KEGG   Pleurodeles waltl (Iberian ribbed newt): 138295357
Entry
138295357         CDS       T10800                                 
Symbol
CAD
Name
(RefSeq) multifunctional protein CAD isoform X1
  KO
K11540  carbamoyl-phosphate synthase / aspartate carbamoyltransferase / dihydroorotase [EC:6.3.5.5 2.1.3.2 3.5.2.3]
Organism
pwl  Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00220  Arginine biosynthesis
pwl00240  Pyrimidine metabolism
pwl00250  Alanine, aspartate and glutamate metabolism
pwl01100  Metabolic pathways
pwl01240  Biosynthesis of cofactors
Module
pwl_M00051  De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Brite
KEGG Orthology (KO) [BR:pwl00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00240 Pyrimidine metabolism
    138295357 (CAD)
  09105 Amino acid metabolism
   00250 Alanine, aspartate and glutamate metabolism
    138295357 (CAD)
   00220 Arginine biosynthesis
    138295357 (CAD)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:pwl01002]
    138295357 (CAD)
Enzymes [BR:pwl01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.3  Carboxy- and carbamoyltransferases
    2.1.3.2  aspartate carbamoyltransferase
     138295357 (CAD)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.2  In cyclic amides
    3.5.2.3  dihydroorotase
     138295357 (CAD)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.5  Carbon-nitrogen ligases with glutamine as amido-N-donor
    6.3.5.5  carbamoyl-phosphate synthase (glutamine-hydrolysing)
     138295357 (CAD)
Peptidases and inhibitors [BR:pwl01002]
 Cysteine peptidases
  Family C26: gamma-glutamyl hydrolase family
   138295357 (CAD)
 Metallo peptidases
  Family M38: beta-aspartyl dipeptidase family
   138295357 (CAD)
SSDB
Motif
Pfam: CPSase_L_D2 CPSase_L_D1 GATase CPSase_sm_chain OTCace_N OTCace CPSase_L_D3 ATP-grasp MGS Dala_Dala_lig_C ATPgrasp_Ter Amidohydro_1 DHOase ATP-grasp_3 GARS_A Peptidase_C26 GSH-S_ATP
Other DBs
NCBI-GeneID: 138295357
NCBI-ProteinID: XP_069089694
LinkDB
Position
5:complement(70022926..70640357)
AA seq 2292 aa
MASLQLEDGSLFRGQPFGAPVSVSGEVVFQTGMVGYPEALTDPSYKSQILVLTYPLVGNY
GIPHDEHDEFGLSRWFESSHIHTSALIVGEKSENPSHWCAALSLDQWLKEHNIPGLEGVD
TRALTKKIREKGTMLGKLILDGTEEGTVPLEDPNTRNLVKEVSLKEPQVYNPGGSLKIAA
LDCGLKYNQIRCLCQRGAAVTVVPWNHPLDSKDFDGLFISNGPGDPVFCQEAVDNIRRIV
