KEGG   Rattus norvegicus (rat): 29192
Entry
29192             CDS       T01003                                 
Symbol
Psen1
Name
(RefSeq) presenilin-1
  KO
K04505  presenilin 1 [EC:3.4.23.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04310  Wnt signaling pathway
rno04330  Notch signaling pathway
rno04722  Neurotrophin signaling pathway
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
rno05165  Human papillomavirus infection
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    29192 (Psen1)
   04330 Notch signaling pathway
    29192 (Psen1)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    29192 (Psen1)
 09160 Human Diseases
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    29192 (Psen1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    29192 (Psen1)
   05022 Pathways of neurodegeneration - multiple diseases
    29192 (Psen1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    29192 (Psen1)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.-
     29192 (Psen1)
Peptidases and inhibitors [BR:rno01002]
 Aspartic peptidases
  Family A22: presenilin family
   29192 (Psen1)
SSDB
Motif
Pfam: Presenilin
Other DBs
NCBI-GeneID: 29192
NCBI-ProteinID: NP_062036
RGD: 3425
Ensembl: ENSRNOG00000009110
UniProt: P97887
LinkDB
Position
6:103323014..103375088
AA seq 468 aa
MTEIPAPLSYFQNAQMSEDSHSSSVRSQNDNQERQQHHDRQRLDNPESISNGRPQSNFTR
QVIEQDEEEDEELTLKYGAKHVIMLFVPVTLCMVVVVATIKSVSFYTRKDGQLIYTPFTE
DTETVGQRALHSILNAAIMISVIVVMTILLVVLYKYRCYKVIHAWLIVSSLLLLFFFSFI
YLGEVFKTYNVAVDYITVALLIWNFGVVGMIAIHWKGPLRLQQAYLIMISALMALVFIKY
LPEWTAWLILAVISVYDLVAVLCPKGPLRMLVETAQERNETLFPALIYSSTMVWLVNMAE
GDPEAQRRVPKNPKYSTQGTEREETQDTGTGSDDGGFSEEWEAQRDSHLGPHRSTPESRA
AVQELSGSILTSEDPEERGVKLGLGDFIFYSVLVGKASATASGDWNTTIACFVAILIGLC
LTLLLLAIFKKALPALPISITFGLIFYFATDYLVQPFMDQLAFHQFYI
NT seq 1407 nt   +upstreamnt  +downstreamnt
atgacagagatacctgcacctttgtcctacttccagaatgcacagatgtctgaggacagc
cactccagcagcgtccgtagccagaatgacaatcaagaacggcagcagcatcatgacaga
cagagacttgacaaccctgagtcgatatctaatggccgaccccagagtaactttaccagg
caggtgatagagcaagatgaggaggaagacgaagagctgacattgaaatatggagccaag
cacgtcatcatgctctttgttcctgtgaccctctgcatggtcgttgtggtggccaccatc
aagtcagtcagcttctacacccggaaggatgggcagctaatctataccccattcacagaa
gacaccgagactgtaggccagagagccctgcactcgatcttgaatgccgccatcatgatc
agtgtcatcgtcgttatgaccatcctcctggtggtcctgtataagtacaggtgctacaag
gtcatccatgcctggcttattgtttcatctctgttgttgctgttctttttttcattcatt
tacttaggggaagtattcaagacctacaatgtcgccgtggactatattacggttgcactc
ctgatctggaattttggtgtggtcgggatgattgccattcactggaaaggcccactccga
ctgcagcaggcgtatctcattatgatcagtgccctcatggccctggtatttatcaagtac
ctccctgaatggaccgcatggctcatcttggctgtgatttcagtatatgatttggtggct
gttctgtgccccaaaggtccacttcgtatgctggtcgaaacagctcaggaaagaaatgag
actctctttccagctcttatctattcctcaaccatggtgtggttggtgaatatggctgaa
ggagacccagaagcccaaaggagggtacccaaaaaccccaagtatagcacacaaggaaca
gagagggaagagacacaggacactggcactgggagcgatgatggtggcttcagtgaggag
tgggaggcccaaagagacagtcacctggggcctcatcgctccactcctgagtcaagagct
gctgtccaggaactttctgggagcatcctcactagtgaagacccggaggaaagaggagta
aagcttgggctgggagatttcattttctacagtgttctggttggtaaggcctcagcgacc
gccagtggggactggaacacaaccatagcctgctttgtagccatattgatcggcctgtgc
cttacgttactcctgctcgccattttcaagaaagcgttgccggcccttcccatctccatc
accttcgggctcattttctactttgccacggattatctcgtgcagcccttcatggaccaa
