KEGG   Panthera uncia (snow leopard): 125937592
Entry
125937592         CDS       T08832                                 
Name
(RefSeq) CAD protein isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc00220  Arginine biosynthesis
puc00240  Pyrimidine metabolism
puc00250  Alanine, aspartate and glutamate metabolism
puc01100  Metabolic pathways
puc01240  Biosynthesis of cofactors
Module
puc_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:puc00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    125937592
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    125937592
   00220 Arginine biosynthesis
    125937592
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:puc01002]
    125937592
Enzymes [BR:puc01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     125937592
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     125937592
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     125937592
Peptidases and inhibitors [BR:puc01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   125937592
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   125937592
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase OTCace_N CPSase_sm_chain OTCace CPSase_L_D3 ATP-grasp Dala_Dala_lig_C MGS ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 GARS_A Peptidase_C26
Other DBs
NCBI-GeneID: 125937592
NCBI-ProteinID: XP_049508350
LinkDB
Position
A3
AA seq 2302 aa
MGRSCGASPLGPLCRLPVKWVSKLGPAADLIPLSAAPLCPTCPAQTRHFPACTPSLPPPF
GARVPTLAPFIPQGQGSLRWGIVIAQGSGGKGVLPKPQPCLFLAVFQTGMVGYPEALTDP
SYKAQILVLTYPLIGNYGIPADETDEFGLSKWFESSGIHVAGLVVGECCPTPSHWSATHT
LHQWLEQHGIPGLQGVDTRELTKKLREQGSLLGKLVQDGTEPSALPFLDPNARPLVPEVS
IKAPRVFNAGGTPRILALDCGLKYNQIRCLCQRGAEVTVVPWDHALDSQEYEGVFLSNGP
GDPASYPSVVSTLSRVLSEPDPRPVFGICLGHQLLALAIGAKTYKMRYGNRGHNQPCLLV
GSGRCFLTSQNHGFAVETDSLPAGWLPLFTNANDRSNEGIVHDSLPFFSVQFHPEHQAGP
SDMELLFDIFLETVKEATAGNPGGQTVRERLVECLCPPGIPTPGSGLPPPRKVLILGSGG
LSIGQAGEFDYSGSQAIKALKEENIQTLLINPNIATVQTSQGLADKVYFLPITPHYVTQV
IRNERPDGILLTFGGQTALNCGVELTKAGVLARYGVRVLGTPVETIELTEDRRAFASRMA
EIGEHVAPSEAANSLEQAQAAAERLGYPVLVRAAFALGGLGSGFASNREELSALVAPAFA
HTSQVLVDKSLKGWKEIEYEVVRDAYGNCVTVCNMENLDPLGIHTGESIVVAPSQTLNDR
EYQLLRQTAIKVTQHLGIVGECNVQYALNPESEQYYIIEVNARLSRSSALASKATGYPLA
YVAAKLALGIPLPELRNSVTGGTAAFEPSLDYCVVKIPRWDLSKFLRVSTKIGSCMKSVG
EVMGIGRSFEEAFQKALRMVDENCVGFDHTVKPVSDMELETPTDKRIFVVAAALWAGYSV
ERLYELTRIDRWFLHRMKRIIAHAQLLEQHRGQPLPPDLLHQAKRLGFSDKQIALAVLST
ELAVRKLRQELGICPAVKQIDTVAAEWPAQTNYLYLTYWGTTHDLTFRTPHVLVLGSGVY
RIGSSVEFDWCAVGCIRQLRKMGYKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIY
ELENPEGVILSMGGQLPNNMAMALHRQQCRVLGTSPEAIDSAENRFKFSRLLDTIGISQP
QWRELSDLESARQFCQTVGYPCVVRPSYVLSGAAMNVAYTDGDLERFLSSAAAVSKEHPV
VISKFIQEAKEIDVDAVARDGVVAAIAISEHVENAGVHSGDATLVTPPQDITAKTLERIK
AIVHAVGQELQVTGPFNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDLVALATRVIM
GEEVEPVGLMTGSGVVGVKVPQFSFSRLAGADVVLGVEMTSTGEVAGFGESRCEAYLKAM
LSTGFKIPKKNILLTIGSYKNKSELLPTVRLLESLGYSLYASLGTADFYTEHGVKVTAVD
WHFEEAVDGECPPQRSILEQLAENHFELVINLSMRGAGGRRLSSFVTKGYRTRRLAADFS
VPLIIDIKCTKLFVEALGQIGPAPPLKVHVDCMTSQKLVRLPGLIDIHVHLREPGGTHKE
DFASGTAAALAGGVTMVCAMPNTRPPIIDAPALALAQKLAEAGARCDFALFLGASSENAG
TLGAVAGSAAGLKLYLNETFSELRLDNVAQWMEHFETWPSHLPIVAHAERQSVAAILMVA
QLTQRSVHICHVARKEEILLIKAAKARGLPVTCEVAPHHLFLSRDDLERLGPGKGEVRPE
LGSRQDVEALWENMAVIDCFASDHAPHTLEEKCGPRPPPGFPGLETMLPLLLTAVSEGRL
TLDDLLQRLHHSPRRIFHLPPQEDTYVEVDLEHEWTIPSHMPFSKAHWTPFEGQKVKGTV
RRVVLRGEVAYIDGQVLVPPGYGQDVRKWPQGVVPQLAPPAPATSEITTTPERPRRAIPG
LPDGRFHLPPRIHRASDPGLPAEEPKEKSSRKAAEPELMGTLDGTCYPPPPVPRQASPQN
LGTPGLLHPQTSPLLHSLVGQHILSVQQFTKDQMSHLFNVAHTLRMMVQKERSLDILKGK
VMASMFYEVSTRTSSSFAAAMARLGGAVLSFSEATSSVQKGESLADSVQTMSCYADVVVL
RHPQPGAVELAAKHCRRPVINAGDGVGEHPTQALLDIFTIREELGTVNGMTITMVGDLKH
GRTVHSLACLLTQYRVSLRYVAPPSLRMPPNVRAFVAARGTKQEEFESIEEALPDTDVLY
MTRIQKERFDSSQEYEACFGQFILTPHIMTRAKKKMVVMHPMPRVNEISVEVDSDPRAAY
FRQAENGMYIRMALLATVLGRF
NT seq 6909 nt   +upstreamnt  +downstreamnt
atgggtcggtcctgcggggccagccctttggggccgctgtgtcgactgccggtgaagtgg
gtaagcaagctcgggccggctgccgacctcatcccactctctgctgcccctctctgccca
acctgccctgcccaaacccgccattttcccgcctgcacacccagcctcccacccccattt
ggtgcccgtgtccccaccctagccccttttatccctcaaggtcaaggcagcctccgctgg
ggcattgtcatcgctcagggcagtggtgggaagggtgtcctgcccaagccccagccctgc
ctctttcttgcagtgtttcaaaccggcatggtcggctaccccgaggcccttactgaccct
tcctacaaagcacaaatcttagtgctgacatatcctctgatcggcaactatggcatccct
gcagatgaaacggatgagttcggtctcagtaagtggtttgaatcctcagggatccatgtg
gcaggactggtggtgggagagtgctgccccacacccagccactggagcgccacccacacc
ctgcatcagtggctggaacagcatggcatacctggcctgcaaggagtggatactcgggag
ctgactaagaagttgagagaacaagggtctctgctgggaaagctggtccaagatggaaca
gagccttcagccctgccattcttggaccccaatgcccgccccctggtgccagaggtctcg
attaaggctccacgggtcttcaatgcagggggcacccctcggatccttgctttggattgt
ggtctcaagtacaatcagatccgatgtctgtgccagcgtggagctgaggtcactgtggta
ccgtgggaccatgcattagacagccaggagtatgagggtgtcttcctgagtaatggccct
ggtgaccccgcctcctatcccagtgtggtatccacactgagccgtgtcttatctgagcct
gatccccgacctgtcttcgggatctgtctgggacaccagctgttggccttagccattggg
gccaagacatacaagatgagatatgggaaccgaggccataatcagccatgcttgctagtg
ggctctgggcgctgctttctgacatcccagaatcatgggtttgctgtggaaacagactca
ctgccagccggctggcttcctctctttaccaacgccaatgatcgttccaatgaaggcatt
gtacatgacagcctgcccttcttcagtgtccagtttcacccagagcaccaagctggtcct
tcagatatggagctgctttttgatatctttctggaaactgtgaaagaagccacagctggg
aaccccgggggccagacagttcgagagcggctggttgagtgcctctgtccccctgggatt
cccaccccaggctctgggcttccaccaccacgaaaggttctgatcctgggctctgggggc
ctctccattggccaagctggagagtttgactactcaggctctcaggcgattaaggccctg
aaggaggaaaacatccagacgttgctgataaaccccaacattgccacagtgcagacttcc
caggggctggctgacaaagtctatttccttcccataacgcctcactatgtaacccaggtg
