KEGG   Rattus norvegicus (rat): 24239
Entry
24239             CDS       T01003                                 

Gene name
Cacna1c
Definition
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
  KO
K04850  voltage-dependent calcium channel L type alpha-1C
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04260  Cardiac muscle contraction
rno04261  Adrenergic signaling in cardiomyocytes
rno04270  Vascular smooth muscle contraction
rno04713  Circadian entrainment
rno04720  Long-term potentiation
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04727  GABAergic synapse
rno04728  Dopaminergic synapse
rno04742  Taste transduction
rno04911  Insulin secretion
rno04912  GnRH signaling pathway
rno04921  Oxytocin signaling pathway
rno04924  Renin secretion
rno04925  Aldosterone synthesis and secretion
rno04927  Cortisol synthesis and secretion
rno04929  GnRH secretion
rno04930  Type II diabetes mellitus
rno04934  Cushing syndrome
rno04935  Growth hormone synthesis, secretion and action
rno05010  Alzheimer disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05031  Amphetamine addiction
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    24239 (Cacna1c)
   04020 Calcium signaling pathway
    24239 (Cacna1c)
   04024 cAMP signaling pathway
    24239 (Cacna1c)
   04022 cGMP-PKG signaling pathway
    24239 (Cacna1c)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    24239 (Cacna1c)
   04929 GnRH secretion
    24239 (Cacna1c)
   04912 GnRH signaling pathway
    24239 (Cacna1c)
   04921 Oxytocin signaling pathway
    24239 (Cacna1c)
   04935 Growth hormone synthesis, secretion and action
    24239 (Cacna1c)
   04924 Renin secretion
    24239 (Cacna1c)
   04925 Aldosterone synthesis and secretion
    24239 (Cacna1c)
   04927 Cortisol synthesis and secretion
    24239 (Cacna1c)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    24239 (Cacna1c)
   04261 Adrenergic signaling in cardiomyocytes
    24239 (Cacna1c)
   04270 Vascular smooth muscle contraction
    24239 (Cacna1c)
  09156 Nervous system
   04724 Glutamatergic synapse
    24239 (Cacna1c)
   04727 GABAergic synapse
    24239 (Cacna1c)
   04725 Cholinergic synapse
    24239 (Cacna1c)
   04728 Dopaminergic synapse
    24239 (Cacna1c)
   04726 Serotonergic synapse
    24239 (Cacna1c)
   04720 Long-term potentiation
    24239 (Cacna1c)
   04723 Retrograde endocannabinoid signaling
    24239 (Cacna1c)
  09157 Sensory system
   04742 Taste transduction
    24239 (Cacna1c)
  09159 Environmental adaptation
   04713 Circadian entrainment
    24239 (Cacna1c)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    24239 (Cacna1c)
   05020 Prion disease
    24239 (Cacna1c)
   05022 Pathways of neurodegeneration - multiple diseases
    24239 (Cacna1c)
  09165 Substance dependence
   05031 Amphetamine addiction
    24239 (Cacna1c)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    24239 (Cacna1c)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    24239 (Cacna1c)
   05414 Dilated cardiomyopathy
    24239 (Cacna1c)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    24239 (Cacna1c)
   04934 Cushing syndrome
    24239 (Cacna1c)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    24239 (Cacna1c)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   24239 (Cacna1c)
SSDB
Motif
Pfam: Ion_trans CAC1F_C GPHH Ca_chan_IQ PKD_channel Etmic-2 DUF4834
Other DBs
NCBI-GeneID: 24239
NCBI-ProteinID: NP_036649
RGD: 2245
Ensembl: ENSRNOG00000007090
UniProt: P22002 Q71QJ6 A0SLC4
LinkDB
Structure
PDB: 
1VYT

Position
4
AA seq 2170 aa
MIRAFAQPSTPPYQPLSSCLSEDTERKFKGKVVHEAQLNCFYISPGGSNYGSPRPAHANM
NANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTVSSTQRKRQQYGKPK
KQGGTTATRPPRALLCLTLKNPIRRACISIVEWKSFEIIILLTIFANCVALAIYIPFPED
DSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSA
ILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLH
IALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIIDVPAEEDPSPCALETGHGRQCQNGT
VCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLVI
FGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDPE
NEDEGMDEDKPRNMSMPTSETESVNTENVAGGDIEGENCGARLAHRISKSKFSRYWRRWN
RFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASEHYNQPHWLTEVQDTANKALLALFTAE
MLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETILVETKIMSPLGISVLRCVRLLRIFKI
TRYWNSLSNLVASLLNSVRSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFD
NFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSFPGMLVCIYFIILFICGNYILLNVFLA
IAVDNLADAESLTSAQKEEEEEKERKKLARTASPEKKQEVMEKPAVEESKEEKIELKSIT
ADGESPPTTKINMDDLQPSENEDKSPHSNPDTAGEEDEEEPEMPVGPRPRPLSELHLKEK
AVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTNLILFFILLSSISLAAEDPVQHTSFRN
HILFYFDIVFTTIFTIEIALKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSA
INVVKILRVLRVLRPLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQL
FKGKLYTCSDSSKQTEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFT
VSTFEGWPELLYRSIDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQ
EQGEQEYKNCELDKNQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLIL
LNTICLAMQHYGQSCLFKIAMNILNMLFTGLFTVEMILKLIAFKPKHYFCDAWNTFDALI
VVGSIVDIAITEVHPAEHTQCSPSMSAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLL
WTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLF
RCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINL
FVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGF
GKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIK
KIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKEQGLVGKPSQRNALS
LQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIFRRAGGLFGNHVSYY
QSDSRSNFPQTFATQRPLHINKTGNNQADTESPSHEKLVDSTFTPSSYSSTGSNANINNA
NNTALGRFPHPAGYSSTVSTVEGHGPPLSPAVRVQEAAWKLSSKRCHSRESQGATVSQDM
FPDETRSSVRLSEEVEYCSEPSLLSTDILSYQDDENRQLTCLEEDKREIQPSPKRSFLRS
ASLGRRASFHLECLKRQKDQGGDISQKTALPLHLVHHQALAVAGLSPLLQRSHSPSTFPR
PRPTPPVTPGSRGRPLQPIPTLRLEGAESSEKLNSSFPSIHCSSWSEETTACSGGSSMAR
RARPVSLTVPSQAGAPGRQFHGSASSLVEAVLISEGLGQFAQDPKFIEVTTQELADACDM
TIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQDRAVVPEDESCVYALGRGRSEEAL
PDSRSYVSNL
NT seq 6513 nt   +upstreamnt  +downstreamnt
atgattcgggccttcgctcagccatccacacccccataccagccgctctccagttgcctg
tctgaggacacagagaggaagttcaagggcaaggtggtacacgaagctcaactcaactgt
ttctacatttctcctggaggttccaactatgggagcccacgcccagctcatgccaacatg
aatgccaatgcagctgcaggacttgcccccgagcacatccctactccaggggcagcactg
tcctggcaggcagccatcgatgccgcccggcaggccaagttaatgggcagtgctggcaat
gcgaccatctctaccgtcagttccacacagcggaagcggcagcagtatgggaaacccaag
aagcaggggggcacaactgccacacggccgccccgggctctgctctgcctgactctgaag
aaccccatcaggagggcatgcatcagcattgttgaatggaaatcatttgaaataattatt
ttattgacgatttttgccaattgtgtggccttagcaatctatattccctttccggaagat
gactccaacgccaccaactccaacctggaacgggtggagtatctcttcctcatcattttt
accgtggaagcatttttaaaagtgattgcctacggactactcttccaccccaacgcttac
ctccgcaacggttggaatttactagattttataatcgtggttgtagggctttttagtgca
attttagaacaagcaaccaaagctgacggggccaacgctctgggagggaaaggagcggga
ttcgatgtgaaggcactgagagctttccgtgtgcttcgtcccctgcggctggtgtctgga
gtcccaagtctccaggtggtcctgaactccatcatcaaggccatggtgcccctgctgcac
attgccctcctcgtgctcttcgtcatcatcatctatgccattatcggcctggagctcttc
atggggaagatgcacaagacctgctacaaccaggagggcataatagatgttccagcggaa
gaggatccctccccttgtgctttggagacaggccatgggcgacagtgtcagaacgggacc
gtgtgcaagcccgggtgggatgggcccaagcacggcatcaccaacttcgacaacttcgcc
ttcgccatgctgacggtgttccagtgtatcaccatggagggctggacagacgtgctgtac
tggatgcaagacgctatgggctatgagttgccctgggtgtattttgtcagtctggtcatc
tttggatcctttttcgttctaaatctggttctcggtgttttgagcggagagttttccaaa
gagagggagaaagccaaagctcgaggagacttccagaagcttcgtgagaagcagcagcta
gaagaagatctcaaaggctacctggactggatcacccaggcggaagacatagaccctgag
aatgaggacgagggcatggatgaagacaaaccccgaaacatgagcatgcccacaagtgag
actgagtctgtcaacaccgaaaacgtggctggaggtgacatcgagggtgaaaactgtgga
gcccggcttgcccaccggatctccaaatccaagttcagccgctactggcgccggtggaat
agattctgcagaagaaagtgccgtgccgcagttaagtccaatgtcttctactggctggtg
atcttcctggtgttcctcaacaccctcaccattgcctccgaacactacaaccagcctcat
tggctcacagaagtgcaagacacggccaacaaggccctcctggcccttttcacggcagaa
atgctcctgaagatgtacagcctgggtctgcaggcctactttgtatccctcttcaaccgc
tttgactgtttcattgtgtgcgggggcatcctggagaccatcctggtggagacgaagatc
atgtcgcccctgggcatctctgtgctgagatgtgtgcggctgctcaggattttcaagatc
accaggtactggaactccctgagcaacctcgtggcgtccttgctgaactcagtgcgctcc
atcgcctccctgctgctactcctcttcctcttcatcatcatcttctccctcctggggatg
cagctgtttggtggaaagttcaactttgatgagatgcagacccgtaggagcacgtttgat
aacttcccacagtctctcctcactgtgtttcagatcctgaccggggaggactggaattcg
gtgatgtatgatgggatcatggcttatggcggcccctcttttccagggatgttagtctgt
atttacttcatcatcctcttcatctgtggaaattatatcctactgaatgtgttcttggcc
attgcggtggacaacctggctgatgcggagagcctgacctctgcccaaaaagaggaagaa
gaagagaaggagagaaagaagctggccaggactgccagcccagaaaagaaacaggaggtg
atggagaaaccagcagtagaggagagcaaagaggagaaaattgagctgaagtccattaca
gcagatggagaatccccacccactaccaagatcaacatggatgacctccagcccagtgaa
aatgaggacaagagtccccactccaacccagacactgcaggtgaagaggatgaggaggag
cccgagatgcctgtgggcccacgcccccggcccctgtctgagctgcaccttaaggaaaag
gcagtccccatgccggaagccagtgcatttttcatcttcagcccaaacaacaggttccgc
ctgcagtgccaccgcattgtcaatgacacgatcttcaccaacctcatcctcttcttcatt
ctgctcagtagcatctccctggcggctgaggaccccgtccagcacacctccttcaggaac
cacattctgttttattttgacattgtttttaccaccattttcaccattgaaattgctcta
aagatgactgcttacggggctttcctgcacaagggctctttctgccgaaattacttcaat
atcctggacctgctggtggttagcgtgtccctcatctcctttggcattcagtccagcgcg
atcaacgttgtgaagattttaagagtgcttcgtgtcctcaggcccctgagggccatcaac
agggccaaggggctaaagcacgtcgttcagtgtgtgtttgtggccatccggaccattgga
aacattgtaattgtcaccactctgctgcagttcatgttcgcctgcattggggtccagctc
ttcaagggaaagctctatacctgttcggatagttccaaacagacggaggcagaatgcaag
ggtaactatataacatacaaagacggagaagttgaccaccccattatccagcctcgaagt
tgggagaacagcaagttcgactttgacaatgttctggcagccatgatggccctctttacc
gtctccaccttcgaggggtggccagagctgctgtaccgctccattgactcccacacagaa
gacaagggtcccatctacaactatcgtgtggagatctccatcttcttcatcatctacatc
atcatcattgccttcttcatgatgaacatcttcgtgggtttcgtcattgtcaccttccag
gagcagggggaacaagaatacaagaactgtgagctggacaagaaccagagacaatgtgtg
gaatatgccctcaaggcccgacccttgcgaaggtacatccccaagaaccagcaccagtac
aaagtgtggtacgtggtcaactccacctacttcgagtatctgatgttcgtcctcatcctg
ctcaacaccatctgcctggccatgcagcactacggccagagctgcctcttcaaaatcgcc
atgaatatactcaacatgcttttcactggcctcttcacggtggagatgatcctgaagctc
attgccttcaaacccaagcactatttctgtgatgcatggaatacatttgacgccttgatt
gttgtgggtagcattgttgatatagcaatcaccgaggtacacccagctgaacatacccaa
tgctctccctctatgagtgcagaggagaactcccgcatctccatcaccttcttccgcctc
ttccgggtcatgcgcctggtgaagctgctgagccgaggggaaggcatccggaccctgctg
tggaccttcatcaagtccttccaggccctgccctatgtggcccttttgattgtgatgctg
ttctttatctatgcagtgattgggatgcaggtatttgggaagattgccctgaatgacacc
acagagatcaatcggaacaacaacttccagacgttccctcaggctgtgctactgctcttc
aggtgcgccactggggaggcctggcaggatatcatgctagcctgtatgccaggcaagaag
tgtgctccagagtctgagcccagcaacagcacggaaggggagacaccctgtggcagcagt
ttcgctgtcttctacttcatcagcttctacatgctctgtgccttcctgatcatcaacctc
tttgtagctgttatcatggacaactttgactacctgactagggattggtctatccttggt
ccccatcacctggatgaattcaagagaatctgggccgaatatgaccctgaagccaagggt
cggatcaaacacttggatgtggtgaccctcctccgtcgaattcagcccccactgggtttt
gggaagttgtgtcctcaccgtgtggcctgcaaacgcctggtgtccatgaacatgcctctg
aacagtgatgggacggtcatgttcaatgctacactgtttgcccttgtcaggacagccctg
aggatcaaaacagaagggaacctagagcaagccaatgaggagctgagagccatcatcaag
aaaatctggaagaggaccagcatgaagctgttggaccaggtggtgccccctgcaggtgat
gacgaggtcacagtgggcaagttctatgccaccttcctgatccaagagtacttcaggaaa
ttcaagaagcgaaaagagcaggggctggtcggcaagccctcgcagaggaatgcactgtct
ctgcaggctggcttacgcaccttgcatgacattgggcctgagatccggagagccatctct
ggggatctgacggctgaggaggagctggacaaggctatgaaggaggcagtgtctgctgcc
tccgaagacgacatcttcaggagggctggaggcctgtttggcaaccacgtcagctactac
cagagtgacagcaggagcaacttccctcagacgtttgccacccaacgcccactgcacatc
aacaagacagggaacaaccaagcggacaccgaatcaccgtcccatgagaagctggtggac
tccactttcacccccagcagctactcatccacgggctccaatgccaacatcaacaatgcc
aacaacactgccctgggccgcttcccccaccctgctggctactccagcacggtcagcact
gtggagggccatgggcctcccttgtcccctgctgtccgggtacaggaggcagcatggaaa
ctcagctctaagaggtgccactcccgagagagccagggggccacggtgagtcaggatatg
tttccagatgagacccgcagcagcgtgaggctgagcgaagaagttgagtactgcagtgag
cccagcctgctctccacagatatactctcctaccaggacgatgaaaaccgacaactgacc
tgtctagaggaggacaagagggagatccagccatctccgaagaggagtttccttcgctct
gcctctctaggtcgaagggcctccttccatctggaatgtctaaagcgacaaaaggatcaa
gggggagacatctctcagaagacagccttgcccttgcatctggttcatcaccaggcattg
gcagtggcaggcttgagccccctcctgcagagaagccattctccttccacgttccccagg
ccacgccccacgccccctgtcactccaggcagccggggcaggcccctacagcccatccct
accctgcggctggagggggcggagtccagtgagaaactcaacagcagcttcccgtccatc
cactgcagctcctggtcagaggagaccacagcctgtagtgggggcagcagcatggcccgg
agagcccggcccgtctccctcaccgtgcccagccaggctggagctccaggcagacagttc
cacggcagcgccagcagcctggtggaagcggtcttgatttcagaaggactgggacagttt
gctcaagatcccaagttcatcgaggtcaccacacaggagctggctgacgcctgcgatatg
acaatagaggagatggagaacgccgcagacaacatcctcagcgggggcgcccagcagagc
cccaacggcaccctcttaccttttgtgaactgcagggacccagggcaggacagggctgtg
gtcccagaggacgagagctgtgtatatgccctggggcgaggccggagcgaggaagcgctc
ccggacagcaggtcctatgtcagcaacctgtag

