Rattus norvegicus (rat): 24680 Help Entry 24680             CDS       T01003                                  Symbol Prkca Name (RefSeq) protein kinase C alpha type   KO K02677   classical protein kinase C alpha type [EC:2.7.11.13] Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno04010   MAPK signaling pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04066   HIF-1 signaling pathway rno04070   Phosphatidylinositol signaling system rno04071   Sphingolipid signaling pathway rno04072   Phospholipase D signaling pathway rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04261   Adrenergic signaling in cardiomyocytes rno04270   Vascular smooth muscle contraction rno04310   Wnt signaling pathway rno04360   Axon guidance rno04370   VEGF signaling pathway rno04510   Focal adhesion rno04540   Gap junction rno04613   Neutrophil extracellular trap formation rno04650   Natural killer cell mediated cytotoxicity rno04664   Fc epsilon RI signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno04670   Leukocyte transendothelial migration rno04713   Circadian entrainment rno04720   Long-term potentiation rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04726   Serotonergic synapse rno04727   GABAergic synapse rno04728   Dopaminergic synapse rno04730   Long-term depression rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04919   Thyroid hormone signaling pathway rno04921   Oxytocin signaling pathway rno04925   Aldosterone synthesis and secretion rno04926   Relaxin signaling pathway rno04928   Parathyroid hormone synthesis, secretion and action rno04929   GnRH secretion rno04933   AGE-RAGE signaling pathway in diabetic complications rno04935   Growth hormone synthesis, secretion and action rno04960   Aldosterone-regulated sodium reabsorption rno04961   Endocrine and other factor-regulated calcium reabsorption rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno05017   Spinocerebellar ataxia rno05022   Pathways of neurodegeneration - multiple diseases rno05031   Amphetamine addiction rno05032   Morphine addiction rno05143   African trypanosomiasis rno05146   Amoebiasis rno05161   Hepatitis B rno05163   Human cytomegalovirus infection rno05164   Influenza A rno05170   Human immunodeficiency virus 1 infection rno05171   Coronavirus disease - COVID-19 rno05200   Pathways in cancer rno05205   Proteoglycans in cancer rno05206   MicroRNAs in cancer rno05207   Chemical carcinogenesis - receptor activation rno05214   Glioma rno05223   Non-small cell lung cancer rno05225   Hepatocellular carcinoma rno05231   Choline metabolism in cancer rno05415   Diabetic cardiomyopathy rno05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     24680 (Prkca)    04012 ErbB signaling pathway     24680 (Prkca)    04014 Ras signaling pathway     24680 (Prkca)    04015 Rap1 signaling pathway     24680 (Prkca)    04310 Wnt signaling pathway     24680 (Prkca)    04370 VEGF signaling pathway     24680 (Prkca)    04066 HIF-1 signaling pathway     24680 (Prkca)    04020 Calcium signaling pathway     24680 (Prkca)    04070 Phosphatidylinositol signaling system     24680 (Prkca)    04072 Phospholipase D signaling pathway     24680 (Prkca)    04071 Sphingolipid signaling pathway     24680 (Prkca)    04151 PI3K-Akt signaling pathway     24680 (Prkca)    04150 mTOR signaling pathway     24680 (Prkca)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     24680 (Prkca)    04540 Gap junction     24680 (Prkca)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     24680 (Prkca)    04650 Natural killer cell mediated cytotoxicity     24680 (Prkca)    04664 Fc epsilon RI signaling pathway     24680 (Prkca)    04666 Fc gamma R-mediated phagocytosis     24680 (Prkca)    04670 Leukocyte transendothelial migration     24680 (Prkca)   09152 Endocrine system    04911 