KEGG   Panthera uncia (snow leopard): 125918704
Entry
125918704         CDS       T08832                                 
Name
(RefSeq) serine/threonine-protein kinase WNK1 isoform X1
  KO
K08867  WNK lysine deficient protein kinase [EC:2.7.11.1]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc04928  Parathyroid hormone synthesis, secretion and action
Brite
KEGG Orthology (KO) [BR:puc00001]
 09150 Organismal Systems
  09152 Endocrine system
   04928 Parathyroid hormone synthesis, secretion and action
    125918704
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:puc01001]
    125918704
   01009 Protein phosphatases and associated proteins [BR:puc01009]
    125918704
Enzymes [BR:puc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     125918704
Protein kinases [BR:puc01001]
 Serine/threonine kinases: Other
  Wnk family
   125918704
Protein phosphatases and associated proteins [BR:puc01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     125918704
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr CCTL2_WNK OSR1_C
Other DBs
NCBI-GeneID: 125918704
NCBI-ProteinID: XP_049480799
LinkDB
Position
B4:complement(36037239..36199611)
AA seq 2794 aa
MSGGASEKQSSTPSSLFLSPPAPSPKNGSSSDSSVGEKLGSAGPDAGTGRTEEYRRRRHT
MDKDSRGAAATTTTTEHRFFRRSVICDSNATALELPGLPLSLPQPAVSTAAPQSTPPEPH
REETLTATAAAQVAQLPPAAAAPGEPAGAGAVAATAPSSTGRDRQVSQPNHVGSKEEPPS
ARSGSGGGGSAKEPQEERSQQQDDIEELETKAVGMSNDGRFLKFDIEIGRGSFKTVYKGL
DTETTVEVAWCELQDRKLTKSERQRFKEEAEMLKGLQHPNIVRFYDSWESTVKGKKCIVL
VTELMTSGTLKTYLKRFKVMKIKVLRSWCRQILKGLQFLHTRTPPIIHRDLKCDNIFITG
PTGSVKIGDLGLATLKRASFAKSVIGTPEFMAPEMYEEKYDESVDVYAFGMCMLEMATSE
YPYSECQNAAQIYRRVTSGVKPASFDKVAIPEVKEIIEGCIRQNKDERYSIKDLLNHAFF
QEETGVRVELAEEDDGEKIAIKLWLRIEDIKKLKGKYKDNEAIEFSFDLERDVPEDVAQE
MVESGYVCEGDHKTMAKAIKDRVSLIKRKREQRQLVREEQEKRKQEEINQKHQVEQQSST
SQAGVKQIPSASTGMPPASTTSASVSTQVEPEEPEADQHQQLQYQQTSISVLSDGTVDSG
QGSSVFTESRVSSQQTVSYGSQHEQAHSTGTIPGHTASVVQAQSQPHGVYPSSSMPQSMA
HPCGGTPTYPESQIFFPTIHERPVSFSPPPTCPPKVAISQRRKSTSFLEAQTRHFQPLLR
TVGQNLLPPGGSPTNWTPEAVVMLGTTASRITGEPSEIQVHPMFEPTQVHGDYRPGLVLP
EEAHYFIPQEPVYLAYQAQVTEQYEGIPYNSPVLSSPMKQIPEQKPVPGGPTSSSVFEFP
SGQAFLVGHLQNLRLDSGLSPGSPLSSISAPISTDATRLKFHPVFVPHSAPAVLTHNNES
RSNCVFEFHVHTPSSSSGEGGGVLPQRVYRNRQVAVDFNQEEPPPQSVGLHGRLQPVTEE
QRNYHAPELTVSVVEPIGQNWPIGSPEYSSDSSQITSSDPSDFQSPPPTGGAAAPFGSDV
SLPFIHLPQTVLQESPLFFCFPQGTTSQQVLSASFSSGGSALHPQAQGQSQGQPSSSSLT
GVPSSLPIQHSQQQQGVQQTAPPQQTVQYSLPQTSTSSEATTAQPVSQSQTPQVLPQVSS
GKQLPVSQPVPAIQGEPQIPVATQPSVVPVHSGAHFLPLGQPLSTSLHPQYPVSQIPIST
PHVSAAQTGFSSLPVTMAAGVNQPLLTLASSATAAAIPGGPTAVPSQLPTLLQPVTQLPS
