Rattus norvegicus (rat): 24185
Help
Entry
24185 CDS
T01003
Gene name
Akt1
Definition
(RefSeq) RAC-alpha serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno01522
Endocrine resistance
rno01524
Platinum drug resistance
rno04010
MAPK signaling pathway
rno04012
ErbB signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04062
Chemokine signaling pathway
rno04066
HIF-1 signaling pathway
rno04068
FoxO signaling pathway
rno04071
Sphingolipid signaling pathway
rno04072
Phospholipase D signaling pathway
rno04140
Autophagy - animal
rno04150
mTOR signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04152
AMPK signaling pathway
rno04210
Apoptosis
rno04211
Longevity regulating pathway
rno04213
Longevity regulating pathway - multiple species
rno04218
Cellular senescence
rno04261
Adrenergic signaling in cardiomyocytes
rno04370
VEGF signaling pathway
rno04371
Apelin signaling pathway
rno04380
Osteoclast differentiation
rno04510
Focal adhesion
rno04550
Signaling pathways regulating pluripotency of stem cells
rno04611
Platelet activation
rno04613
Neutrophil extracellular trap formation
rno04620
Toll-like receptor signaling pathway
rno04625
C-type lectin receptor signaling pathway
rno04630
JAK-STAT signaling pathway
rno04660
T cell receptor signaling pathway
rno04662
B cell receptor signaling pathway
rno04664
Fc epsilon RI signaling pathway
rno04666
Fc gamma R-mediated phagocytosis
rno04668
TNF signaling pathway
rno04722
Neurotrophin signaling pathway
rno04725
Cholinergic synapse
rno04728
Dopaminergic synapse
rno04910
Insulin signaling pathway
rno04914
Progesterone-mediated oocyte maturation
rno04915
Estrogen signaling pathway
rno04917
Prolactin signaling pathway
rno04919
Thyroid hormone signaling pathway
rno04920
Adipocytokine signaling pathway
rno04922
Glucagon signaling pathway
rno04923
Regulation of lipolysis in adipocytes
rno04926
Relaxin signaling pathway
rno04929
GnRH secretion
rno04931
Insulin resistance
rno04932
Non-alcoholic fatty liver disease
rno04933
AGE-RAGE signaling pathway in diabetic complications
rno04935
Growth hormone synthesis, secretion and action
rno04973
Carbohydrate digestion and absorption
rno05010
Alzheimer disease
rno05017
Spinocerebellar ataxia
rno05132
Salmonella infection
rno05135
Yersinia infection
rno05142
Chagas disease
rno05145
Toxoplasmosis
rno05152
Tuberculosis
rno05160
Hepatitis C
rno05161
Hepatitis B
rno05162
Measles
rno05163
Human cytomegalovirus infection
rno05164
Influenza A
rno05165
Human papillomavirus infection
rno05166
Human T-cell leukemia virus 1 infection
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05168
Herpes simplex virus 1 infection
rno05169
Epstein-Barr virus infection
rno05170
Human immunodeficiency virus 1 infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05210
Colorectal cancer
rno05211
Renal cell carcinoma
rno05212
Pancreatic cancer
rno05213
Endometrial cancer
rno05214
Glioma
rno05215
Prostate cancer
rno05218
Melanoma
rno05220
Chronic myeloid leukemia
rno05221
Acute myeloid leukemia
rno05222
Small cell lung cancer
rno05223
Non-small cell lung cancer
rno05224
Breast cancer
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
rno05230
Central carbon metabolism in cancer
rno05231
Choline metabolism in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05415
Diabetic cardiomyopathy
rno05417
Lipid and atherosclerosis
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
24185 (Akt1)
04012 ErbB signaling pathway
24185 (Akt1)
04014 Ras signaling pathway
24185 (Akt1)
04015 Rap1 signaling pathway
24185 (Akt1)
04370 VEGF signaling pathway
24185 (Akt1)
04371 Apelin signaling pathway
24185 (Akt1)
04630 JAK-STAT signaling pathway
24185 (Akt1)
04668 TNF signaling pathway
24185 (Akt1)
04066 HIF-1 signaling pathway
24185 (Akt1)
04068 FoxO signaling pathway
24185 (Akt1)
04072 Phospholipase D signaling pathway
24185 (Akt1)
04071 Sphingolipid signaling pathway
24185 (Akt1)
04024 cAMP signaling pathway
24185 (Akt1)
04022 cGMP-PKG signaling pathway
24185 (Akt1)
04151 PI3K-Akt signaling pathway