SEEQPKPVFGICLGHQILSLVIGAKTYKLKYGNRGHNQPCIHEDTQRCFITSQNHGFAVD
PTTLPKGWSALFTNANDRSNEGVVHETKPFFSVQFHPEHRAGPMDLVGLFDVFLDTVRDL
KNGSPCGKTVKKRLREMLTYENSPDVGVLADSRPTKVLILGSGGLSIGQAGEFDYSGSQA
IKALKEEKIQTVLINPNIATVQTSKGLADKVYFLPLTADYVTEVIKNERPDGVLLTFGGQ
TALNCGVELTKLGVLERYNVRVLGTPVSSIEMTEDRKVFVEKMEEISEHVAPSEAAFSLE
QAVAAAERIGYPVLVRSAYALGGLGSGFANTKEELAALVSQAFAHTTQVLVDKSLKGWKE
IEYEVVRDAYNNCITVCNMENVDPLGIHTGESIVVAPSQTLNDREYNILRNTAIKVIQHL
GIVGECNIQYALNPESEQYYIIEVNARLSRSSALASKATGYPLAYVAAKLALGIPLPVLR
NSVTNSTTANFEPSLDYCVVKIPRWDLSKFLRVSTKIGSSMKSVGEVMAVGRNFEEALQK
ALRMVDENCVGFDHTLKPASDMELETPTDKRIFVLAAALRAGYNIDRLYDLTKIDRWFLH
KMKNITDHASMLETYRQDESKMPSEVLLKAKQLGFSDKQIAQAVHSTELAVRKLRHHWKI
LPVVKQIDTVAAEWPAQTNYLYLTYNGIEHDLGFTEPHVMVIGSGVYRIGSSVEFDWCAV
GCIQELRKMGFKTIMVNYNPETVSTDYDMCDRLYFDEISFEVVMDIYELENPEGIILSMG
GQLPNNIAMALHRQQCRILGTSPEAIDSAENRFKFSRMLDTIGISQPQWKELSDMESAKQ
FCSKVGYPCVVRPSYVLSGAAMNVAYSDSDLEKFLSSAVAVSKEYPVVISKFIQEAKEID
VDAVACDGLVVAIAICEHVENAGVHSGDATLVTPPQDITQKTLERIKAIVHAIGQELQVT
GPYNLQLIAKDDQLKVIECNVRVSRSFPFVSKTLGVDMVALATQVIMGEEVESVGLMKGT
GIVGVKVPQFSFSRLAGADVVLGVEMTSTGEVACFGENRYEAYLKAMLSTGFKIPKKNVL
LTIGSYKNKCELLTTVRTLESLGYGLYASLGTADFYTEHDIKVKAVDWPFEESDNDCPLK
EKQPSIMDYLSENHFDMVINLSMRNAGGRRLSSFVTKGYRTRRMAVDYSVPLIIDIKCTK
LFVEALRQIGAAPPVKTHVDCMTSQKLIRLPGFIDVHVHLREPGATHKEDFSSGTAAALA
GGVTMVCAMPNTSPAIIDSASFSLAHKLAESGARCDFAIFVGASSDNASMLTPIAACAAG
LKLYLNDTFSDLKMDNVSLWMEHFEKWPKHLPIVAHAEKQTVAAILMVAQLYQRSVHICH
VAKKEEILIIKAAKQKGIQVTCEVAPHHLFLCQDDLGLIGTARGQVRPMLGTREDLEALW
ENLESIDCFATDHAPHTVEEKSSKDPPPGYPGLETMLPLLLTAVSEGRLTIDDIIKRLYE
NPRKIFSLPVQENTYIEVDLEHEWVIPSHMQFTKSKWTPFEGMKVKGAVRRVILRGEVAY
IDGQVLAPPGFGQDVRKWPSTLVSQQPKVPAPVMEVPKTPEHPRHTVQSEVIRSRAPSPR
RMGPAGDGRFHLPPRIHRASDPGLPDPEFPVIVFSSGTVCSACGTAAPGLLLPCDLSAGF
PSYTSVGTGTLDPEELKEKLQKKSEETELAFLQDGYPHPPPLPRINSPQSLAMQSGPHPQ
ISPLLHPLIGQHVLSVKQFTKEQMSHLFNVAHTLRMMVQKERSLDILKGKVMASMFYEAS
TRTCSSFCSAMYRLGGSVINFSESTSSALKGENLVDSVQTMSCYADVMVLRHPQPGAVEL
AAKLCRKPVINAGDGVGEHPTQALLDVFTIREELGTVNGMTITMVGDLKHGRTVHSLACL
LTQYRVNLRYVTPKNLRMPSEIIHFVASKGIKQEEFENIEEALLDTDVLYMTRIQKERFN
TVEEYDACFGQFILTPHIMTRAKKKMVVMHPLPRVNEISFEVDSDPRAAYFRQAENGMYI
RMALLATVLGKF
NT seq 6879 nt   +upstreamnt  +downstreamnt
atggcctctctgcagctggaggatggctctctcttccgggggcagcccttcggggccccg
gtctcggtgtccggggaagtggttttccagactggcatggtggggtatccagaggccctg
actgacccgtcctacaaatcgcagatcttggtgctcacttaccccctcgtaggaaactat
