Rattus norvegicus (rat): 288227
Help
Entry
288227 CDS
T01003
Symbol
Bace2
Name
(RefSeq) beta-secretase 2 precursor
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
288227 (Bace2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rno01002
]
288227 (Bace2)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
288227 (Bace2)
Peptidases and inhibitors [BR:
rno01002
]
Aspartic peptidases
Family A1: pepsin family
288227 (Bace2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
288227
NCBI-ProteinID:
NP_001002802
RGD:
1303241
Ensembl:
ENSRNOG00000001953
UniProt:
Q6IE75
LinkDB
All DBs
Position
11:36707473..36789550
Genome browser
AA seq
514 aa
AA seq
DB search
MGALLRALLLPLLAQWLLRAVPVLAPAPFTLPLQVAGAANHRASTVPGLGTPELPRADGL
ALALEPARATANFLAMVDNLQGDSGRGYYLEMLIGTPPQKVRILVDTGSSNFAVAGAPHS
YIDTYFDSESSSTYHSKGFEVTVKYTQGSWTGFVGEDLVTIPKGFNSSFLVNIATIFESE
NFFLPGIKWNGILGLAYAALAKPSSSLETFFDSLVAQAKIPDIFSMQMCGAGLPVAGSGT
NGGSLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDS
GTTLLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGAQLACWTNSETPWAYFPKISIYLRD
ENASRSFRITILPQLYIQPMMGAGFNYECYRFGISSSTNALVIGATVMEGFYVVFDRAQR
RVGFAVSPCAEIAGTTVSEISGPFSTEDIASNCVPAQALNEPILWIVSYALMSVCGAILL
VLILLLLFPLHCRHAPRDPEVVNDESSLVRHRWK
NT seq
1545 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgctgcttcgagcactcttgctcccactgctggcgcagtggctcttgcgcgcg
gtccccgtgctggccccggcgcccttcacgcttcccctccaagtggccggggccgcgaac
cacagagcctcaactgttcccgggctcgggacccccgagttgccccgggctgatggcctg
gccctcgcactggagcctgccagggctaccgccaacttcttggctatggtggacaatctt
cagggggactctggccgcggctactacctggagatgctgattgggacccctccgcaaaag
gtacggattcttgtggacaccggaagcagtaacttcgcagtggcaggtgccccacactcc
tacatagacacctactttgactcagagagctccagcacataccactccaagggctttgag
gtcacggtgaagtacacacagggaagctggactggatttgttggtgaggaccttgtcacc
atcccaaaaggcttcaacagctctttcttggtcaatattgccactattttcgagtctgag
aatttctttttgcctgggattaagtggaatggaatccttggactcgcttatgctgccttg
gccaagccatcaagctctctggagactttttttgattccctggtggcccaagcaaaaatt
ccggacattttctccatgcagatgtgcggggctggattgccagtagctggatctggtacc
aacggaggtagtcttgtcctgggtgggattgaaccaagtttgtataaaggagatatatgg
tataccccaattaaagaggaatggtactatcaaatagagatcttgaaattggaaattgga
ggccagagcctcaacctggactgcagagagtataacgcagacaaggccattgtggacagc
ggcaccacactcctgcgcctgccccagaaggtgtttgatgcagtggtggaagccgtggca
cgcacatctctgattccagagttttctgatggcttctggacgggggcccagctggcatgc
tggacaaattctgaaactccatgggcgtatttccctaagatttctatctacctgagagat
gagaacgccagtcgctccttccgaatcaccattctgccgcagctctacattcagcccatg
atgggagctggtttcaattatgagtgctaccgttttggtatctcctcttccacaaatgcg
ctggtgattggtgccaccgtgatggagggattctacgtggtctttgacagagctcagagg
agggtgggctttgcagtgagtccctgtgcagagattgcaggtaccacagtgtctgaaatt
tctgggcccttttccacggaagacatagccagcaactgtgttccagcacaggctctgaat
gagcccatcttgtggattgtgtcctatgccctgatgagtgtgtgtggagccattctcctg
gttctgatcctcctgctgctgttcccgctgcactgccgacacgccccccgagaccctgag
gtggttaacgatgaatcctcactagtcagacatcgctggaaatga
Rattus norvegicus (rat): 29392
Help
Entry
29392 CDS
T01003
Symbol
Bace1
Name
