Rattus norvegicus (rat): 114495
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Entry
114495 CDS
T01003
Symbol
Map2k6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
KO
K04433
mitogen-activated protein kinase kinase 6 [EC:
2.7.12.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04015
Rap1 signaling pathway
rno04218
Cellular senescence
rno04380
Osteoclast differentiation
rno04620
Toll-like receptor signaling pathway
rno04664
Fc epsilon RI signaling pathway
rno04668
TNF signaling pathway
rno04750
Inflammatory mediator regulation of TRP channels
rno04912
GnRH signaling pathway
rno04935
Growth hormone synthesis, secretion and action
rno04936
Alcoholic liver disease
rno05014
Amyotrophic lateral sclerosis
rno05022
Pathways of neurodegeneration - multiple diseases
rno05132
Salmonella infection
rno05135
Yersinia infection
rno05145
Toxoplasmosis
rno05161
Hepatitis B
rno05163
Human cytomegalovirus infection
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05169
Epstein-Barr virus infection
rno05170
Human immunodeficiency virus 1 infection
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417
Lipid and atherosclerosis
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
114495 (Map2k6)
04015 Rap1 signaling pathway
114495 (Map2k6)
04668 TNF signaling pathway
114495 (Map2k6)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
114495 (Map2k6)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
114495 (Map2k6)
04664 Fc epsilon RI signaling pathway
114495 (Map2k6)
09152 Endocrine system
04912 GnRH signaling pathway
114495 (Map2k6)
04935 Growth hormone synthesis, secretion and action
114495 (Map2k6)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
114495 (Map2k6)
09158 Development and regeneration
04380 Osteoclast differentiation
114495 (Map2k6)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
114495 (Map2k6)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
114495 (Map2k6)
05161 Hepatitis B
114495 (Map2k6)
05163 Human cytomegalovirus infection
114495 (Map2k6)
05167 Kaposi sarcoma-associated herpesvirus infection
114495 (Map2k6)
05169 Epstein-Barr virus infection
114495 (Map2k6)
09171 Infectious disease: bacterial
05132 Salmonella infection
114495 (Map2k6)
05135 Yersinia infection
114495 (Map2k6)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
114495 (Map2k6)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
114495 (Map2k6)
05022 Pathways of neurodegeneration - multiple diseases
114495 (Map2k6)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
114495 (Map2k6)
05418 Fluid shear stress and atherosclerosis
114495 (Map2k6)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
114495 (Map2k6)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
114495 (Map2k6)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
114495 (Map2k6)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: STE group
STE7 family
114495 (Map2k6)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Seadorna_VP7
Pkinase_fungal
CLP1_P
Haspin_kinase
Choline_kinase
APH
DUF4344
Motif
Other DBs
NCBI-GeneID:
114495
NCBI-ProteinID:
NP_446155
RGD:
620666
Ensembl:
ENSRNOG00000004437
UniProt:
Q925D6
LinkDB
All DBs
Position
10:95373304..95490406
Genome browser
AA seq
334 aa
AA seq
DB search
MSQSKGKKRNPGLKIPREAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMRHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSK
ERPTYPELMQHPFFTVHEAKAADVASFVKLILGD
NT seq
1005 nt
NT seq
+upstream
nt +downstream
nt
atgtctcagtcgaaaggcaagaagcgaaaccccggccttaagattccaagggaagcgttt
gaacaacctcagaccagttccacgccgcctcgggatttagactccaaggcttgcatttct
attggaaaccagaactttgaggtgaaggccgatgacttggagcctatagtggagctggga
cgaggtgcgtacggggtggtggagaagatgcgtcacgtgcccagcgggcagatcatggcg
gtgaagcggatacgggccacagttaatagccaggagcagaaacggctactgatggatctg
gatgtttctatgaggacagtggactgtccgtttaccgtgaccttctatggtgcactcttc
cgggagggcgatgtgtggatctgcatggagctcatggatacgtcactagataaattctac
aaacaagttattgataaaggccaaacaattccagaagatatcttagggaagatagcagtt
tctattgtaaaagcattagaacatttacacagtaagctctctgttatccatcgagatgtc
aagccttcaaatgtgctcattaacacgctgggccaagtgaagatgtgtgactttggaatc
agcggctacctggtagactctgttgcgaaaacgatcgatgccggttgcaaaccatacatg
gctcctgaacgaataaatccagagctcaaccagaaggggtacagtgtgaagtctgacatt
tggagtctgggcatcaccatgattgagctggccatcctccggtttccctatgattcttgg
ggaacgcccttccagcagctaaaacaggtggtagaagagccgtctccacaactcccagcg
gacaagttctctgctgacttcgttgactttacctcacagtgcttgaagaaaaattccaaa
gaacggcccacgtatccagagcttatgcaacatccatttttcaccgtccatgaagccaaa
gcagcagatgtggcgtctttcgtaaaactgatactcggggactaa
Rattus norvegicus (rat): 303200
