Rattus norvegicus (rat): 29260 Help Entry 29260             CDS       T01003                                  Symbol Tlr4 Name (RefSeq) toll-like receptor 4 precursor   KO K10160   toll-like receptor 4 Organism rno  Rattus norvegicus (rat) Pathway rno04064   NF-kappa B signaling pathway rno04066   HIF-1 signaling pathway rno04145   Phagosome rno04151   PI3K-Akt signaling pathway rno04217   Necroptosis rno04613   Neutrophil extracellular trap formation rno04620   Toll-like receptor signaling pathway rno04621   NOD-like receptor signaling pathway rno04936   Alcoholic liver disease rno05132   Salmonella infection rno05133   Pertussis rno05134   Legionellosis rno05135   Yersinia infection rno05140   Leishmaniasis rno05142   Chagas disease rno05144   Malaria rno05145   Toxoplasmosis rno05146   Amoebiasis rno05152   Tuberculosis rno05161   Hepatitis B rno05162   Measles rno05164   Influenza A rno05170   Human immunodeficiency virus 1 infection rno05171   Coronavirus disease - COVID-19 rno05205   Proteoglycans in cancer rno05235   PD-L1 expression and PD-1 checkpoint pathway in cancer rno05321   Inflammatory bowel disease rno05323   Rheumatoid arthritis rno05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     29260 (Tlr4)    04066 HIF-1 signaling pathway     29260 (Tlr4)    04151 PI3K-Akt signaling pathway     29260 (Tlr4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     29260 (Tlr4)   09143 Cell growth and death    04217 Necroptosis     29260 (Tlr4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     29260 (Tlr4)    04620 Toll-like receptor signaling pathway     29260 (Tlr4)    04621 NOD-like receptor signaling pathway     29260 (Tlr4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     29260 (Tlr4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     29260 (Tlr4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     29260 (Tlr4)    05161 Hepatitis B     29260 (Tlr4)    05171 Coronavirus disease - COVID-19     29260 (Tlr4)    05164 Influenza A     29260 (Tlr4)    05162 Measles     29260 (Tlr4)   09171 Infectious disease: bacterial    05132 Salmonella infection     29260 (Tlr4)    05135 Yersinia infection     29260 (Tlr4)    05133 Pertussis     29260 (Tlr4)    05134 Legionellosis     29260 (Tlr4)    05152 Tuberculosis     29260 (Tlr4)   09174 Infectious disease: parasitic    05146 Amoebiasis     29260 (Tlr4)    05144 Malaria     29260 (Tlr4)    05145 Toxoplasmosis     29260 (Tlr4)    05140 Leishmaniasis     29260 (Tlr4)    05142 Chagas disease     29260 (Tlr4)   09163 Immune disease    05323 Rheumatoid arthritis     29260 (Tlr4)    05321 Inflammatory bowel disease     29260 (Tlr4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     29260 (Tlr4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     29260 (Tlr4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     29260 (Tlr4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:rno04054]     29260 (Tlr4)    04090 CD molecules [BR:rno04090]     29260 (Tlr4)    00536 Glycosaminoglycan binding proteins [BR:rno00536]     29260 (Tlr4) Membrane trafficking [BR:rno04131]  Endocytosis   Phagocytosis    Toll-like receptors     29260 (Tlr4) Pattern recognition receptors [BR:rno04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    29260 (Tlr4) CD molecules [BR:rno04090]  Proteins   29260 (Tlr4) Glycosaminoglycan binding proteins [BR:rno00536]  Hyaluronan   Cell surface receptors    29260 (Tlr4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 TIR LRR_4 TIR_2 LRR_9 DUF1863 Motif Other DBs