QVHPQLLQPAVQSMGIPANLGQAAEVPLPSGDVLYQGFPPRLPPQYPGDSNIAPTSSVAS
ICIPSTVLSPPMPTEALATPGYFPTVVQPFVESNLLVPVGSIGGQVQVSQPAVSLAQQAP
TTSSQQAALESTQGVSQVAPPEPLPVAQAQPTTLVSSIDSAHSDVASGMSDGNENVPSSS
GRHEGRTTKRHYRKSVRSRSRHEKSSRPKLRILNVSNKGDRVVECQLETHNRKMVTFKFD
LDGDNPEEIATIMVNNDFILAIERESFVDQVREIIEKADEMLSEDVSVEPEGDQGLESLQ
GKDDYGFAGSQKLEGEFKQPIPASSMPQQIGIPTSSLTQVVHSAGRRFIVSPVPESRLRE
SKLFTGEISDTVAASTSHGAGMNLSHSASSLSLQQAFSELRHAQMTEGPNTAPPNFSHTG
PTFPVVPPSMSSIAAVPTTAAATPSISAPATSSPLNDMSTSVIQSEIPVPTEKGIGGVAT
CTGVIPSSGLPVPPISESPVFSTVVSSITIPTVVSISTTSQPVQASISGSVVSSIGTLPS
IPVSTLASAAGSAAVSGAKPPPVVSQQATGSTSGVATLTSIAATTPFPSIASQLPLQLSS
STSAPTLAETVVVSAHSLDKTSHSSTTGLALSLSASSSSSPGAGLSSSVSQPGGVHPLVT
PSAIASTPVLSQAGGPTSTPLLPQVPSIPPLVQPVASVPAVQQTLIHSQPQPALLPNQPH
THCPEIDADSQPKAPGIDDIKTLEEKLRSLFSEHSSSGAQHASVSLETSLVVETTVAPGI
PTTAVAPSKLMTSTTSTCLPPTSLPLGTTGLSVIPVVTPGQVSTPVSYVSAPVTTTSGVK
AGTAPSKPPLTKAPVLPVGTELPAGTPPSEQLPPFPGPSLTQSQQPLEDLDAQLRRTLSP
ETVVVTSTVGPVSVVAPAAVTEAGTPPQKDVSQITEGPVLGTSSGTGVFKMGRFQVSVAM
DDVQKEGKNKSEDAKSVHFESSTSESSVLSSSSPESTLVKTEPNGIRSISSDMPDSAHKT
PALGAKSETGQPTKVGRFQVTTTTNKVGRFSVSRTEDKIAEAKKEGPMASPPFMDLEQAV
LPAVIPKKEKPELSEPSHLNGPSSDLEAAFLSRDVDDGSGSPHSPHQLSSKSLPIQNLSQ
SLSNSFNSSYMSSDNESDIEDEDLKLELRRLREKHLKEIQDLQSRQKHEIESLYTKLGKV
PPAVIIPPAAPLAGRRRRPTKSKGSKSSRSSSLGNKSPQLSGNLSGQSATSVLHPQQTLH
PPGNIPETGQNQLLQPLKPSPSSDNLYSAFTSDGAISVPSLSAPGQGTSSTNTVGGTVNS
QAAQAQPPAMTSSRKGTFTDDLHKLVDNWARDAMNLSGRRGSKGHMNYEGPGMARKFSAP
GQLCISMTSNLGGSAPISAASATSLGHFTKSMCPPQQYGFPAPPFGTQWSGTGGPTPQPL
GQFQPVGTASLQNFNISNLQKSISNPPGSNLRTT
NT seq 8385 nt   +upstreamnt  +downstreamnt
atgtctggcggcgcctcagagaagcagagcagcactccgagctccttgttcctctcgccg
ccggcgccttcccccaagaatggctccagctccgattcctcggtgggggagaaactgggc
agcgcggggcccgacgccggaactggccggacagaggagtaccggcgtcgccgccacact
atggacaaggacagccgtggcgcggccgccaccactaccaccactgagcaccgcttcttc
cgccgcagcgtcatctgcgactccaacgccactgcgctggaactgcccggccttcccctt
tctctcccccagcccgccgtctccacggcggctccgcagagcaccccgccggagccccac
cgcgaggagaccttgaccgccaccgccgctgcccaggtagcccagctgcctcccgccgct
gccgcccccggggagccagccggcgcgggcgctgtagccgcgaccgcccccagcagtacc
ggcagagaccgccaagtttcccagcccaaccatgtggggagcaaagaggagcctccgtcg
gccagaagtggcagcggcggcggcggcagcgccaaggaaccacaggaggaacggagccag
caacaggatgacatcgaagagctggagaccaaggccgtgggaatgtccaacgatggccgc
tttctcaaattcgacatcgagattggccgaggctcctttaagaccgtctacaaaggtctc
gacactgaaactactgtggaggtcgcctggtgtgaactgcaggatcgaaaattaacaaag
tctgagaggcagagatttaaagaagaggcagaaatgttaaagggccttcagcatcccaat
attgttcgattctatgattcctgggagtccacagtaaaagggaagaagtgcattgttttg
gtgactgaactaatgacatctggaacacttaaaacgtatctgaaaaggtttaaggtgatg