KEGG   Rattus norvegicus (rat): 25398
Entry
25398             CDS       T01003                                 

Gene name
Cacna1a
Definition
(RefSeq) voltage-dependent P/Q-type calcium channel subunit alpha-1A
  KO
K04344  voltage-dependent calcium channel P/Q type alpha-1A
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04721  Synaptic vesicle cycle
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04727  GABAergic synapse
rno04728  Dopaminergic synapse
rno04730  Long-term depression
rno04742  Taste transduction
rno04930  Type II diabetes mellitus
rno05017  Spinocerebellar ataxia
rno05032  Morphine addiction
rno05033  Nicotine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    25398 (Cacna1a)
   04020 Calcium signaling pathway
    25398 (Cacna1a)
 09150 Organismal Systems
  09156 Nervous system
   04724 Glutamatergic synapse
    25398 (Cacna1a)
   04727 GABAergic synapse
    25398 (Cacna1a)
   04725 Cholinergic synapse
    25398 (Cacna1a)
   04728 Dopaminergic synapse
    25398 (Cacna1a)
   04726 Serotonergic synapse
    25398 (Cacna1a)
   04730 Long-term depression
    25398 (Cacna1a)
   04723 Retrograde endocannabinoid signaling
    25398 (Cacna1a)
   04721 Synaptic vesicle cycle
    25398 (Cacna1a)
  09157 Sensory system
   04742 Taste transduction
    25398 (Cacna1a)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05017 Spinocerebellar ataxia
    25398 (Cacna1a)
  09165 Substance dependence
   05032 Morphine addiction
    25398 (Cacna1a)
   05033 Nicotine addiction
    25398 (Cacna1a)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    25398 (Cacna1a)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    25398 (Cacna1a)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   25398 (Cacna1a)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 25398
NCBI-ProteinID: NP_037050
RGD: 2244
Ensembl: ENSRNOG00000052707
UniProt: P54282 O70368
LinkDB
Position
19
AA seq 2368 aa
MARFGDEMPGRYGAGGGGSGPAAGVVVGAAGGRGAGGSRQGGQPGAQRMYKQSMAQRART
MALYNPIPVRQNCLTVNRSLFLFSEDNVVRKYAKKITEWPPFEYMILATIIANCIVLALE
QHLPDDDKTPMSERLDDTEPYFIGIFCFEAGIKIVALGFAFHKGSYLRNGWNVMDFVVVL
TGILATVGTEFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMIPLLQIGLLLFFAIL
IFAIIGLEFYMGKFHTTCFEEGTDDIQGESPAPCGTEEPARTCPNGTKCQPYWEGPNNGI
TQFDNILFAVLTVFQCITMEGWTDLLYNSNDASGNTWNWLYFIPLIIIGSFFMLNLVLGV
LSGEFAKERERVENRRAFLKLRRQQQIERELNGYMEWISKAEEVILAEDETDVEQRHPFD
GALRRATLKKSKTDLLNPEEAEDQLADIASVGSPFARASIKSAKLENSTFFHKKERRMRF
YIRRMVKTQAFYWTVLSLVALNTLCVAIVHYNQPEWLSDFLYYAEFIFLGLFMSEMFIKM
YGLGTRPYFHSSFNCFDCGVIIGSIFEVIWAVIKPGTSFGISVLRALRLLRIFKVTKYWA
SLRNLVVSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFDEGTPPTNFDTFPAAI
MTVFQILTGEDWNEVMYDGIKSQGGVQGGMVFSIYFIVLTLFGNYTLLNVFLAIAVDNLA
NAQELTKDEQEEEEAANQKLALQKAKEVAEVSPLSAANMSIAVKEQQKNQKPAKSVWEQR
TSEMRKQNLLASREALYGDAAERWPTTYARPLRPDVKTHLDRPLVVDPQENRNNNTNKSR
APEALRQTARPRESARDPDARRAWPSSPERAPGREGPYGRESEPQQREHAPPREHVPWDA
DPERAKAGDAPRRHTHRPVAEGEPRRHRARRRPGDEPDDRPERRPRPRDATRPARAADGE
GDDGERKRRHRHGPPAHDDRERRHRRRKESQGSGVPMSGPNLSTTRPIQQDLGRQDLPLA
EDLDNMKNNKLATGEPASPHDSLGHSGLPPSPAKIGNSTNPGPALATNPQNAASRRTPNN
PGNPSNPGPPKTPENSLIVTNPSSTQPNSAKTARKPEHMAVEIPPACPPLNHTVVQVNKN
ANPDPLPKKEEEKKEEEEADPGEDGPKPMPPYSSMFILSTTNPLRRLCHYILNLRYFEMC
ILMVIAMSSIALAAEDPVQPNAPRNNVLRYFDYVFTGVFTFEMVIKMIDLGLVLHQGAYF
RDLWNILDFIVVSGALVAFAFTGNSKGKDINTIKSLRVLRVLRPLKTIKRLPKLKAVFDC
VVNSLKNVFNILIVYMLFMFIFAVVAVQLFKGKFFHCTDESKEFERDCRGKYLLYEKNEV
KARDREWKKYDFHYDNVLWALLTLFTVSTGEGWPQVLKHSVDATFENQGPSPGYRMEMSI
FYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEEYSLEKNERACIDFAISAKPLTRHMP
QNKQSFQYRMWQFVVSPPFEYTIMAMIALNTIVLMMKFYGASVAYENALRVFNIVFTSLF
SLECVLKVMAFGILNYFRDAWNIFDFVTVLGSITDILVTEFGNNFINLSFLRLFRAARLI
KLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIGIDGEDEDSDED
EFQITEHNNFRTFFQALMLLFRSATGEAWHNIMLSCLSGKPCDKNSGIQKPECGNEFAYF
YFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEYVRVWAEYDPAACGRIHY
KDMYSLLRVISPPLGLGKKCPHRVACKRLLRMDLPVADDNTVHFNSTLMALIRTALDIKI
AKGGADKQQMDAELRKEMMAIWPNLSQKTLDLLVTPHKSTDLTVGKIYAAMMIMEYYRQS
KAKKLQAMREEQNRTPLMFQRMEPPSPTQEGGPSQNALPSTQLDPGGGLMAQESSMKESP
SWVTQRAQEMFQKTGTWSPERGPPIDMPNSQPNSQSVEMREMGTDGYSDSEHYLPMEGQT
RAASMPRLPAENQRRRGRPRGNNLSTISDTSPMKRSASVLGPKARRLDDYSLERVPPEEN
QRYHQRRRDRGHRTSERSLGRYTDVDTGLGTDLSMTTQSGDLPSKDRDQDRGRPKDRKHR
PHHHHHHHHHHPPAPDRERYAQERPDTGRARAREQRWSRSPSEGREHATHRQGSSSVSGS
PAPSTSGTSTPRRGRRQLPQTPCTPRPLVSYSPAPRRPAARRMAGPPAPPGGSPRGCRRA
PRWPAHAPEGPRPRGADYTEPDSPREPPGGAHEPAPRSPRTPRAAGCASPRHGRRLPNGY
YAGHGAPRPRTARRGAHDAYSESEDDWC
NT seq 7107 nt   +upstreamnt  +downstreamnt
atggcccgctttggagacgagatgccgggccgctacggcgcaggcggaggaggctcaggg
ccggccgccggggtggtcgtgggcgccgcgggcggccgaggagccgggggcagccggcag
ggcgggcagcccggagcgcagaggatgtacaagcagtcgatggcgcagagagcgcggacc
atggccctctacaaccccatccctgtccgccagaactgcctcacggtcaaccgctccctg
ttcctcttcagtgaagacaacgtggtgagaaaatacgccaaaaagatcacggaatggcct
cccttcgagtacatgatcctggccaccatcattgctaactgcatcgtcctggccctggag
cagcacctccctgatgatgacaagacacccatgtccgagcggctggatgacacagaaccc
tatttcattggcatcttctgttttgaggctggaattaagatcgtggctcttggctttgcc
ttccacaaaggctcctacctgaggaatggctggaacgtcatggactttgtcgtggtgcta
acaggcatcttggccactgtcgggacggagtttgatctacggacactgagggcggttcgt
gtgctgcggccactcaagctggtgtctggaatcccaagtttacaagtcgtcctgaagtca
atcatgaaggcgatgatccctctgctgcagatcggcctcctcctgttttttgcaatcctt
atttttgcaatcatagggttagaattttatatgggaaaatttcataccacctgctttgaa
gaggggacagacgacatccagggtgagtcgccagctccgtgtgggacagaggagcctgcc
cgcacctgccccaacgggaccaaatgtcagccgtactgggaagggcccaacaacggcatc
actcagttcgacaacatcctgtttgctgtgctcactgttttccagtgcatcaccatggaa
ggctggactgatctcctctacaatagcaacgatgcctcagggaacacttggaactggttg
tacttcatccccctcatcatcatcggctccttttttatgctgaaccttgtgctgggtgtg
ctgtctggggagtttgccaaagaaagggaacgtgtagagaaccgaagggcttttctgaag
ctcagaagacaacagcagattgaacgtgagctcaatggatacatggagtggatctcgaaa
gcagaagaggtgatcctcgcggaggacgagacagacgtggagcagaggcacccttttgat
ggagctcttcggagagctactctgaagaaaagcaagacggacctgctcaaccctgaggag
gcggaggaccagcttgctgacatcgcgtctgtggggtctcccttcgccagagccagcatc
aaaagtgccaagctggagaattcgacttttttccacaaaaaggagagaagaatgcgtttc
tacatccgccgcatggtcaaaactcaggccttctactggaccgtgctcagtctggtagcc
ctcaacacgctgtgcgtcgccattgtccactacaaccagcccgagtggctctccgacttc
ctctactatgcagaattcattttcttaggactctttatgtccgaaatgtttataaaaatg
tatgggctcgggacacggccttacttccactcttccttcaactgctttgactgtggggtc
atcatcgggagcatctttgaagtcatctgggccgtcatcaaaccgggtacatcctttgga
atcagcgtgttacgagctctcaggttactgcgtattttcaaagtcacaaagtactgggca
tctctcagaaacctggttgtctccctcctcaactccatgaaatccatcataagtctgctg
ttcctcctcttcctcttcattgtcgtctttgccctcttggggatgcagctgtttggtggc
cagtttaattttgacgaggggactcctcccaccaacttcgacacttttccagcagcaata
atgactgtgtttcagatcctgactggcgaggattggaatgaggtcatgtatgatgggatc
aagtctcaggggggcgtgcagggcggcatggtgttctccatctacttcatcgtcctcacc
ctcttcgggaactacaccctgctgaacgtgttcttggctatcgcggtggacaacctggcc
aacgcccaggaactcaccaaggatgaacaagaagaggaagaggcagccaatcagaaactg
gctctacagaaagccaaggaggtggcagaagtgagtcccctgtctgcagccaacatgtcc
atagctgtgaaggaacagcagaagaaccagaagcctgccaagtcggtgtgggagcagcgc
accagcgagatgcgcaagcagaacctgctggctagccgcgaggcgctgtacggggacgcg
gctgagcgctggcccaccacttacgcgcgcccgctgcggccggacgtgaagacgcacttg
gaccggccgctcgtggtggacccgcaggagaaccgtaacaacaacaccaacaagagccgt
gcgccagaagcgctgcgccaaaccgcgcggccccgcgagagcgcgcgcgaccccgacgcg
cggcgcgcctggcccagcagccctgagcgcgcccctggacgagagggcccgtatggccgc
gagagcgagccgcaacagcgcgagcacgcgccaccccgcgagcacgtaccctgggacgcg
gatcctgagcgcgccaaggccggggacgcgccccgccgccacacgcaccggcctgtggcc
gagggcgagcctcgtcgccaccgcgcgcgccgccggcccggggacgaaccggacgacaga
ccggagcgcaggccgcgtccccgcgacgccactaggccggcccgcgctgcagacggcgaa
ggcgatgatggggagcgcaagcggcgacaccgacacgggccgccggcccacgatgacagg
gagcgcagacaccggcgcagaaaagagagccagggctctggggtccccatgtctggtccc
aacctgtccaccaccaggccaatccagcaggatctgggccgccaggacctgccactggct
gaggacctggacaacatgaagaacaacaagttggccaccggggagcctgccagtccccac
gacagcctgggccacagtggccttccccctagccctgccaagatcgggaacagcaccaac
cctggtcccgccttggccaccaatccccagaatgctgccagccgcaggacgcccaacaac
ccgggcaacccgtccaaccccggcccccccaagactcccgagaacagccttatcgtcacc
aaccccagcagcacccagcccaactcagcaaagactgccaggaaacccgagcacatggcg
gtggagatccccccggcctgcccgcccctcaaccacactgtggtccaagtaaacaaaaac
gccaacccagacccactgccaaagaaagaggaagagaagaaggaggaagaggaggcagac
cccggggaggatggcccaaagcccatgccgccctacagctccatgttcatcctctccacc
accaacccccttcgccggctgtgccattacatcctgaacctgcgctacttcgagatgtgc
atcctcatggtcattgccatgagtagcatcgcgctggccgccgaggacccggtgcagccc
aacgcaccccgcaacaacgtgctgcgatattttgactatgttttcacaggagtgtttacc
tttgagatggtgatcaagatgatcgacctgggcctcgtcctgcatcagggggcctatttc
cgtgacctgtggaacattctggacttcatagtggtcagtggggccctggtggcctttgcc
ttcactggcaatagcaaaggaaaggacatcaacaccatcaagtccctccgagtcctccgg
gtgctacgacctctaaagaccatcaagcggctgcctaagttgaaggccgtatttgactgc
gtggtgaactcgctcaagaacgtcttcaacatcctcattgtctacatgctcttcatgttc
atcttcgccgtggtggccgtgcagctcttcaagggcaaattcttccactgcacggacgag
tccaaggagtttgagagagactgtcgaggcaaatacctcctttacgagaagaacgaggta
aaggcgcgggaccgcgagtggaagaaatacgacttccactacgacaacgtgctctgggcc
ctgctcacgctctttacggtgtccacgggagagggctggccacaggtcctcaagcactca
gtggatgccacttttgagaaccagggccccagccccgggtaccgcatggaaatgtccatc
ttctacgtggtctactttgtggtgtttcccttcttctttgtcaatatctttgtggccttg
atcatcatcaccttccaggagcagggagacaagatgatggaagaatacagcctagagaaa
aatgagagggcctgcatcgactttgccatcagtgccaagccgctgaccaggcacatgccc
cagaacaagcagagcttccagtatcgaatgtggcagttcgtggtgtccccaccctttgag
tacaccatcatggccatgatcgctctcaacaccatcgtgctaatgatgaagttctatgga
gcctctgtggcctatgaaaacgcccttcgagtgttcaacattgtcttcacctccctcttc
tctctcgaatgtgtgctcaaagtcatggcttttgggattctgaattatttccgcgatgcc
tggaacatcttcgactttgtgactgttctgggcagcatcacagacatcctcgtcaccgag
tttgggaataacttcatcaacctgagctttctccgcctcttccgtgctgcccgactcatc
aaactcctccgccagggttacaccatccgcattctcctctggactttcgtgcagtctttc
aaggccctaccttatgtctgtctgctgatcgccatgctcttcttcatctatgccatcatc
gggatgcaggtgtttggcaacatcggcattgatggggaagatgaggacagcgatgaggat
gagttccaaatcacggagcacaataacttccggaccttcttccaagctctcatgcttctc
ttccggagcgccacaggggaagcgtggcacaacatcatgctgtcctgcctcagcgggaag
ccatgcgacaagaactccgggatccaaaaaccagagtgtggcaacgagttcgcctatttt
tactttgtctcgttcatcttcctttgctcatttctgatgctgaatctctttgttgctgtc
atcatggacaacttcgagtacctcacccgagattcctccatcctgggcccccaccacctg
gatgagtacgtgcgtgtctgggcagagtatgaccctgctgcctgcggccgcattcactat
aaggacatgtacagtttattgcgagtaatatcgccccctctcggcttaggcaagaaatgt
cctcatagggttgcttgcaagaggctcttgcggatggacctacccgtagcggatgacaac
accgttcacttcaactccaccttgatggctctgatccgaaccgccctggatatcaaaatc
gcaaagggtggagctgacaagcagcaaatggacgcagagctccgcaaggaaatgatggcc
atttggcccaacctgtctcagaagaccttggatctgctggtcacacctcacaagtccacg
gacctgacagtgggtaagatctacgcagccatgatgatcatggagtactaccggcagagc
aaggccaagaagctgcaggccatgcgagaggagcagaaccggacaccactcatgttccag
cgcatggagcctccatcgccaacacaggagggaggacccagccaaaacgcccttccctcc
actcagctggaccccggaggaggcctgatggctcaagaaagcagcatgaaggagagcccg
tcctgggtgacccagcgggcacaggagatgttccagaagactggtacctggagcccagag
cgagggccacccatcgacatgcctaacagccagcccaactcccagtctgtggagatgaga
gaaatgggaactgatggctactcagacagcgaacactacctccccatggaaggacagacc
agggccgcctccatgccccgcctcccagcagagaaccagaggagaaggggccggccacgt
ggaaataacctcagtaccatctctgataccagccccatgaagcgctcagcctccgtgctg
ggacccaaagcccggcgactggatgactactcactagagcgggtaccacctgaggagaac
caaaggtaccaccaacgccgccgggaccgtggccaccgcacctctgagcgctctctgggc
cgatacactgatgtggacacaggcctggggacagatctgagcatgaccacccaatcgggt
gacctgccctccaaagatcgggaccaggaccggggccggcccaaggaccggaagcatcgg
ccacaccaccaccaccaccatcatcaccatcatcccccggccccggaccgggagcgctac
gcacaggagcggccggacaccggccgggcgcgggcccgggagcagcgctggtcccgctcg
cccagcgagggtcgggagcacgcgacacacagacagggcagtagttccgtcagtggaagc
ccagccccctctacgtccggcaccagcacgccgcggcgcggccgccgccagctcccccag
accccctgcaccccgcggccgcttgtgtcctactcgcccgctccgcgcaggcctgcggcg
cgcaggatggcgggtcccccagcgccccctggcggctcgccgcggggttgccgccgtgcg
ccgcgctggcctgcgcatgcgcctgagggcccgcggccgcgcggtgccgactacaccgag
cccgacagcccgcgcgagccgccagggggcgcgcatgagcccgcgccgcggtcgcccagg
actccgcgcgccgcgggctgcgcgtcaccgcgccacggccgcaggctgcccaatggttac
tacgcggggcacggcgcgccacggccgcgcacagcccgcaggggcgcgcacgacgcgtac
agcgagagcgaggacgactggtgctaa

