagtagtgaag
gtgattggtagaggtgcatttggagaagttcaattggtaaggcataaatccaccaggaag
gtatatgctatgaagcttcttagtaaatttgaaatgattaagagatctgattctgctttt
ttctgggaagaaagagacatcatggcttttgctaacagtccttgggtcgttcagcttttt
tatgcattccaagatgatcgttatctctacatggtgatggagtacatgcctggtggagat
cttgtaaacttaatgagcaactatgatgtgcctgaaaaatgggcacgattctacactgca
gaagtagttcttgcattggatgcaatccattccatgggtttcattcatagagatgtgaag
cctgataacatgctgctggataaatctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgatacagcagttggaacacccgattac
atttcccctgaagtattaaaatctcaaggtggtgatggttattatggacgagaatgtgac
tggtggtcagttggggtatttttatatgaaatgcttgtaggtgatacacctttttatgca
gattctctggttggaacttatagtaagattatgaaccataaaaattcacttactttccct
gatgataatgatatatcaaaagaagcaaaaaatcttatttgtgccttccttactgacaga
gaggtgagattaggacgaaatggtgtggaagaaatcaaacgacatcttttcttcaaaaat
gatcagtgggcttgggaaacactcagagacactgtagcgccagttgtacctgatttaagt
agcgacattgatacaagtaattttgatgacttggaagaagataaaggagatgaagaaaca
ttccctatacctaaagcttttgttggcaatcagttaccttttgtaggatttacgtattat
agcaatcgtagatacttatcttcagcaaatcctaatgataaccgaagtagccccaatgtg
gataaaagcttgcaggaaaatttgcaaaaaacaatttacaagctggaagaacaactgcat
aatgaaatgcaattaaaagatgaaatggagcagaagtgcagaacttcaaacataaaacta
gacaagataatgaaagaattggatgaagagggaaatcaaagaagaaacctagagtctaca
gtgtctcagattgagaaagagaaaatgttgctacagcatagaattaatgagtaccaaaga
aaagtagaacaggaaaatgagaagaggagaaatgtagaaaatgaagtttctacattaaag
gatcagttagaagacttaaagaaagtaagtcagaattcacagcttgctaatgagaagctg
acacagttacaaaagcagctagaagaagccaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcacacagagatgagtaagtcaattagtcagctagagtcc
ttaaacagagaattgcaggagagaaatagaattttagagaattccaagacacaaatggac
aaggactattaccagctgcaagctgtgttagaagctgaacgaagagacagaggtcatgat
tctgagatgattggagaccttcaagctcgaattacatctttacaagaagaggtaaagcat
ctcaagcataatcttgaaagagtggaaggagaaagaaaagaagctcaagacatgcttaat
cactcagaaaaggaaaagaataatttagagatagatttaaactataagcttaaatcatta
caacaaaggttagaacaagaggtaaatgaacataaagtaaccaaagctcgtttaactgac
aaacatcagtctattgaagaggcaaagtctgttgcaatgtgtgaaatggaaaagaagctg
aaggaagagagagaagctcgagagaaggctgaaaatagagttgttcagattgagaaacag
tgttcaatgctagatgttgatctgaaacaatctcagcagaagcttgagcatttgactgaa
aataaagaaaggatggaggatgaagttaagaatctatccctgcaactggagcaggaatca
aataagcgagtattgttacagaatgaattgaagactcaagcgtttgaagcggacaattta
aaaggtctagaaaagcagatgaaacaggaaataaatactttattggaagcaaagagatta
ttagaatttgagttagctcagcttacaaaacagtatagaggaaatgaaggacagatgcgg
gagctacaagatcagcttgaagcagagcaatatttttcgacactttataaaacccaagta
aaggaacttaaggaagaaattgaagaaaaaaacagagaaaatttaaagaaaatacaggaa
ctacaaaatgaaaaagaaactcttactactcagttggatctagcagaaacaaaagccgag
tctgagcagttggctcgagggcttctggaagaacagtattttgaattgacccaagaaagc
aagaaagctgcctcaagaaatagacaggagattacagataaagatcacactgttagtcgg
cttgaagaaacaaacagcatgctaaccaaagatcttgagttattaagaaaagaaaatgaa
gagctaactgataaaatgaggaggaaagaggaagaatataaactgaagaaagaggaagag
atcaataatcttaaggctacctatgaaaagaatatcagtacagaaagaacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcggaaagattttaaaattgatagaaag
aaagctaatacacaggatttgagaaagaaagaaaaggaaaatcgaaagcttcaactggaa
ctcaaccaagaaagagagaaattcaaccagatggtggtgaaacatcagaaggaactgaat
gacatgcaagcgcaattggtagaagaatgtacacataggaatgagcttcagatgcaattg
gctagcaaagagagtgatattgagcaattgcgtgctaaacttttggacctttcggattct
acaagtgttgctagttttcctagtgctgatgaaactgatggaaaccttccagagtcaaga
attgaaggctggctttcaataccaaacagaggaaatatcaaacgatatggctggaagaaa
cagtatgttgtagtaagcagcaaaaaaattttgttctataatgatgagcaagataaggaa
caatccaatccatccatggtattggacatagataaattgtttcatgttcgacctgtaacc
caaggagatgtttacagagctgaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatgtagagatggaaccagtacagcaagctgaaaag
actaattttcaaaaccacaaaggccatgagttcattcctacactctaccactttcccgcc
aactgtgaggcctgtgccaaacctctctggcatgtttttaagccacctcctgccctagaa
tgtcgaagatgccatgttaagtgccacagagatcacttagataagaaagaggacttaatt
tctccatgtaaagtcagttatgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaaatgggtaacacatttggtgaagaagatccctaagaatcca
ccatctggttttgttcgtgcatcccctcgaacactttctacaagatccactgcaaatcag
tctttccgaaaagtggtcaaaaatacatctgcaaaaactagcagttaa
DBGET
integrated database retrieval system