aagattaaagttctaagaagctggtgccgtcagatcctaaaaggacttcagtttcttcat
acccgaactccgcctattattcaccgagatcttaagtgtgacaacatctttatcactggc
cctacaggctcagtcaagattggagacctaggtctggcaaccctgaagcgggcttctttt
gccaagagtgtgataggtaccccagagttcatggcccctgagatgtatgaggaaaaatat
gatgaatctgttgatgtttatgcttttgggatgtgcatgcttgagatggccacatctgaa
tacccttactcagagtgccaaaatgctgcgcagatctaccgtcgagtgaccagtggagtg
aagcctgccagttttgacaaagtagcaattcctgaagtgaaggaaattattgaaggatgc
ataaggcaaaacaaagatgaaagatattctatcaaagaccttttgaaccatgccttcttc
caggaggaaacaggggtacgggtagaattagcagaagaagatgatggagaaaagatagcc
attaaattatggctacgtattgaagatattaagaaactaaagggaaaatacaaagacaat
gaagctattgagttttcctttgacttggaaagagatgtgccagaagacgttgctcaagaa
atggtagagtctgggtatgtctgtgaaggtgatcacaagaccatggcaaaagccatcaaa
gatagagtatcattaattaagagaaaacgagaacaacggcagttggtacgggaggaacaa
gaaaaaagaaagcaggaagagatcaatcagaaacaccaggtagaacaacaatcaagtact
tcccaggcaggagtcaaacagatcccatctgctagtactggcatgcctcctgcttctacc
acatcagcttcagtttctacacaagtagaacctgaagaacctgaggcagatcaacatcaa
caactacagtaccaacaaactagtatatctgtgttatctgacgggacggttgacagtggt
caaggatcttctgtcttcacagaatctcgagtgagcagccaacagacagtttcatatggg
tcccaacatgaacaggcacattctactggcacaatcccagggcatacagcttctgttgtc
caagcacaatctcagcctcatggggtatatccatcctcaagtatgcctcagtccatggcg
catccgtgtggggggaccccaacatacccagaatcacagatatttttcccaactattcat
gaacgtccagtttctttttcaccacctcccacctgtccaccgaaggtggccatttcccag
cggcgtaagagcacctccttcttggaagcccaaactcgccacttccaacccctgctgagg
actgttggccaaaatcttcttccacctggtggcagcccaactaactggacaccagaggcc
gtagttatgttgggcactacagccagtagaataactggagagccaagtgagatacaggtc
catcctatgtttgaaccaactcaagttcacggtgactatagacctggactagtacttcca
gaagaagctcactattttattcctcaggaaccagtgtatctagcttaccaggcccaggtg
acagaacagtatgagggtattccatacaactcaccagtactgtcaagtcctatgaaacag
atacctgaacagaagccagtaccagggggccctacctcaagttctgtctttgaatttcca
tctggacaggctttcctggtaggacaccttcagaatttaagattagattctggattgagt
ccaggatctcccctctctagtatttctgcacctatcagtactgatgctacacgtttgaaa
tttcaccctgtctttgttcctcattctgcgcccgctgtgttaactcataacaatgagagc
agaagcaattgtgtatttgagtttcatgttcacactccaagctcctcttcgggagaagga
ggaggagtcttgcctcagcgtgtttaccgaaatcgacaggttgcagtggacttcaatcag
gaagaaccacctcctcaatcagttggattacatggccgcctacagcctgtgactgaagaa
cagcgtaattaccatgccccagaattgaccgtttctgtggtagagcctatcggacagaac
tggccaataggaagcccagaatattccagtgattcctcacaaattacttcttcagacccc
agtgattttcaatcacctccccctacagggggagcagctgcaccttttggctctgacgtc
tcattaccctttatccatctgcctcagacagtgttacaagaatccccacttttcttctgt
ttcccccaaggaaccacatctcagcaggttttatctgcctcattttcttcaggaggatct
gcactccatccacaggcacaggggcaaagccagggtcaaccatcctcaagtagcctaaca
ggggttccatcttccctgcccatacaacattctcagcagcagcagggagtacagcagact