Insulin secretion     24680 (Prkca)    04929 GnRH secretion     24680 (Prkca)    04912 GnRH signaling pathway     24680 (Prkca)    04921 Oxytocin signaling pathway     24680 (Prkca)    04926 Relaxin signaling pathway     24680 (Prkca)    04935 Growth hormone synthesis, secretion and action     24680 (Prkca)    04918 Thyroid hormone synthesis     24680 (Prkca)    04919 Thyroid hormone signaling pathway     24680 (Prkca)    04928 Parathyroid hormone synthesis, secretion and action     24680 (Prkca)    04916 Melanogenesis     24680 (Prkca)    04925 Aldosterone synthesis and secretion     24680 (Prkca)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     24680 (Prkca)    04270 Vascular smooth muscle contraction     24680 (Prkca)   09154 Digestive system    04970 Salivary secretion     24680 (Prkca)    04971 Gastric acid secretion     24680 (Prkca)    04972 Pancreatic secretion     24680 (Prkca)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     24680 (Prkca)    04961 Endocrine and other factor-regulated calcium reabsorption     24680 (Prkca)   09156 Nervous system    04724 Glutamatergic synapse     24680 (Prkca)    04727 GABAergic synapse     24680 (Prkca)    04725 Cholinergic synapse     24680 (Prkca)    04728 Dopaminergic synapse     24680 (Prkca)    04726 Serotonergic synapse     24680 (Prkca)    04720 Long-term potentiation     24680 (Prkca)    04730 Long-term depression     24680 (Prkca)    04723 Retrograde endocannabinoid signaling     24680 (Prkca)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     24680 (Prkca)   09158 Development and regeneration    04360 Axon guidance     24680 (Prkca)   09159 Environmental adaptation    04713 Circadian entrainment     24680 (Prkca)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     24680 (Prkca)    05206 MicroRNAs in cancer     24680 (Prkca)    05205 Proteoglycans in cancer     24680 (Prkca)    05207 Chemical carcinogenesis - receptor activation     24680 (Prkca)    05231 Choline metabolism in cancer     24680 (Prkca)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     24680 (Prkca)    05214 Glioma     24680 (Prkca)    05223 Non-small cell lung cancer     24680 (Prkca)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     24680 (Prkca)    05161 Hepatitis B     24680 (Prkca)    05171 Coronavirus disease - COVID-19     24680 (Prkca)    05164 Influenza A     24680 (Prkca)    05163 Human cytomegalovirus infection     24680 (Prkca)   09174 Infectious disease: parasitic    05146 Amoebiasis     24680 (Prkca)    05143 African trypanosomiasis     24680 (Prkca)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     24680 (Prkca)    05022 Pathways of neurodegeneration - multiple diseases     24680 (Prkca)   09165 Substance dependence    05031 Amphetamine addiction     24680 (Prkca)    05032 Morphine addiction     24680 (Prkca)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     24680 (Prkca)    05415 Diabetic cardiomyopathy     24680 (Prkca)   09167 Endocrine and metabolic disease    04933 AGE-RAGE signaling pathway in diabetic complications     24680 (Prkca)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     24680 (Prkca)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     24680 (Prkca)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     24680 (Prkca) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      24680 (Prkca) Protein kinases [BR:rno01001]  Serine/threonine kinases: AGC group   PKC family [OT]    24680 (Prkca) Membrane trafficking [BR:rno04131]  Endocytosis   Lipid raft mediated endocytosis    Caveolin-mediated endocytosis     24680 (Prkca) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 C1_2 DUF4656 Motif Other DBs NCBI-GeneID:  24680 NCBI-ProteinID:  NP_001099183 RGD:  3395 Ensembl:  ENSRNOG00000003491 UniProt:  F1M2P8 A6HK91 LinkDB All DBs