KEGG   PATHWAY: rn00531
Entry
rn00531                     Pathway                                
Name
Glycosaminoglycan degradation
Class
Metabolism; Glycan biosynthesis and metabolism
Pathway map
rn00531  Glycosaminoglycan degradation
rn00531

Module
M00076  Dermatan sulfate degradation [PATH:rn00531]
M00077  Chondroitin sulfate degradation [PATH:rn00531]
M00078  Heparan sulfate degradation [PATH:rn00531]
M00079  Keratan sulfate degradation [PATH:rn00531]
Other DBs
GO: 0006027
Reaction
R07805  keratan sulfate 1,4-beta-D-galactanohydrolase
R07806  N-acetyl-D-galactosamine 6-sulfate 6-sulfohydrolase
R07807   
R07808  N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase
R07809   
R07810   
R07811   
R07812  L-iduronate-2-sulfate 2-sulfohydrolase
R07813   
R07814   
R07815  acetyl-CoA:heparan-alpha-D-glucosaminide N-acetyltransferase
R07816   
R07817   
R07818   
R07819  N-acetyl-D-glucosamine-6-sulfate 6-sulfohydrolase
R07820   
R07821  L-iduronate-2-sulfate 2-sulfohydrolase
R07822   
R07823  N-acetyl-D-galactosamine-4-sulfate 4-sulfohydrolase
R07824   
R07825   
R10830  beta-D-glucuronoside glucuronosohydrolase
R10831   
R10905   
Compound
C00426  Dermatan sulfate
C00573  Keratan sulfate
C00634  Chondroitin 4-sulfate
C00925  Heparan sulfate
G00526   
G00711   
G00872  DWA-2
G01391   
G01945   
G01977   
G02632   
G09660   
G10008   
G10505  Hyaluronic acid
G12336   
G13034   
G13035   
G13036   
G13037   
G13038   
G13039   
G13040   
G13041   
G13042   
G13043   
G13073   
G13074   
Reference
PMID:27570
  Authors
Greiling H, Stuhlsatz HW, Cantz M, Gehler J
  Title
Increased urinary excretion of keratan sulfate in fucosidosis.
  Journal
J Clin Chem Clin Biochem 16:329-34 (1978)
DOI:10.1515/cclm.1978.16.6.329
Reference
PMID:3161730
  Authors
Fuchs W, Beck M, Kresse H
  Title
Intralysosomal formation and metabolic fate of N-acetylglucosamine 6-sulfate from keratan sulfate.
  Journal
Eur J Biochem 151:551-6 (1985)
DOI:10.1111/j.1432-1033.1985.tb09138.x
Related
pathway
rn00532  Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate
rn00534  Glycosaminoglycan biosynthesis - heparan sulfate / heparin
KO pathway
ko00531   
LinkDB

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