(RefSeq) beta-secretase 1 precursor
KO
K04521
beta-site APP-cleaving enzyme 1 (memapsin 2) [EC:
3.4.23.46
]
Organism
rno
Rattus norvegicus (rat)
Pathway
rno05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
rno00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
29392 (Bace1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
rno01002
]
29392 (Bace1)
Enzymes [BR:
rno01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.46 memapsin 2
29392 (Bace1)
Peptidases and inhibitors [BR:
rno01002
]
Aspartic peptidases
Family A1: pepsin family
29392 (Bace1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
29392
NCBI-ProteinID:
NP_062077
RGD:
2191
Ensembl:
ENSRNOG00000016847
UniProt:
P56819
LinkDB
All DBs
Position
8:46142060..46166268
Genome browser
AA seq
501 aa
AA seq
DB search
MAPALRWLLLWVGSGMLPAQGTHLGIRLPLRSGLAGPPLGLRLPRETDEEPEEPGRRGSF
VEMVDNLRGKSGQGYYVEMTVGSPPQTLNILVDTGSSNFAVGAAPHPFLHRYYQRQLSST
YRDLRKSVYVPYTQGKWEGELGTDLVSIPHGPNVTVRANIAAITESDKFFINGSNWEGIL
GLAYAEIARPDDSLEPFFDSLVKQTHIPNIFSLQLCGAGFPLNQTEALASVGGSMIIGGI
DHSLYTGSLWYTPIRREWYYEVIIVRVEINGQDLKMDCKEYNYDKSIVDSGTTNLRLPKK
VFEAAVKSIKAASSTEKFPDGFWLGEQLVCWQAGTTPWNIFPVISLYLMGEVTNQSFRIT
ILPQQYLRPVEDVATSQDDCYKFAVSQSSTGTVMGAVIMEGFYVVFDRARKRIGFAVSAC
HVHDEFRTAAVEGPFVTADMEDCGYNIPQTDESTLMTIAYVMAAICALFMLPLCLMVCQW
RCLRCLRHQHDDFADDISLLK
NT seq
1506 nt
NT seq
+upstream
nt +downstream
nt
atggccccggcgctgcgctggctcctgctatgggtgggctcgggaatgctgcctgcccag
ggaacccatctcggtatccgactgccccttcgcagcggcctggcagggccacccctgggc
ctgaggctgccccgggagacggacgaggaacctgaggagcctggccggagaggcagcttt
gtggagatggtggacaacctgaggggaaagtccggccagggctactatgtggagatgacc
gtgggcagccccccacagacgctcaacatcctggtggacacgggcagtagtaattttgca
gtgggggctgccccacaccctttcctgcatcgatactaccaaaggcagctgtccagtaca
taccgagacctccgaaagtctgtgtatgtgccctacacccagggcaagtgggagggggaa
ctgggcactgacctggtgagcatccctcatggccccaacgtcactgtgcgtgccaacatt
gctgccatcactgaatcggacaagttcttcatcaatggttccaactgggagggcatccta
gggctggcctatgctgagattgccaggcctgacgactccttggagcccttttttgactcc
ctggtgaagcagacccacattccgaacatcttttccctgcagctctgtggcgctggcttc
cccctcaaccagactgaggcactggcctcggtgggagggagcatgatcattggtggtatc
gaccattccctatacactggcagtctctggtacacacccatccggcgggagtggtattat
gaagtgatcattgtacgtgtagaaatcaatggtcaagatctgaaaatggactgcaaggag
tacaactatgacaagagcatcgtggacagtggcaccaccaaccttcgtttgcccaagaaa
gtatttgaagctgcagtcaagtccatcaaggcagcctcctcgacggagaagttcccggat
ggcttttggctaggggagcagctggtgtgctggcaagcaggcacgaccccttggaacatt
ttcccagtcatttcactttacctcatgggtgaagtcaccaatcagtccttccgcatcacc
atccttcctcagcaatacctacggccagtggaagatgtggccacgtcccaagacgactgt
tacaagttcgccgtctcacagtcatccacaggcaccgttatgggagcggtcatcatggaa
ggcttctatgtggtctttgatcgagcccgaaagcgaattggctttgctgtcagcgcttgc
catgtgcacgatgagttcaggacggcggcagtggaaggtccgtttgtcacggcagacatg
gaagactgtggctacaacattccacagacagatgagtcgacacttatgaccatagcctat
gtcatggctgccatctgcgccctcttcatgttgccactctgcctcatggtatgtcagtgg
cgctgcctacgctgcctgcgccatcagcatgatgactttgctgatgacatctccctgctg
aaataa
DBGET
integrated database retrieval system