24185 (Akt1)
04152 AMPK signaling pathway
24185 (Akt1)
04150 mTOR signaling pathway
24185 (Akt1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
24185 (Akt1)
09143 Cell growth and death
04210 Apoptosis
24185 (Akt1)
04218 Cellular senescence
24185 (Akt1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
24185 (Akt1)
04550 Signaling pathways regulating pluripotency of stem cells
24185 (Akt1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
24185 (Akt1)
04613 Neutrophil extracellular trap formation
24185 (Akt1)
04620 Toll-like receptor signaling pathway
24185 (Akt1)
04625 C-type lectin receptor signaling pathway
24185 (Akt1)
04660 T cell receptor signaling pathway
24185 (Akt1)
04662 B cell receptor signaling pathway
24185 (Akt1)
04664 Fc epsilon RI signaling pathway
24185 (Akt1)
04666 Fc gamma R-mediated phagocytosis
24185 (Akt1)
04062 Chemokine signaling pathway
24185 (Akt1)
09152 Endocrine system
04910 Insulin signaling pathway
24185 (Akt1)
04922 Glucagon signaling pathway
24185 (Akt1)
04923 Regulation of lipolysis in adipocytes
24185 (Akt1)
04920 Adipocytokine signaling pathway
24185 (Akt1)
04929 GnRH secretion
24185 (Akt1)
04915 Estrogen signaling pathway
24185 (Akt1)
04914 Progesterone-mediated oocyte maturation
24185 (Akt1)
04917 Prolactin signaling pathway
24185 (Akt1)
04926 Relaxin signaling pathway
24185 (Akt1)
04935 Growth hormone synthesis, secretion and action
24185 (Akt1)
04919 Thyroid hormone signaling pathway
24185 (Akt1)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
24185 (Akt1)
09154 Digestive system
04973 Carbohydrate digestion and absorption
24185 (Akt1)
09156 Nervous system
04725 Cholinergic synapse
24185 (Akt1)
04728 Dopaminergic synapse
24185 (Akt1)
04722 Neurotrophin signaling pathway
24185 (Akt1)
09158 Development and regeneration
04380 Osteoclast differentiation
24185 (Akt1)
09149 Aging
04211 Longevity regulating pathway
24185 (Akt1)
04213 Longevity regulating pathway - multiple species
24185 (Akt1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
24185 (Akt1)
05205 Proteoglycans in cancer
24185 (Akt1)
05230 Central carbon metabolism in cancer
24185 (Akt1)
05231 Choline metabolism in cancer
24185 (Akt1)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
24185 (Akt1)
09162 Cancer: specific types
05210 Colorectal cancer
24185 (Akt1)
05212 Pancreatic cancer
24185 (Akt1)
05225 Hepatocellular carcinoma
24185 (Akt1)
05226 Gastric cancer
24185 (Akt1)
05214 Glioma
24185 (Akt1)
05221 Acute myeloid leukemia
24185 (Akt1)
05220 Chronic myeloid leukemia
24185 (Akt1)
05218 Melanoma
24185 (Akt1)
05211 Renal cell carcinoma
24185 (Akt1)
05215 Prostate cancer
24185 (Akt1)
05213 Endometrial cancer
24185 (Akt1)
05224 Breast cancer
24185 (Akt1)
05222 Small cell lung cancer
24185 (Akt1)
05223 Non-small cell lung cancer
24185 (Akt1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
24185 (Akt1)
05170 Human immunodeficiency virus 1 infection
24185 (Akt1)
05161 Hepatitis B
24185 (Akt1)
05160 Hepatitis C
24185 (Akt1)
05164 Influenza A
24185 (Akt1)
05162 Measles
24185 (Akt1)
05168 Herpes simplex virus 1 infection
24185 (Akt1)
05163 Human cytomegalovirus infection
24185 (Akt1)
05167 Kaposi sarcoma-associated herpesvirus infection
24185 (Akt1)
05169 Epstein-Barr virus infection
24185 (Akt1)
05165 Human papillomavirus infection
24185 (Akt1)
09171 Infectious disease: bacterial
05132 Salmonella infection
24185 (Akt1)
05135 Yersinia infection
24185 (Akt1)
05152 Tuberculosis
24185 (Akt1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
24185 (Akt1)
05142 Chagas disease
24185 (Akt1)
09164 Neurodegenerative disease
05010 Alzheimer disease
24185 (Akt1)
05017 Spinocerebellar ataxia
24185 (Akt1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
24185 (Akt1)
05418 Fluid shear stress and atherosclerosis
24185 (Akt1)
05415 Diabetic cardiomyopathy
24185 (Akt1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
24185 (Akt1)
04931 Insulin resistance
24185 (Akt1)
04933 AGE-RAGE signaling pathway in diabetic complications