ggcatccctcatgacgaacacgatgagtttgggctgagccggtggtttgaatcaagccac
atccacacatcagccctcatcgtgggtgagaagtcagaaaatccaagccactggtgcgct
gctctctccttggatcagtggcttaaggagcacaacatcccaggactcgaaggagtcgac
accagggccttgacaaagaagattcgggagaagggaactatgctggggaagttgatcttg
gatggaacagaggagggcactgttccacttgaagatcccaacactaggaatttggtgaaa
gaggtttcattgaaggaaccacaagtttacaaccctggaggctccttgaagattgcggct
ctagactgtgggctcaagtacaaccagatccgctgtctgtgccagagaggagcagctgtg
accgtggttccctggaaccatcccctggattccaaagattttgatggtttgtttattagc
aatgggccaggggacccggtcttctgccaagaagcagtggacaacatccggcgaattgtc
tctgaagagcagcccaagccagtgttcggtatctgcctgggacaccagatcctctcactg
gtcattggggccaagacctataaacttaagtacgggaatcgtggccacaaccagccgtgc
attcatgaggatacgcagcgctgcttcatcacttctcagaaccatggctttgctgtggac
ccaaccactcttcccaagggctggtctgcgctcttcaccaacgccaacgaccgctctaac
gagggtgtcgttcatgagaccaaaccattcttcagtgtccagttccatccggaacacaga
gctgggcccatggacctggttggcctctttgatgtgttcttggacacagtccgtgatctg
aaaaatgggagcccgtgtgggaagacagtgaagaaaaggttgcgggagatgctgacatat
gaaaattcaccggatgtgggggtcctggctgattctcggcccaccaaagttctaatcctt
ggctctggagggctctccattgggcaggccggggagttcgactactctggctcccaggca
atcaaagctttaaaagaagagaaaatccagacagttctgataaatcccaacattgccaca
gtacagacgtccaagggcctggccgacaaggtgtactttctccccctcacagcagattat
gtcactgaggtcatcaagaatgaacgcccggatggggtcctgcttactttcggtggtcag
acagccctgaactgcggggtagagttaaccaagctgggtgtgctggagcgctacaacgtg
cgggtgctgggcactcccgtctcatccatcgagatgacggaggaccgcaaggtgttcgtg
gagaagatggaggagatcagcgagcacgtggcgcccagcgaggctgccttctcactggag
caggccgttgctgcagctgagcggataggataccctgtccttgttcgatctgcttatgcc
ctgggtgggttgggctcaggctttgccaacacgaaggaagaacttgcagcccttgtgtca
caagcatttgcacacaccacccaggtcctggtggacaagtcactgaaaggctggaaggag
atagagtacgaggtggtccgggatgcctacaacaactgcataacggtttgcaacatggag
aacgtcgacccattgggcattcacactggagagtccattgtcgtggctccaagccagacg
ctcaatgatcgtgagtacaacatcctgcgcaacacagccatcaaggtcattcagcacctg
ggcattgtgggagaatgcaacatccagtatgcgctcaatccagagtctgagcagtattat
atcatcgaggtgaacgcccgtctgtccaggagttcagctctggcgagcaaggccactggc
tatcctctggcatatgtggcagctaaactggcactgggaatccccctccccgttctccgg
aactctgtcactaactctaccacagccaactttgagcccagcctggattactgtgtggtg
aagattccccggtgggacctcagcaagttccttcgggtcagcacaaagatcggaagctcc
atgaagagcgtgggggaggtcatggctgttgggcggaattttgaggaagctttgcagaaa
gccttgcggatggtggacgagaactgcgtgggctttgatcacactctgaaacctgcctcc