Help
Entry
303200 CDS
T01003
Symbol
Map2k3
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 3
KO
K04432
mitogen-activated protein kinase kinase 3 [EC:
2.7.12.2
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno04010
MAPK signaling pathway
rno04015
Rap1 signaling pathway
rno04218
Cellular senescence
rno04620
Toll-like receptor signaling pathway
rno04664
Fc epsilon RI signaling pathway
rno04668
TNF signaling pathway
rno04714
Thermogenesis
rno04750
Inflammatory mediator regulation of TRP channels
rno04912
GnRH signaling pathway
rno04935
Growth hormone synthesis, secretion and action
rno04936
Alcoholic liver disease
rno05014
Amyotrophic lateral sclerosis
rno05022
Pathways of neurodegeneration - multiple diseases
rno05132
Salmonella infection
rno05135
Yersinia infection
rno05145
Toxoplasmosis
rno05161
Hepatitis B
rno05169
Epstein-Barr virus infection
rno05170
Human immunodeficiency virus 1 infection
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
303200 (Map2k3)
04015 Rap1 signaling pathway
303200 (Map2k3)
04668 TNF signaling pathway
303200 (Map2k3)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
303200 (Map2k3)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
303200 (Map2k3)
04664 Fc epsilon RI signaling pathway
303200 (Map2k3)
09152 Endocrine system
04912 GnRH signaling pathway
303200 (Map2k3)
04935 Growth hormone synthesis, secretion and action
303200 (Map2k3)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
303200 (Map2k3)
09159 Environmental adaptation
04714 Thermogenesis
303200 (Map2k3)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
303200 (Map2k3)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
303200 (Map2k3)
05161 Hepatitis B
303200 (Map2k3)
05169 Epstein-Barr virus infection
303200 (Map2k3)
09171 Infectious disease: bacterial
05132 Salmonella infection
303200 (Map2k3)
05135 Yersinia infection
303200 (Map2k3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
303200 (Map2k3)
09164 Neurodegenerative disease
05014 Amyotrophic lateral sclerosis
303200 (Map2k3)
05022 Pathways of neurodegeneration - multiple diseases
303200 (Map2k3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
303200 (Map2k3)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
303200 (Map2k3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
303200 (Map2k3)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.12 Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
2.7.12.2 mitogen-activated protein kinase kinase
303200 (Map2k3)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: STE group
STE7 family
303200 (Map2k3)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Kinase-like
ABC1
Seadorna_VP7
Pkinase_fungal
Haspin_kinase
APH
Choline_kinase
RIO1
DUF4344
Motif
Other DBs
NCBI-GeneID:
303200
NCBI-ProteinID:
NP_001094144
RGD:
1306620
Ensembl:
ENSRNOG00000049132
UniProt:
B1H230
Q498S1
LinkDB
All DBs
Position
10:45608145..45629492
Genome browser
AA seq
347 aa
AA seq
DB search
MESPAASPPASLPQTKGKSKRKRDLRISCVSKPPVSNPTPPRNLDSRTFITIGDRNFEVE
ADDLVTISELGRGAYGVVEKVRHAQSGTIMAVKRIRATVNSQEQKRLLMDLDINMRTVDC
FYTVTFYGALFREGDVWICMELMDTSLDKFYRKVLEKNMKIPEDILGEIAVSIVRALEHL
HSKLSVIHRDVKPSNVLINKEGHVKMCDFGISGYLVDSVAKTMDAGCKPYMAPERINPEL
NQKGYNVKSDVWSLGITMIEMAILRFPYESWGTPFQQLKQVVEEPSPQLPADQFSPEFVD
FTSQCLRKNPAERMSYLELMEHPFFTLHKTKKTDIAAFVKEILGEDS
NT seq
1044 nt
NT seq
+upstream
nt +downstream
nt
atggagtcgcccgccgccagcccgccggccagcttgcctcagaccaaaggaaaatccaaa
aggaaaagggatttacggatatcctgtgtgtccaagccacccgtgtccaaccccacaccc
ccccggaacctggactcccggaccttcatcactatcggagacagaaacttcgaagtggag
gctgatgacttggtgaccatctcagagctgggccgcggagcctatggggtggtggagaag
gtgcggcatgctcagagtggtaccatcatggctgtcaagcgcatccgggccactgtgaac
tcacaggagcagaaacgtctgcttatggacctagacatcaacatgcgcactgtcgactgc
ttctatactgtcaccttctatggtgccctctttagagagggggatgtgtggatctgcatg
gaactcatggacacgtccctggataagttctaccggaaggtgctagagaagaacatgaaa
attccggaagacattctgggggagattgctgtatccatcgtgcgggccctggagcaccta
cacagcaagctgtctgtgatccacagagatgtgaagccttccaatgtcctcatcaacaaa
gaggggcacgtgaagatgtgcgactttggcatcagtggctacctggtggactctgtggca
aagacaatggatgctggctgcaagccttacatggcccctgagaggatcaaccctgagctg
aatcagaagggctacaacgtcaagtctgatgtctggagccttggcatcaccatgattgag
atggccattctgcgattcccttacgagtcttgggggacaccgttccagcagctgaagcag
gtggtggaggagccatccccacagctcccagcagaccagttctcccctgagtttgtggac
ttcacaagccagtgcctcaggaagaatcctgcggaacgcatgagctacctggagctgatg
gaacacccgttcttcaccttgcacaaaactaagaagacggacattgctgcctttgtgaag
gagatcctgggagaggattcatag
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integrated database retrieval system