24185 (Akt1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
24185 (Akt1)
01524 Platinum drug resistance
24185 (Akt1)
01522 Endocrine resistance
24185 (Akt1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
24185 (Akt1)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
24185 (Akt1)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
24185 (Akt1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Pkinase_C
Kinase-like
PH_11
Seadorna_VP7
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
24185
NCBI-ProteinID:
NP_150233
RGD:
2081
Ensembl:
ENSRNOG00000028629
UniProt:
P47196
LinkDB
All DBs
Position
6
AA seq
480 aa
AA seq
DB search
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAQC
QLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKRQEEETMDF
RSGSPSDNSGAEEMEVALAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKATGRYYAMKI
LKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANGGELFFHLS
RERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITDFGLCKEGI
KDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFEL
ILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIVWQDVYEKK
LSPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQFSYSASGTA
NT seq
1443 nt
NT seq
+upstream
nt +downstream
nt
atgaacgacgtagccattgtgaaggagggctggctgcacaaacgaggggaatatattaaa
acctggcggccacgctacttcctcctcaagaatgatggcacctttattggctacaaggaa
cggcctcaggatgtggagcagcgcgagtccccactcaacaacttctcagtggcacaatgt
cagctgatgaagacagagcggccgaggcccaacaccttcatcatccgctgcctgcagtgg
accacggtcattgagcgcaccttccatgtggaaacgcctgaggagcgggaagagtggacc
accgccattcagactgtggctgatggactcaaacggcaggaggaggagacgatggacttc
cggtcaggttcacccagtgacaactcaggtgctgaggagatggaggtggccctggccaag
cccaagcaccgtgtgaccatgaacgagtttgagtacctgaagctactgggcaagggcacc
tttgggaaggtgatcctggtgaaggagaaggccacaggtcgctactatgccatgaagatc
ctcaagaaggaggtcatcgttgccaaggatgaggttgcccacacgcttactgagaaccgt
gtcctgcagaactctaggcatcccttccttacagccctcaagtactcattccagacccac
gaccgcctctgctttgtcatggagtacgccaatgggggcgagctcttcttccacctgtct
cgtgagcgcgtgttttcagaggaccgggcccgcttctacggtgcggagattgtgtccgcc
ctggactacttgcactccgagaagaacgtggtgtaccgggacctcaagctggagaacctc
atgctggacaaggacgggcacatcaagataacggacttcgggctgtgcaaggagggtatc
aaggacggtgccaccatgaagacgttctgcgggacacccgagtacctggcccctgaggtg
ctggaggacaacgactatggccgtgcagtggactggtgggggctgggcgtggtcatgtac
gagatgatgtgcggccgcctgcccttctacaaccaggaccatgagaagctgttcgagctc
atcctaatggaggagatccgcttcccacgcacactcgggccggaggccaagtccctgctc
tcggggctgctcaagaaggaccctacacagaggctcggtgggggctccgaggacgccaag
gagatcatgcagcaccgcttctttgccaacatcgtgtggcaagatgtgtatgagaagaag
ctgagcccacctttcaagccccaggtcacctctgagaccgacaccaggtattttgatgag
gagttcacagctcagatgatcaccatcacgccgcctgatcaagatgacagcatggagtgt
gtggacagtgaacggaggccgcactttccccagttctcctactcagccagtggcacagcc
tga
Rattus norvegicus (rat): 25233
Help
Entry
25233 CDS
T01003
Gene name
Akt2
Definition
(RefSeq) RAC-beta serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno01522
Endocrine resistance
rno01524
Platinum drug resistance
rno04010
MAPK signaling pathway
rno04012
ErbB signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04062
Chemokine signaling pathway
rno04066
HIF-1 signaling pathway
rno04068
FoxO signaling pathway
rno04071
Sphingolipid signaling pathway
rno04072
Phospholipase D signaling pathway
rno04140
Autophagy - animal
rno04150
mTOR signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04152
AMPK signaling pathway
rno04210
Apoptosis
rno04211
Longevity regulating pathway
rno04213
Longevity regulating pathway - multiple species
rno04218
Cellular senescence
rno04261
Adrenergic signaling in cardiomyocytes
rno04370
VEGF signaling pathway
rno04371
Apelin signaling pathway
rno04380
Osteoclast differentiation
rno04510
Focal adhesion
rno04550
Signaling pathways regulating pluripotency of stem cells
rno04611
Platelet activation
rno04613
Neutrophil extracellular trap formation
rno04620
Toll-like receptor signaling pathway
rno04625
C-type lectin receptor signaling pathway
rno04630
JAK-STAT signaling pathway
rno04660
T cell receptor signaling pathway
rno04662
B cell receptor signaling pathway
