Rattus norvegicus (rat): 24493 Help Entry 24493             CDS       T01003                                  Symbol Il1a Name (RefSeq) interleukin-1 alpha   KO K04383   interleukin 1 alpha Organism rno  Rattus norvegicus (rat) Pathway rno04010   MAPK signaling pathway rno04060   Cytokine-cytokine receptor interaction rno04217   Necroptosis rno04218   Cellular senescence rno04380   Osteoclast differentiation rno04640   Hematopoietic cell lineage rno04932   Non-alcoholic fatty liver disease rno04933   AGE-RAGE signaling pathway in diabetic complications rno04940   Type I diabetes mellitus rno05010   Alzheimer disease rno05020   Prion disease rno05022   Pathways of neurodegeneration - multiple diseases rno05133   Pertussis rno05140   Leishmaniasis rno05152   Tuberculosis rno05162   Measles rno05164   Influenza A rno05321   Inflammatory bowel disease rno05323   Rheumatoid arthritis rno05332   Graft-versus-host disease rno05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     24493 (Il1a)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     24493 (Il1a)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     24493 (Il1a)    04218 Cellular senescence     24493 (Il1a)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     24493 (Il1a)   09158 Development and regeneration    04380 Osteoclast differentiation     24493 (Il1a)  09160 Human Diseases   09172 Infectious disease: viral    05164 Influenza A     24493 (Il1a)    05162 Measles     24493 (Il1a)   09171 Infectious disease: bacterial    05133 Pertussis     24493 (Il1a)    05152 Tuberculosis     24493 (Il1a)   09174 Infectious disease: parasitic    05140 Leishmaniasis     24493 (Il1a)   09163 Immune disease    05323 Rheumatoid arthritis     24493 (Il1a)    05321 Inflammatory bowel disease     24493 (Il1a)    05332 Graft-versus-host disease     24493 (Il1a)   09164 Neurodegenerative disease    05010 Alzheimer disease     24493 (Il1a)    05020 Prion disease     24493 (Il1a)    05022 Pathways of neurodegeneration - multiple diseases     24493 (Il1a)   09166 Cardiovascular disease    05418 Fluid shear stress and atherosclerosis     24493 (Il1a)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     24493 (Il1a)    04932 Non-alcoholic fatty liver disease     24493 (Il1a)    04933 AGE-RAGE signaling pathway in diabetic complications     24493 (Il1a)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:rno04052]     24493 (Il1a) Cytokines and growth factors [BR:rno04052]  Cytokines   Interleukins    24493 (Il1a) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL1_propep IL1 DUF5645 Motif Other DBs NCBI-GeneID:  24493 NCBI-ProteinID:  NP_058715 RGD:  2890 Ensembl:  ENSRNOG00000004575 UniProt:  P16598 LinkDB All DBs Position 3:complement(116526601..116537055) Genome browser AA seq 270 aa AA seqDB search MAKVPDLFEDLKNCYSENEEYSSAIDHLSLNQKSFYDASYGSLHENCTDKFVSLRTSETS KMSTFTFKESRVVVSATSNKGKILKKRRLSFNQPFTEDDLEAIAHDLEETIQPRSAPHSF QNNLRYKLIRIVKQEFIMNDSLNQNIYVDMDRIHLKAASLNDLQLEVKFDMYAYSSGGDD SKYPVTLKVSNTQLFVSAQGEDKPVLLKEIPETPKLITGSETDLIFFWEKINSKNYFTSA AFPELLIATKEQSQVHLARGLPSMIDFQIS NT seq 813 nt NT seq  +upstreamnt  +downstreamnt atggccaaagttcctgacttgtttgaagacctaaagaactgctatagtgaaaatgaagaa tacagttctgccattgaccatctgtctctgaatcagaaatccttctatgatgcaagctat ggctcacttcatgagaactgcacagataaatttgtatctctgagaacctctgaaacatca