KEGG   Rattus norvegicus (rat): 257648
Entry
257648            CDS       T01003                                 

Gene name
Cacna1b
Definition
(RefSeq) voltage-dependent N-type calcium channel subunit alpha-1B isoform 1
  KO
K04849  voltage-dependent calcium channel N type alpha-1B
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04721  Synaptic vesicle cycle
rno04723  Retrograde endocannabinoid signaling
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04727  GABAergic synapse
rno04728  Dopaminergic synapse
rno04930  Type II diabetes mellitus
rno05016  Huntington disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05032  Morphine addiction
rno05033  Nicotine addiction
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    257648 (Cacna1b)
   04020 Calcium signaling pathway
    257648 (Cacna1b)
 09150 Organismal Systems
  09156 Nervous system
   04727 GABAergic synapse
    257648 (Cacna1b)
   04725 Cholinergic synapse
    257648 (Cacna1b)
   04728 Dopaminergic synapse
    257648 (Cacna1b)
   04726 Serotonergic synapse
    257648 (Cacna1b)
   04723 Retrograde endocannabinoid signaling
    257648 (Cacna1b)
   04721 Synaptic vesicle cycle
    257648 (Cacna1b)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05016 Huntington disease
    257648 (Cacna1b)
   05020 Prion disease
    257648 (Cacna1b)
   05022 Pathways of neurodegeneration - multiple diseases
    257648 (Cacna1b)
  09165 Substance dependence
   05032 Morphine addiction
    257648 (Cacna1b)
   05033 Nicotine addiction
    257648 (Cacna1b)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    257648 (Cacna1b)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    257648 (Cacna1b)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   257648 (Cacna1b)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 257648
NCBI-ProteinID: NP_001182128
RGD: 628852
Ensembl: ENSRNOG00000004560
UniProt: E1AW38
LinkDB
Structure
PDB: 
4DEX