rno04664
Fc epsilon RI signaling pathway
rno04666
Fc gamma R-mediated phagocytosis
rno04668
TNF signaling pathway
rno04722
Neurotrophin signaling pathway
rno04725
Cholinergic synapse
rno04728
Dopaminergic synapse
rno04910
Insulin signaling pathway
rno04914
Progesterone-mediated oocyte maturation
rno04915
Estrogen signaling pathway
rno04917
Prolactin signaling pathway
rno04919
Thyroid hormone signaling pathway
rno04920
Adipocytokine signaling pathway
rno04922
Glucagon signaling pathway
rno04923
Regulation of lipolysis in adipocytes
rno04926
Relaxin signaling pathway
rno04929
GnRH secretion
rno04931
Insulin resistance
rno04932
Non-alcoholic fatty liver disease
rno04933
AGE-RAGE signaling pathway in diabetic complications
rno04935
Growth hormone synthesis, secretion and action
rno04973
Carbohydrate digestion and absorption
rno05010
Alzheimer disease
rno05017
Spinocerebellar ataxia
rno05132
Salmonella infection
rno05135
Yersinia infection
rno05142
Chagas disease
rno05145
Toxoplasmosis
rno05152
Tuberculosis
rno05160
Hepatitis C
rno05161
Hepatitis B
rno05162
Measles
rno05163
Human cytomegalovirus infection
rno05164
Influenza A
rno05165
Human papillomavirus infection
rno05166
Human T-cell leukemia virus 1 infection
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05168
Herpes simplex virus 1 infection
rno05169
Epstein-Barr virus infection
rno05170
Human immunodeficiency virus 1 infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05210
Colorectal cancer
rno05211
Renal cell carcinoma
rno05212
Pancreatic cancer
rno05213
Endometrial cancer
rno05214
Glioma
rno05215
Prostate cancer
rno05218
Melanoma
rno05220
Chronic myeloid leukemia
rno05221
Acute myeloid leukemia
rno05222
Small cell lung cancer
rno05223
Non-small cell lung cancer
rno05224
Breast cancer
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
rno05230
Central carbon metabolism in cancer
rno05231
Choline metabolism in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05415
Diabetic cardiomyopathy
rno05417
Lipid and atherosclerosis
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
25233 (Akt2)
04012 ErbB signaling pathway
25233 (Akt2)
04014 Ras signaling pathway
25233 (Akt2)
04015 Rap1 signaling pathway
25233 (Akt2)
04370 VEGF signaling pathway
25233 (Akt2)
04371 Apelin signaling pathway
25233 (Akt2)
04630 JAK-STAT signaling pathway
25233 (Akt2)
04668 TNF signaling pathway
25233 (Akt2)
04066 HIF-1 signaling pathway
25233 (Akt2)
04068 FoxO signaling pathway
25233 (Akt2)
04072 Phospholipase D signaling pathway
25233 (Akt2)
04071 Sphingolipid signaling pathway
25233 (Akt2)
04024 cAMP signaling pathway
25233 (Akt2)
04022 cGMP-PKG signaling pathway
25233 (Akt2)
04151 PI3K-Akt signaling pathway
25233 (Akt2)
04152 AMPK signaling pathway
25233 (Akt2)
04150 mTOR signaling pathway
25233 (Akt2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
25233 (Akt2)
09143 Cell growth and death
04210 Apoptosis
25233 (Akt2)
04218 Cellular senescence
25233 (Akt2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
25233 (Akt2)
04550 Signaling pathways regulating pluripotency of stem cells
25233 (Akt2)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
25233 (Akt2)
04613 Neutrophil extracellular trap formation
25233 (Akt2)
04620 Toll-like receptor signaling pathway
25233 (Akt2)
04625 C-type lectin receptor signaling pathway
25233 (Akt2)
04660 T cell receptor signaling pathway
25233 (Akt2)
04662 B cell receptor signaling pathway
25233 (Akt2)
04664 Fc epsilon RI signaling pathway
25233 (Akt2)
04666 Fc gamma R-mediated phagocytosis
25233 (Akt2)
04062 Chemokine signaling pathway
25233 (Akt2)
09152 Endocrine system
04910 Insulin signaling pathway
25233 (Akt2)
04922 Glucagon signaling pathway
25233 (Akt2)
04923 Regulation of lipolysis in adipocytes
25233 (Akt2)
04920 Adipocytokine signaling pathway
25233 (Akt2)
04929 GnRH secretion
25233 (Akt2)
04915 Estrogen signaling pathway
25233 (Akt2)
04914 Progesterone-mediated oocyte maturation
25233 (Akt2)
04917 Prolactin signaling pathway