gacatggagcttgagacccccacagataaacgaatatttgtgctggcagctgctctgaga
gctggctataacatcgaccgtctctacgacttgaccaagattgaccgctggttcctgcac
aaaatgaaaaacatcactgaccatgcaagcatgctggagacctatcgccaggacgagagc
aagatgccctccgaggtgctcctgaaagccaaacagttgggattttcagacaaacaaatc
gctcaggcagtgcacagcacggagctagccgtgcgaaagctgaggcatcactggaagatc
ctgccggtggtgaaacagatcgacactgtcgctgccgagtggccggcccagactaactac
ctttatctgacgtacaacgggattgagcacgacctgggctttaccgaaccccacgtcatg
gtgattggatctggtgtttaccgcattgggagcagtgttgagtttgactggtgcgcagtg
ggatgtatccaggagctccgcaaaatgggcttcaagacaattatggttaactacaaccca
gagactgtcagtacagattatgacatgtgtgaccgattgtacttcgatgagatctcgttt
gaggtggtgatggacatctacgagttggagaaccccgaaggtattatcctctccatgggt
ggccaactgcccaacaacatcgccatggcattgcaccggcagcagtgccgaatcctgggc
acctctcccgaggccattgactctgctgagaaccgcttcaagttttcccgcatgctggac
accataggcatcagtcagccgcagtggaaggaactttctgatatggagtctgccaagcag
ttctgctccaaagtggggtacccatgtgtggtgcgtccctcctatgtactaagcggggct
gctatgaatgtagcatactctgacagcgatctggagaagttcctcagcagcgccgtggca
gtgtccaaggagtacccagtggtcatctccaagttcatacaggaagctaaggaaattgat
gttgatgctgttgcctgtgatggacttgtggttgccattgccatctgcgaacatgtggag
aacgcaggtgtacattcaggcgacgccacgctggtcacgcccccccaggatatcacgcag
aagaccctggagagaatcaaggccattgtgcatgccatcggacaggagcttcaagtcaca
ggtccctacaatcttcagctgatcgccaaggatgaccagctgaaagtgattgagtgcaac
gtgagggtgtctcgctcttttccctttgtctcgaagacccttggggtggatatggtggcc
ctggccacgcaagtcattatgggagaagaagttgagtctgtcggcctgatgaagggaaca
ggcattgtgggagtcaaggtgccacaattttccttctccaggctggcgggggcagatgtg
gtgctgggtgtggagatgaccagcactggggaagtggcctgctttggggaaaaccgttac
gaggcgtaccttaaagccatgctgagcaccggctttaagatcccgaagaagaatgtgctg
ctgaccattgggagctacaagaacaagtgcgagctgctcaccactgtgaggacgctggag
agccttggctatgggttgtacgccagtcttggaactgctgatttctacacagaacatgat
ataaaggttaaggcagtggactggcccttcgaggagtctgacaacgactgccccctgaaa
gagaagcagcctagcatcatggactacctttctgagaaccactttgacatggtcatcaat
ctctccatgcggaatgctggggggcgtcgcctctcatccttcgtaaccaaaggttaccgt
acaagacgaatggcggtcgactattcggtacccttgatcatcgatatcaagtgcaccaag
ctgtttgtagaggcgctgcgacagattggggcggctcctccagtgaagacgcatgtggac
tgtatgacatctcagaagctcattcgtctgccaggtttcattgatgtgcatgtccacctc
cgtgaacccggcgccacgcataaagaagacttttcttctggcacagcagcggcattagca
ggcggtgtcaccatggtgtgcgctatgcccaacacctcccctgccatcatagactctgct
tccttctcgctggcacataagttggctgaatccggggctcgatgtgactttgctatcttt
gtcggagcatcttctgataacgccagcatgttgacaccaattgcagcctgtgccgctggg
