KEGG   Rattus norvegicus (rat): 170538
Entry
170538            CDS       T01003                                 

Gene name
Prkcd
Definition
(RefSeq) protein kinase C delta type
  KO
K06068  novel protein kinase C delta type [EC:2.7.11.13]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04062  Chemokine signaling pathway
rno04140  Autophagy - animal
rno04270  Vascular smooth muscle contraction
rno04621  NOD-like receptor signaling pathway
rno04625  C-type lectin receptor signaling pathway
rno04666  Fc gamma R-mediated phagocytosis
rno04722  Neurotrophin signaling pathway
rno04750  Inflammatory mediator regulation of TRP channels
rno04912  GnRH signaling pathway
rno04915  Estrogen signaling pathway
rno04930  Type II diabetes mellitus
rno04931  Insulin resistance
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno05020  Prion disease
rno05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    170538 (Prkcd)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    170538 (Prkcd)
   04625 C-type lectin receptor signaling pathway
    170538 (Prkcd)
   04666 Fc gamma R-mediated phagocytosis
    170538 (Prkcd)
   04062 Chemokine signaling pathway
    170538 (Prkcd)
  09152 Endocrine system
   04912 GnRH signaling pathway
    170538 (Prkcd)
   04915 Estrogen signaling pathway
    170538 (Prkcd)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    170538 (Prkcd)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    170538 (Prkcd)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    170538 (Prkcd)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05020 Prion disease
    170538 (Prkcd)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    170538 (Prkcd)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    170538 (Prkcd)
   04931 Insulin resistance
    170538 (Prkcd)
   04933 AGE-RAGE signaling pathway in diabetic complications
    170538 (Prkcd)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    170538 (Prkcd)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     170538 (Prkcd)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   170538 (Prkcd)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 Pkinase_C C1_2 zf-RING-like Zf_RING zf-RING_9 DZR Kinase-like ABC1 Pkinase_fungal PHD FtrD-like APH CxC3 FYVE_2
Other DBs
NCBI-GeneID: 170538
NCBI-ProteinID: NP_579841
RGD: 67383
Ensembl: ENSRNOG00000016346
UniProt: P09215
LinkDB
Structure
PDB: 
1BDY