25233 (Akt2)
04926 Relaxin signaling pathway
25233 (Akt2)
04935 Growth hormone synthesis, secretion and action
25233 (Akt2)
04919 Thyroid hormone signaling pathway
25233 (Akt2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
25233 (Akt2)
09154 Digestive system
04973 Carbohydrate digestion and absorption
25233 (Akt2)
09156 Nervous system
04725 Cholinergic synapse
25233 (Akt2)
04728 Dopaminergic synapse
25233 (Akt2)
04722 Neurotrophin signaling pathway
25233 (Akt2)
09158 Development and regeneration
04380 Osteoclast differentiation
25233 (Akt2)
09149 Aging
04211 Longevity regulating pathway
25233 (Akt2)
04213 Longevity regulating pathway - multiple species
25233 (Akt2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
25233 (Akt2)
05205 Proteoglycans in cancer
25233 (Akt2)
05230 Central carbon metabolism in cancer
25233 (Akt2)
05231 Choline metabolism in cancer
25233 (Akt2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
25233 (Akt2)
09162 Cancer: specific types
05210 Colorectal cancer
25233 (Akt2)
05212 Pancreatic cancer
25233 (Akt2)
05225 Hepatocellular carcinoma
25233 (Akt2)
05226 Gastric cancer
25233 (Akt2)
05214 Glioma
25233 (Akt2)
05221 Acute myeloid leukemia
25233 (Akt2)
05220 Chronic myeloid leukemia
25233 (Akt2)
05218 Melanoma
25233 (Akt2)
05211 Renal cell carcinoma
25233 (Akt2)
05215 Prostate cancer
25233 (Akt2)
05213 Endometrial cancer
25233 (Akt2)
05224 Breast cancer
25233 (Akt2)
05222 Small cell lung cancer
25233 (Akt2)
05223 Non-small cell lung cancer
25233 (Akt2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
25233 (Akt2)
05170 Human immunodeficiency virus 1 infection
25233 (Akt2)
05161 Hepatitis B
25233 (Akt2)
05160 Hepatitis C
25233 (Akt2)
05164 Influenza A
25233 (Akt2)
05162 Measles
25233 (Akt2)
05168 Herpes simplex virus 1 infection
25233 (Akt2)
05163 Human cytomegalovirus infection
25233 (Akt2)
05167 Kaposi sarcoma-associated herpesvirus infection
25233 (Akt2)
05169 Epstein-Barr virus infection
25233 (Akt2)
05165 Human papillomavirus infection
25233 (Akt2)
09171 Infectious disease: bacterial
05132 Salmonella infection
25233 (Akt2)
05135 Yersinia infection
25233 (Akt2)
05152 Tuberculosis
25233 (Akt2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
25233 (Akt2)
05142 Chagas disease
25233 (Akt2)
09164 Neurodegenerative disease
05010 Alzheimer disease
25233 (Akt2)
05017 Spinocerebellar ataxia
25233 (Akt2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
25233 (Akt2)
05418 Fluid shear stress and atherosclerosis
25233 (Akt2)
05415 Diabetic cardiomyopathy
25233 (Akt2)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
25233 (Akt2)
04931 Insulin resistance
25233 (Akt2)
04933 AGE-RAGE signaling pathway in diabetic complications
25233 (Akt2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
25233 (Akt2)
01524 Platinum drug resistance
25233 (Akt2)
01522 Endocrine resistance
25233 (Akt2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
25233 (Akt2)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
25233 (Akt2)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
25233 (Akt2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Kinase-like
Pkinase_C
PH_11
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
25233
NCBI-ProteinID:
NP_058789
RGD:
2082
Ensembl:
ENSRNOG00000018677
UniProt:
P47197
LinkDB
All DBs
Position
1
AA seq
481 aa
AA seq
DB search
MNEVSVIKEGWLHKRGEYIKTWRPRYFLLKSDGSFIGYKERPEAPDQTLPPLNNFSVAEC
QLMKTERPRPNTFVIRCLQWTTVIERTFHVDSPDEREEWIRAIQMVANSLKQRGPGEDAM
DYKCGSPSDSSTSEMMEVAVSKARAKVTMNDFDYLKLLGKGTFGKVILVREKATGRYYAM
KILRKEVIIAKDEVAHTVTESRVLQNTRHPFLTALKYAFQTHDRLCFVMEYANGGDLFFH
LSRERVFTEDRARFYGAEIVSALEYLHSTDVVYRDIKLENLMLDKDGHIKITDFGLSKEG
ISDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHERLFE
LILMEEIRFPRTLGPEAKSLLAGLLKKDPKQRLGGGPSDAKEVMEHRFFLSINWQDVVQK
KLLPPFKPQVTSEVDTRYFDDEFTAQSITITPPDRYDSLGSLELDQRTHFPQFSYSASIR
E
NT seq
1446 nt
NT seq
+upstream
nt +downstream
nt
atgaatgaggtatctgtcatcaaagaaggctggctccacaaacgtggtgaatacatcaag
acctggaggccccggtacttccttctgaagagtgatggatcttttattgggtataaagag