Position
3
AA seq 2354 aa
MVRFGDELGGRYGGTGGGERARGGGAGGAGGPGQGGLPPGQRVLYKQSIAQRARTMALYN
PIPVKQNCFTVNRSLFVFSEDNVVRKYAKRITEWPPFEYMILATIIANCIVLALEQHLPD
GDKTPMSERLDDTEPYFIGIFCFEAGIKIIALGFVFHKGSYLRNGWNVMDFVVVLTGILA
TAGTDFDLRTLRAVRVLRPLKLVSGIPSLQVVLKSIMKAMVPLLQIGLLLFFAILMFAII
GLEFYMGKFHKACFPNSTDAEPVGDFPCGKEAPARLCDSDTECREYWPGPNFGITNFDNI
LFAILTVFQCITMEGWTDILYNTNDAAGNTWNWLYFIPLIIIGSFFMLNLVLGVLSGEFA
KERERVENRRAFLKLRRQQQIERELNGYLEWIFKAEEVMLAEEDKNAEEKSPLDAVLKRA
ATKKSRNDLIHAEEGEDRFVDLCAAGSPFARASLKSGKTESSSYFRRKEKMFRFLIRRMV
KAQSFYWVVLCVVALNTLCVAMVHYNQPQRLTTALYFAEFVFLGLFLTEMSLKMYGLGPR
SYFRSSFNCFDFGVIVGSIFEVVWAAIKPGTSFGISVLRALRLLRIFKVTKYWNSLRNLV
VSLLNSMKSIISLLFLLFLFIVVFALLGMQLFGGQFNFQDETPTTNFDTFPAAILTVFQI
LTGEDWNAVMYHGIESQGGVSKGMFSSFYFIVLTLFGNYTLLNVFLAIAVDNLANAQELT
KDEEEMEEAANQKLALQKAKEVAEVSPMSAANISIAAFVKQTRGTVSRSSSVSSVNSPQQ
NSAKARSVWEQRASQLRLQNLRASCEALYSEMDPEERLRYASTRHVRPDMKTHMDRPLVV
EPGRDGLRGPAGNKSKPEGTEATEGADPPRRHHRHRDRDKTSASTPAGGEQDRTDCPKAE
STETGAREERARPRRSHSKEAPGADTQVRCERSRRHHRRGSPEEATEREPRRHRAHRHAQ
DSSKEGKEGTAPVLVPKGERRARHRGPRTGPRETENSEEPTRRHRAKHKVPPTLEPPERE
VAEKESNVVEGDKETRNHQPKEPRCDLEAIAVTGVGSLHMLPSTCLQKVDEQPEDADNQR
NVTRMGSQPSDPSTTVHVPVTLTGPPGEATVVPSANTDLEGQAEGKKEAEADDVLRRGPR
PIVPYSSMFCLSPTNLLRRFCHYIVTMRYFEMVILVVIALSSIALAAEDPVRTDSFRNNA
LKYMDYIFTGVFTFEMVIKMIDLGLLLHPGAYFRDLWNILDFIVVSGALVAFAFSGSKGK
DINTIKSLRVLRVLRPLKTIKRLPKLKAVFDCVVNSLKNVLNILIVYMLFMFIFAVIAVQ
LFKGKFFYCTDESKELERDCRGQYLDYEKEEVEAQPRQWKKYDFHYDNVLWALLTLFTVS
TGEGWPMVLKHSVDATYEEQGPSPGFRMELSIFYVVYFVVFPFFFVNIFVALIIITFQEQ
GDKVMSECSLEKNERACIDFAISAKPLTRYMPQNKQSFQYKTWTFVVSPPFEYFIMAMIA
LNTVVLMMKFYDAPYEYELMLKCLNIVFTSMFSLECILKIIAFGVLNYFRDAWNVFDFVT
VLGSITDILVTEIAETNNFINLSFLRLFRAARLIKLLRQGYTIRILLWTFVQSFKALPYV
CLLIAMLFFIYAIIGMQVFGNIALDDGTSINRHNNFRTFLQALMLLFRSATGEAWHEIML
SCLGNRACDPHANASECGSDFAYFYFVSFIFLCSFLMLNLFVAVIMDNFEYLTRDSSILG
PHHLDEFIRVWAEYDPAACGRISYNDMFEMLKHMSPPLGLGKKCPARVAYKRLVRMNMPI
SNEDMTVHFTSTLMALIRTALEIKLAPAGTKQHQCDAELRKEISSVWANLPQKTLDLLVP
PHKPDEMTVGKVYAALMIFDFYKQNKTTRDQTHQAPGGLSQMGPVSLFHPLKATLEQTQP
AVLRGARVFLRQKSATSLSNGGAIQTQESGIKESLSWGTQRTQDVLYEARAPLERGHSAE
IPVGQPGALAVDVQMQNMTLRGPDGEPQPGLESQGRAASMPRLAAETQPAPNASPMKRSI
STLAPRPHGTQLCNTVLDRPPPSQVSHHHHHRCHRRRDKKQRSLEKGPSLSVDTEGAPST
AAGSGLPHGEGSTGCRRERKQERGRSQERRQPSSSSSEKQRFYSCDRFGSREPPQPKPSL
SSHPISPTAALEPGPHPQGSGSVNGSPLMSTSGASTPGRGGRRQLPQTPLTPRPSITYKT
ANSSPVHFAEGQSGLPAFSPGRLSRGLSEHNALLQKEPLSQPLASGSRIGSDPYLGQRLD
SEASAHNLPEDTLTFEEAVATNSGRSSRTSYVSSLTSQSHPLRRVPNGYHCTLGLSTGVR
ARHSYHHPDQDHWC
NT seq 7065 nt   +upstreamnt  +downstreamnt
atggtccgcttcggggacgagctaggcggccgctatgggggcaccggcggcggggagcgg
gctcggggcggcggggccggcggggccggtggcccgggccaggggggtctgccgccgggc
cagcgggtcctgtacaagcagtccattgcgcaacgcgcacggaccatggccctgtacaac
cccatcccagtcaagcagaactgcttcaccgtcaaccgctcgctcttcgtcttcagcgag
gacaacgtcgtccgcaaatatgctaagcgcatcaccgaatggccgcccttcgaatatatg
atcctggccaccatcatcgccaactgtattgtcctggccctggagcagcacctccctgat
ggggacaagactcccatgtctgaacgactggatgacacggaaccttacttcatcggcatc
ttttgcttcgaggcgggcatcaagatcatagctctgggcttcgtgttccacaaaggctcc
tacctccggaatggctggaacgtcatggacttcgtggtggtcctcacagggattcttgcc
acagctggaactgactttgatctgcgcaccctgagggctgtgcgtgtgcttaggcccctg
aagttggtgtctggaattccaagcttgcaggtggtgctcaagtccatcatgaaggccatg
gtcccgctgctgcagatcgggctgctgctcttcttcgccatcctcatgttcgctatcatc
ggcctcgagttctatatgggcaaattccataaggcctgcttccccaacagcacagatgca
gagcctgtgggtgactttccttgtggcaaggaggcccctgctcgtctgtgtgacagtgac
accgaatgccgggagtactggccaggacccaactttggcatcaccaattttgacaacatc
ctgtttgccatcttgaccgtgttccagtgtatcaccatggagggctggactgacatcctc
tacaatacaaatgatgcggccggcaacacgtggaactggttgtacttcatccccctcatc
atcattggctccttcttcatgctcaacctggtgctcggtgtgctttcaggagagtttgcc
aaagagcgggagcgagtcgagaaccgccgtgccttcctgaagctccgcaggcagcagcag
attgagcgagaactgaatgggtacttggagtggatcttcaaggcggaggaagtcatgttg
gcagaggaggacaagaacgcagaagagaagtcccctttggatgcagtgttgaagagagct
gctaccaagaagagccgaaatgacctcatccatgcagaagagggggaggaccggtttgta
gacctctgtgctgctgggtctccctttgctcgtgccagcctcaagagtgggaagacagag
agctcatcgtacttccggaggaaggagaagatgttccggttccttatccgtcgtatggtg
aaagcacagagcttctactgggtggtactgtgcgtggtggccctgaacacgttgtgtgtg
gccatggtacactataatcagcctcagcggcttaccactgcactgtactttgcagagttt
gttttcctgggtctcttcctcacagagatgtccctgaagatgtacggtctagggcccaga
agctacttccggtcttccttcaactgctttgactttggggtgattgtggggagtatcttt
gaagtagtctgggctgccatcaagccaggaacctccttcggaatcagtgtgctgcgggct
ctccgactgctgaggattttcaaagtcaccaagtattggaactccctgaggaacctggtt
gtttccctcctcaactccatgaagtccatcatcagccttctcttcctgcttttccttttc
attgtggtcttcgctctgttggggatgcagctgtttgggggacagttcaactttcaagat
gagactccaaccaccaattttgataccttcccagctgccatcctcactgtgtttcagatt
ctgacaggagaggactggaatgcagtcatgtatcatgggattgagtcacaaggaggagtc
agcaaaggcatgttttcatccttttacttcatcgtcctgacactgtttggaaactacacc
ctgttgaacgttttcttggccattgctgtggacaaccttgccaatgcccaggagttgacc
aaggatgaagaggagatggaagaggcagccaatcagaagcttgctcttcagaaggccaaa
gaagtagctgaagtcagccccatgtctgctgccaacatctccattgctgcttttgtaaag
caaactcgaggtactgtatctcgcagctcatctgtctccagcgtaaactcaccgcagcag
aactcggccaaggcgcgctcagtatgggagcagcgggccagtcagctaaggctccagaac
ctgcgtgccagctgtgaggcactgtacagtgagatggacccggaggagcgcctgcgttat
gccagcacgcgccacgtgaggccagacatgaagacacacatggaccgacccctagtggtg
gaacctggtcgggatggcctgcggggacccgccgggaacaagtcaaagcctgagggcacg
gaggccaccgaaggtgcggatccaccacgccgacaccaccggcatcgtgatagggacaag
acctcagcctcaacccctgctggaggcgaacaggacaggacagactgcccaaaggccgaa
agcaccgagaccggggcccgggaggaacgtgcgcgccctcgtcgaagtcacagcaaggag
gctccaggggctgacacacaagtgcgttgtgagcgcagtagacgtcaccaccggcgcgga
tccccggaggaggccactgaacgggaacctcggcgccaccgtgcccaccggcacgcacag
gactcaagcaaggaaggcaaggagggcactgcaccggtgcttgtacccaagggcgagcgt
cgcgcaagacatcgaggcccgcgtacgggcccccgtgagacagagaacagtgaggagccc
acacgcaggcaccgtgcaaagcataaggtgccaccaacacttgagcccccagagagggag
gttgcagagaaggagagcaacgtggtggaaggggataaggaaactcgaaatcaccagccc
aaggaacctcgctgtgacctggaggccattgcggttacaggcgtgggctctctgcacatg
ctgcccagcacctgtctccagaaagtggacgaacagccagaggatgcagacaaccagcgt
aatgtcacccggatgggcagtcagccctcagaccccagcaccactgtgcatgtcccagtg
acactgacaggccctcccggggaggccactgtagttcccagtgctaacacggacctggaa
ggccaagcggagggcaagaaggaggcagaggctgacgatgtgctgagaagaggccccagg
cccatcgttccctacagttccatgttctgcctcagccccaccaacctactccgtcgcttc
tgccattacattgtgaccatgcggtactttgagatggtgattcttgtggtcatcgccttg
agcagcattgccctggctgctgaggatcccgtgcggaccgactcattccggaacaatgct
ctgaagtacatggactacatctttacaggagtcttcacctttgagatggtcataaagatg
atagacttgggcctgctgctgcaccctggggcctacttccgggacctgtggaacattctg
gacttcattgttgtcagtggagccctggtggcatttgcattctcaggatccaaagggaaa
gacatcaataccatcaagtctctgagagtcctgcgagtcctgcggcccctcaagaccatc
aagcggctgcctaaactcaaggctgtgtttgactgtgtggtgaactctctgaagaatgtc
ttgaacatcctgatcgtctacatgctcttcatgtttatatttgccgtcatcgccgtccaa
ctcttcaaagggaagttcttttactgcactgatgagtccaaggagctggagcgggactgc
aggggtcagtatttggattatgagaaggaagaggtagaagcccagccaaggcagtggaag
aaatatgacttccactatgacaatgtgctctgggccttgctgactctgtttacggtgtcc
acaggagaggggtggcccatggtgctgaaacactctgtggacgccacctatgaggagcag
gggccaagccccgggtttcggatggagctttccatcttctatgtggtctactttgtggtc
ttcccttttttctttgtcaacatctttgtggccttgatcatcatcaccttccaggagcag
ggggacaaggtgatgtctgagtgcagtctggaaaagaatgagagggcttgcattgacttt
gccatcagcgccaaacccctgacacggtacatgcctcagaacaagcagtcgttccagtat
aagacatggacatttgtggtctctccaccctttgagtacttcattatggccatgatagcc
ctcaacacagtggtgctgatgatgaagttctacgatgccccttatgagtacgagctgatg
ctgaagtgcttgaacatcgtcttcacatccatgttctctctggagtgcatcctgaagatc
atcgccttcggggtgttgaactacttcagagatgcctggaacgtctttgactttgtcact
gttttgggaagtattactgatattttagtaacggagattgcggaaacgaacaacttcatc
aacttgagcttccttcgcctcttccgggcagcacggctgatcaagctgcttcgccagggc
tacaccatccgcatcttgttatggacctttgtccagtcctttaaggcgctgccctacgtg
tgcctcctcattgccatgctgttcttcatctacgccatcatcggcatgcaggtttttgga
aacattgcccttgatgatggcaccagcatcaaccgacacaacaacttccggacatttctg
caagccttaatgctgttgttcaggagtgccactggggaggcctggcacgaaatcatgctg
tcttgcctgggcaaccgggcctgcgacccacatgccaacgccagcgaatgcgggagcgac
tttgcctatttttattttgtctccttcatcttcctctgttcctttctgatgctgaacctc
tttgttgctgtgatcatggacaatttcgaatacctcacgcgggattcttccatcctaggg
ccgcaccacctcgatgaattcattcgcgtctgggctgaatacgacccagctgcgtgtggg
cgcatcagttacaatgacatgtttgagatgctgaaacacatgtccccacctctgggtttg
gggaagaaatgcccggctcgagttgcatacaagcgcctggttcgaatgaacatgcccata
tccaatgaggacatgacggtacactttacatccacactgatggccctcatccggacggca
ctggagatcaagcttgccccagcggggacaaaacagcaccaatgtgatgctgagctgagg
aaggagatctcttctgtgtgggctaatctgccccagaagactctggacttactggtgcca
ccccacaaacctgacgagatgacagtggggaaggtctatgcggctctcatgatatttgac
ttctacaaacagaacaaaaccaccagagatcagactcaccaagctcctggaggcctgtcc
cagatgggtcctgtttccctgttccatcctctgaaggccaccctggagcagacacagccc
gctgtgctccgaggagctcgggttttccttcgacaaaagagtgcaacttccctcagcaat
gggggcgccatacaaacccaggaaagtggcatcaaggagtccctgtcctggggcacgcag
aggacccaggacgtactttatgaggccagagcacctctagaacgtggccattctgcagag
atccctgtggggcagccaggagcactggctgtagatgtccagatgcagaacatgacattg
agaggaccggatggggagccccagcctggcctggagagccaaggccgagcggcctctatg
ccacgcctggcggcagaaacacagccggcccctaatgccagccccatgaagcgctccatc
tccacactggctccacgcccgcatgggactcagctttgcaacacagtcctggaccggcca
cctcctagccaggtgtcccatcaccaccaccaccgctgccaccggcgcagggacaagaag
cagaggtccctggaaaaggggcccagcctgtctgttgacacagaaggtgcaccaagtact
gctgcaggatctggcctgccccatggagaagggtccacaggctgccggcgggagcgtaag
caagagcgaggccggtcccaggagcggaggcagccctcctcctcttcttcagagaagcag
cgcttctattcctgtgaccgctttgggagccgggagcccccacaacctaagccctccctc
agtagccaccccatatcgccaacagcggcactagagccaggaccccacccgcagggcagt
ggttccgttaatgggagccccttgatgtcaacatctggtgctagcacgccgggccgaggt
gggcggaggcagctcccccagactcccctgaccccacgccccagcatcacctacaagacg
gccaattcctcgcctgtccactttgctgagggtcagagtggccttccagccttctcccct
ggccgtctcagccgcggcctttctgaacacaatgccctgctccagaaagagcccctgagc
cagcctctagcttctggctcccgcattggctctgacccttacctagggcagcgtctggac
agtgaggcctctgcccacaacctgcctgaggatacactcacctttgaagaggccgtggcc
accaactctggccgctcctccaggacttcctatgtgtcctccctcacttcccaatcccac
cctctccgccgtgtacccaatggctaccactgcactttgggactcagcaccggcgtccgg
gcgcggcacagctaccaccacccagaccaggatcactggtgctag