Position
16
AA seq 673 aa
MAPFLRISFNSYELGSLQAEDDASQPFCAVKMKEALTTDRGKTLVQKKPTMYPEWKSTFD
AHIYEGRVIQIVLMRAAEDPMSEVTVGVSVLAERCKKNNGKAEFWLDLQPQAKVLMCVQY
FLEDGDCKQSMRSEEEAMFPTMNRRGAIKQAKIHYIKNHEFIATFFGQPTFCSVCKEFVW
GLNKQGYKCRQCNAAIHKKCIDKIIGRCTGTATNSRDTIFQKERFNIDMPHRFKVYNYMS
PTFCDHCGTLLWGLVKQGLKCEDCGMNVHHKCREKVANLCGINQKLLAEALNQVTQKASR
KPETPETVGIYQGFEKKTAVSGNDIPDNNGTYGKIWEGSNRCRLENFTFQKVLGKGSFGK
VLLAELKGKERYFAIKYLKKDVVLIDDDVECTMVEKRVLALAWENPFLTHLICTFQTKDH
LFFVMEFLNGGDLMFHIQDKGRFELYRATFYAAEIICGLQFLHGKGIIYRDLKLDNVMLD
KDGHIKIADFGMCKENIFGENRASTFCGTPDYIAPEILQGLKYSFSVDWWSFGVLLYEML
IGQSPFHGDDEDELFESIRVDTPHYPRWITKESKDIMEKLFERDPAKRLGVTGNIRLHPF
FKTINWNLLEKRKVEPPFKPKVKSPSDYSNFDPEFLNEKPQLSFSDKNLIDSMDQTAFKG
FSFVNPKYEQFLE
NT seq 2022 nt   +upstreamnt  +downstreamnt
atggcaccgttcctgcgcatctccttcaattcctatgagctgggctccctgcaggcggag
gacgacgcaagccagcctttctgtgccgtgaagatgaaggaggcactcaccacagaccga
gggaagactctggtacagaagaagcccaccatgtaccctgagtggaagtcaacattcgac
gcccacatctatgaaggccgtgtcatccagatcgtgctgatgcgggcagctgaagacccc
atgtcggaggtgaccgtgggcgtgtcagtgctggctgagcgctgcaagaagaacaacggc
aaggctgagttctggctggacctgcagcctcaggccaaggtgctgatgtgtgtgcagtat
ttcctggaggatggggattgcaaacagtccatgcgtagtgaggaggaggccatgttccca
actatgaaccgccgtggagccattaaacaggccaagattcactacatcaagaaccacgag
ttcatcgccaccttctttgggcagcccaccttctgttctgtgtgcaaagagtttgtctgg
ggcctcaacaagcaaggctacaaatgcaggcaatgcaacgctgccatccataagaaatgc
atcgacaagattatcggccgctgcactggcactgctaccaatagccgggacaccatcttc
cagaaagaacgcttcaacatcgacatgcctcaccgattcaaggtctataactacatgagc
cccaccttctgtgaccactgtggcactttgctctggggattggtgaaacagggattaaag
tgtgaagactgcggcatgaatgtgcaccacaaatgccgggagaaggtggccaacctgtgt
ggtatcaaccaaaagctcttggctgaggccttgaaccaagtgacccagaaagcttcccgg
aagccagagacaccagagactgtcggaatataccagggattcgagaagaagacagctgtc
tctgggaatgacatcccagacaacaacgggacctatggcaagatctgggaggggagcaac
cggtgccgccttgagaacttcaccttccagaaagtacttggcaaaggcagctttggcaag
gtactgcttgcagaactgaagggcaaggaaaggtactttgcaatcaagtacctgaagaag
gacgtggtgttgatcgacgatgacgtggagtgcaccatggtggagaagcgggtgctggcg
ctcgcctgggagaatcccttcctcacccatctcatctgtaccttccagaccaaggaccac
ctcttctttgtgatggagttcctcaatgggggcgatctgatgttccacattcaggacaaa
ggccgcttcgaactctaccgggctacgttttatgcagctgagatcatctgcggactgcag
tttctacatggcaaaggcatcatttacagggacctcaagctagacaatgtaatgctggac
aaggatggccacatcaagattgctgacttcgggatgtgcaaagagaatatatttggggag
aaccgggccagcacattctgcggcactcctgactacatcgcccctgagatcctgcagggc
ctgaagtactcattttccgtggactggtggtcttttggggtcctcctctatgagatgctc
attggccagtcccccttccatggtgatgatgaggacgagctctttgagtccatccgggtg
gacacaccacactacccgcgctggatcaccaaggagtccaaggacatcatggagaagctc
ttcgagagggaccctgccaagaggctgggagtaacaggaaacatcaggcttcaccccttt
ttcaagactatcaactggaacctgctggagaagcggaaggtggagccgccctttaagccc
aaagtgaaatccccttcagactacagcaactttgacccagagttcctgaatgagaaaccc
caactttccttcagtgacaagaacctcatcgactctatggaccagacagccttcaagggc
ttctcctttgtgaaccccaaatatgagcaattcctggaatag