agacctgaggcccccgaccagaccctacccccccttaacaatttctctgtagcagaatgc
cagctgatgaagactgagaggccacgacccaacacctttgtcatacgctgcctgcagtgg
accacagtcatcgagaggaccttccatgtcgactctccagatgagagggaagagtggata
cgggctatccagatggtagccaacagtctgaagcagcggggccccggggaggatgccatg
gattacaagtgtggctcccccagtgactcttccacatctgagatgatggaggtagcggtc
agcaaggcacgggccaaagtgaccatgaacgacttcgattatctcaaactcctcggcaag
ggcaccttcggcaaagtcattctagttcgagagaaggccactggccgctattatgccatg
aagatcctgcggaaggaggtcatcattgcaaaggatgaagtcgcccacacagtcacagag
agccgagtcctacagaataccaggcaccccttccttacagccctgaagtatgccttccag
acccatgaccgcctgtgctttgtgatggagtatgccaacgggggcgacctgtttttccac
ctctctcgggagcgagtcttcacggaggatcgggcacgcttttatggtgcagagattgtg
tcagctctggagtacttgcactcgacggatgtggtgtaccgcgacatcaagctggaaaac
cttatgctggacaaagatggccacatcaagatcactgactttggcttgtccaaagagggc
atcagtgatggggccaccatgaaaaccttctgtggtaccccggagtacttggcgcctgag
gtgctagaggacaatgactacgggcgtgcagtggactggtggggactgggcgtggtcatg
tacgagatgatgtgcggccgcctgcccttctacaaccaggaccacgagcgcctcttcgag
ctcatcctcatggaggagatccggttcccacgcacgcttgggccagaggccaagtccctg
ctggctggactgctcaagaaggaccccaagcagaggctcggtgggggtcccagtgatgcc
aaggaggtcatggagcatcggttcttcctcagcatcaactggcaggatgtggtacagaag
aagctcctgccacccttcaaacctcaggtcacttcagaagtggacacaaggtactttgat
gatgaattcaccgcccagtccatcacaatcacacccccagaccgatatgacagcctgggc
tcgctggaactggaccagcgcacacacttcccccagttctcctactcagccagcatccga
gagtga
Rattus norvegicus (rat): 29414
Help
Entry
29414 CDS
T01003
Gene name
Akt3
Definition
(RefSeq) RAC-gamma serine/threonine-protein kinase
KO
K04456
RAC serine/threonine-protein kinase [EC:
2.7.11.1
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno01521
EGFR tyrosine kinase inhibitor resistance
rno01522
Endocrine resistance
rno01524
Platinum drug resistance
rno04010
MAPK signaling pathway
rno04012
ErbB signaling pathway
rno04014
Ras signaling pathway
rno04015
Rap1 signaling pathway
rno04022
cGMP-PKG signaling pathway
rno04024
cAMP signaling pathway
rno04062
Chemokine signaling pathway
rno04066
HIF-1 signaling pathway
rno04068
FoxO signaling pathway
rno04071
Sphingolipid signaling pathway
rno04072
Phospholipase D signaling pathway
rno04140
Autophagy - animal
rno04150
mTOR signaling pathway
rno04151
PI3K-Akt signaling pathway
rno04152
AMPK signaling pathway
rno04210
Apoptosis
rno04211
Longevity regulating pathway
rno04213
Longevity regulating pathway - multiple species
rno04218
Cellular senescence
rno04261
Adrenergic signaling in cardiomyocytes
rno04370
VEGF signaling pathway
rno04371
Apelin signaling pathway
rno04380
Osteoclast differentiation
rno04510
Focal adhesion
rno04550
Signaling pathways regulating pluripotency of stem cells
rno04611
Platelet activation
rno04613
Neutrophil extracellular trap formation
rno04620
Toll-like receptor signaling pathway
rno04625
C-type lectin receptor signaling pathway
rno04630
JAK-STAT signaling pathway
rno04660
T cell receptor signaling pathway
rno04662
B cell receptor signaling pathway
rno04664
Fc epsilon RI signaling pathway
rno04666
Fc gamma R-mediated phagocytosis
rno04668
TNF signaling pathway
rno04722
Neurotrophin signaling pathway
rno04725
Cholinergic synapse
rno04728
Dopaminergic synapse
rno04910
Insulin signaling pathway
rno04914
Progesterone-mediated oocyte maturation
rno04915
Estrogen signaling pathway
rno04917
Prolactin signaling pathway
rno04919
Thyroid hormone signaling pathway
rno04920
Adipocytokine signaling pathway
rno04922
Glucagon signaling pathway
rno04923
Regulation of lipolysis in adipocytes
rno04926
Relaxin signaling pathway
rno04929
GnRH secretion
rno04931
Insulin resistance
rno04932
Non-alcoholic fatty liver disease
rno04933
AGE-RAGE signaling pathway in diabetic complications
rno04935
Growth hormone synthesis, secretion and action
rno04973
Carbohydrate digestion and absorption
rno05010
Alzheimer disease
rno05017
Spinocerebellar ataxia
rno05132
Salmonella infection
rno05135
Yersinia infection
rno05142
Chagas disease
rno05145
Toxoplasmosis
rno05152
Tuberculosis
rno05160
Hepatitis C
rno05161
Hepatitis B
rno05162
Measles
rno05163
Human cytomegalovirus infection