cttgcattccatcaattttatatctag

KEGG   Rattus norvegicus (rat): 81751
Entry
81751             CDS       T01003                                 
Symbol
Psen2
Name
(RefSeq) presenilin-2
  KO
K04522  presenilin 2 [EC:3.4.23.-]
Organism
rno  Rattus norvegicus (rat)
Pathway
rno04330  Notch signaling pathway
rno04722  Neurotrophin signaling pathway
rno05010  Alzheimer disease
rno05022  Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:rno00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    81751 (Psen2)
 09150 Organismal Systems
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    81751 (Psen2)
 09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    81751 (Psen2)
   05022 Pathways of neurodegeneration - multiple diseases
    81751 (Psen2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:rno01002]
    81751 (Psen2)
Enzymes [BR:rno01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.23  Aspartic endopeptidases
    3.4.23.-
     81751 (Psen2)
Peptidases and inhibitors [BR:rno01002]
 Aspartic peptidases
  Family A22: presenilin family
   81751 (Psen2)
SSDB
Motif
Pfam: Presenilin
Other DBs
NCBI-GeneID: 81751
NCBI-ProteinID: NP_112349
RGD: 621060
Ensembl: ENSRNOG00000002879
UniProt: O88777
LinkDB
Position
13:complement(91967506..91993240)
AA seq 448 aa
MLTFMASDSEEEVCDERTSLMSAESPTSRSCQDSRPGPEDGENTAQWRSQENEDDCEEDP
DHYACSGVPGRPSGLEEELTLKYGAKHVIMLFVPVTLCMIVVVATIKSVRFYTEKNGQLI
YTPFTEDTPSVGQRLLNSVLNTLIMISVIVVMTIFLVVLYKYRCYKFIHGWLIMSSLMLL
FLFTYIYLGEVFKTYNVAMDYPTLFLAVWNFGAVGMVCIHWKGPLVLQQAYLIVISALMA
LVFIKYLPEWSAWVILGAISVYDLVAVLCPKGPLRMLVETAQERNEPIFPALIYSSAMVW
TVGMAKLDPSSQGALQLPYDPEMEEDSYDSFGEPSYPEAFEAPQPGYPGEEPEEEEERGV
KLGLGDFIFYSVLVGKAAATGNGDWSTTLACFIAILIGLCLTLLLLAVFKKALPALPISI
TFGLIFYFSTDNLVRPFMDTLASHQLYI
NT seq 1347 nt   +upstreamnt  +downstreamnt
atgctcacattcatggcctctgatagcgaggaagaggtgtgcgatgagcggacgtccttg
atgtcagccgagagccctacatcacgttcctgccaggacagcaggccaggcccagaggat
ggagagaacactgcccagtggaggagccaggagaacgaggacgactgtgaggaggacccg
gaccactatgcctgcagtggggttcctgggcgaccatcgggcctggaggaggagctgacc
ctcaagtatggggcgaagcacgtgatcatgctgttcgtgcctgtcacgctgtgcatgatt
gtggtggtggccaccatcaagtccgtgcgtttctacacggagaagaacgggcagctcatc
tacacgcccttcaccgaggacacaccctctgtgggccagcggctcctcaactccgtgctg
aacactctgatcatgatcagcgtcattgtggtcatgactatcttcctagtggtactctac
aaatatcgctgttacaagttcatccatggctggctgatcatgtcctccctgatgctcctc
ttcttgttcacctacatctacctcggggaagtgttcaagacctacaatgtggccatggac
taccccacactgttcctggctgtctggaacttcggggcagtgggcatggtgtgcatccac
tggaagggtcccctggtgctccagcaggcttacctcattgtgatcagcgcactcatggcc
ctggtgttcatcaagtacctgccggagtggtccgcttgggtcatcttgggcgccatctct
gtgtacgatctcgtggctgtgctgtgccccaaagggccactgaggatgctggtggaaact
gcccaggaaagaaacgagcccatatttcctgccctcatatactcatctgccatggtgtgg
acggtaggcatggcgaagctggacccctcctctcagggagcactgcagctcccttacgat
ccagagatggaagaagactcctatgacagttttggggaaccctcataccctgaagccttc
gaagctccccagcctggctacccaggggaagagccggaggaggaggaggaaaggggtgta
aagcttggtctgggagacttcatcttctacagcgttctggtgggcaaggcagcagccaca
ggcaacggagactggagcacgacgctggcctgctttatcgccatcctcattggcttgtgt
ctcaccctcctgctgctcgccgtgttcaagaaggccctgcccgccctccccatctccatc
accttcgggctcatcttttacttctccacagacaacctggtgcgtcctttcatggacacg
ttggcctcccaccagctctacatctga

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