KEGG   Pan troglodytes (chimpanzee): 471723
Entry
471723            CDS       T01005                                 
Symbol
IL12B
Name
(RefSeq) interleukin-12 subunit beta
  KO
K05425  interleukin 12B
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04060  Cytokine-cytokine receptor interaction
ptr04620  Toll-like receptor signaling pathway
ptr04622  RIG-I-like receptor signaling pathway
ptr04625  C-type lectin receptor signaling pathway
ptr04630  JAK-STAT signaling pathway
ptr04658  Th1 and Th2 cell differentiation
ptr04936  Alcoholic liver disease
ptr04940  Type I diabetes mellitus
ptr05133  Pertussis
ptr05134  Legionellosis
ptr05140  Leishmaniasis
ptr05142  Chagas disease
ptr05143  African trypanosomiasis
ptr05145  Toxoplasmosis
ptr05146  Amoebiasis
ptr05152  Tuberculosis
ptr05162  Measles
ptr05164  Influenza A
ptr05168  Herpes simplex virus 1 infection
ptr05171  Coronavirus disease - COVID-19
ptr05200  Pathways in cancer
ptr05205  Proteoglycans in cancer
ptr05321  Inflammatory bowel disease
ptr05330  Allograft rejection
ptr05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    471723 (IL12B)
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    471723 (IL12B)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    471723 (IL12B)
   04622 RIG-I-like receptor signaling pathway
    471723 (IL12B)
   04625 C-type lectin receptor signaling pathway
    471723 (IL12B)
   04658 Th1 and Th2 cell differentiation
    471723 (IL12B)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    471723 (IL12B)
   05205 Proteoglycans in cancer
    471723 (IL12B)
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    471723 (IL12B)
   05164 Influenza A
    471723 (IL12B)
   05162 Measles
    471723 (IL12B)
   05168 Herpes simplex virus 1 infection
    471723 (IL12B)
  09171 Infectious disease: bacterial
   05133 Pertussis
    471723 (IL12B)
   05134 Legionellosis
    471723 (IL12B)
   05152 Tuberculosis
    471723 (IL12B)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    471723 (IL12B)
   05145 Toxoplasmosis
    471723 (IL12B)
   05140 Leishmaniasis
    471723 (IL12B)
   05142 Chagas disease
    471723 (IL12B)
   05143 African trypanosomiasis
    471723 (IL12B)
  09163 Immune disease
   05321 Inflammatory bowel disease
    471723 (IL12B)
   05330 Allograft rejection
    471723 (IL12B)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    471723 (IL12B)
  09167 Endocrine and metabolic disease
   04940 Type I diabetes mellitus
    471723 (IL12B)
   04936 Alcoholic liver disease
    471723 (IL12B)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ptr04052]
    471723 (IL12B)
   00536 Glycosaminoglycan binding proteins [BR:ptr00536]
    471723 (IL12B)
Cytokines and neuropeptides [BR:ptr04052]
 Cytokines
  Interleukins
   471723 (IL12B)
Glycosaminoglycan binding proteins [BR:ptr00536]
 Heparan sulfate / Heparin
  Cytokines
   471723 (IL12B)
SSDB
Motif
Pfam: IL12p40_C Ig_3 Ig_5 Ig_4 Ig_2 fn3 Ig_RIMBP2 I-set ig
Other DBs
NCBI-GeneID: 471723
NCBI-ProteinID: XP_527101
Ensembl: ENSPTRG00000017481
VGNC: 4041
UniProt: A0A6D2W675 H2QRX3
LinkDB
Position
4:complement(157008093..157024690)
AA seq 328 aa
MCHQQLVISWFSLVFLASPLVAIWELKKDVYVVELDWYPDAPGEMVVLTCDTPEEDGITW
TSDQSSEVLGSGKTLTIQVKEFGDAGQYTCHKGGEVLSHSLLLLHKKEDGIWSTDILKDQ
KEPKTKTFLRCEAKNYSGRFTCWWLTTISTDLTFSVKSSRGSSDPQGVTCGAATLSAERV
RGDNKEYEYSVECQEDSACPAAEESLPIEVMVDAVHKLKYENYTSSFFIRDIIKPDPPKN
LQLKPLKNSRQVEVSWEYPDTWSTPHSYFSLTFCVQVQGKSKREKKDRVFTDKTSATVIC
RKNASISVRAQDRYYSSSWSEWASVPCS
NT seq 987 nt   +upstreamnt  +downstreamnt
atgtgtcaccagcagttggtcatctcttggttttccctggtttttctggcatctcccctc
gtggccatatgggaactgaagaaagatgtttatgtcgtagaattggattggtatccggat
gcccctggagaaatggtggtcctcacctgtgacacccctgaagaagatggtatcacctgg
acctcggaccagagcagtgaggtcttaggctctggcaaaaccctgaccatccaagtcaaa
gagtttggagatgctggccagtacacctgtcacaaaggaggcgaggttctaagccattca
ctcctgctgcttcacaaaaaggaagatggaatttggtccactgatattttaaaggaccag
aaagaacccaaaactaagacctttctaagatgcgaggccaagaattattcaggacgtttc
acctgctggtggctgacgacaatcagtactgatttgacattcagtgtcaaaagcagcaga
ggctcttctgacccccaaggggtgacgtgcggagctgctacactctctgcagagagggtc
agaggggacaacaaggagtatgagtactcagtggagtgccaggaggacagtgcctgccca
gctgctgaggagagtctgcccattgaggtcatggtggatgctgttcacaagctcaagtat
gaaaactacaccagcagcttcttcatcagggacatcatcaaacctgacccacccaagaac
ttgcagctgaagccattaaagaattctcggcaggtggaggtcagctgggagtaccctgac
acctggagtactccacattcctacttctccctgacattctgcgttcaggtccagggcaag
agcaagagagaaaagaaagatagagtcttcacggacaagacctcagccacggtcatctgc
cgcaaaaatgccagcattagcgtgcgggcccaggaccgctactatagctcatcttggagc
gaatgggcatctgtgccctgcagttag

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