rno05164
Influenza A
rno05165
Human papillomavirus infection
rno05166
Human T-cell leukemia virus 1 infection
rno05167
Kaposi sarcoma-associated herpesvirus infection
rno05168
Herpes simplex virus 1 infection
rno05169
Epstein-Barr virus infection
rno05170
Human immunodeficiency virus 1 infection
rno05200
Pathways in cancer
rno05205
Proteoglycans in cancer
rno05210
Colorectal cancer
rno05211
Renal cell carcinoma
rno05212
Pancreatic cancer
rno05213
Endometrial cancer
rno05214
Glioma
rno05215
Prostate cancer
rno05218
Melanoma
rno05220
Chronic myeloid leukemia
rno05221
Acute myeloid leukemia
rno05222
Small cell lung cancer
rno05223
Non-small cell lung cancer
rno05224
Breast cancer
rno05225
Hepatocellular carcinoma
rno05226
Gastric cancer
rno05230
Central carbon metabolism in cancer
rno05231
Choline metabolism in cancer
rno05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rno05415
Diabetic cardiomyopathy
rno05417
Lipid and atherosclerosis
rno05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
29414 (Akt3)
04012 ErbB signaling pathway
29414 (Akt3)
04014 Ras signaling pathway
29414 (Akt3)
04015 Rap1 signaling pathway
29414 (Akt3)
04370 VEGF signaling pathway
29414 (Akt3)
04371 Apelin signaling pathway
29414 (Akt3)
04630 JAK-STAT signaling pathway
29414 (Akt3)
04668 TNF signaling pathway
29414 (Akt3)
04066 HIF-1 signaling pathway
29414 (Akt3)
04068 FoxO signaling pathway
29414 (Akt3)
04072 Phospholipase D signaling pathway
29414 (Akt3)
04071 Sphingolipid signaling pathway
29414 (Akt3)
04024 cAMP signaling pathway
29414 (Akt3)
04022 cGMP-PKG signaling pathway
29414 (Akt3)
04151 PI3K-Akt signaling pathway
29414 (Akt3)
04152 AMPK signaling pathway
29414 (Akt3)
04150 mTOR signaling pathway
29414 (Akt3)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
29414 (Akt3)
09143 Cell growth and death
04210 Apoptosis
29414 (Akt3)
04218 Cellular senescence
29414 (Akt3)
09144 Cellular community - eukaryotes
04510 Focal adhesion
29414 (Akt3)
04550 Signaling pathways regulating pluripotency of stem cells
29414 (Akt3)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
29414 (Akt3)
04613 Neutrophil extracellular trap formation
29414 (Akt3)
04620 Toll-like receptor signaling pathway
29414 (Akt3)
04625 C-type lectin receptor signaling pathway
29414 (Akt3)
04660 T cell receptor signaling pathway
29414 (Akt3)
04662 B cell receptor signaling pathway
29414 (Akt3)
04664 Fc epsilon RI signaling pathway
29414 (Akt3)
04666 Fc gamma R-mediated phagocytosis
29414 (Akt3)
04062 Chemokine signaling pathway
29414 (Akt3)
09152 Endocrine system
04910 Insulin signaling pathway
29414 (Akt3)
04922 Glucagon signaling pathway
29414 (Akt3)
04923 Regulation of lipolysis in adipocytes
29414 (Akt3)
04920 Adipocytokine signaling pathway
29414 (Akt3)
04929 GnRH secretion
29414 (Akt3)
04915 Estrogen signaling pathway
29414 (Akt3)
04914 Progesterone-mediated oocyte maturation
29414 (Akt3)
04917 Prolactin signaling pathway
29414 (Akt3)
04926 Relaxin signaling pathway
29414 (Akt3)
04935 Growth hormone synthesis, secretion and action
29414 (Akt3)
04919 Thyroid hormone signaling pathway
29414 (Akt3)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
29414 (Akt3)
09154 Digestive system
04973 Carbohydrate digestion and absorption
29414 (Akt3)
09156 Nervous system
04725 Cholinergic synapse
29414 (Akt3)
04728 Dopaminergic synapse
29414 (Akt3)
04722 Neurotrophin signaling pathway
29414 (Akt3)
09158 Development and regeneration
04380 Osteoclast differentiation
29414 (Akt3)
09149 Aging
04211 Longevity regulating pathway
29414 (Akt3)
04213 Longevity regulating pathway - multiple species
29414 (Akt3)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
29414 (Akt3)
05205 Proteoglycans in cancer
29414 (Akt3)
05230 Central carbon metabolism in cancer
29414 (Akt3)
05231 Choline metabolism in cancer
29414 (Akt3)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
29414 (Akt3)
09162 Cancer: specific types
05210 Colorectal cancer
29414 (Akt3)
05212 Pancreatic cancer
29414 (Akt3)