KEGG   Rattus norvegicus (rat): 29716
Entry
29716             CDS       T01003                                 

Gene name
Cacna1d
Definition
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1D
  KO
K04851  voltage-dependent calcium channel L type alpha-1D
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04022  cGMP-PKG signaling pathway
rno04024  cAMP signaling pathway
rno04218  Cellular senescence
rno04260  Cardiac muscle contraction
rno04261  Adrenergic signaling in cardiomyocytes
rno04270  Vascular smooth muscle contraction
rno04530  Tight junction
rno04713  Circadian entrainment
rno04723  Retrograde endocannabinoid signaling
rno04724  Glutamatergic synapse
rno04725  Cholinergic synapse
rno04726  Serotonergic synapse
rno04727  GABAergic synapse
rno04728  Dopaminergic synapse
rno04911  Insulin secretion
rno04912  GnRH signaling pathway
rno04921  Oxytocin signaling pathway
rno04924  Renin secretion
rno04925  Aldosterone synthesis and secretion
rno04927  Cortisol synthesis and secretion
rno04929  GnRH secretion
rno04930  Type II diabetes mellitus
rno04934  Cushing syndrome
rno04935  Growth hormone synthesis, secretion and action
rno04973  Carbohydrate digestion and absorption
rno05010  Alzheimer disease
rno05020  Prion disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05031  Amphetamine addiction
rno05410  Hypertrophic cardiomyopathy
rno05412  Arrhythmogenic right ventricular cardiomyopathy
rno05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    29716 (Cacna1d)
   04020 Calcium signaling pathway
    29716 (Cacna1d)
   04024 cAMP signaling pathway
    29716 (Cacna1d)
   04022 cGMP-PKG signaling pathway
    29716 (Cacna1d)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    29716 (Cacna1d)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    29716 (Cacna1d)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    29716 (Cacna1d)
   04929 GnRH secretion
    29716 (Cacna1d)
   04912 GnRH signaling pathway
    29716 (Cacna1d)
   04921 Oxytocin signaling pathway
    29716 (Cacna1d)
   04935 Growth hormone synthesis, secretion and action
    29716 (Cacna1d)
   04924 Renin secretion
    29716 (Cacna1d)
   04925 Aldosterone synthesis and secretion
    29716 (Cacna1d)
   04927 Cortisol synthesis and secretion
    29716 (Cacna1d)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    29716 (Cacna1d)
   04261 Adrenergic signaling in cardiomyocytes
    29716 (Cacna1d)
   04270 Vascular smooth muscle contraction
    29716 (Cacna1d)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    29716 (Cacna1d)
  09156 Nervous system
   04724 Glutamatergic synapse
    29716 (Cacna1d)
   04727 GABAergic synapse
    29716 (Cacna1d)
   04725 Cholinergic synapse
    29716 (Cacna1d)
   04728 Dopaminergic synapse
    29716 (Cacna1d)
   04726 Serotonergic synapse
    29716 (Cacna1d)
   04723 Retrograde endocannabinoid signaling
    29716 (Cacna1d)
  09159 Environmental adaptation
   04713 Circadian entrainment
    29716 (Cacna1d)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    29716 (Cacna1d)
   05020 Prion disease
    29716 (Cacna1d)
   05022 Pathways of neurodegeneration - multiple diseases
    29716 (Cacna1d)
  09165 Substance dependence
   05031 Amphetamine addiction
    29716 (Cacna1d)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    29716 (Cacna1d)
   05412 Arrhythmogenic right ventricular cardiomyopathy
    29716 (Cacna1d)
   05414 Dilated cardiomyopathy
    29716 (Cacna1d)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    29716 (Cacna1d)
   04934 Cushing syndrome
    29716 (Cacna1d)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    29716 (Cacna1d)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   29716 (Cacna1d)
SSDB
Motif
Pfam: Ion_trans CAC1F_C Ca_chan_IQ GPHH PKD_channel Rer1
Other DBs
NCBI-GeneID: 29716
NCBI-ProteinID: NP_001376154
RGD: 70973
Ensembl: ENSRNOG00000013147
LinkDB
Structure
PDB: 
1VYT

Position
16
AA seq 2164 aa
MMMMMMMKKMQHQRQQQEDHANEANYARGTRLPISGEGPTSQPNSSKQTVLSWQAAIDAA
RQAKAAQTMSTSAPPPVGSLSQRKRQQYAKSKKQGNSSNSRPARALFCLSLNNPIRRACI
SIVDWKPFDIFILLAIFANCVALAIYIPFPEDDSNSTNHNLEKVEYAFLIIFTVETFLKI
IAYGLLLHPNAYVRNGWNLLDFVIVIVGLFSVILEQLTKETEGGNHSSGKSGGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFIGKMHKT
CFFADSDIVAEEDPAPCAFSGNGRQCAANGTECRSGWVGPNGGITNFDNFAFAMLTVFQC
ITMEGWTDVLYWVNDAIGWEWPWVYFVSLIILGSFFVLNLVLGVLSGEFSKEREKAKARG
DFQKLREKQQLEEDLKGYLDWITQAEDIDPENEEEGGEEGKRNTSMPTSETESVNTENVS
GEGETQGCCGSLWCWWKRRGAAKTGPSGCRRWGQAISKSKLSRRWRRWNRFNRRRCRAAV
KSVTFYWLVIVLVFLNTLTISSEHYNQPDWLTQIQDIANKVLLALFTCEMLVKMYSLGLQ
AYFVSLFNRFDCFVVCGGITETILVELELMSPLGVSVFRCVRLLRIFKVTRHWTSLSNLV
ASLLNSMKSIASLLLLLFLFIIIFSLLGMQLFGGKFNFDETQTKRSTFDNFPQALLTVFQ
ILTGEDWNAVMYDGIMAYGGPSSSGMIVCIYFIILFICGNYILLNVFLAIAVDNLADAES
LNTAQKEEAEEKERKKIARKESLENKKNNKPEVNQIANSDNKVTIDDYQEEAEDKDPYPP
CDVPVGEEEEEEEEDEPEVPAGPRPRRISELNMKEKIAPIPEGSAFFILSKTNPIRVGCH
KLINHHIFTNLILVFIMLSSAALAAEDPIRSHSFRNTILGYFDYAFTAIFTVEILLKMTT
FGAFLHKGAFCRNYFNLLDMLVVGVSLVSFGIQSSAISVVKILRVLRVLRPLRAINRAKG
LKHVVQCVFVAIRTIGNIMIVTTLLQFMFACIGVQLFKGKFYRCTDEAKSNPEECRGLFI
LYKDGDVDSPVVRERIWQNSDFNFDNVLSAMMALFTVSTFEGWPALLYKAIDSNGENVGP
VYNYRVEISIFFIIYIIIVAFFMMNIFVGFVIVTFQEQGEKEYKNCELDKNQRQCVEYAL
KARPLRRYIPKNPYQYKFWYVVNSSPFEYMMFVLIMLNTLCLAMQHYEQSKMFNDAMDIL
NMVFTGVFTVEMVLKVIAFKPKGYFSDAWNTFDSLIVIGSIIDVALSEADNSEESNRISI
TFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIAMLFFIYAVIGMQMFGKV
AMRDNNQINRNNNFQTFPQAVLLLFRCATGEAWQEIMLACLPGKLCDPDSDYNPGEEYTC
GSNFAIVYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWSEYDPE
AKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVAMNMPLNSDGTVMFNATLFALVR
TALKIKTEGNLEQANEELRAVIKKIWKKTSMKLLDQVVPPAGDDEVTVGKFYATFLIQDY
FRKFKKRKEQGLVGKYPAKNTTIALQAGLRTLHDIGPEIRRAISCDLQDDEPEDSKPEEE
DVFKRNGALLGNYVNHVNSDRRESLQQTNTTHRPLHVQRPSIPPASDTEKPLFPPAGNSV
CHNHHNHNSIGKQVPTSTNANLNNANMSKAAHGKRPSIGDLEHVSENGHYSYKHDRELQR
RSSIKRTRYYETYIRSESGDEQLPTICREDPEIHGYFRDPRCFGEQEYFSSEECCEDDSS
PTWSRQNYSYYNRYPGSSMDFERPRGYHHPQGFLEDDDSPIGYDSRRSPRRRLLPPTPPS
HRRSSFNFECLRRQNSQDDVLPSPALPHRAALPLHLMQQQIMAVAGLDSSKAQKYSPSHS
TRSWATPPATPPYRDWTPCYTPLIQVDRSESMDQVNGSLPSLHRSSWYTDEPDISYRTFT
PASLTVPSSFRNKNSDKQRSADSLVEAVLISEGLGRYARDPKFVSATKHEIADACDLTID
EMESAASTLLNGSVCPRANGDMGPISHRQDYELQDFGPGYSDEEPDPGREEEDLADEMIC
ITTL
NT seq 6495 nt   +upstreamnt  +downstreamnt
atgatgatgatgatgatgatgaaaaaaatgcagcatcaacggcagcagcaagaggaccac
gcgaacgaggcaaactatgcaagaggcaccagactccctatttctggtgaaggaccaact
tctcagccgaacagctccaagcaaaccgtcctgtcttggcaagctgcaattgatgctgct