atccgtaatgagcgcccagatggcatcttactgacttttgggggccagacagctctgaat
tgtggtgtggagctaaccaaggctggagtgttagctcggtatggggtccgggtcctgggc
acacctgtggaaaccattgaactgactgaagatcggcgggcatttgcctccaggatggca
gagattggagagcatgtggcccccagtgaggcggcaaattctcttgaacaggcccaggca
gctgctgagcggctgggatatcctgtgctggttcgtgcggcctttgccctgggtggcctg
ggctctggctttgcctccaacagggaggagctctctgctcttgtggccccagcttttgcc
catactagccaagtgctggtagataagtccctgaagggatggaaggagattgagtacgaa
gtggtgagagatgcctatggcaactgtgtcacggtgtgtaacatggagaatttggaccca
ttgggcatccacactggagaatccatagtcgtggctccaagccagacactgaatgacagg
gaataccagctactgcggcagacagccatcaaggtgacccagcaccttggaatcgtcggg
gaatgcaatgtgcagtacgccttgaaccccgagtctgagcagtattacatcattgaagtg
aatgccaggctctctcgaagctctgccctggccagtaaggccacaggttatccactggcc
tatgtggcagcgaagctagcattgggcatccctctacctgagctcaggaactcagtgaca
gggggaacagcggcttttgaacctagcctggattattgtgtggtaaagatccctcgctgg
gacctcagcaagttcctccgtgtcagcacaaagatcgggagctgcatgaagagcgtcggt
gaagtcatgggcattgggcgttcttttgaggaagccttccagaaggctcttcgcatggta
gatgagaactgtgtgggctttgatcacacagtaaagccggtcagtgacatggaattggag
acgccaactgataagcggatctttgtggtagcagctgctctgtgggctggctattctgtg
gagcggctgtatgaactcacacgcatcgaccgctggttcctgcaccggatgaagcggatt
atagcacacgcccagctgctggaacagcaccgtggacagcctttgcccccagacctgcta
caccaggccaagcgccttggcttctcagacaagcagatcgcccttgcggttctgagcaca
gagctggcggttcgcaaactgcgtcaggagttgggaatctgcccagcagtgaaacagatt
gacacagttgcagctgagtggccagcccagacaaattatttgtacctgacatactggggc
accacccatgatctcacctttcgaacgcctcacgtcctggtccttggctctggcgtctac
cgtataggctccagcgttgagtttgactggtgtgctgtgggctgcatccggcagctccga
aagatgggatataagaccatcatggtgaactacaacccagagacagtcagcactgactat
gacatgtgtgaccgactctactttgatgagatctcttttgaggtggtgatggacatctat
gagctagagaaccctgaaggtgtgatcctatctatgggtggacagctgcccaacaacatg
gccatggctctgcatcggcagcagtgccgggtgctgggtacttcccctgaagccatcgac
tcggctgagaaccgtttcaagttctcccggctcctcgacaccattggtatcagccaacct
cagtggagggaactcagtgacctagagtctgctcgccagttctgccagacagtggggtac
ccctgcgtggtgcgcccctcctacgtgctgagtggcgctgctatgaatgtggcctacact
gacggcgacctggagcgcttcctgagcagtgcagcagccgtctctaaggagcaccctgtg
gtcatctccaagttcatccaggaggctaaggagattgatgtggatgctgtggcccgtgat
ggtgtagtggcagccattgccatctctgagcatgtggagaatgcaggagtgcattcaggc
gatgccacactggtgaccccaccgcaggacatcactgccaaaaccctggagcggattaaa
gccattgtgcacgctgtgggtcaggagctgcaggtcacaggacccttcaatctgcagctc
attgccaaggatgaccagctgaaagttatcgaatgcaacgtgcgtgtctctcgctccttc
cctttcgtctcgaaaacactaggtgtggacctagtagccttggccacacgcgtcatcatg
ggggaagaagtggaacctgtggggctcatgactggctccggagtcgtgggggtaaaggtg
cctcagttctccttctcacgcttggcgggtgctgatgtggtgttgggtgtggagatgacc
agtaccggggaagtggctggcttcggggagagccgttgcgaggcctacctcaaggccatg
ctaagcactggctttaagatccccaagaagaacatcttgctgaccattggcagctataag
aacaaaagtgagctgctcccaactgtgcggctgctggagagcctgggctacagcctctac
