KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108539989
Entry
108539989         CDS       T04641                                 
Symbol
IRAK4
Name
(RefSeq) interleukin-1 receptor-associated kinase 4
  KO
K04733  interleukin-1 receptor-associated kinase 4 [EC:2.7.11.1]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04010  MAPK signaling pathway
rbb04064  NF-kappa B signaling pathway
rbb04620  Toll-like receptor signaling pathway
rbb04621  NOD-like receptor signaling pathway
rbb04722  Neurotrophin signaling pathway
rbb04936  Alcoholic liver disease
rbb05132  Salmonella infection
rbb05133  Pertussis
rbb05135  Yersinia infection
rbb05140  Leishmaniasis
rbb05142  Chagas disease
rbb05145  Toxoplasmosis
rbb05152  Tuberculosis
rbb05161  Hepatitis B
rbb05162  Measles
rbb05164  Influenza A
rbb05168  Herpes simplex virus 1 infection
rbb05169  Epstein-Barr virus infection
rbb05170  Human immunodeficiency virus 1 infection
rbb05171  Coronavirus disease - COVID-19
rbb05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    108539989 (IRAK4)
   04064 NF-kappa B signaling pathway
    108539989 (IRAK4)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    108539989 (IRAK4)
   04621 NOD-like receptor signaling pathway
    108539989 (IRAK4)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    108539989 (IRAK4)
 09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    108539989 (IRAK4)
   05161 Hepatitis B
    108539989 (IRAK4)
   05171 Coronavirus disease - COVID-19
    108539989 (IRAK4)
   05164 Influenza A
    108539989 (IRAK4)
   05162 Measles
    108539989 (IRAK4)
   05168 Herpes simplex virus 1 infection
    108539989 (IRAK4)
   05169 Epstein-Barr virus infection
    108539989 (IRAK4)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    108539989 (IRAK4)
   05135 Yersinia infection
    108539989 (IRAK4)
   05133 Pertussis
    108539989 (IRAK4)
   05152 Tuberculosis
    108539989 (IRAK4)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    108539989 (IRAK4)
   05140 Leishmaniasis
    108539989 (IRAK4)
   05142 Chagas disease
    108539989 (IRAK4)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    108539989 (IRAK4)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    108539989 (IRAK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rbb01001]
    108539989 (IRAK4)
Enzymes [BR:rbb01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     108539989 (IRAK4)
Protein kinases [BR:rbb01001]
 Serine/threonine kinases: TKL group
  IRAK family
   108539989 (IRAK4)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Pkinase Pkinase_fungal Haspin_kinase Death RecA_C
Other DBs
NCBI-GeneID: 108539989
NCBI-ProteinID: XP_017744448
UniProt: A0A2K6MSR5
LinkDB
Position
Unknown
AA seq 461 aa
MNKPITPSTYVRCLNVGLIRKLSDFIDPQEGWKKLAVAIKKPSGDDRYNQFHIRRFEALL
QTGKSPTSELLFDWGTTNCTVGDLVDLLIQNEFFAPASLLLPDAVPKTANTLPSKEAVTV
QQKQMPFYDKDRTLMTPLQNLEQSYMPPDSSSPENKSLEVSDTRKFSQFSFYELKNVTNN
FDERPISVGGNKMGEGGFGVVYKGYVNNTTVAVKKLAAMVDITTEELKQQFDQEIKVMAK
CQHENLVELLGFSSDGDDLCLVYVYMPNGSLLDRLSCLDGTPPLSWHMRCKIAQGAANGI
NFLHENHHIHRDIKSANILLDEAFTAKISDFGLARASEKFAQTVMTSRIVGTTAYMAPEA
LRGEITPKSDIYSFGVVLLEIITGLPAVDEHREPQLLLDIKEEIEDEEKTIEDYIDKKMN
DADSTSIEAMYSVASQCLHEKKNKRPDIKKVQQLLQEMTAS
NT seq 1386 nt   +upstreamnt  +downstreamnt
atgaacaaacccataacaccgtcaacatatgtgcgctgcctcaatgttggactgattagg
aagctgtcagattttattgatcctcaagaaggatggaagaagttagctgtagctattaaa
aaaccatctggtgatgatagatacaatcagtttcacataaggagatttgaagcattactt
caaactggaaaaagtcccacttctgaattactgtttgactggggcaccacaaattgcaca
gttggtgatcttgtggatcttttaatccaaaatgaattttttgctcctgcgagtcttttg
ctcccagatgctgttcccaaaactgctaatacactaccttctaaagaagctgtaacagtt
caacaaaaacagatgcctttctatgacaaagacaggacattgatgacacctctgcagaat
cttgaacaaagctatatgccacctgactcctcaagtccagaaaataaaagtttagaagtt
agtgatacacgtaagttttcacagttttcattttatgaattgaagaacgtcacaaataac
tttgatgaacgacccatttctgttggtggtaataaaatgggagagggaggatttggagtt
gtatataaaggctacgtaaataacacaactgtggcagtaaagaagcttgcagcaatggtt
gacattactactgaagaactgaaacagcagtttgatcaagaaataaaagtaatggcaaag
tgtcaacatgaaaacttagtagaactacttggtttctcaagtgatggagatgacctctgc
ttagtgtatgtttacatgcctaatggttcattactagacagactctcttgcttggatggt
actccaccactttcttggcacatgagatgcaagattgctcagggtgcagctaatggcatc
aattttctacatgaaaatcatcatattcatagagatattaaaagtgcaaatatcttacta
gatgaagcttttactgctaaaatatctgactttggccttgcacgggcttctgagaagttt
gcccagacagtcatgactagcagaattgtgggaacaacagcttatatggcacctgaagct
ttgcgaggagaaataacacccaaatctgacatttacagctttggtgtggttttactagaa
ataataactggacttccagccgtggatgaacaccgtgaacctcagttattgctagatatt
aaagaagaaattgaagatgaagaaaagacgattgaagattatattgataaaaagatgaat
gatgctgattccacttcaattgaagctatgtactctgttgctagtcaatgtctgcatgaa
aagaaaaataagagaccagacattaagaaggttcaacagctgctgcaagagatgacagct
tcttaa

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