Puma yagouaroundi (jaguarundi): 121037018
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Entry
121037018 CDS
T07555
Symbol
PLCE1
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 isoform X1
KO
K05860
phosphatidylinositol phospholipase C, epsilon [EC:
3.1.4.11
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu00562
Inositol phosphate metabolism
pyu01100
Metabolic pathways
pyu04014
Ras signaling pathway
pyu04015
Rap1 signaling pathway
pyu04020
Calcium signaling pathway
pyu04024
cAMP signaling pathway
pyu04070
Phosphatidylinositol signaling system
pyu04919
Thyroid hormone signaling pathway
pyu04933
AGE-RAGE signaling pathway in diabetic complications
pyu05205
Proteoglycans in cancer
Module
pyu_M00130
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
121037018 (PLCE1)
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
121037018 (PLCE1)
04015 Rap1 signaling pathway
121037018 (PLCE1)
04020 Calcium signaling pathway
121037018 (PLCE1)
04070 Phosphatidylinositol signaling system
121037018 (PLCE1)
04024 cAMP signaling pathway
121037018 (PLCE1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
121037018 (PLCE1)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
121037018 (PLCE1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
121037018 (PLCE1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pyu04131
]
121037018 (PLCE1)
Enzymes [BR:
pyu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
121037018 (PLCE1)
Membrane trafficking [BR:
pyu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
121037018 (PLCE1)
Endocytosis
Macropinocytosis
Phospholipase C
121037018 (PLCE1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PI-PLC-X
PI-PLC-Y
RasGEF
RA
C2
EF-hand_like
Motif
Other DBs
NCBI-GeneID:
121037018
NCBI-ProteinID:
XP_040341835
LinkDB
All DBs
Position
Unknown
AA seq
2315 aa
AA seq
DB search
MTSEEMAASVLTPVTQRKVTSSQSALDESSEKVSDVSVPKAHSVRQSGQTSTISRLNKLK
EESSGSNLPEIVSIAREKIMSDENSNEKYWEESMPDSVKNLNINCNNVLKNSQCSLPQSQ
CYDTCDSVMEEGLCLETGIPSSLERKVFPGIQLEVDGPPMDISPLGNQSAIIESGRAHPD
GGLAAFHFHYEVDRRMSDTFCTLSDNLILDDCGNCVPLPGVRGERQKNYMAYTCKLMELA
ENCDNKNGQLQCDHCDALNDRYLCFEASCQRADAVCSSDSFCREDLTNSPPAKTFLSHFE
DFPDNCEDVEEDFFKSKKERSTLLVRRFCKNDREVKKSVYTGTRAIMRTLPSGHIGLGAY
SYIDQKRSGLLLPCGRVLERWSAVAVREDGSWCLSEAQWYSIYNAVRRREEIENTIGSLL
HFFTKLPASETAHEKIRVGPCLKQCVRDTICEYRATLQRTSISQYIAGSLLEATTSLGAR
SGLLSTFGGSAGRMMLKERQPGTSMANSSALPSSSAGISKELIDLQPLIQFPEEVASILM
EQEQNIYRRVLPVDYLCFLTRDLGSPECQTSLPCLKASISASILNSQNGEHNALEDLVMR
FNEVSSWVTWLILTAGSMEEKREVFSYLVHVAKCCWNMGNYNAVMEFLAGLRSRKVLKMW
QFMDQSDLETMRSLKDAMAQHESSCEYKKVVTRALHIPGCKVVPFCGVFLKELCEVLDGA
SGLMKLCPRYNSQEETLEFVADYSGQDNFLQRVGHNGLKNSEKESTVNSIFQIIRSCSRS
LEAEEEDSPSEGNSSRKNSLRDKARWQFIIGDLLDSENDIFEKSKEWDTHGSEEPQKAFD
HGTELIPWYVLSIRADVHQFLLQGATVIHYDQDTHLSARCFLQLQPDNSTLTWTKPTTAS
LASAKAKLGVLSNTSEPGKFPLLGNAGLSGLAEGVLDLFSAKAVYMGHPSIDIHTVCVQN