Position 10:complement(92889390..93288013) Genome browser AA seq 636 aa AA seqDB search MADVYPANDSTASQDVANRFARKGALRQKNVHEVKDHKFIARFFKQPTFCSHCTDFIWGF GKQGFQCQVCCFVVHKRCHEFVTFSCPGADKGPDTDDPRSKHKFKIHTYGSPTFCDHCGS LLYGLIHQGMKCDTCDMNVHKQCVINVPSLCGMDHTEKRGRIYLKAEVTDEKLHVTVRDA KNLIPMDPNGLSDPYVKLKLIPDPKNESKQKTKTIRSTLNPQWNESFTFKLKPSDKDRRL SVEIWDWDRTTRNDFMGSLSFGVSELMKMPASGWYKLLNQEEGEYYNVPIPEGDEEGNVE LRQKFEKAKLGPAGNKVISPSEDRKQPSNNLDRVKLTDFNFLMVLGKGSFGKVMLADRKG TEELYAIKILKKDVVIQDDDVECTMVEKRVLALLDKPPFLTQLHSCFQTVDRLYFVMEYV NGGDLMYHIQQVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLDSEGHIKIA DFGMCKEHMMDGVTTRTFCGTPDYIAPEIIAYQPYGKSVDWWAYGVLLYEMLAGQLMTKH PAKRLGCGPEGERDVREHAFFRRIDWEKLENREIQPPFKPKVCGKGAENFDKFFTRGQPV LTPPDQLVIANIDQSDFEGFSYVNPQFVHPILQSAV NT seq 1911 nt NT seq  +upstreamnt  +downstreamnt atggctgacgtttacccggccaacgactccacggcgtctcaggacgtggccaaccgcttc gcccgcaaaggggcgctgaggcagaagaacgtgcatgaggtgaaagaccacaaattcatc gcccgcttcttcaagcaacccaccttctgcagccactgcaccgacttcatctgggggttt ggaaaacaaggcttccagtgccaagtttgctgttttgtggttcacaagaggtgccatgag tttgttactttctcttgtccgggtgcggataagggacctgacactgatgaccccagaagc aagcacaagttcaaaatccacacctatggaagccctaccttctgtgatcactgtgggtcc ctgctctacggacttatccaccaagggatgaaatgcgacacctgcgacatgaatgttcac aagcagtgcgtgatcaatgtccccagcctctgcggaatggatcacacagagaagaggggg cggatttacctgaaggcagaggtcacagatgaaaagctgcacgtcaccgtacgagatgca aaaaatctaatccctatggatccaaatgggctttcggatccttacgtgaagctgaaactt attcctgaccccaagaatgagagcaaacagaaaaccaaaaccatccgatccacactgaac cctcagtggaatgagtccttcacgttcaaattaaaaccttcagacaaagaccggcgactg tccgtagaaatctgggactgggatcggacgacacggaatgacttcatgggctccctttcc ttcggcgtctcagagctgatgaagatgccagccagtggatggtacaagttgctcaaccaa gaggagggtgaatactacaatgtgcccattccagaaggagatgaagaaggcaacgtggaa ctcaggcagaagttcgagaaagccaagctgggccccgctggaaacaaagtcatcagccct tcagaagacaggaagcagccatctaacaacctggacagggtgaaactcacagacttcaac ttcctcatggtgctggggaaggggagttttggaaaggtgatgcttgctgacaggaaggga acagaggaactgtacgccatcaaaatcctgaagaaggacgtggtgatccaggatgacgac gtggagtgcaccatggtggagaagcgggttctggccctgctcgacaagcccccgttcctg acacagctgcactcctgcttccagacagtggaccggctgtacttcgtcatggaatacgtc aacggtggggacctcatgtaccacattcagcaagtcggaaaatttaaggagccacaagca gtattctatgcagccgagatctccatcggactgttctttcttcacaaaagaggaatcatt tacagggatctgaagctggacaacgtcatgctggactcagaagggcatatcaaaatcgcc gacttcgggatgtgcaaggaacacatgatggacggggtcacgaccaggaccttctgtggg actccggattacattgccccagagataatcgcttaccagccatatggaaagtctgtggac tggtgggcgtacggcgtgctcctgtatgagatgctagctgggcagcttatgaccaaacac cctgccaagcggctgggctgcgggcccgagggggaaagggatgtcagagagcatgccttc tttaggaggatcgactgggagaagttggagaacagggagatccaaccgccattcaagccc aaagtgtgcggcaaaggagcagaaaactttgacaagttcttcacacgagggcagcctgtc ttaacaccaccagatcagctggtcatcgctaacatagaccagtctgattttgaagggttc tcgtatgtcaacccccagtttgtgcacccaatcttgcaaagtgcagtatga

Rattus norvegicus (rat): 24681 Help Entry 24681             CDS       T01003                                  Symbol Prkcg Name (RefSeq) protein kinase C gamma type   KO K19663   classical protein kinase C gamma type [EC:2.7.11.13] Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno04010   MAPK signaling pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04066   HIF-1 signaling pathway rno04070   Phosphatidylinositol signaling system rno04071   Sphingolipid signaling pathway rno04150   mTOR signaling pathway rno04270   Vascular smooth muscle contraction rno04310   Wnt signaling pathway rno04370   VEGF signaling pathway rno04510   Focal adhesion rno04540   Gap junction rno04613   Neutrophil extracellular trap formation rno04650   Natural killer cell mediated cytotoxicity rno04666   Fc gamma R-mediated phagocytosis rno04670   Leukocyte transendothelial migration rno04713   Circadian entrainment rno04720   Long-term potentiation rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04726   Serotonergic synapse rno04727   GABAergic synapse