gcccctcctcaacagacagtgcagtattcacttccacagacatcaacctccagtgaggcc
actactgcacagccagtcagtcagtctcagactccacaggtcttgcctcaagtatcatct
ggaaaacagcttccagtttcccagccagtaccagctatccaaggcgaacctcagatccca
gttgcgacacaaccctcagttgttccagtccactctggtgctcatttcctccctctggga
cagccactctctacttccttacacccccagtatcctgtctctcaaattcccatatcaact
cctcatgtgtctgcggctcagacaggtttctcatcccttcccgttacaatggcagctggc
gttaatcagcctctgctcaccttggcctcatctgctacggcagctgcgatcccaggggga
ccaactgcggttcctagtcagcttccaacccttctgcagcctgtgactcagctgccaagt
caggttcacccacagctcctgcaaccagcagttcagtccatgggaataccagctaacctt
ggacaagctgctgaggttccacttccctctggagatgttctataccagggcttcccacct
cgactgccaccacaatacccaggagattcaaatattgctcccacttccagcgtggcttct
atttgcatcccttctacagtcctatcccctcccatgccgacagaagcactggctacaccg
ggttactttcctacagtggtgcagccttttgtggaatcaaaccttttggttcctgtgggc
agtataggaggacaggttcaagtgtctcagccagcagtgagtttagcacaacaagccccc
actacatcctcccagcaagcagctctggagagtactcagggagtctctcaagttgctcct
ccagagccacttccagtggcacaggcacaacctaccactttggtctcttctatagacagt
gcacattcagatgttgcttcaggaatgagtgatggcaatgagaatgtcccatcatccagt
ggaaggcatgaagggagaactacaaaacggcattatcgaaaatctgtaagaagtcgctct
cgtcatgaaaagtcctcacgtccaaaattgagaattttgaatgtttcaaataaaggggac
cgggtagtagaatgtcagttagagactcataatcggaaaatggttacattcaaattcgat
ttagatggtgacaatcctgaggagatagcaacaattatggtgaacaatgactttatctta
gcaatagagagagagtcctttgtggatcaagtacgagaaattattgaaaaagctgatgaa
atgctcagcgaggacgtcagtgtggaaccagagggtgaccagggattggagagtctacag
ggaaaggatgactatggctttgcaggttctcagaaattggaaggagaattcaaacaacca
attcctgcatcttctatgccacagcaaataggcattcctaccagttctttaactcaagtt
gttcattctgctggaagacggtttatagtgagtcctgtgccagaaagccgattacgagaa
tcaaaacttttcactggtgaaatatcagatacggttgctgcctcaacatcccatggcgct
ggaatgaacttgtctcattctgcttcatcccttagcctacaacaggcgttttctgaactc
agacatgcccaaatgacagaagggcccaatacagcacctcccaacttcagtcatacagga
ccaacatttccagtagtacctccttccatgagtagcattgctgcagtcccaaccacagca
gcagccacaccttcaatatcagcccctgcaactagcagccctcttaatgacatgtccaca
tcagtaattcagtctgagattccagtgcccactgaaaaagggattggtggagttgccacc
tgcacaggtgtgataccgtcaagtggtctccctgtacctcctatatctgaatcaccagta
ttttccactgtggtttcaagcattacaatacctacagttgtctcaatatcaacaacatcc
cagccagttcaggcttctatatctgggagtgttgtttctagcataggcactttgccatct
ataccagtttcaacgttagcctctgctgcgggcagtgctgctgtctcaggtgctaagcct
ccacctgtagtatctcaacaagcgacaggcagtacttctggggtagccacgttaacatcc
attgctgccaccactccattcccgagcatagcttcccagctgcctcttcagctgagcagc
agcacctctgctcctactctagctgaaacagtggtggttagtgcacactcactagataaa
acatctcatagcagtacaactggattggctttgtccctgtctgcatcatcatcttcctcc
cctggagcaggattatctagttctgtttctcagcctggtggggtgcatcctttggtcacc