aagatgtccaccttcaccttcaaggagagccgggtggtggtgtcagcaacatcaaacaaa gggaagattctgaagaagagacggctaagtttcaatcagccctttactgaagatgacctg gaggccatagcccatgatttagaagagaccatccaacccagatcagcacctcacagcttc cagaataatttgagatacaaattgataaggatcgtcaagcaggagttcatcatgaatgat tccctcaaccaaaatatatatgtggatatggacagaatacatctcaaagctgcttcgtta aatgacctgcagcttgaagtaaaatttgacatgtatgcctactcatcgggaggagacgac tctaaatatcctgtgactctcaaagtctcaaatactcagctctttgtgagtgctcaggga gaagacaagcctgtgttgctgaaggagattccggaaacaccaaaactcatcacaggtagt gagaccgacctcattttcttctgggaaaaaatcaactctaagaactacttcacatccgca gctttcccagagctgttaattgccacaaaagaacaaagtcaggtgcacctggcacgggga ctgccctccatgatagatttccagatatcataa

Rattus norvegicus (rat): 24494 Help Entry 24494             CDS       T01003                                  Symbol Il1b Name (RefSeq) interleukin-1 beta   KO K04519   interleukin 1 beta Organism rno  Rattus norvegicus (rat) Pathway rno01523   Antifolate resistance rno04010   MAPK signaling pathway rno04060   Cytokine-cytokine receptor interaction rno04064   NF-kappa B signaling pathway rno04217   Necroptosis rno04380   Osteoclast differentiation rno04620   Toll-like receptor signaling pathway rno04621   NOD-like receptor signaling pathway rno04623   Cytosolic DNA-sensing pathway rno04625   C-type lectin receptor signaling pathway rno04640   Hematopoietic cell lineage rno04657   IL-17 signaling pathway rno04659   Th17 cell differentiation rno04668   TNF signaling pathway rno04750   Inflammatory mediator regulation of TRP channels rno04932   Non-alcoholic fatty liver disease rno04933   AGE-RAGE signaling pathway in diabetic complications rno04936   Alcoholic liver disease rno04940   Type I diabetes mellitus rno05010   Alzheimer disease rno05020   Prion disease rno05022   Pathways of neurodegeneration - multiple diseases rno05132   Salmonella infection rno05133   Pertussis rno05134   Legionellosis rno05135   Yersinia infection rno05140   Leishmaniasis rno05142   Chagas disease rno05143   African trypanosomiasis rno05144   Malaria rno05146   Amoebiasis rno05152   Tuberculosis rno05162   Measles rno05163   Human cytomegalovirus infection rno05164   Influenza A rno05168   Herpes simplex virus 1 infection rno05171   Coronavirus disease - COVID-19 rno05321   Inflammatory bowel disease rno05323   Rheumatoid arthritis rno05332   Graft-versus-host disease rno05417   Lipid and atherosclerosis rno05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     24494 (Il1b)    04064 NF-kappa B signaling pathway     24494 (Il1b)    04668 TNF signaling pathway     24494 (Il1b)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     24494 (Il1b)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     24494 (Il1b)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     24494 (Il1b)    04620 Toll-like receptor signaling pathway     24494 (Il1b)    04621 NOD-like receptor signaling pathway     24494 (Il1b)    04623 Cytosolic DNA-sensing pathway     24494 (Il1b)    04625 C-type lectin receptor signaling pathway     24494 (Il1b)    04659 Th17 cell differentiation     24494 (Il1b)    04657 IL-17 signaling pathway     24494 (Il1b)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     24494 (Il1b)   09158 Development and regeneration    04380 Osteoclast differentiation     24494 (Il1b)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     24494 (Il1b)    05164 Influenza A     24494 (Il1b)    