agacaggccaaggccgcccagaccatgagcacgtctgcacccccacctgtaggatctctc
tcccaaagaaaacgtcagcaatacgccaagagcaaaaaacagggtaactcgtctaacagc
cgacctgcccgtgccctcttctgtttatccctcaataaccccatccgaagagcctgcatt
agtatagtggattggaaaccatttgacatatttatattattggctatttttgccaattgt
gtggccttagctatttacatcccgttccctgaagatgattctaattcaacaaatcataac
ttggaaaaagtagaatatgccttcctgattatttttacagtggagacatttctgaagatt
atagcgtacggactgctgctgcatcctaatgcttacgttaggaacggatggaacttactg
gattttgttatagtaatagtaggattgtttagtgtaattttggaacaattaaccaaagaa
acagaaggcgggaaccactctagtggcaaatcaggaggctttgatgtcaaagccctccgt
gccttccgagtgttaagaccgcttcgacttgtatcaggagtgcccagtttacaagttgtt
ctgaactccattataaaagccatggtccccctcctccacatagcccttttggtgttattc
gtaattatcatctatgcgattatagggttggaactttttattggaaaaatgcacaaaacc
tgtttttttgctgactcagatatagtagctgaagaggacccagctccatgcgcgttctca
gggaatggacgccagtgtgccgccaatggcacggaatgtaggagcggctgggtcggcccc
aatggaggcatcactaattttgacaactttgcctttgccatgctcactgtgttccagtgc
atcaccatggagggctggacagatgtgctctactgggttaatgatgcgataggatgggag
tggccatgggtgtattttgttagtctgatcatccttggctcatttttcgtccttaacctg
gttcttggtgtccttagtggagaattctcaaaggaaagagagaaggctaaagcacgtgga
gatttccagaagcttcgggagaagcagcagctggaagaggatctcaagggctacttggac
tggatcacccaggcagaagacatagatcctgagaatgaagaggagggtggagaggagggc
aaacgaaacactagcatgcccaccagtgagaccgaatctgtgaacacagagaacgtaagt
ggtgaaggcgagacccagggatgctgtggaagtctctggtgctggtggaaaagaagaggc
gcggccaagactgggccctctgggtgtcggcggtggggccaagccatctcaaaatccaag
ctcagccgtcggtggcgtcgctggaaccggttcaatcgcaggagatgcagggcagctgtg
aagtctgtcacgttttactggctggtgatcgttctggtgtttctcaacactctgacgatt
tcctctgagcattacaatcagccagactggctgacgcagattcaagatatagcgaacaaa
gtgctcttggctttgttcacctgtgagatgctggtgaagatgtacagcctgggcctccag
gcctacttcgtctctctcttcaaccgcttcgattgctttgtggtgtgtgggggaatcacc
gaaaccatcctggtggaactggagctcatgtctcccctgggcgtctctgtgttccggtgt
gtacgtctcctgaggatcttcaaagtgaccaggcactggacttccctgagcaacttggtg
gcgtccctgttaaactccatgaagtccatcgcctctctgctgttgctgctcttcctcttc
atcatcatcttctccctgctgggaatgcagctgttcggagggaagttcaatttcgatgag
acacagaccaagcgaagcaccttcgacaacttcccacaggcgctcctgactgtgttccag
atcctgacgggcgaagactggaatgcggtgatgtatgacggcatcatggcctacggaggc
ccgtcctcctctggaatgattgtctgtatttacttcatcatccttttcatctgtggtaac
tatatcctgctgaacgtcttcttggccattgctgtagacaatttggctgatgctgaaagt
ctgaacactgctcagaaagaggaagccgaagaaaaagaaaggaaaaaaattgccagaaaa
gaaagcctagaaaacaaaaaaaacaacaaaccagaggtcaaccagatagccaacagtgac
aacaaggttactattgatgactatcaagaggaggctgaagataaggacccttatccaccc
tgcgatgtgccagtaggtgaagaggaagaggaggaggaagaggacgagcctgaggttcct
gctggtccccgtcctcgaagaatctcagagttgaacatgaaggagaaaattgcacccatc
cccgaaggaagcgcattcttcattcttagcaagaccaacccgatccgtgtgggttgccac
aaactcatcaaccaccacatcttcaccaacctcatcctggtcttcatcatgctgagcagc
gctgccctggccgcagaggatcccatccgcagccactccttccgcaacactatactgggc
tactttgactatgctttcacagccatctttacggttgaaatcctgttaaagatgacaact
tttggagcgttcttgcacaaaggggctttctgtaggaactacttcaatttgctggacatg
ctggtcgttggggtgtctctggtgtcatttgggattcaatccagtgccatctcggttgtg
aagattctgagggtcttaagggtcttgaggcctctcagagcaatcaacagagcaaaagga
cttaagcacgtggtccagtgtgtctttgtggccatccgaaccatcggcaacatcatgatc
gtcacgaccctgctccagttcatgtttgcttgcattggggtccagctgttcaaggggaag
ttctaccgttgcacagatgaggccaaaagtaaccccgaggagtgcagggggcttttcatc
ctttataaggacggcgatgtcgacagtcccgtggtccgtgagaggatctggcaaaacagt
gatttcaatttcgacaatgtcctttcggctatgatggcgctcttcacggtctcgactttt
gagggctggcccgcgttgctgtacaaagctatcgactcaaacggagagaacgttggtcct
gtctacaactaccgtgtggagatctccatcttcttcattatctacatcatcatcgtggcc
ttcttcatgatgaatatcttcgtgggcttcgtcatcgtcaccttccaggagcagggagaa
aaggagtataagaactgtgagctggacaaaaatcagcgtcagtgtgtggaatatgccttg
aaggcccgccccttaaggagatacatccccaaaaacccataccagtacaagttctggtac
gtggtgaactcctcgcctttcgaatatatgatgtttgtcctcatcatgctcaacacgctc
tgcctggccatgcagcactatgagcaatccaagatgttcaatgacgccatggacattctg
aacatggtcttcacgggggtcttcaccgttgagatggttttgaaagtcatcgcatttaag
cccaaggggtattttagtgacgcctggaacacgtttgactccctcatcgtaatcggcagc
attatagacgtggcactcagcgaagctgacaactctgaagagagcaatagaatctccatc
acctttttccgtcttttccgagtgatgcggttggtgaagcttctcagcagaggggaaggc
atccggactctgctatggaccttcattaagtccttccaggcactcccatatgtcgccctc
ctcattgccatgctcttcttcatctacgccgtcattggcatgcagatgtttgggaaggtt
gccatgagagataacaaccagatcaataggaacaacaacttccagacgtttccccaggca
gtgctgctgctcttcaggtgtgcaacaggggaggcctggcaggagatcatgctcgcctgc
ctccctgggaagctgtgtgacccggactcagattacaacccaggagaggaatatacttgt
gggagcaactttgccattgtctacttcatcagcttttacatgctctgtgcgttcctgatc
atcaacctcttcgtggctgtcatcatggacaattttgactatctgacgagggactggtct
attctggggcctcaccacttggacgaattcaaaagaatatggtctgaatatgaccccgag
gcaaagggaaggataaaacaccttgatgtggtcactttgctccgacgtatccagcctccc
ctgggatttggaaagttgtgtccacaccgagtggcgtgtaagagattggtcgccatgaac
atgcctctcaacagtgatgggacagtcatgttcaatgcaactctgtttgctttggtacgg
acggctctcaagatcaagactgaaggcaacctggagcaagctaatgaagagctccgcgct
gtgataaagaaaatctggaagaagacaagcatgaagctacttgaccaagttgtccctcca
gctggtgatgatgaggtaaccgtggggaagttctatgccactttcctgatacaggactac
tttaggaaattcaagaagcggaaagagcaaggcctggtggggaaataccctgcgaagaac
accacgatcgccctacaggcgggattaaggaccctgcatgacattgggccagaaatccga
cgggctatatcctgtgacttgcaagatgacgaaccagaagactccaaaccagaagaggaa
gatgtattcaaaagaaatggtgccctgcttggaaactatgtcaatcatgttaatagtgat
aggagagagtcccttcagcagaccaataccacccaccgtcccctgcatgtccaaaggcct
tcaattccacctgcaagtgatactgagaaaccgctgtttcctccagcaggaaattcggtg
tgtcataaccatcataaccataattccatagggaagcaagttcccacctccacaaatgcc
aatctcaataacgccaatatgtccaaagctgcccacggaaagcggcccagcattggggac
cttgagcatgtgtctgaaaacggccattactcctacaagcacgaccgagagcttcaaaga
aggtccagtattaaaagaacccgctattatgaaacttacattaggtctgagtcaggagac
gagcagcttccaaccatttgccgtgaagaccctgagatacacggctacttccgagacccc
cgctgcttcggggagcaggaatatttcagtagcgaggagtgctgtgaggatgacagttct
cccacctggagcaggcaaaactacagctattacaacaggtacccaggcagctccatggac
tttgagaggccccgaggctaccatcacccccaaggtttcttagaagatgacgactctccc
attggctatgactcacggagatctccaagaagacgccttctacctcctaccccaccatcc
catcggaggtcctccttcaactttgagtgtctgcgcaggcaaaacagccaagatgacgtc
cttccgtcgcctgccctgcctcaccgcgctgccctgcccctgcaccttatgcagcagcag
atcatggccgttgcaggcctagattccagtaaagcccagaagtactcgccgagccactct
acccggtcatgggccacccctccagcaacccctccgtaccgagactggaccccatgctac
acccctttgatccaggtggatcgctcagagtctatggaccaggtcaatggcagcctgccg
tcgctacaccgcagttcctggtatacagatgaacccgacatctcctataggactttcaca
ccggccagcctgaccgtccccagcagcttccggaacaaaaacagcgacaagcagaggagt
gcagacagcctggtggaagcagtcctgatatccgaaggcttgggacgctacgcaagggac
ccaaaatttgtctcagcaacaaaacatgagatcgccgatgcctgtgacctaaccatagac
gagatggagagcgcggccagcaccctgctcaatggaagcgtgtgtcctcgagccaacggg
gacatgggccccatctcacaccgccaggactatgagctccaggactttggtcctggctac
agtgacgaggaaccagaccctgggcgagaggaagaggacctggcagatgaaatgatttgc
atcaccaccttgtag