ccatcagctatagcttctactcctgtcctttctcaagcaggaggacctacttctacacct
ttattaccccaagtacctagtatcccacctttggtacaacctgttgccagtgtgcctgct
gtgcagcagacactaattcatagtcagcctcaaccagctttacttcccaaccagccccac
actcactgtcctgaaatagatgctgactcacagcccaaggctcctggaattgatgacata
aagactctagaggaaaagctgcggtctctctttagtgaacacagctcatctggagcccaa
catgcatctgtctcactggagacatcactggtagtagagaccactgtcgcaccaggcatc
ccaaccactgctgttgcaccaagcaagctcatgacttctactacaagtacatgcttacca
ccaacaagtttgccattagggacaactggtttgtcagttataccagtggtcacacctgga
caagtttccaccccagtcagctatgtgtccgccccagtcaccactacgtcaggagtgaaa
gctggaactgctccatcaaagccacctttaactaaagctccagtgctgccagtgggtact
gaacttccagctggtactccacccagcgagcagctgccaccttttccaggaccttcacta
actcagtcccagcaacctctggaagatcttgatgctcaattgagaagaacacttagtcca
gagactgttgtggtgacatctacagttgggcctgtgtccgtggtggctccagcagcagtt
acagaagcaggaacaccgcctcagaaggatgtttctcaaatcacagaaggtcctgtcctg
ggaactagttcaggaactggtgtttttaagatgggacgattccaggtttcagttgcaatg
gatgatgtccaaaaagagggtaaaaataagtcagaagatgcaaagtctgttcattttgag
tctagcacttcagagtcctcagtactatcaagtagtagtccagaaagtaccctggtgaag
acagagcctaatgggatccgtagcatctcatcagatatgccagatagtgcccacaaaact
cctgccttgggagcaaagtcagaaactgggcagcctacaaaggtaggacgcttccaggtg
acaactacaacgaacaaagtaggtcgtttctctgtatcaagaactgaagacaagattgct
gaggcaaagaaagagggaccaatggcatctcctccttttatggatttggaacaagctgtt
ctccccgctgtaataccaaagaaagaaaagcctgaactgtcagagccttcacatctgaat
gggccatcttctgacctggaggccgccttcctaagcagggatgtggatgatggttcaggt
agtccacactccccccatcagctgagctcaaagagcctccctatccagaatctaagtcag
agccttagtaattcattcaactcctcttacatgagtagtgacaatgagtcagatattgaa
gatgaagatttaaaattagagctgcgaagactacgagaaaaacatcttaaagagattcaa
gacctgcagagtcgccagaagcatgaaattgaatctttatataccaaactgggcaaggtt
ccccctgctgtcattattcccccagctgcccctcttgcagggagaagaaggcgacccact
aaaagcaaaggcagcaaatctagtcgcagcagttccttggggaataaaagcccccagctt
tcaggtaacctgtctggtcagagtgccacttcagttttgcacccccagcagaccctccac
cctcctggcaacatcccagagactgggcagaatcagttgttacagccccttaagccatct
ccctccagtgacaacctctattcagccttcaccagtgatggtgccatttcagtaccaagc
ctttctgctccaggtcaagggaccagcagcacaaatactgtcgggggaacagtgaacagc
caagccgcccaagctcagcctcctgccatgacgtccagcaggaagggcacatttacagat
gatctgcacaagttggtagacaattgggctcgagatgccatgaatctttcaggcaggaga
ggaagcaaaggacacatgaattatgagggccctggaatggcaaggaagttctccgcacct
ggtcagctgtgcatctccatgacctcaaacctgggtggttctgcccccatctctgctgca
tcagctacctctctaggtcacttcaccaagtccatgtgccccccacagcagtacggtttt
ccagctcccccctttggcactcagtggagtgggacaggtggcccaacaccacagccactt
ggccagttccaacctgtgggaactgcctccttacagaatttcaacatcagcaatttgcag
aaatccatcagcaaccccccaggttccaacttgcggaccacttag

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