rno04728   Dopaminergic synapse rno04730   Long-term depression rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04919   Thyroid hormone signaling pathway rno04921   Oxytocin signaling pathway rno04925   Aldosterone synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04929   GnRH secretion rno04935   Growth hormone synthesis, secretion and action rno04960   Aldosterone-regulated sodium reabsorption rno04961   Endocrine and other factor-regulated calcium reabsorption rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno05017   Spinocerebellar ataxia rno05022   Pathways of neurodegeneration - multiple diseases rno05031   Amphetamine addiction rno05032   Morphine addiction rno05143   African trypanosomiasis rno05146   Amoebiasis rno05161   Hepatitis B rno05163   Human cytomegalovirus infection rno05170   Human immunodeficiency virus 1 infection rno05171   Coronavirus disease - COVID-19 rno05200   Pathways in cancer rno05205   Proteoglycans in cancer rno05206   MicroRNAs in cancer rno05207   Chemical carcinogenesis - receptor activation rno05214   Glioma rno05223   Non-small cell lung cancer rno05225   Hepatocellular carcinoma rno05231   Choline metabolism in cancer rno05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     24681 (Prkcg)    04012 ErbB signaling pathway     24681 (Prkcg)    04014 Ras signaling pathway     24681 (Prkcg)    04015 Rap1 signaling pathway     24681 (Prkcg)    04310 Wnt signaling pathway     24681 (Prkcg)    04370 VEGF signaling pathway     24681 (Prkcg)    04066 HIF-1 signaling pathway     24681 (Prkcg)    04020 Calcium signaling pathway     24681 (Prkcg)    04070 Phosphatidylinositol signaling system     24681 (Prkcg)    04071 Sphingolipid signaling pathway     24681 (Prkcg)    04150 mTOR signaling pathway     24681 (Prkcg)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     24681 (Prkcg)    04540 Gap junction     24681 (Prkcg)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     24681 (Prkcg)    04650 Natural killer cell mediated cytotoxicity     24681 (Prkcg)    04666 Fc gamma R-mediated phagocytosis     24681 (Prkcg)    04670 Leukocyte transendothelial migration     24681 (Prkcg)   09152 Endocrine system    04911 Insulin secretion     24681 (Prkcg)    04929 GnRH secretion     24681 (Prkcg)    04921 Oxytocin signaling pathway     24681 (Prkcg)    04935 Growth hormone synthesis, secretion and action     24681 (Prkcg)    04918 Thyroid hormone synthesis     24681 (Prkcg)    04919 Thyroid hormone signaling pathway     24681 (Prkcg)    04928 Parathyroid hormone synthesis, secretion and action     24681 (Prkcg)    04916 Melanogenesis     24681 (Prkcg)    04925 Aldosterone synthesis and secretion     24681 (Prkcg)   09153 Circulatory system    04270 Vascular smooth muscle contraction     24681 (Prkcg)   09154 Digestive system    04970 Salivary secretion     24681 (Prkcg)    04971 Gastric acid secretion     24681 (Prkcg)    04972 Pancreatic secretion     24681 (Prkcg)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     24681 (Prkcg)    04961 Endocrine and other factor-regulated calcium reabsorption     24681 (Prkcg)   09156 Nervous system    04724 Glutamatergic synapse     24681 (Prkcg)    04727 GABAergic synapse     24681 (Prkcg)    04725 Cholinergic synapse     24681 (Prkcg)    04728 Dopaminergic synapse     24681 (Prkcg)    04726 Serotonergic synapse     24681 (Prkcg)    04720 Long-term potentiation     24681 (Prkcg)    04730 Long-term depression     24681 (Prkcg)    04723 Retrograde endocannabinoid signaling     24681 (Prkcg)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     24681 (Prkcg)   09159 Environmental adaptation    04713 Circadian entrainment     24681 (Prkcg)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     24681 (Prkcg)    05206 MicroRNAs in cancer     24681 (Prkcg)    05205 Proteoglycans in cancer     24681 (Prkcg)    05207 Chemical carcinogenesis - receptor activation     24681 (Prkcg)    05231 Choline metabolism in cancer     24681 (Prkcg)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     24681 (Prkcg)    05214 Glioma     24681 (Prkcg)    05223 Non-small cell lung cancer     24681 (Prkcg)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     24681 (Prkcg)    05161 Hepatitis B     24681 (Prkcg)    05171 Coronavirus disease - COVID-19     24681 (Prkcg)    05163 Human cytomegalovirus infection     24681 (Prkcg)   09174 Infectious disease: parasitic    05146 Amoebiasis     24681 (Prkcg)    05143 African trypanosomiasis     24681 (Prkcg)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     24681 (Prkcg)    05022 Pathways of neurodegeneration - multiple diseases     24681 (Prkcg)   09165 Substance dependence    05031 Amphetamine addiction     24681 (Prkcg)    05032 Morphine addiction     24681 (Prkcg)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     24681 (Prkcg)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     24681 (Prkcg)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     24681 (Prkcg) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      24681 (Prkcg) Protein kinases [BR:rno01001]  Serine/threonine kinases: AGC group   PKC family [OT]    24681 (Prkcg) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase C1_1 PK_Tyr_Ser-Thr C2 Pkinase_C ABC1 Kinase-like Motif Other DBs NCBI-GeneID:  24681 NCBI-ProteinID:  NP_036760 RGD:  3397 Ensembl:  ENSRNOG00000054371 UniProt:  P63319 A6KS41 Structure PDB LinkDB All DBs Position 1:complement(65832851..65860676) Genome browser AA seq 697 aa AA seqDB search MAGLGPGGGDSEGGPRPLFCRKGALRQKVVHEVKSHKFTARFFKQPTFCSHCTDFIWGIG KQGLQCQVCSFVVHRRCHEFVTFECPGAGKGPQTDDPRNKHKFRLHSYSSPTFCDHCGSL LYGLVHQGMKCSCCEMNVHRRCVRSVPSLCGVDHTERRGRLQLEIRAPTSDEIHITVGEA RNLIPMDPNGLSDPYVKLKLIPDPRNLTKQKTKTVKATLNPVWNETFVFNLKPGDVERRL SVEVWDWDRTSRNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADADNCSLLQ KFEACNYPLELYERVRMGPSSSPIPSPSPSPTDSKRCFFGASPGRLHISDFSFLMVLGKG SFGKVMLAERRGSDELYAIKILKKDVIVQDDDVDCTLVEKRVLALGGRGPGGRPHFLTQL HSTFQTPDRLYFVMEYVTGGDLMYHIQQLGKFKEPHAAFYAAEIAIGLFFLHNQGIIYRD LKLDNVMLDAEGHIKITDFGMCKENVFPGSTTRTFCGTPDYIAPEIIAYQPYGKSVDWWS FGVLLYEMLAGQPPFDGEDEEELFQAIMEQTVTYPKSLSREAVAICKGFLTKHPGKRLGS GPDGEPTIRAHGFFRWIDWERLERLEIAPPFRPRPCGRSGENFDKFFTRAAPALTPPDRL VLASIDQADFQGFTYVNPDFVHPDARSPTSPVPVPVM NT seq 2094 nt NT seq  +upstreamnt  +downstreamnt atggcgggtctgggtcctggcgggggcgactcagaagggggaccccgacccctgttttgc agaaagggggcgctgaggcagaaggtggtccacgaggtgaagagccacaagttcaccgct cgtttcttcaagcagccaaccttctgcagtcactgtaccgacttcatctggggcattgga aagcagggcctgcaatgtcaagtctgcagctttgtggttcaccgccgatgccacgaattt gtgaccttcgagtgtccaggagctggaaagggcccccagacggacgaccctcgcaacaag cacaagttccgtctgcacagctacagcagtcccaccttctgcgaccactgtggttccctc ctctacgggctggtgcaccagggcatgaaatgttcctgttgcgaaatgaatgtgcaccga cgctgtgtgcgcagcgtgccctccctttgcggcgtggaccatacagagcgccgtggacgt ctgcaactggaaatccgggctcccacatcagatgagatccatattactgtgggtgaggcc cggaacctcattcctatggaccccaatggcctgtctgatccctatgtgaaactgaagctc atcccggaccctcggaacctgacaaaacagaagacaaagaccgtgaaagccacactgaat cccgtgtggaacgagaccttcgtgttcaacctgaagccgggggatgtggagcgccggctc agtgtggaggtgtgggattgggataggacatcccgaaatgacttcatgggtgccatgtcc tttggtgtctcagagctactcaaggctcctgtggatggatggtacaagttactgaaccag gaggagggcgagtattacaatgtaccggtggccgatgctgacaactgcagcctcctccag aagtttgaggcctgtaattaccccttggaattgtatgagagagtgcggatgggcccctct tcctctcccattccttctccatcccccagtcccacggactccaagagatgcttcttcggt gccagcccaggacgcctgcatatctctgacttcagcttcctcatggttctagggaaaggc agttttgggaaggtgatgctggcagagcgcagaggatccgatgaactctatgccatcaag atactgaaaaaagacgtcattgtccaggatgatgatgtagactgcacccttgtggagaag cgtgtgctggcattgggaggccgaggtcctggaggccggccacactttctcacacaactt cattccacctttcagactccggaccgcctgtattttgtgatggagtacgtcactgggggc