KEGG   Rattus norvegicus (rat): 29717
Entry
29717             CDS       T01003                                 

Gene name
Cacna1g
Definition
(RefSeq) voltage-dependent T-type calcium channel subunit alpha-1G isoform 1
  KO
K04854  voltage-dependent calcium channel T type alpha-1G
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04713  Circadian entrainment
rno04925  Aldosterone synthesis and secretion
rno04927  Cortisol synthesis and secretion
rno04929  GnRH secretion
rno04930  Type II diabetes mellitus
rno04934  Cushing syndrome
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    29717 (Cacna1g)
   04020 Calcium signaling pathway
    29717 (Cacna1g)
 09150 Organismal Systems
  09152 Endocrine system
   04929 GnRH secretion
    29717 (Cacna1g)
   04925 Aldosterone synthesis and secretion
    29717 (Cacna1g)
   04927 Cortisol synthesis and secretion
    29717 (Cacna1g)
  09159 Environmental adaptation
   04713 Circadian entrainment
    29717 (Cacna1g)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    29717 (Cacna1g)
   04934 Cushing syndrome
    29717 (Cacna1g)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    29717 (Cacna1g)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   29717 (Cacna1g)
SSDB
Motif
Pfam: Ion_trans PKD_channel SieB
Other DBs
NCBI-GeneID: 29717
NCBI-ProteinID: NP_001295231
RGD: 68942
Ensembl: ENSRNOG00000060528
LinkDB
Position
10
AA seq 2289 aa
MDEEEDGAGAEESGQPRSFTQLNDLSGAGGRQGPGSTEKDPGSADSEAEGLPYPALAPVV
FFYLSQDSRPRSWCLRTVCNPWFERVSMLVILLNCVTLGMFRPCEDIACDSQRCRILQAF
DDFIFAFFAVEMVVKMVALGIFGKKCYLGDTWNRLDFFIVIAGMLEYSLDLQNVSFSAVR
TVRVLRPLRAINRVPSMRILVTLLLDTLPMLGNVLLLCFFVFFIFGIVGVQLWAGLLRNR
CFLPENFSLPLSVDLEPYYQTENEDESPFICSQPRENGMRSCRSVPTLRGEGGGGPPCSL
DYETYNSSSNTTCVNWNQYYTNCSAGEHNPFKGAINFDNIGYAWIAIFQVITLEGWVDIM
YFVMDAHSFYNFIYFILLIIVGSFFMINLCLVVIATQFSETKQRESQLMREQRVRFLSNA
STLASFSEPGSCYEELLKYLVYILRKAARRLAQVSRAIGVRAGLLSSPVARSGQEPQPSG
SCTRSHRRLSVHHLVHHHHHHHHHYHLGNGTLRVPRASPEIQDRDANGSRRLMLPPPSTP
TPSGGPPRGAESVHSFYHADCHLEPVRCQAPPPRCPSEASGRTVGSGKVYPTVHTSPPPE
ILKDKALVEVAPSPGPPTLTSFNIPPGPFSSMHKLLETQSTGACHSSCKISSPCSKADSG
ACGPDSCPYCARTGAGEPESADHVMPDSDSEAVYEFTQDAQHSDLRDPHSRRRQRSLGPD
AEPSSVLAFWRLICDTFRKIVDSKYFGRGIMIAILVNTLSMGIEYHEQPEELTNALEISN
IVFTSLFALEMLLKLLVYGPFGYIKNPYNIFDGVIVVISVWEIVGQQGGGLSVLRTFRLM
RVLKLVRFLPALQRQLVVLMKTMDNVATFCMLLMLFIFIFSILGMHLFGCKFASERDGDT
LPDRKNFDSLLWAIVTVFQILTQEDWNKVLYNGMASTSSWAALYFIALMTFGNYVLFNLL
VAILVEGFQAEEIGKREDASGQLSCIQLPVNSQGGDATKSESEPDFFSPSVDGDGDRKKR
LALVALGEHAELRKSLLPPLIIHTAATPMSLPKSSSTGVGEALGSGSRRTSSSGSAEPGA
AHHEMKSPPSARSSPHSPWSAASSWTSRRSSRNSLGRAPSLKRRSPSGERRSLLSGEGQE
SQDEEESSEEDRASPAGSDHRHRGSLEREAKSSFDLPDTLQVPGLHRTASGRSSASEHQD
CNGKSASGRLARTLRTDDPQLDGDDDNDEGNLSKGERIQAWVRSRLPACCRERDSWSAYI
FPPQSRFRLLCHRIITHKMFDHVVLVIIFLNCITIAMERPKIDPHSAERIFLTLSNYIFT
AVFLAEMTVKVVALGWCFGEQAYLRSSWNVLDGLLVLISVIDILVSMVSDSGTKILGMLR
VLRLLRTLRPLRVISRAQGLKLVVETLMSSLKPIGNIVVICCAFFIIFGILGVQLFKGKF
FVCQGEDTRNITNKSDCAEASYRWVRHKYNFDNLGQALMSLFVLASKDGWVDIMYDGLDA
VGVDQQPIMNHNPWMLLYFISFLLIVAFFVLNMFVGVVVENFHKCRQHQEEEEARRREEK
RLRRLEKKRRNLMLDDVIASGSSASAASEAQCKPYYSDYSRFRLLVHHLCTSHYLDLFIT
GVIGLNVVTMAMEHYQQPQILDEALKICNYIFTVIFCPLSQFSNLWAFGFRRFFQDRWNQ
LDLAIVLLSIMGITLEEIEVNASLPINPTIIRIMRVLRIARVLKLLKMAVGMRALLDTVM
QALPQVGNLGLLFMLLFFIFAALGVELFGDLECDETHPCEGLGRHATFRNFGMAFLTLFR
VSTGDNWNGIMKDTLRDCDQESTCYNTVISPIYFVSFVLTAQFVLVNVVIAVLMKHLEES
NKEAKEEAELEAELELEMKTLSPQPHSPLGSPFLWPGVEGVNSPDSPKPGAPHTTAHIGA
ASGFSLEHPTMVPHPEEVPVPLGPDLLTVRKSGVSRTHSLPNDSYMCRNGSTAERSLGHR
GWGLPKAQSGSILSVHSQPADTSCILQLPKDVHYLLQPHGAPTWGAIPKLPPPGRSPLAQ
RPLRRQAAIRTDSLDVQGLGSREDLLSEVSGPSCPLTRSSSFWGGSSIQVQQRSGIQSKV
SKHIRLPAPCPGLEPSWAKDPPETRSSLELDTELSWISGDLLPSSQEEPLSPRDLKKCYS
VETQSCRRRPGSWLDEQRRHSIAVSCLDSGSQPRLCPSPSSLGGQPLGGPGSRPKKKLSP
PSISIDPPESQGSRPPCSPGVCLRRRAPASDSKDPSVSSPLDSTAASPSPKKDTLSLSGL
SSDPTDMDP
NT seq 6870 nt   +upstreamnt  +downstreamnt
atggacgaggaggaggatggagcgggcgccgaggagtcgggacagccccgtagcttcacg
cagctcaacgacctgtccggggccgggggccggcaggggccggggtcgacggaaaaggac
ccgggcagcgcggactccgaggcggaggggctgccgtacccggcgctagccccggtggtt
ttcttctacttgagccaggacagccgcccgcggagctggtgtctccgcacggtctgtaac
ccgtggttcgagcgagtcagtatgctggtcattcttctcaactgtgtgactctgggtatg
ttcaggccgtgtgaggacattgcctgtgactcccagcgctgccggatcctgcaggccttc
gatgacttcatctttgccttctttgctgtggaaatggtggtgaagatggtggccttgggc
atctttgggaagaaatgttacctgggagacacttggaaccggcttgactttttcattgtc
attgcagggatgctggagtattcgctggacctgcagaacgtcagcttctccgcagtcagg
acagtccgtgtgctgcgaccgctcagggccattaaccgggtgcccagcatgcgcattctc
gtcacattactgctggacaccttgcctatgctgggcaacgtcctgctgctctgtttcttc
gtctttttcatctttggcatcgtgggcgtccagctgtgggcaggactgcttcgcaaccga
tgcttcctccccgagaacttcagcctccccctgagcgtggacctggagccttattaccag
acagagaatgaggacgagagccccttcatctgctctcagcctcgggagaatggcatgaga
tcctgcaggagtgtgcccacactgcgtggggaaggcggtggtggcccaccctgcagtctg
gactatgagacctataacagttccagcaacaccacctgtgtcaactggaaccagtactat
accaactgctctgcgggcgagcacaaccccttcaaaggcgccatcaactttgacaacatt
ggctatgcctggatcgccatcttccaggtcatcacactggagggctgggtcgacatcatg
tacttcgtaatggacgctcactccttctacaacttcatctacttcattcttctcatcatc
gtgggctccttcttcatgatcaacctgtgcctggtggtgattgccacgcagttctccgag
accaaacagcgggagagtcagctgatgcgggagcagcgtgtacgattcctgtccaatgct
agcaccctggcaagcttctctgagccaggcagctgctatgaggagctactcaagtacctg
gtgtacatcctccgaaaagcagcccgaaggctggcccaggtctctagggctataggcgtg
cgggctgggctgctcagcagcccagtggcccgtagtgggcaggagccccagcccagtggc
agctgcactcgctcacaccgtcgtctgtctgtccaccacctggtccaccaccatcaccac
caccatcaccactaccacctgggtaatgggacgctcagagttccccgggccagcccagag
atccaggacagggatgccaatgggtctcgccggctcatgctaccaccaccctctacaccc
actccctctgggggccctccgaggggtgcggagtctgtacacagcttctaccatgctgac
tgccacttggagccagtccgttgccaggcaccccctcccagatgcccatcggaggcatct
ggtaggactgtgggtagtgggaaggtgtaccccactgtgcataccagccctccaccagag
atactgaaggataaagcactagtggaggtggcccccagccctgggccccccaccctcacc
agcttcaacatcccacctgggcccttcagctccatgcacaagctcctggagacacagagt
acgggagcctgccatagctcctgcaaaatctccagcccttgctccaaggcagacagtgga
gcctgcgggccggacagttgtccctactgtgcccggacaggagcaggagagccagagtcc
gctgaccatgtcatgcctgactcagacagcgaggctgtgtatgagttcacacaggacgct
cagcacagtgacctccgggatccccacagccggcggcgacagcggagcctgggcccagat
gcagagcctagttctgtgctggctttctggaggctgatctgtgacacattccggaagatc
gtagatagcaaatactttggccggggaatcatgatcgccatcctggtcaatacactcagc
atgggcatcgagtaccacgagcagcccgaggagctcaccaacgccctggaaatcagcaac
atcgtcttcaccagcctcttcgccttggagatgctgctgaaactgcttgtctacggtccc
tttggctacattaagaatccctacaacatctttgatggtgtcattgtggtcatcagtgtg
tgggagattgtgggccagcagggaggtggcctgtcggtgctgcggaccttccgcctgatg
cgggtgctgaagctggtgcgcttcctgccggccctgcagcgccagctcgtggtgctcatg
aagaccatggacaacgtggccaccttctgcatgctcctcatgctgttcatcttcatcttc
agcatcctgggcatgcatctctttggttgcaagttcgcatctgaacgggatggggacacg
ttgccagaccggaagaatttcgactccctgctctgggccatcgtcactgtctttcagatt
ctgactcaggaagactggaataaagtcctctacaacggcatggcctccacatcgtcttgg
gctgctctttacttcatcgccctcatgacttttggcaactatgtgctctttaacctgctg
gtggccattcttgtggaaggcttccaggcagaggaaatcggcaaacgggaagatgcgagt
ggacagttaagctgtattcagctgcctgtcaactctcaggggggagatgccaccaagtct
gagtcagagcctgatttcttttcgcccagtgtggatggtgatggggacagaaagaagcgc
ttggccctggtggctttgggagaacacgcggaactacgaaagagccttttgccacccctc
atcatccatacggctgcgacaccaatgtcactacccaagagctccagcacaggtgtgggg
gaagcactgggctctggctctcgacgtaccagtagcagtgggtccgctgagcctggagct
gcccaccatgagatgaaatctccgccaagtgcccgcagctccccgcacagtccctggagt
gcggcaagcagctggaccagcaggcgctccagcaggaacagcctgggccgggcccccagc
ctaaagcggaggagcccgagcggggagcggaggtccctgctgtctggagagggccaggag
agtcaggatgaggaggaaagttcagaagaggaccgggccagcccagcaggcagtgaccat
cgccacaggggttccttggaacgtgaggccaagagttcctttgacctgcctgacactctg
caggtgccggggctgcaccgcacagccagcggccggagctctgcctctgagcaccaagac
tgtaatggcaagtcggcttcagggcgtttggcccgcaccctgaggactgatgacccccaa
ctggatggggatgatgacaatgatgagggaaatctgagcaaaggggaacgcatacaagcc
tgggtcagatcccggcttcctgcctgttgccgagagcgagattcctggtcggcctatatc
tttcctcctcagtcaaggtttcgtctcctgtgtcaccggatcatcacccacaagatgttt
gaccatgtggtcctcgtcatcatcttcctcaactgtatcaccatcgctatggagcgcccc
aaaattgacccccacagcgctgagcgcatcttcctgaccctctccaactacatcttcacg
gcagtctttctagctgaaatgacagtgaaggtggtggcactgggctggtgctttggggag
caggcctacctgcgcagcagctggaatgtgctggacggcttgctggtgctcatctccgtc
atcgacatcctggtctccatggtctccgacagcggcaccaagatccttggcatgctgagg
gtgctgcggctgctgcggaccctgcgtccactcagggtcatcagccgggcccagggactg
aagctggtggtagagactctgatgtcatccctcaaacccattggcaacattgtggtcatt
tgctgtgccttcttcatcatttttggaattctcggggtgcagctcttcaaagggaagttc
ttcgtgtgtcagggtgaggacaccaggaacatcactaacaaatccgactgcgctgaggcc
agctaccgatgggtccggcacaagtacaactttgacaacctgggccaggctctgatgtcc
ctgtttgtgctggcctccaaggatggttgggttgacatcatgtatgatgggctggatgct
gtgggtgtggatcagcagcccatcatgaaccacaacccctggatgctgctatacttcatc
tccttcctcctcatcgtggccttctttgtcctgaacatgtttgtgggcgtggtggtggag
aacttccataagtgcagacagcaccaggaggaggaggaggcgaggcggcgtgaggagaag
cgactacggaggctggagaaaaagagaaggaatctaatgttggacgatgtaattgcttcc
ggcagctcagccagcgctgcgtcagaagcccagtgcaagccctactactctgactactcg
agattccggctccttgtccaccacctgtgtaccagccactacctggacctcttcatcact
ggtgtcatcgggctgaacgtggtcactatggccatggaacattaccagcagccccagatc
ctggacgaggctctgaagatctgcaattacatctttaccgtcatcttttgtcctttgagt
cagttttcaaacttgtgggcctttggcttccgccgtttcttccaggacaggtggaaccag
ctggacctggctattgtgcttctgtccatcatgggcatcacactggaggagattgaggtc
aatgcttcgctgcccatcaaccccaccatcatccgtatcatgagggtgctccgcattgct
cgagttctgaagctgttgaagatggctgtgggcatgcgggcactgctggacacggtgatg
caggccctgccccaggtggggaacctgggacttctcttcatgttattgtttttcatcttt
gcagctctgggcgtggagctctttggagacctggagtgtgatgagacacacccttgtgag
ggcttgggtcggcatgccacctttaggaactttggtatggcctttctgaccctcttccga
gtctccactggtgacaactggaatggtattatgaaggacaccctccgggactgtgaccag
gagtccacctgctacaacactgtcatctcccctatctactttgtgtccttcgtgctgacg
gcccagtttgtgctggtcaacgtggtcatagctgtgctgatgaagcacctggaagaaagc
aacaaagaggccaaggaggaggccgagctcgaggccgagctggagctggagatgaagacg
ctcagcccgcagccccactccccgctgggcagccccttcctctggcccggggtggagggt
gtcaacagtcctgacagccctaagcctggggctccacacaccactgcccacattggagca
gcctcgggcttctcccttgagcaccccacgatggtaccccaccccgaggaggtgccagtc
cccctaggaccagacctgctgactgtgaggaagtctggtgtcagccggacgcactctctg
cccaatgacagctacatgtgccgcaatgggagcactgctgagagatccctaggacacagg
ggctgggggctccccaaagcccagtcaggctccatcttgtccgttcactcccaaccagca
gacaccagctgcatcctacagcttcccaaagatgtgcactatctgctccagcctcatggg
gcccccacctggggcgccatccctaaactacccccacctggccgctcccctctggctcag
aggcctctcaggcgccaggcagcaataaggactgactccctggatgtgcagggcctgggt
agccgggaagacctgttgtcagaggtgagtgggccctcctgccctctgacccggtcctca
tccttctggggcgggtcgagcatccaggtgcagcagcgttccggcatccagagcaaagtc
tccaagcacatccgcctgccagccccttgcccaggcctggaacccagctgggccaaggac
cctccagagaccagaagcagcttagagctggacacggagctgagctggatttcaggagac
ctccttcccagcagccaggaagaacccctgtccccacgggacctgaagaagtgctacagt
gtagagacccagagctgcaggcgcaggcctgggtcctggctagatgaacagcggagacac
tccattgctgtcagctgtctggacagcggctcccaaccccgcctatgtccaagcccctca
agcctcgggggccaacctcttgggggtcctgggagccggcctaagaaaaaactcagccca
cccagtatctctatagaccccccggagagccagggctctcggcccccatgcagtcctggt
gtctgcctcaggaggagggcgccggccagtgactctaaggatccctcggtctccagcccc
cttgacagcacggctgcctcaccctccccaaagaaagacacgctgagtctctctggtttg
tcttctgacccaacagacatggacccctga

KEGG   Rattus norvegicus (rat): 54234
Entry
54234             CDS       T01003                                 

Gene name
Cacna1e
Definition
(RefSeq) voltage-dependent R-type calcium channel subunit alpha-1E
  KO
K04852  voltage-dependent calcium channel R type alpha-1E
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04010  MAPK signaling pathway
rno04020  Calcium signaling pathway
rno04930  Type II diabetes mellitus
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    54234 (Cacna1e)
   04020 Calcium signaling pathway
    54234 (Cacna1e)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    54234 (Cacna1e)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04040 Ion channels [BR:rno04040]
    54234 (Cacna1e)
Ion channels [BR:rno04040]
 Voltage-gated cation channels
  Calcium channel, voltage-gated (Cav)
   54234 (Cacna1e)
SSDB
Motif
Pfam: Ion_trans Ca_chan_IQ GPHH PKD_channel
Other DBs
NCBI-GeneID: 54234
NCBI-ProteinID: NP_062167
RGD: 2246
Ensembl: ENSRNOG00000002863
UniProt: Q923K6
LinkDB
Structure
PDB: 
3DVK