05225 Hepatocellular carcinoma
29414 (Akt3)
05226 Gastric cancer
29414 (Akt3)
05214 Glioma
29414 (Akt3)
05221 Acute myeloid leukemia
29414 (Akt3)
05220 Chronic myeloid leukemia
29414 (Akt3)
05218 Melanoma
29414 (Akt3)
05211 Renal cell carcinoma
29414 (Akt3)
05215 Prostate cancer
29414 (Akt3)
05213 Endometrial cancer
29414 (Akt3)
05224 Breast cancer
29414 (Akt3)
05222 Small cell lung cancer
29414 (Akt3)
05223 Non-small cell lung cancer
29414 (Akt3)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
29414 (Akt3)
05170 Human immunodeficiency virus 1 infection
29414 (Akt3)
05161 Hepatitis B
29414 (Akt3)
05160 Hepatitis C
29414 (Akt3)
05164 Influenza A
29414 (Akt3)
05162 Measles
29414 (Akt3)
05168 Herpes simplex virus 1 infection
29414 (Akt3)
05163 Human cytomegalovirus infection
29414 (Akt3)
05167 Kaposi sarcoma-associated herpesvirus infection
29414 (Akt3)
05169 Epstein-Barr virus infection
29414 (Akt3)
05165 Human papillomavirus infection
29414 (Akt3)
09171 Infectious disease: bacterial
05132 Salmonella infection
29414 (Akt3)
05135 Yersinia infection
29414 (Akt3)
05152 Tuberculosis
29414 (Akt3)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
29414 (Akt3)
05142 Chagas disease
29414 (Akt3)
09164 Neurodegenerative disease
05010 Alzheimer disease
29414 (Akt3)
05017 Spinocerebellar ataxia
29414 (Akt3)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
29414 (Akt3)
05418 Fluid shear stress and atherosclerosis
29414 (Akt3)
05415 Diabetic cardiomyopathy
29414 (Akt3)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
29414 (Akt3)
04931 Insulin resistance
29414 (Akt3)
04933 AGE-RAGE signaling pathway in diabetic complications
29414 (Akt3)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
29414 (Akt3)
01524 Platinum drug resistance
29414 (Akt3)
01522 Endocrine resistance
29414 (Akt3)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rno01001
]
29414 (Akt3)
Enzymes [BR:
rno01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
29414 (Akt3)
Protein kinases [BR:
rno01001
]
Serine/threonine kinases: AGC group
AKT/PKB family
29414 (Akt3)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
PH
Kinase-like
Pkinase_C
ABC1
PH_11
Motif
Other DBs
NCBI-GeneID:
29414
NCBI-ProteinID:
NP_113763
RGD:
62390
Ensembl:
ENSRNOG00000021497
UniProt:
Q63484
LinkDB
All DBs
Position
13
AA seq
479 aa
AA seq
DB search
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDDDGMDCMDNERRPHFPQFSYSASGRE
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgagcgatgttaccatcgttaaagaaggctgggttcagaagaggggagaatatataaaa
aattggaggccaagatacttccttttgaagacagacggctcattcataggctataaagag
aaacctcaagatgtggacttaccttatcccctcaacaacttctcagtggcaaaatgtcaa
ttaatgaaaacagaacgaccaaagccaaatacatttattatcagatgtcttcagtggacc
actgttatagagagaacatttcatgtagatactccagaggaaagagaagaatggacagaa
gctatccaagctgtagccgatcgactgcagaggcaagaagaggagaggatgaattgtagt
ccaacgtcacagattgataatattggagaggaagagatggatgcatctacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactgctaggtaaaggcacttttggg
aaggttattttggttcgagagaaggcaagtggaaaatactacgctatgaagattctgaag
aaagaagtcattatcgcaaaggatgaagtggcacatactctgactgagagcagagttcta
aagaacaccagacatccatttctaacatccttgaaatattccttccagacaaaagaccgt
ttgtgttttgtgatggaatatgttaatgggggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgctttggac
tatctacattctggaaagattgtgtaccgagatctcaagttggagaatttgatgctagat
aaggatggccatataaaaattacggattttggactttgcaaagaagggatcacagatgca
gctaccatgaagacattctgtggtacaccagagtatctggcaccagaggtattagaagat
aatgactatggccgagctgtggactggtggggcctaggtgttgtcatgtatgaaatgatg
tgtgggaggttgcctttctacaaccaggatcatgagaaactctttgaactaatactcatg
gaagacatcaaattcccccgaacactctcttcagatgcaaagtcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggagggccagatgatgcaaaagagataatg
aggcacagtttcttttctggagtaaactggcaggacgtatatgacaaaaagcttgtacct
ccttttaagcctcaagtaacatctgagacagacaccagatatttcgatgaagaatttaca
gctcagactattacaataacaccacctgaaaagtatgacgacgacggcatggactgcatg
gataatgagcggcggccacacttccctcagttctcctactctgcaagcggacgggaataa
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integrated database retrieval system