gatttaatgtaccacattcagcaactgggcaagtttaaggagccccacgcagcattctat gccgcggaaatcgccataggcctcttcttccttcacaaccagggcatcatctacagggac ctcaagttggataatgtgatgctggatgctgaaggacacatcaagatcacagacttcggc atgtgtaaagagaatgtcttccctgggtccacaacccgcaccttctgtgggaccccagac tacatagcacctgagatcattgcctatcagccctatgggaagtctgtcgactggtggtcc tttggagtcctgctgtatgagatgttggcaggacagccaccctttgatggggaagatgag gaggagctgtttcaagccatcatggaacaaactgtcacctatcccaagtcactttcccgg gaagctgtggccatctgcaaggggttcctgaccaagcacccaggaaagcgcctgggctca gggccagatggggaacccaccatccgggctcatggctttttccgttggatcgattgggag aggttggagagactggaaattgcgcctccttttagaccacgtccgtgtggccgcagcggc gaaaactttgacaagttcttcacgcgggcagcgccagccttgaccccgccagaccgcttg gtcctagccagcatcgaccaagctgatttccagggctttacttatgtgaacccggacttc gtgcacccagatgcccgcagccccacaagccctgtgcctgtgcccgtcatgtaa

Rattus norvegicus (rat): 25023 Help Entry 25023             CDS       T01003                                  Symbol Prkcb Name (RefSeq) protein kinase C beta type isoform 2   KO K19662   classical protein kinase C beta type [EC:2.7.11.13] Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno04010   MAPK signaling pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04015   Rap1 signaling pathway rno04020   Calcium signaling pathway rno04062   Chemokine signaling pathway rno04064   NF-kappa B signaling pathway rno04066   HIF-1 signaling pathway rno04070   Phosphatidylinositol signaling system rno04071   Sphingolipid signaling pathway rno04150   mTOR signaling pathway rno04270   Vascular smooth muscle contraction rno04310   Wnt signaling pathway rno04370   VEGF signaling pathway rno04510   Focal adhesion rno04540   Gap junction rno04613   Neutrophil extracellular trap formation rno04650   Natural killer cell mediated cytotoxicity rno04662   B cell receptor signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno04670   Leukocyte transendothelial migration rno04713   Circadian entrainment rno04720   Long-term potentiation rno04723   Retrograde endocannabinoid signaling rno04724   Glutamatergic synapse rno04725   Cholinergic synapse rno04726   Serotonergic synapse rno04727   GABAergic synapse rno04728   Dopaminergic synapse rno04730   Long-term depression rno04750   Inflammatory mediator regulation of TRP channels rno04911   Insulin secretion rno04912   GnRH signaling pathway rno04916   Melanogenesis rno04918   Thyroid hormone synthesis rno04919   Thyroid hormone signaling pathway rno04921   Oxytocin signaling pathway rno04925   Aldosterone synthesis and secretion rno04928   Parathyroid hormone synthesis, secretion and action rno04929   GnRH secretion rno04931   Insulin resistance rno04933   AGE-RAGE signaling pathway in diabetic complications rno04935   Growth hormone synthesis, secretion and action rno04960   Aldosterone-regulated sodium reabsorption rno04961   Endocrine and other factor-regulated calcium reabsorption rno04970   Salivary secretion rno04971   Gastric acid secretion rno04972   Pancreatic secretion rno04973   Carbohydrate digestion and absorption rno05017   Spinocerebellar ataxia rno05022   Pathways of neurodegeneration - multiple diseases rno05031   Amphetamine addiction rno05032   Morphine addiction rno05140   Leishmaniasis rno05143   African trypanosomiasis rno05146   Amoebiasis rno05161   Hepatitis B rno05163   Human cytomegalovirus infection rno05164   Influenza A rno05170   Human immunodeficiency virus 1 infection rno05171   Coronavirus disease - COVID-19 rno05200   Pathways in cancer rno05205   Proteoglycans in cancer rno05206   MicroRNAs in cancer rno05207   Chemical carcinogenesis - receptor activation rno05214   Glioma rno05223   Non-small cell lung cancer rno05225   Hepatocellular carcinoma rno05231   Choline metabolism in cancer rno05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     25023 (Prkcb)    04012 ErbB