Pan troglodytes (chimpanzee): 745437
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Entry
745437 CDS
T01005
Symbol
EZH2
Name
(RefSeq) histone-lysine N-methyltransferase EZH2 isoform X1
KO
K11430
[histone H3]-lysine27 N-trimethyltransferase EZH2 [EC:
2.1.1.356
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr00310
Lysine degradation
ptr01100
Metabolic pathways
ptr03083
Polycomb repressive complex
ptr05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
745437 (EZH2)
09120 Genetic Information Processing
09126 Chromosome
03083 Polycomb repressive complex
745437 (EZH2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
745437 (EZH2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
ptr03036
]
745437 (EZH2)
Enzymes [BR:
ptr01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.356 [histone H3]-lysine27 N-trimethyltransferase
745437 (EZH2)
Chromosome and associated proteins [BR:
ptr03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
745437 (EZH2)
Polycomb repressive complex (PRC) and associated proteins
PRC2.1
745437 (EZH2)
PRC2.2
745437 (EZH2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Ezh2_MCSS
PRC2_HTH_1
SET
EZH2_WD-Binding
preSET_CXC
Motif
Other DBs
NCBI-GeneID:
745437
NCBI-ProteinID:
XP_009452720
Ensembl:
ENSPTRG00000019837
VGNC:
4343
LinkDB
All DBs
Position
7:complement(145521954..145598448)
Genome browser
AA seq
759 aa
AA seq
DB search
MIYFIRIIMGQTGKKSEKGPVCWRKRVKSEYMRLRQLKRFRRADEVKSMFSSNRQKILER
TEILNQEWKQRRIQPVHILTSVSSLRGTRECSVTSDLDFPTQVIPLKTLNAVASVPIMYS
WSPLQQNFMVEDETVLHNIPYMGDEVLDQDGTFIEELIKNYDGKVHGDRECGFINDEIFV
ELVNALGQYNDDDDDDDGDDPEEREEKQKDLEDHRDDKESRPPRKFPSDKIFEAISSMFP
DKGTAEELKEKYKELTEQQLPGALPPECTPNIDGPNAKSVQREQSLHSFHTLFCRRCFKY
DCFLHRKCNYSFHATPNTYKRKNTETALDNKPCGPQCYQHLEGAKEFAAALTAERIKTPP
KRPGGRRRGRLPNNSSRPSTPTINVLESKDTDSDREAGTETGGENNDKEEEEKKDETSSS
SEANSRCQTPIKMKPNIEPPENVEWSGAEASMFRVLIGTYYDNFCAIARLIGTKTCRQVY
EFRVKESSIIAPAPAEDVDTPPRKKKRKHRLWAAHCRKIQLKKDGSSNHVYNYQPCDHPR
QPCDSSCPCVIAQNFCEKFCQCSSECQNRFPGCRCKAQCNTKQCPCYLAVRECDPDLCLT
CGAADHWDSKNVSCKNCSIQRGSKKHLLLAPSDVAGWGIFIKDPVQKNEFISEYCGEIIS
QDEADRRGKVYDKYMCSFLFNLNNDFVVDATRKGNKIRFANHSVNPNCYAKVMMVNGDHR
IGIFAKRAIQTGEELFFDYRYSQADALKYVGIEREMEIP
NT seq
2280 nt
NT seq
+upstream
nt +downstream
nt
atgatatactttattagaataatcatgggccagactgggaagaaatctgagaagggacca
gtttgttggcggaagcgtgtaaaatcagagtacatgcgactgagacagctcaagaggttc
agacgagctgatgaagtaaagagtatgtttagttccaatcgtcagaaaattttggaaaga
acggaaatcttaaaccaagaatggaaacagcgaaggatacagcctgtgcacatcctgact
tctgtgagctcattgcgcgggactagggagtgttcggtgaccagtgacttggattttcca
acacaagtcatcccattaaagactctgaatgcagttgcttcagtacccataatgtattct
tggtctcccctacagcagaattttatggtggaagatgaaactgttttacataacattcct
tatatgggagatgaagttttagaccaggatggtactttcattgaagaactaataaaaaat
tatgatgggaaagtacacggggatagagaatgtgggtttataaatgatgaaatttttgtg
gagttggtgaatgcccttggtcaatataatgatgatgacgatgatgatgatggagacgat
cctgaagaaagagaagaaaagcagaaagatctggaggatcaccgagatgataaagaaagc
cgcccacctcggaaatttccttctgataaaatttttgaagccatttcctcaatgtttcca
gataagggcacagcagaagaactaaaggaaaaatataaagaactcaccgaacagcagctc
ccaggcgcacttcctcctgaatgtacccccaacatagatggaccaaacgctaaatctgtt
cagagagagcaaagcttacactcctttcatacgcttttctgtaggcgatgttttaaatat
gactgcttcctacatcgtaagtgcaattattcttttcatgcaacacccaacacttataag
cggaagaacacagaaacagctctagacaacaaaccttgtggaccacagtgttaccagcat
ttggagggagcaaaggagttcgctgctgctctcaccgctgagcggataaagaccccacca
aaacgtccaggaggccgcagaagaggacggcttcccaataacagtagcaggcccagcacc
cccaccattaatgtgctggaatcaaaggatacagacagtgatagggaagcagggactgaa
acggggggagagaacaatgataaagaagaagaagagaagaaagatgaaacttcgagctcc
tctgaagcaaattctcggtgtcaaacaccaataaagatgaagccaaatattgaacctcct
gagaatgtggagtggagtggtgctgaagcctcaatgtttagagtcctcattggcacttac
tatgacaatttctgtgccattgctaggttaattgggaccaaaacatgtagacaggtgtat
gagtttagagtcaaagaatctagcatcatagctccagctcccgctgaggatgtggatact
cctccaaggaaaaagaagaggaaacaccggttgtgggctgcacactgcagaaagatacag
ctgaaaaaggacggctcctctaaccatgtttacaactatcaaccctgtgatcatccacgg
cagccttgtgacagttcgtgcccttgtgtgatagcacaaaatttttgtgaaaagttttgt
caatgtagttcagagtgtcaaaaccgctttccgggatgccgctgcaaagcacagtgcaac
accaagcagtgcccgtgctacctggctgtccgagagtgtgaccctgacctctgtcttact
tgtggagccgctgaccattgggacagtaaaaatgtgtcctgcaagaactgcagtattcag
cggggctccaaaaagcatctattgctggcaccatctgacgtggcaggctgggggattttt
atcaaagatcctgtgcagaaaaatgaattcatctcagaatactgtggagagattatttct
caagatgaagctgacagaagagggaaagtgtatgataaatacatgtgcagctttctgttc
aacttgaacaatgattttgtggtggatgcaacccgcaagggtaacaaaattcgttttgca
aatcattcggtaaatccaaactgctatgcaaaagttatgatggttaacggtgatcacagg
ataggtatttttgccaagagagccatccagactggcgaagagctgttttttgattacaga
tacagccaggctgatgccctgaagtatgtcggcatcgaaagagaaatggaaatcccttga
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