KEGG   Rattus norvegicus (rat): 29340
Entry
29340             CDS       T01003                                 

Gene name
Prkce
Definition
(RefSeq) protein kinase C epsilon type
  KO
K18050  novel protein kinase C epsilon type [EC:2.7.11.13]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04022  cGMP-PKG signaling pathway
rno04071  Sphingolipid signaling pathway
rno04270  Vascular smooth muscle contraction
rno04371  Apelin signaling pathway
rno04530  Tight junction
rno04666  Fc gamma R-mediated phagocytosis
rno04750  Inflammatory mediator regulation of TRP channels
rno04925  Aldosterone synthesis and secretion
rno04930  Type II diabetes mellitus
rno04931  Insulin resistance
rno04933  AGE-RAGE signaling pathway in diabetic complications
rno05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04371 Apelin signaling pathway
    29340 (Prkce)
   04071 Sphingolipid signaling pathway
    29340 (Prkce)
   04022 cGMP-PKG signaling pathway
    29340 (Prkce)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    29340 (Prkce)
 09150 Organismal Systems
  09151 Immune system
   04666 Fc gamma R-mediated phagocytosis
    29340 (Prkce)
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    29340 (Prkce)
  09153 Circulatory system
   04270 Vascular smooth muscle contraction
    29340 (Prkce)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    29340 (Prkce)
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    29340 (Prkce)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    29340 (Prkce)
   04931 Insulin resistance
    29340 (Prkce)
   04933 AGE-RAGE signaling pathway in diabetic complications
    29340 (Prkce)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:rno01001]
    29340 (Prkce)
Enzymes [BR:rno01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.13  protein kinase C
     29340 (Prkce)
Protein kinases [BR:rno01001]
 Serine/threonine kinases: AGC group
  PKC family [OT]
   29340 (Prkce)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C ABC1 FTA2 Kinase-like Kdo PP_M1
Other DBs
NCBI-GeneID: 29340
NCBI-ProteinID: NP_058867
RGD: 61925
UniProt: P09216 Q6DUV1
LinkDB
Position
6
AA seq 737 aa
MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKT
NSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLE
PEGKVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQP
TYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQETPDEVGSQRFSVN
MPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIA
KVLADLGVTPDKITNSGQRRKKLAAGAESPQPASGNSPSEDDRSKSAPTSPCDQELKELE
NNIRKALSFDNRGEEHRASSSTDGQLASPGENGEVRQGQAKRLGLDEFNFIKVLGKGSFG
KVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKD
RLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILL
DAEGHCKLADFGMCKEGILNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEM
MAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVAAQNGED
AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPILTLVDEAIVKQI
NQEEFKGFSYFGEDLMP
NT seq 2214 nt   +upstreamnt  +downstreamnt
atggtagtgttcaatggccttcttaagatcaaaatctgcgaggccgtgagcttgaagccc
acagcctggtcgctgcgccatgcggtgggaccccggccccagacgttccttctggacccc
tacattgcccttaacgtggacgactcgcgcatcggccaaacagccaccaagcagaagacc
aacagtccggcctggcacgatgagttcgtcactgatgtgtgcaatgggcgcaagatcgag
ctggctgtctttcacgatgctcctatcggctacgacgacttcgtggccaactgcaccatc
cagttcgaggagctgctgcagaatgggagccgtcacttcgaggactggattgatctggag
ccagaaggaaaagtctacgtgatcatcgatctctcgggatcatcgggcgaagcccctaaa
gacaatgaagaacgagtgtttagggagcggatgcggccaaggaagcgccaaggggctgtc
aggcgcagggtccaccaggtcaatggccacaagttcatggccacctacttgcggcagccc
acctactgctcccactgtagggatttcatctggggtgtcataggaaaacagggatatcaa
tgtcaagtttgtacctgcgtcgtccacaaacgatgccatgagctcattattacgaagtgc
gctgggctaaagaaacaggaaacccctgacgaggtgggctcccaacgcttcagcgtcaac
atgccccacaagttcgggatccacaactacaaggtccccacgttctgtgaccactgtggc
tccctgctctggggcctcttgcggcagggcctgcagtgtaaagtctgcaaaatgaatgtt
caccgtcgatgcgagaccaacgtggctcccaattgtggggtggacgccagaggaattgcc
aaggtgctggccgatcttggcgttactccagacaaaatcaccaacagtggccagagaagg
aaaaagctcgctgctggtgctgagtccccacagccggcttctggaaactccccatcagaa
gacgaccgatccaagtcagcgcccacctccccttgtgaccaggaactaaaagaacttgaa
aacaacatccggaaggccttgtcatttgacaaccgaggagaggagcaccgagcctcgtcg
tctactgatggccagctggcaagccctggcgagaacggtgaagtccggcaaggccaggcc
aagcgcttgggcctggatgagttcaacttcatcaaggtgttaggcaaaggcagctttggc
aaggtcatgctggccgagctcaagggtaaggatgaagtctatgctgtgaaggtcttaaag
aaggacgtcatcctgcaggatgacgacgtggactgcacgatgacagagaagaggattttg
gctctggcgcggaaacacccttatctaacccaactctattgctgcttccagaccaaggac
cgcctcttcttcgtcatggaatatgtaaacggtggagacctcatgttccagattcagcgg
tcccgaaaattcgatgagcctcgttcccggttctatgctgccgaggtcacatctgctctc
atgtttctccaccaacatggagtgatctacagggatttgaaactggacaacatccttcta
gatgcagaaggtcactgcaagctggctgactttgggatgtgcaaggaagggattctgaat
ggcgtgacaactaccaccttctgtgggactcctgactacatagctccagagatcctgcag
gagttggagtacggcccctcagtggactggtgggccctgggcgtgctgatgtacgagatg
atggccgggcagcccccctttgaagctgacaacgaggacgacttgtttgaatccatcctt
cacgatgacgttctctaccctgtctggcttagcaaggaggctgtcagcatcctgaaagct
ttcatgaccaagaacccgcacaagcgcctgggctgcgtggcagcacagaacggggaagat
gccatcaagcaacatccattcttcaaggagattgactgggtactgctggagcagaagaaa
atcaagccccccttcaagccgagaattaaaaccaagagagatgtcaataactttgaccaa
gactttacccgggaagagccaatacttacacttgtggatgaagcaatcgtgaagcagatc
aaccaggaagaattcaaaggcttctcctactttggtgaagacctgatgccctga

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