signaling pathway     25023 (Prkcb)    04014 Ras signaling pathway     25023 (Prkcb)    04015 Rap1 signaling pathway     25023 (Prkcb)    04310 Wnt signaling pathway     25023 (Prkcb)    04370 VEGF signaling pathway     25023 (Prkcb)    04064 NF-kappa B signaling pathway     25023 (Prkcb)    04066 HIF-1 signaling pathway     25023 (Prkcb)    04020 Calcium signaling pathway     25023 (Prkcb)    04070 Phosphatidylinositol signaling system     25023 (Prkcb)    04071 Sphingolipid signaling pathway     25023 (Prkcb)    04150 mTOR signaling pathway     25023 (Prkcb)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     25023 (Prkcb)    04540 Gap junction     25023 (Prkcb)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     25023 (Prkcb)    04650 Natural killer cell mediated cytotoxicity     25023 (Prkcb)    04662 B cell receptor signaling pathway     25023 (Prkcb)    04666 Fc gamma R-mediated phagocytosis     25023 (Prkcb)    04670 Leukocyte transendothelial migration     25023 (Prkcb)    04062 Chemokine signaling pathway     25023 (Prkcb)   09152 Endocrine system    04911 Insulin secretion     25023 (Prkcb)    04929 GnRH secretion     25023 (Prkcb)    04912 GnRH signaling pathway     25023 (Prkcb)    04921 Oxytocin signaling pathway     25023 (Prkcb)    04935 Growth hormone synthesis, secretion and action     25023 (Prkcb)    04918 Thyroid hormone synthesis     25023 (Prkcb)    04919 Thyroid hormone signaling pathway     25023 (Prkcb)    04928 Parathyroid hormone synthesis, secretion and action     25023 (Prkcb)    04916 Melanogenesis     25023 (Prkcb)    04925 Aldosterone synthesis and secretion     25023 (Prkcb)   09153 Circulatory system    04270 Vascular smooth muscle contraction     25023 (Prkcb)   09154 Digestive system    04970 Salivary secretion     25023 (Prkcb)    04971 Gastric acid secretion     25023 (Prkcb)    04972 Pancreatic secretion     25023 (Prkcb)    04973 Carbohydrate digestion and absorption     25023 (Prkcb)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     25023 (Prkcb)    04961 Endocrine and other factor-regulated calcium reabsorption     25023 (Prkcb)   09156 Nervous system    04724 Glutamatergic synapse     25023 (Prkcb)    04727 GABAergic synapse     25023 (Prkcb)    04725 Cholinergic synapse     25023 (Prkcb)    04728 Dopaminergic synapse     25023 (Prkcb)    04726 Serotonergic synapse     25023 (Prkcb)    04720 Long-term potentiation     25023 (Prkcb)    04730 Long-term depression     25023 (Prkcb)    04723 Retrograde endocannabinoid signaling     25023 (Prkcb)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     25023 (Prkcb)   09159 Environmental adaptation    04713 Circadian entrainment     25023 (Prkcb)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     25023 (Prkcb)    05206 MicroRNAs in cancer     25023 (Prkcb)    05205 Proteoglycans in cancer     25023 (Prkcb)    05207 Chemical carcinogenesis - receptor activation     25023 (Prkcb)    05231 Choline metabolism in cancer     25023 (Prkcb)   09162 Cancer: specific types    05225 Hepatocellular carcinoma     25023 (Prkcb)    05214 Glioma     25023 (Prkcb)    05223 Non-small cell lung cancer     25023 (Prkcb)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     25023 (Prkcb)    05161 Hepatitis B     25023 (Prkcb)    05171 Coronavirus disease - COVID-19     25023 (Prkcb)    05164 Influenza A     25023 (Prkcb)    05163 Human cytomegalovirus infection     25023 (Prkcb)   09174 Infectious disease: parasitic    05146 Amoebiasis     25023 (Prkcb)    05140 Leishmaniasis     25023 (Prkcb)    05143 African trypanosomiasis     25023 (Prkcb)   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     25023 (Prkcb)    05022 Pathways of neurodegeneration - multiple diseases     25023 (Prkcb)   09165 Substance dependence    05031 Amphetamine