05162 Measles     24494 (Il1b)    05168 Herpes simplex virus 1 infection     24494 (Il1b)    05163 Human cytomegalovirus infection     24494 (Il1b)   09171 Infectious disease: bacterial    05132 Salmonella infection     24494 (Il1b)    05135 Yersinia infection     24494 (Il1b)    05133 Pertussis     24494 (Il1b)    05134 Legionellosis     24494 (Il1b)    05152 Tuberculosis     24494 (Il1b)   09174 Infectious disease: parasitic    05146 Amoebiasis     24494 (Il1b)    05144 Malaria     24494 (Il1b)    05140 Leishmaniasis     24494 (Il1b)    05142 Chagas disease     24494 (Il1b)    05143 African trypanosomiasis     24494 (Il1b)   09163 Immune disease    05323 Rheumatoid arthritis     24494 (Il1b)    05321 Inflammatory bowel disease     24494 (Il1b)    05332 Graft-versus-host disease     24494 (Il1b)   09164 Neurodegenerative disease    05010 Alzheimer disease     24494 (Il1b)    05020 Prion disease     24494 (Il1b)    05022 Pathways of neurodegeneration - multiple diseases     24494 (Il1b)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     24494 (Il1b)    05418 Fluid shear stress and atherosclerosis     24494 (Il1b)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     24494 (Il1b)    04936 Alcoholic liver disease     24494 (Il1b)    04932 Non-alcoholic fatty liver disease     24494 (Il1b)    04933 AGE-RAGE signaling pathway in diabetic complications     24494 (Il1b)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     24494 (Il1b)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and growth factors [BR:rno04052]     24494 (Il1b)    00536 Glycosaminoglycan binding proteins [BR:rno00536]     24494 (Il1b) Cytokines and growth factors [BR:rno04052]  Cytokines   Interleukins    24494 (Il1b) Glycosaminoglycan binding proteins [BR:rno00536]  Heparan sulfate / Heparin   Cytokines    24494 (Il1b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL1 IL1_propep ZinT Motif Other DBs NCBI-GeneID:  24494 NCBI-ProteinID:  NP_113700 RGD:  2891 Ensembl:  ENSRNOG00000004649 UniProt:  F7F755 Q5BKB0 LinkDB All DBs Position 3:complement(116577005..116583386) Genome browser AA seq 268 aa AA seqDB search MATVPELNCEIAAFDSEENDLFFEADRPQKIKDCFQALDLGCPDESIQLQISQQHLDKSF RKAVSLIVAVEKLWQLPMSCPWSFQDEDPSTFFSFIFEEEPVLCDSWDDDDLLVCDVPIR QLHCRLRDEQQKCLVLSDPCELKALHLNGQNISQQVVFSMSFVQGETSNDKIPVALGLKG KNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKTKVEFESAQFPNWYIST SQAEHRPVFLGNSNGRDIVDFTMEPVSS NT seq 807 nt NT seq  +upstreamnt  +downstreamnt atggcaactgtccctgaactcaactgtgaaatagcagctttcgacagtgaggagaatgac ctgttctttgaggctgacagaccccaaaagattaaggattgcttccaagcccttgacttg ggctgtccagatgagagcatccagcttcaaatctcacagcagcatctcgacaagagcttc aggaaggcagtgtcactcattgtggctgtggagaagctgtggcagctacctatgtcttgc ccgtggagcttccaggatgaggacccaagcaccttcttttccttcatctttgaagaagag cccgtcctctgtgactcgtgggatgatgacgacctgctagtgtgtgatgttcccattaga cagctgcactgcaggcttcgagatgaacaacaaaaatgcctcgtgctgtctgacccatgt gagctgaaagctctccacctcaatggacagaacataagccaacaagtggtattctccatg agctttgtacaaggagagacaagcaacgacaaaatccctgtggccttgggcctcaagggg aagaatctatacctgtcctgtgtgatgaaagacggcacacccaccctgcagctggagagt gtggatcccaaacaatacccaaagaagaagatggaaaagcggtttgtcttcaacaagata gaagtcaagaccaaagtggagtttgagtctgcacagttccccaactggtacatcagcacc tctcaagcagagcacagacctgtcttcctaggaaacagcaatggtcgggacatagttgac ttcaccatggaacccgtgtcttcctaa

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