KLGSMFLSETGVTLLYGLQTTDNRLLHFVAPRHTAKMLFSGLLELTRAVRKMRKFPDQRQ
QWLRKQYVSLYQEDGRYEGPTLAHAVELFGGRRWSTRNPSPGTSAKSAEKPNVQRNNTLG
ISTTKKKKKILIRGESGEAADDEMATRKAKMHRECRSRSGSDPQDMNEQEESEANAIMSP
PNTLPSRRAHSLTTAGSPNLSAGTSSPNRPVSSPVLSSSNKSPSSAWSSSSWHGRIKGGM
KGFQSFMVSDSNMSFVEFVELFKSFSVRSRKDLKDLFDVYAVPCNRAGSESVPLYTNLTI
DENTSDLQPDLDLLTRNVSDLGLFIKSKQQLSDNQRQISDAIAAASIVTNGTGVESTSLG
VFGVGILQLNDFLVNCQGEHCTYDEILSIIQKFEPSVSMCHQGLLSFEGFARFLMDKDNF
ASKNDESQENIKELQLPLSYYYIESSHNTYLTGHQLKGESSVELYSQVLLQGCRSVELDC
WDGDDGLPIIYHGHTLTTKIPFKEVVEAIERSAFVNSDLPIIISIENHCSLPQQRKMAEI
FKSVFGEKLVAKFLFESDFSDDPMLPSPDQLRRKVLLKNKKLKAHQTPVDILKQKAHQLA
SMQAQAYNGGNANPPPANNEEEEDEEDEYDYDYESLSDADVLTASPAPNSQEDNILEDRP
ENKSCNDKLQFEYNEEIPKRIKKADNSACNKGKVYDMELGEEFYLPQNKKESRQIAPELS
DLVIYCQAVKFPGLSTLNASGSSRGKERKSRKSIFGNNPGRMSPGETASFNKASGKSSCE
GMRQAWEESSSPLNPTTSLSAIIRTPKCYHISSLNENAAKRLCRRYSQKLIQHTACQLLR
TYPAATRIDSSNPNPLMFWLHGIQLVALNYQTDDLPLHLNAAMFEANGGCGYVLKPPVLW
DKNCPMYQKFSPLERDLDNMEPAIYSLTIVSGQNVCPSSSTGSPCIEVDVLGMPLDSCHF
RTKPIHRNTLNPMWNEQFLFRVHFEDLVFLRFAVVENNSSAVTAQRIIPLKALKRGYRHL
QLRNLHNEVLEISSLFINSRRMEENSSSSTTPASLMFNSEERKCLQAHRVTVHGVPGPEP
FTVFSISGGTKAKQLLQQILTTEQDTKPIITDYFLMEEKYFISKEKNECRKQPFQRVIGP
EEEIMQILSSWFPEEGYVGRIVLKTQQENLEEKSIVQDDKEVTLSSEEESFFVQVHDVSP
EQPRTVIKAPRVSTAQDVIQQTLCKAKYSYSILSNPNPSDYVLLEEVVKDTTKKSSTPKS
SQRVLLDQECVFQAQSKWKGAGKFILKLKEQVQASREDKRKGISFASEFKKFTKSTKQPR
GLASPSQVLASEGVQNKEEKPVGSLSSSDTMDYRQ
NT seq
6948 nt
NT seq
+upstream
nt +downstream
nt
atgacttctgaagaaatggcagcttctgttctcacacctgtgactcaaagaaaggtgaca
tcgtctcagtcggctttagatgaaagtagtgaaaaggtctcagacgtcagtgttccgaag
gcacatagtgtcaggcagagtggtcagacttccaccatctcacgactgaacaagcttaaa
gaagaatcctctggaagcaacttgcccgagattgtctccatagcaagggagaagataatg
agtgatgagaacagcaatgagaagtactgggaggaaagcatgccagattctgtgaaaaac
ctcaatattaactgcaacaacgtactgaaaaacagccagtgcagccttcctcagagccag
tgttatgacacgtgcgattctgtcatggaggaaggcctgtgtttggaaactggaatccca
tcctcactggaaagaaaggtgttccctggaattcaactggaagtggacgggcctcccatg
gacattagtcccttaggaaatcagtcggccatcatagagagcggccgggcacaccctgac
ggcggcctggcagcatttcactttcattacgaagtcgacagaagaatgtcagacactttc
tgtaccttgtcagacaacctgattttggatgattgtggtaactgtgtaccactgcctggt
gttcgtggggagcgacagaaaaattatatggcatatacttgtaaactcatggaattggca
gaaaactgtgataataagaatgggcagctgcagtgtgatcattgtgatgccttaaacgac
agatacttgtgcttcgaagcttcttgccaaagggctgatgcggtatgttcaagtgacagc
ttttgcagggaggacttgactaacagtccacctgccaagacctttctgagccattttgag
gacttccctgataattgtgaagatgtagaagaagatttttttaagagcaaaaaggagagg
tccactttgttagtgagaagattttgtaaaaatgacagggaagtaaagaaatctgtatat
actgggacaagggcgatcatgagaactctgccttctggtcacattgggctgggagcttac
agttacattgatcagaagagaagtggtctcctgctgccctgtgggagagttctggaacgg
tggtcagcggtggcagttagggaagatgggagctggtgcctgtcagaagctcagtggtat
tcgatctacaatgcagtgagaaggagagaagaaatagaaaatacaattggatctcttctt
catttcttcacaaagctcccagcctccgaaacagcccatgaaaagattagggttggtccg
tgcttaaagcaatgtgtccgagataccatatgtgagtaccgtgccaccctccagaggacg