gccagcctgggcactgctgacttctacactgagcatggtgtcaaggtaacagctgtggac
tggcactttgaggaggcagtggatggtgagtgcccaccgcagcgaagcatcttggagcag
ctggctgagaatcactttgagctagtgattaacctgtcaatgcgtggagctgggggccgg
cgtctctcttcctttgtcaccaagggctaccgtacccggcgcctggccgctgacttctct
gtgcctctcatcatcgatatcaagtgcaccaaactgtttgtagaggccctaggccagatt
gggccagcccctcctttgaaggtgcacgttgactgtatgacttcccaaaagcttgtgcga
ctacctggactgattgacatccatgtgcacctgcgggaaccaggggggacacacaaggag
gactttgcctcaggcacagctgctgccttggctgggggcgtgaccatggtgtgtgccatg
cctaatacccggccccctatcattgatgcccctgccctggccctggcccagaagctggca
gaggctggcgcacgctgtgactttgccttatttcttggggcctcgtcagaaaatgcaggg
accctgggtgctgtggctgggtctgctgctgggctaaagctctacctcaacgaaaccttc
tctgagcttcggctggacaacgtggcccagtggatggagcactttgagacatggccatcc
cacctccccattgtcgcccatgcggagcgacagagtgtcgccgccatcctcatggtggcc
cagctgacccagcgctcagtgcacatatgtcatgtggcacggaaggaggagatcctgctg
attaaagccgcaaaggcccgagggctgccagtgacctgtgaggtggcgccccaccatctg
tttctaagccgcgatgacctggagcgcctggggcccgggaagggcgaggtccggcctgag
cttggctcccgccaggatgtggaggccctgtgggagaacatggctgtcatcgactgcttc
gcctcagatcatgccccccacaccttggaggagaagtgtgggcccaggcctccaccaggc
ttcccggggctggagaccatgctgccgctgctgctcacggctgtcagcgagggccggctc
actctggatgacctactgcagcggctgcaccacagtcctcggcggatcttccacctgccc
ccacaggaggacacctatgtggaggtggatctggagcatgaatggaccatccccagccac
atgcccttctccaaggcccactggacacccttcgaagggcagaaggtcaagggcaccgtc
cgccgtgtggtcctacgaggcgaggtggcctatattgacgggcaggtcctggtgcccccg
ggctacggacaggatgtacgcaagtggcctcagggggttgttccccagctcgcacctcca
gcccctgccaccagtgagataaccacgacacccgaaaggcctcgccgggctatcccaggg
cttcccgatggccgcttccacctgcctccccgaatccaccgagcctctgacccaggtctg
ccagctgaagagccaaaggaaaagtcctctcggaaggcagctgaaccagagctcatggga
acccttgatggcacctgctaccctccaccaccagtacctagacaggcgtcaccccagaac
ctggggacccctggcctgctgcacccccagacctcacccctgctgcactcattagtgggt
caacatatcctgtctgtccagcagttcaccaaggatcagatgtctcacctgttcaatgtg
gcacacacactgcgtatgatggtacagaaggagcggagcctcgacatcctcaaggggaag
gtgatggcctccatgttctacgaggtgagcacgcggaccagcagttcctttgcggcagcc
atggcccggctggggggcgctgtgctcagcttctcagaagccacgtcttcagtccaaaag
ggtgaatccctggctgactctgtgcagaccatgagctgctacgccgacgttgttgtgctt
cggcatccccagcctggagccgtggagctggcagccaagcactgtcgaaggccagtgatc
aatgctggcgatggggttggagagcatcccacgcaggccctgctggacatcttcaccatc
cgggaggagcttgggactgtcaatggcatgacgatcacaatggtgggggacctgaagcat
ggacgcacggtgcattccctggcctgcctgctcacccagtaccgtgtcagcctgcgctac
gtggcacctcccagcctgcgcatgccacccaatgtgcgggcctttgtggcagcccgcggc
accaagcaggaggaatttgagagcattgaggaagcgctgcctgacactgatgtgctctac
atgactcgaatccagaaggaacgctttgactctagtcaggagtatgaagcttgctttggc
cagttcattctcactccccacatcatgacgcgggccaagaagaagatggtggtgatgcac
ccgatgcctcgagtcaatgagataagcgtggaggtggactcagacccccgagcagcctac
ttccgccaggccgagaacggcatgtacatacgcatggctctgttagccactgtgctgggc
cgcttctag

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