addiction     25023 (Prkcb)    05032 Morphine addiction     25023 (Prkcb)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     25023 (Prkcb)   09167 Endocrine and metabolic disease    04931 Insulin resistance     25023 (Prkcb)    04933 AGE-RAGE signaling pathway in diabetic complications     25023 (Prkcb)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     25023 (Prkcb)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     25023 (Prkcb) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.13  protein kinase C      25023 (Prkcb) Protein kinases [BR:rno01001]  Serine/threonine kinases: AGC group   PKC family [OT]    25023 (Prkcb) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr C1_1 C2 Pkinase_C Kinase-like ABC1 CEP76-C2 Motif Other DBs NCBI-GeneID:  25023 NCBI-ProteinID:  NP_001165776 RGD:  3396 Ensembl:  ENSRNOG00000012061 UniProt:  P68403 Structure PDB LinkDB All DBs Position 1:176832173..177163539 Genome browser AA seq 671 aa AA seqDB search MADPAAGPPPSEGEESTVRFARKGALRQKNVHEVKNHKFTARFFKQPTFCSHCTDFIWGL GLQGFQSQVCCFVVHKRCHEFVTFSCPGADKGPASDDPRSKHKFKIHTYSSPTFCDHCGS LLYGLIHQGMKCDTCMMNVHKRCVMNVPSLCGTDHTERRGRIYIQAHIDREVLIVVVRDA KNLVPMDPNGLSDPYVKLKLIPDPKSESKQKTKTIKCSLNPEWNETFRFQLKESDKDRRL SVEIWDWDLTSRNDFMGSLSFGISELQKAGVDGWFKLLSQEEGEYFNVPVPPEGSEGNEE LRQKFERAKIGQGTKAPEEKTANTISKFDNNGNRDRMKLTDFNFLMVLGKGSFGKVMLSE RKGTDELYAVKILKKDVVIQDDDVECTMVEKRVLALPGKPPFLTQLHSCFQTMDRLYFVM EYVNGGDLMYHIQQVGRFKEPHAVFYAAEIAIGLFFLQSKGIIYRDLKLDNVMLDSEGHI KIADFGMCKENIWDGVTTKTFCGTPDYIAPEIIAYQPYGKSVDWWAFGVLLYEMLAGQAP FEGEDEDELFQSIMEHNVAYPKSMSKEAVAICKGLMTKHPGKRLGCGPEGERDIKEHAFF RYIDWEKLERKEIQPPYKPKARDKRDTSNFDKEFTRQPVELTPTDKLFIMNLDQNEFAGF SYTNPEFVINV NT seq 2016 nt NT seq  +upstreamnt  +downstreamnt atggctgacccggctgcggggccgccgccgagcgagggcgaggagagcacggtgcgcttc gcccgcaaaggcgccctccggcagaagaacgtgcacgaggtgaagaaccacaaattcacc gcccgcttcttcaagcagcccaccttctgcagccactgcaccgacttcatttggggctta ggtttgcagggattccagagtcaggtctgctgctttgttgtacacaagcgctgccatgaa ttcgtcacgttctcctgccctggtgcagacaagggcccggcctctgatgacccacggagc aaacacaagtttaagatccacacctactccagccctaccttctgtgaccactgtggatca ctgctgtatgggctcatccaccaggggatgaaatgcgacacctgtatgatgaatgtccac aagcgctgcgtgatgaacgtccccagcctctgtggcaccgaccacacagaacgccgtggc cgcatctacatccaggcccacatcgacagggaggtcctcatcgttgttgtaagagatgct aaaaatctggtacctatggaccccaacggcttgtcagatccctacgtaaaactgaaactg atccctgatcccaaaagtgagagcaagcagaagaccaagactatcaaatgctccctcaac ccggagtggaacgaaaccttcagatttcagctgaaggaatcagacaaagacagaagactg tccgtagagatctgggattgggacctgaccagcaggaatgacttcatgggatctctgtcg tttgggatttcagaactacagaaagccggagtggatggctggttcaagttactaagccag gaagaaggcgagtactttaatgtgccggtgccgccggaaggaagcgagggcaatgaagag ctgcggcagaagtttgagagagccaagattggccaaggtaccaaggctccagaagaaaag acagcgaacactatatccaaatttgacaacaatggcaacagggaccggatgaaactgacc gattttaacttcctgatggtgctggggaaaggcagctttggcaaggtcatgctctcagag cggaagggtacagatgaactctatgccgtgaagatcctgaagaaagatgtggtgatccaa gatgacgatgtggagtgcacaatggtggagaagagggtgctggccctgcctgggaagccc ccattcctgactcagctccattcctgcttccagaccatggaccgcctctactttgtgatg gagtatgtgaacgggggcgacctcatgtaccacatccaacaagttggccgtttcaaggag ccccatgctgtattttacgctgcagagattgccatcggtcttttcttcttgcagagcaag ggcatcatttaccgtgacctgaaacttgacaacgtgatgctggattccgaggggcacatc aaaatcgctgactttggcatgtgtaaagagaatatctgggatggggtgacaaccaagaca ttctgtggcactccagactacattgccccagagatcattgcttatcagccctacgggaag tctgtggactggtgggcgtttggagtcctgctgtatgaaatgttggctggccaggcacct tttgaaggggaggatgaggatgaactcttccagtcaatcatggagcacaacgtggcgtat cccaagtccatgtctaaggaagctgtggcaatctgcaaagggctaatgaccaaacaccca ggcaagcgcctgggttgtgggcctgaaggggaacgagacattaaggagcatgcatttttc cggtatatcgactgggagaaactcgaacgcaaggagattcagccaccttataaaccaaaa gctagagacaagcgagacacctccaacttcgacaaagagttcaccaggcagcctgtggaa ctgactcccactgacaaactcttcatcatgaacttggaccaaaatgaatttgctggcttc tcgtatactaacccagagtttgtcattaatgtgtag

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