tccatatctcagtacatcgcgggttctctgctagaagcaaccacatctttaggagcaaga
agtggcctactcagtacctttggaggatccgccggacgaatgatgctaaaagaacgtcag
ccaggcacctccatggccaattctagtgccctcccttcaagttcagctgggatcagcaag
gagctgattgatctgcagcccctcattcagttcccagaggaagtcgccagcatcctgatg
gagcaggagcagaacatttaccgaagggtcttgccagttgactacctttgcttcttgacc
cgggacttgggctctccggaatgccagacatccctgccctgcctcaaagcgtccatctca
gcatcaattcttaactcccagaacggagaacacaatgccctggaagatcttgtgatgaga
tttaatgaggtgagctcctgggtaacgtggctgatcctcacggcgggctccatggaggag
aagcgagaagtcttctcctatttagtacacgtggccaaatgctgctggaacatgggcaac
tacaatgctgtcatggagttcttggccggcctcaggtcaagaaaagttttaaaaatgtgg
cagtttatggaccagtctgacctagagaccatgaggagcctgaaggatgccatggctcag
cacgaatcttcctgcgagtacaagaaggtggtcacgcgggctctgcacatacctggctgt
aaggtggttccgttctgtggggtgtttctgaaggagctctgtgaagtactggacggagcc
tccggcctcatgaagctttgcccgaggtacaattcccaagaagaaactctagagtttgta
gccgattacagtggacaagataatttcttacaacgagtgggacataatggcttaaagaat
tcggagaaggagtccacagtcaacagcatctttcagatcatcaggagctgcagccgaagt
ctggaggccgaggaggaggacagccccagtgaaggaaacagctccaggaaaaattcctta
agggataaagcccgatggcagtttatcattggagacctgttagattctgaaaatgacatc
tttgagaaatccaaagaatgggacactcacggatcagaagagccacagaaggcctttgac
catgggacagagctaatcccatggtacgtgctgtccatccgagccgatgtgcaccagttc
ctgctgcagggggccactgtcatccactacgaccaggacacgcacctctctgcccgatgc
ttcctccagcttcagcctgacaacagcaccttgacctggacaaagcccaccactgcttcc
ctggccagtgctaaagcaaaactcggtgtgcttagtaacacgtctgagcctggcaaattc
ccgttactgggcaatgctggactaagtggcctggcagagggggtcttggatctgttctca
gcaaaagctgtgtacatgggacaccctagcatcgatatacacactgtgtgtgttcagaac
aaactgggtagcatgtttctctcagagactggcgtgacgctgctctatgggctccagacc
acggacaatagattattgcactttgtggcacccaggcacacagctaagatgctcttcagt
ggattgctggaactcacgagagccgtgaggaagatgaggaagttccctgaccagaggcag
cagtggctgcggaaacagtacgtcagcctctatcaggaagatggacggtacgaaggccca
actttggctcacgccgtggagttgtttggtggcaggcggtggagtacacgaaaccccagc
cccgggacatcagcaaagagtgccgagaagcccaatgtgcagagaaacaacaccttgggc
ataagcactaccaagaaaaagaagaaaatccttataaggggtgagagcggagaggcagct
gacgatgagatggccacccgaaaagccaaaatgcacagagagtgtcgcagccggagtggt
tctgatcctcaagacatgaatgaacaagaagagtcagaggcaaatgccatcatgagccct
cctaacactctgccttccagaagagcccactctttgaccacggctgggtcccctaacttg
tctgccgggacatcatctcccaacaggccagtgtcttcccctgtgctgtcttcttcaaac
aagagcccgtccagtgcttggagcagcagcagctggcacgggcggatcaaaggcggaatg
aaaggtttccagagcttcatggtttcagacagtaacatgagctttgttgaattcgttgag
ctgttcaaatcattcagcgtgaggagccgcaaggacctgaaggacctcttcgacgtctac
gctgtgccctgcaaccgagccggctccgagtcggtgccactctacaccaacctaacaatt
gacgaaaacaccagcgatcttcagcctgacctagacttattgaccagaaacgtctcggat
ttggggttgttcattaagagtaaacagcagctgtcagacaaccagaggcagatatctgat
gccattgctgctgcaagtatcgtgacaaacggcactggggtcgagagcacatccttgggc
gtgtttggggttggcatcctccagctcaatgacttcctagtgaactgccaaggagaacac
tgcacttatgatgaaatcctcagcatcatccagaagttcgagcctagtgttagtatgtgt
catcagggcctactgtcatttgaaggatttgcaaggtttctgatggataaagataatttt
gcctccaaaaatgatgagtcacaggaaaacattaaagaactacagctgcctctctcctac