ctcaagctgtatctgaatgacaccttttctgatctcaaaatggacaatgtgtcactttgg
atggagcatttcgaaaagtggccgaagcatcttcccatcgtggcgcatgcagagaagcag
actgttgctgctattctgatggtggctcagctgtaccagcgctcggttcacatctgccat
gtggctaaaaaggaagagatcctgattattaaagctgccaagcagaagggcattcaggtc
acctgtgaggtggccccccaccacctcttcctgtgccaggatgatctgggcctcataggc
acagcacgtgggcaagtgcgccctatgctgggcacccgcgaagacctggaggccttgtgg
gaaaacctggagtctattgattgctttgccactgatcatgcacctcatactgtggaagag
aaaagtagcaaggacccgcctccaggctatcccggactagagaccatgctgccgctgctc
ctgaccgccgtatctgaagggcgtctgaccatagatgatatcatcaaacgactgtatgaa
aaccctcgcaagatcttctcgctgccagtgcaggagaacacctacatagaggtcgacctg
gagcatgagtgggtcatacccagtcacatgcagttcaccaaatccaagtggacacccttc
gagggcatgaaggtgaaaggagcagtacgaagggtgatcctacgtggagaagtcgcctat
atcgatggtcaggtgttggctcctccaggattcggacaggatgtgaggaagtggccatct
acactggtgtcacagcagcctaaagtgcctgctcctgtgatggaggtgcctaagactcca
gaacatccccgccatacggtgcagagtgaggttatccgcagcagagctccgagtccgcgc
aggatgggccccgccggtgacggacgcttccacctgcctccccgcattcatcgagcatcc
gacccagggctcccagacccagaattcccggtcattgtcttcagttcgggtactgtatgc
tcagcatgtggcactgctgccccggggcttctgctgccctgtgatctctctgcaggtttc
ccttcgtatacatctgttgggactggtacacttgaccctgaagagctgaaggaaaagctg
cagaagaaatcagaagagacagagcttgcattccttcaggatggatatcctcaccctcct
ccactgcctagaatcaactcccctcagagcctggccatgcagagtggtccacacccgcag
atctcgccgctgctccatcccctcatcggtcagcacgtgctgtctgtcaagcagttcacc
aaggagcagatgtcgcatctcttcaatgtggcgcacaccttgcgaatgatggtgcagaag
gagaggagtctggacattctgaaggggaaggtgatggcctccatgttttatgaggccagt
accagaacatgcagctccttctgttcggccatgtatcgccttggaggatcagtgatcaac
ttctctgaatcgacatcgtctgcactgaaaggagagaatttggtggactctgtgcagacc
atgagttgttatgctgatgtgatggtgctgcgccatccccagccgggggcggtggagctt
gctgcaaagctctgtcgcaaacctgtcatcaatgctggagatggggtgggagaacacccc
acacaagctttgttggatgtctttaccatccgggaagaactgggaactgtcaatgggatg
actatcactatggtcggggacctgaagcatggtcgtaccgtgcactcactggcatgtctg
ctgacccagtaccgtgtgaatctgcgctacgtcacccccaagaacctgcgcatgccgtca
gagatcatacactttgtagcttctaagggaattaagcaggaagagtttgagaacatcgaa
gaggctcttcttgacactgatgtcctgtacatgacccgtatccagaaggagaggttcaat
actgtggaggagtacgatgcttgttttggacagtttattcttactccacacattatgacc
agagcgaagaaaaagatggtggtgatgcatccccttcctcgtgtgaacgagatcagcttc
gaagttgactcagacccgagagctgcctattttcgtcaggctgagaatggcatgtacatt
cggatggctttgttggccacagtgctcggcaagttctaa

DBGET integrated database retrieval system