Position
13
AA seq 2296 aa
MARFGEAVVVGRPGSGDGDSDQSRNRQGTPVPASGPAAAYKQSKAQRARTMALYNPIPVR
QNCFTVNRSLFIFGEDNIVRKYAKKLIDWPPFEYMILATIIANCIVLALEQHLPEDDKTP
MSRRLEKTEPYFIGIFCFEAGIKIVALGFIFHKGSYLRNGWNVMDFIVVLSGILATAGTH
FNTHVDLRTLRAVRVLRPLKLVSGIPSLQIVLKSIMKAMVPLLQIGLLLFFAILMFAIIG
LEFYSGKLHRACFMNNSGILEGFDPPHPCGVQGCPAGYECKDWIGPNDGITQFDNILFAV
LTVFQCITMEGWTTVLYNTNDALGATWNWLYFIPLIIIGSFFVLNLVLGVLSGEFAKERE
RVENRRAFMKLRRQQQIERELNGYRAWIDKAEEVMLAEENKNSGTSALEVLRRATIKRSR
TEAMTRDSSDEHCVDISSVGTPLARASIKSTKVDGASYFRHKERLLRISIRHMVKSQVFY
WIVLSVVALNTACVAIVHHNQPQWLTHLLYYAEFLFLGLFLLEMSLKMYGMGPRLYFHSS
FNCFDFGVTVGSIFEVVWAIFRPGTSFGISVLRALRLLRIFKITKYWASLRNLVVSLMSS
MKSIISLLFLLFLFIVVFALLGMQLFGGRFNFNDGTPSANFDTFPAAIMTVFQILTGEDW
NEVMYNGIRSQGGVSSGMWSAIYFIVLTLFGNYTLLNVFLAIAVDNLANAQELTKDEQEE
EEAFNQKHALQKAKEVSPMSAPNMPSIERERRRRHHMSVWEQRTSQLRRHMQMSSQEALN
KEEAPPMNPLNPLNPLSPLNPLNAHPSLYRRPRPIEGLALGLGLEKCEEERISRGGSLKG
DIGGLTSVLDNQRSPLSLGKREPPWLPRSCHGNCDPTQQETGGGETVVTFEDRARHRQSQ
RRSRHRRVRTEGKESASASRSRSASQERSLDEGVSIDGEKEHEPQSSHRSKEPTIHEEER
TQDLRRTNSLMVPRGSGLVGALDEAETPLVQPQPELEVGKDAALTEQEAEGSSEQALLAD
VQLDVGRGISQSEPDLSCMTTNMDKATTESTSVTVAIPDMDPLVDSTVVNISNKTDGEAS
PLKEAETKEEEEEVEKKKQKKEKRETGKAMVPHSSMFIFSTTNPIRKACHYIVNLRYFEM
CILLVIAASSIALAAEDPVLTNSERNKVLRYFDYVFTGVFTFEMVIKMIDQGLILQDGSY
FRDLWNILDFVVVVGALVAFALANALGTNKGRDIKTIKSLRVLRVLRPLKTIKRLPKLKA
VFDCVVTSLKNVFNILIVYKLFMFIFAVIAVQLFKGKFFYCTDSSKDTEKECIGNYVDHE
KNKMEVKGREWKRHEFHYDNIIWALLTLFTVSTGEGWPQVLQHSVDVTEEDRGPSRSNRM
EMSIFYVVYFVVFPFFFVNIFVALIIITFQEQGDKMMEECSLEKNERACIDFAISAKPLT
RYMPQNRHTFQYRVWHFVVSPSFEYTIMAMIALNTVVLMMKYYSAPWTYELALKYLNIAF
TMVFSLECVLKVIAFGFLNYFRDTWNIFDFITVIGSITEIILTDSKLVNTSGFNMSFLKL
FRAARLIKLLRQGYTIRILLWTFVQSFKALPYVCLLIAMLFFIYAIIGMQVFGNIKLDEE
SHINRHNNFRSFFGSLMLLFRSATGEAWQEIMLSCLGEKGCEPDTTAPSGQNESERCGTD
LAYVYFVSFIFFCSFLMLNLFVAVIMDNFEYLTRDSSILGPHHLDEFVRVWAEYDRAACG
RIHYTEMYEMLTLMSPPLGLGKRCPSKVAYKRLVLMNMPVAEDMTVHFTSTLMALIRTAL
DIKIAKGGADRQQLDSELQKETLAIWPHLSQKMLDLLVPMPKASDLTVGKIYAAMMIMDY
YKQSKVKKQRQQLEEQKNAPMFQRMEPSSLPQEIISNAKALPYLQQDPVSGLSGRSGYPS
MSPLSPQEIFQLACMDPADDGQFQEQQSLEPEVSELKSVQSSNHGIYLPPDTQEHAGSGR
ASSMPRLTMDPQVVTDPSSMRRSFSTIRDKRSNSSWLEEFSMERSSENTYKSRRRSYHSS
LRLSAHRLNSDSGHKSDTHRSGGRERGRSKERKHLLSPDVSRCNSEERGTQADWESPERR
QSRSPSEGRSQTPNRQGTGSLSESSIPSISDTSTPRRSRRQLPPVPPKPRPLLSYSSLMR
HTGGISPPPDGSEGGSPLASQALESNSACLTESSNSLHPQQGQHPSPQHYISEPYLALHE
DSHASDCGEEETLTFEAAVATSLGRSNTIGSAPPLRHSWQMPNGHYRRRRRGGPGPGMMC
GAVSDLLSDTEEDDKC
NT seq 6891 nt   +upstreamnt  +downstreamnt
atggctcgcttcggggaggcggtggtcgttggcagaccaggctcaggcgatggagactcg
gaccagagcaggaaccgacaaggaacccccgtaccggcctcggggccggcggccgcctac
aagcagtcaaaagcgcagagggcgcggactatggctttgtacaaccccataccagtccgg
cagaactgtttcacggtcaacagatccctgttcatcttcggagaagataacattgtcagg
aaatatgccaagaagctcatcgattggccgccatttgagtacatgatcctggccaccatc
attgccaactgcatcgtcttggccctggagcagcatcttcctgaggatgacaagacccca
atgtcccgaagactggagaagacagaaccatattttattggaatcttctgctttgaagct
gggatcaaaatcgtggctctaggattcatcttccataagggttcgtacctccgtaacggc
tggaatgtcatggacttcattgtggtcctcagtggcatcctggccactgcaggaacccat
ttcaacacccacgtggacctgcggaccctccgggctgtgcgtgtcctgaggcccttaaag
ctcgtgtcaggaatacctagcctgcagatcgtgctgaagtccatcatgaaggccatggtg
cctcttctgcagattggccttctgctcttctttgccattctcatgtttgccatcattggc
ttggagttctacagtggcaagttgcatcgagcatgcttcatgaacaattcaggtattcta
gagggatttgatcctcctcacccgtgtggtgtacagggctgcccggctggttatgaatgt
aaggactggatcggccccaatgacgggatcacccagtttgacaacatcctttttgctgtg
ctgactgtcttccaatgcatcactatggaagggtggaccactgtgctgtacaataccaat
gatgccttaggagccacctggaactggctgtacttcatccccctcatcatcatcggatcc
ttctttgttctcaaccttgtcctgggcgtgctttccggggaatttgccaaagaaagagag
agagtggagaaccgaagagcattcatgaagctccggcgtcagcaacagattgagcgcgag
ttgaatggctaccgcgcctggatagacaaagcagaggaagtcatgcttgctgaagaaaat
aaaaactcgggaacatcagccttggaagtgcttcgaagggcaaccatcaaaaggagccgg
acggaggccatgacccgagactccagcgatgagcactgcgttgatatctcttcagtgggc
acacctcttgccagagccagtatcaagagcacaaaagtagatggagcctcctatttccgg
cacaaggaacggcttctgcgtatctctatccgacacatggtcaagtcgcaagtgttctac
tggatcgtcctgagtgttgtggctctcaatactgcctgtgtggccatcgttcatcacaac
cagccacagtggctcactcacctcctctactatgcagaatttttgtttctgggactcttc
ctgttggagatgtccctgaagatgtatggcatggggccacgcctttattttcactcatcc
ttcaactgctttgattttggggtcacagtgggcagcatctttgaggtcgtttgggcaatc
ttccgacctggcacatcttttggaatcagtgtcttacgagctctccggctcctaaggata
tttaaaataaccaagtattgggcatccctccggaatctggttgtttccttgatgagctcc
atgaagtctatcatcagcttactcttcctcctcttcctcttcattgttgtctttgctctc
ctgggaatgcagctctttggaggcaggtttaactttaatgatgggactccttcggctaat
tttgataccttccctgcagctatcatgacagtgttccagatcctgacgggggaagactgg
aatgaagtgatgtataacggcatccgctcccagggtggggtgagctcaggcatgtggtct
gccatctacttcattgtgctcaccttgtttggaaactacacactgctgaatgtattcttg
gctatcgctgtggacaatctcgccaatgcccaggaactgaccaaggatgagcaggaggaa
gaagaagccttcaaccagaaacatgcactgcagaaggccaaggaggtcagcccgatgtct
gctcccaacatgccttccattgagagggagaggagacgccgacaccacatgtctgtgtgg
gaacagcgcaccagccagctgaggaggcacatgcaaatgtctagccaagaagccctcaac
aaagaggaggccccaccaatgaaccccctcaatccactcaacccactgagtcctctcaac
ccactcaatgctcatcctagcctctatcggaggcccaggcccattgagggcctagccctg
ggcttgggtcttgaaaaatgtgaagaggagcgtatcagccgtggaggttctctcaagggg
gacataggtggcctgactagcgtcctggacaaccagaggagccctttgtccctgggcaaa
cgggagccaccgtggctgcccagatcctgtcatggaaactgtgacccaacccagcaggag
actgggggaggagagactgtggtgacttttgaggaccgggccaggcacaggcagagtcag
aggcgaagccggcatcgccgagtcaggactgagggcaaggagtctgcctctgcctccaga
agcaggtctgccagccaggagcggagtctggatgaaggggtgtccatcgatggggagaag
gaacacgagcctcagagcagccacaggagcaaggagccaaccatccatgaagaagagaga
actcaggacttaaggaggaccaacagtctgatggtccccaggggctcaggactggtagga
gctcttgatgaggcagaaacacctctagtccagccccaacctgagctggaagtggggaag
gatgcagctctgacagagcaggaggctgaaggcagcagcgagcaagccctgcttgcggat
gtacagctggatgtgggccggggcattagccagagtgaacctgacctctcctgcatgaca
accaacatggacaaggctaccactgagagcaccagtgtcacagtcgccatccctgacatg
gaccccttggtggactcaacagtggtgaacattagcaacaagacggatggagaagccagt
cccttgaaggaagcagagaccaaagaggaagaggaagaggtggaaaagaagaagcagaag
aaggagaagcgggagactggaaaagccatggtgccccatagctctatgttcatcttcagc
accactaacccgatccgcaaggcttgccactacattgtgaatctacgctactttgagatg
tgcattctcttggtgattgcggccagcagcattgccctggcagctgaggaccctgtacta
actaactcagagcgtaacaaagtcctgagatatttcgactatgttttcacaggagtgttt
acctttgagatggtgataaagatgatagaccaaggcttgatcctgcaggatggatcgtac
ttccgagacctctggaatatcctggactttgtggtagtggttggtgcattggtagcattt
gctctggcgaacgctttgggaaccaacaaggggcgggatatcaagacgatcaagtctctg
agggtacttcgagttctgcgaccactgaaaaccatcaagcgcttgcccaaactgaaggct
gtgtttgactgcgtggtgacctccttgaagaatgtcttcaacatactcattgtctacaag
ctctttatgttcatctttgccgtcattgctgttcagttattcaagggaaagttcttttat
tgcaccgacagttccaaggacacagagaaggaatgcataggcaactatgtagaccacgag
aaaaacaagatggaggtgaagggccgggagtggaagcgtcatgaattccactatgacaac
atcatctgggccctgctgaccctcttcaccgtctccacgggggaaggatggcctcaggtt
ctgcagcactcggtagatgtgacagaggaggacagaggcccaagccgcagcaaccgcatg
gagatgtccatcttctatgtggtctactttgtggtcttccctttcttctttgtcaatatc
ttcgtggccctcattatcatcaccttccaggagcaaggggacaagatgatggaggagtgt
agcctagaaaagaatgagcgggcatgcatcgacttcgccattagtgccaaacctctcacc
cgctacatgccacaaaacaggcacaccttccagtaccgcgtgtggcacttcgtagtctcg
ccatcctttgagtataccatcatggccatgattgccttgaacaccgttgtgctgatgatg
aagtactattctgctccttggacctatgagctcgccctaaagtacctgaacatcgccttc
actatggtgttttccctagaatgtgtcctaaaggtcatcgctttcggcttcttgaactat
ttccgagatacctggaacatctttgacttcattaccgtgatcggcagtatcacagaaatt
atcctgacagacagcaagctggtgaacaccagtggcttcaatatgagctttctgaagctc
ttccgagctgcacggctcataaagcttctgcgacagggctacaccatccgcatcttactg
tggaccttcgtgcagtcctttaaggctctcccctatgtctgccttctgattgccatgctt
ttcttcatctacgctatcattgggatgcaggtgtttggaaacataaagttagatgaggag
agtcatatcaaccggcacaacaactttcggagtttcttcgggtctctcatgctgcttttc
aggagcgccacaggggaggcttggcaggagattatgttgtcatgtctgggcgagaagggc
tgtgagcctgacaccactgcaccctcagggcagaacgagagtgagcgctgtggcactgac
ctggcctacgtttattttgtctccttcatcttcttctgctccttcctgatgctcaacctg
tttgtggctgttatcatggacaactttgagtacctgactcgagattcgtccatcctgggg
cctcaccacttggatgaatttgtccgtgtctgggcagagtatgacagagcagcatgtggc
cgcatccattacactgagatgtatgaaatgctgactctcatgtcaccaccgctaggcctc
ggcaagagatgtccctccaaagtggcctataagaggttggtcctgatgaatatgccagtg
gctgaggacatgacagtccatttcacctccacacttatggctctgatccggacagctctg
gacattaaaatcgccaaaggtggtgcagacagacagcagctagactcagagctacaaaaa
gagaccctggccatttggcctcacctgtcccaaaagatgttggatctgctagtgcccatg
cccaaagcctctgacctgactgtgggcaagatctatgcagcaatgatgattatggactac
tataaacagagtaaggtaaagaaacagagacagcagctggaagaacagaaaaatgcaccc
atgttccagcgcatggagccctcctcactgcctcaggagatcatttctaatgccaaagcc
ctgccttatctccagcaggaccctgtttctggcctgagtggtcggagtggatacccttca
atgagtccactctcccctcaagaaatattccagttggcttgtatggacccagcggatgat
ggacaattccaggaacagcaatcgctggagccagaggttagtgaattaaaaagtgtgcag
tcctctaaccatggcatctaccttcctccggacacccaggagcatgcgggatctgggagg
gcatcctctatgccacgtctgactatggatccccaggtggtaacagaccctagctctatg
cgacgttcattttctacaattcgggataagcgttcaaattcctcctggttggaggagttc
tccatggaacgtagcagtgaaaacacctacaagtcacgacgcagaagttaccattcctcc
ctgaggctgtcagcccaccgcctgaattctgactctggtcacaagtctgacactcaccgc
tcaggaggcagggagagaggccgatccaaagaacgaaagcatctcctctctccggatgtc
tcccgctgcaattctgaggagcgaggaacccaggctgactgggagtccccagaacgtcgc
cagtccaggtcacccagtgagggaaggtcacaaacccccaacagacagggtacaggttca
ctgagtgagagctccattccctctatctccgacaccagcaccccaagacgaagtcgtcgc
cagctcccacctgtgccaccaaagcctcggcccctcctctcctacagctccctgatgaga
cacactggcggcatctctccacctcctgatggaagtgagggtggatccccactggcctct
caagctctggaaagcaacagcgcttgcctaaccgagtcttccaactccttgcacccccag
cagggccagcacccttccccacagcactacatctctgagccctatctggccctccatgaa
gactcccacgcctcagactgtggcgaggaggagacactcacctttgaggcagccgtagct
actagcttgggccggtccaataccattggctctgccccacccctacggcacagctggcag
atgcctaatgggcactatcggcggcggaggcgtggggggcctgggcctggcatgatgtgt
ggagctgtcagtgacctcctgagtgacacggaagaagacgataagtgctag

DBGET integrated database retrieval system