tattacattgaatcttcacacaatacctacctcacaggccaccaactcaaaggagagtcc
tcagtagaactctacagccaggtcctcctgcaaggctgtaggagcgtagagctggattgt
tgggatggagacgacgggttgcccatcatctatcatggacacacgctgacaaccaagatc
cccttcaaggaggtggttgaagccattgaacgcagtgcctttgtcaactctgacctgccc
atcatcatatcgattgagaaccactgctcattgcctcagcaacgaaaaatggcagaaatt
ttcaagagtgtgtttggagaaaaactggtggctaagttcctgtttgagagtgatttctca
gatgacccaatgcttccctcacccgaccaacttaggaggaaagtgctccttaaaaataag
aagctaaaagcccaccaaacaccagtggatatcttaaagcaaaaggctcatcagttagca
tccatgcaagctcaggcttacaatggtgggaatgccaaccccccaccggctaataacgag
gaagaggaggatgaagaagacgaatatgattacgactatgaatccctgtctgatgcagat
gtccttactgcttctcctgctcctaacagtcaggaagacaacattctagaagacagacct
gaaaataaatcatgtaatgacaagcttcagtttgagtataatgaagaaatccccaagagg
ataaagaaagcagataactctgcttgcaacaaaggaaaggtttatgacatggaactggga
gaagaattttatctccctcagaataaaaaggaaagcagacagattgcaccagagctctct
gaccttgtcatctattgtcaagcagtaaaatttccaggcctgtcaactctaaatgcatct
ggctctagcagaggaaaagaaaggaaaagcaggaagtccatttttggcaacaatccgggc
agaatgagccctggggagacagcatcgtttaacaaagcatctggaaaaagttcctgtgaa
ggaatgcgacaggcctgggaggaatcttcttcccccctcaacccaaccacatccctcagc
gctatcattagaactcccaaatgttaccatatctcctcgctgaatgaaaatgccgccaaa
cgtctgtgtcgcaggtattctcagaaactgatccagcacaccgcctgtcagctgctgagg
acttacccggctgccactcgcatcgactcctccaaccccaatcccctcatgttctggctc
catgggatacagctcgtggcgctcaactaccagacagatgatctccctttacatttaaat
gctgccatgtttgaagccaacggtgggtgtggttatgttttgaaacccccagttctgtgg
gacaagaactgtcccatgtatcagaagttctctcccttagaaagagatctggacaacatg
gagcctgccatctactccttaactattgtctctggtcaaaacgtgtgcccgagtagcagc
acaggaagcccgtgtatcgaagtcgatgtgctgggcatgcccctggacagctgccatttc
cgcacgaagcccatccaccggaacactctgaaccccatgtggaatgaacagtttctcttc
cgggttcactttgaagatctcgtatttcttcgttttgccgttgtggaaaacaacagctca
gctgtaactgctcagagaatcatcccactcaaggctttaaaacgaggatatcgacatctt
cagctgcgaaatctccacaacgaagtcttggaaatctctagtttattcataaacagtagg
aggatggaagaaaattcctccagcagcaccacgccggcctctttgatgtttaattcagaa
gaaagaaaatgtttgcaggctcacagagtcacggtgcatggggtcccaggtccagagccc
tttactgttttctccataagtggaggcaccaaagcaaagcagcttctccaacaaattctg
accactgaacaagacaccaaacctatcatcacagactattttttgatggaagaaaaatat
tttatatctaaagaaaagaatgaatgcaggaaacaaccgttccagagagtcattggtcca
gaggaagagattatgcagattttaagcagctggtttccagaggaaggatatgttggcagg
attgtcttaaaaacccagcaggaaaacctagaagagaaaagcattgttcaagatgacaaa
gaggtgaccttgagctcagaggaggagagtttctttgttcaagtgcacgatgtttctcca
gagcaacctcgaacggtcatcaaagcaccccgtgtcagcaccgcacaggacgtcattcag
cagaccttgtgcaaagcaaagtattcctacagcatcctgagcaatcccaacccaagtgac
tatgtgcttttggaagaggtggtaaaagacacgaccaagaagtcttccaccccaaagtcc
tcccagcgggtccttttggatcaggagtgtgtgtttcaagcccaaagcaagtggaaaggg
gcaggaaaattcatccttaagctaaaggagcaggtgcaggcatcccgagaagacaaaagg
aaaggcatttcttttgcaagtgaatttaagaagttcaccaagtcaactaaacaaccccga
ggactcgcatcaccttctcaggtcttggcctcagaaggtgtccaaaacaaggaggagaaa
cctgtgggcagcttgtcctccagtgacaccatggactatcgacaataa
DBGET
integrated database retrieval system