NCBI-GeneID:  29260 NCBI-ProteinID:  NP_062051 RGD:  3870 Ensembl:  ENSRNOG00000010522 UniProt:  Q9QX05 G3V7D8 LinkDB All DBs Position 5:80145867..80159501 Genome browser AA seq 835 aa AA seqDB search MMPLLHLAGTLIMALFLSCLRPGSLNPCIEVLPNITYQCMDQNLSKIPHDIPYSTKNLDL SFNPLKILRSYSFSNFSQLQWLDLSRCEIETIEDKAWHGLNQLSTLVLTGNPIKSFSPGS FSGLTNLENLVAVETKMTSLEGFHIGQLISLKKLNVAHNLIHSFKLPEYFSNLTNLEHVD LSYNYIQTISVKDLQFLRENPQVNLSLDLSLNPIDSIQAQAFQGIRLHELTLRSNFNSSN VLKMCLQNMTGLHVHRLILGEFKNERNLESFDRSVMEGLCNVSIDEFRLTYINHFSDDIY NLNCLANISAMSFTGVHIKHIADVPRHFKWQSLSIIRCHLKPFPKLSLPFLKSWTLTTNR EDISFGQLALPSLRYLDLSRNAMSFRGCCSYSDFGTNNLKYLDLSFNGVILMSANFMGLE ELEYLDFQHSTLKKVTEFSVFLSLEKLLYLDISYTNTKIDFDGIFLGLISLNTLKMAGNS FKDNTLSNVFTNTTNLTFLDLSKCQLEQISRGVFDTLYRLQLLNMSHNNLLFLDPSHYKQ LYSLRTLDCSFNRIETSKGILQHFPKSLAVFNLTNNSVACICEYQNFLQWVKDQKMFLVN VEQMKCASPIDMKASLVLDFTNSTCYIYKTIISVSVVSVLVVATVAFLIYHFYFHLILIA GCKKYSRGESIYDAFVIYSSQNEDWVRNELVKNLEEGVPRFQLCLHYRDFIPGVAIAANI IQEGFHKSRKVIVVVSRHFIQSRWCIFEYEIAQTWQFLSSRSGIIFIVLEKVEKSLLRQQ VELYRLLSRNTYLEWEDNALGRHIFWRRLKKALLDGKALNPDETSEEEQEATTLT NT seq 2508 nt NT seq  +upstreamnt  +downstreamnt atgatgcctctcttgcatctggctgggactctgatcatggcattgttcctttcctgcctg agaccaggaagcttgaatccctgcatagaggtacttcctaatattacctaccaatgcatg gatcagaatctcagcaaaatccctcatgacatcccttattcaaccaagaacctagatctg agcttcaaccccctgaagatcttaagaagctatagcttctccaatttctcacaacttcag tggctggatttatccaggtgtgaaattgagacaattgaagacaaggcatggcatggctta aaccagctctcaaccttggtactgacaggaaaccctatcaagagtttttccccaggaagt ttttctggactaacaaatttagagaatctggtggctgtggagacaaaaatgacctctcta gagggtttccatattggacagcttatatccttaaagaaactaaatgtggctcataatctt atacattcctttaagttacctgaatatttttctaatctgacaaacctagaacatgtggat ctttcttataactatattcaaactatttctgtcaaagacttacagtttctacgtgaaaat ccccaagtcaatctctctttagacctgtctttaaacccaattgactccattcaagcccaa gcctttcagggaattaggctccatgaattgactctaagaagtaattttaatagctcaaat gtactgaaaatgtgccttcaaaacatgactggtttacatgtccatcggttgatcttggga gaatttaaaaatgaaaggaatctggaaagttttgaccgttctgtcatggaaggactatgc aatgtgagcattgatgagttcaggttaacatatataaatcatttttcagatgatatttat aatctcaattgcttggcaaatatttctgcaatgtctttcacaggtgtacatataaaacac atagcagatgttcctagacatttcaaatggcaatccttatcaatcattagatgtcatctt aagccttttccaaagctgagtctaccttttcttaaaagttggactttaactaccaacaga gaggatatcagctttggtcagttggctctgccaagtctcagatatctagatcttagtaga aatgccatgagctttagaggttgctgttcttattctgattttggaacaaacaacctgaag tacttagacctcagcttcaatggtgtcatcctgatgagtgccaacttcatgggtctagaa gagctggaatacctggactttcagcactccactttaaaaaaggtcacagaattctcagtg ttcttatctcttgaaaaacttctttaccttgacatctcttacactaataccaaaattgac tttgatggcatatttcttggcttgatcagtctcaacactttaaaaatggctggcaattct ttcaaagacaacaccctttcaaatgtctttacaaacacaacaaacttaacattcctggat ctttctaaatgccaactggaacagatatctaggggggtatttgacacactctacagactc cagttattaaacatgagtcacaacaacctactgtttctggatccatcccattataaacag ctgtactccctcaggactcttgattgcagtttcaatcgcatagagacatccaaaggaata ctgcaacattttccaaagagtctagccgtcttcaatctgactaataattctgttgcttgt atatgtgaatatcagaatttcttgcagtgggtcaaggaccagaaaatgttcttggtgaat gttgaacaaatgaaatgtgcatcacctatagacatgaaggcctccctggtgttggatttt acgaattccacctgttatatatacaagactatcatcagtgtatcggtggtcagtgtgctt gtggtagccactgtagcatttctgatataccacttctattttcacctgatacttattgct ggctgtaaaaagtacagcagaggagaaagcatctatgatgcatttgtgatctactcgagc cagaatgaggactgggtgagaaacgagctggtaaagaatttagaagaaggagtgccccgc tttcagctttgccttcattacagggactttattcctggtgtagccattgctgccaacatc atccaggaaggcttccacaagagccggaaagttattgtggtggtgtctagacactttatc cagagccgttggtgtatctttgaatatgagattgctcagacatggcagtttctgagtagc cgctctggcatcatcttcattgtccttgagaaagtggagaagtccttgctgaggcagcag gtcgaattgtatcgccttcttagcagaaacacctacctcgagtgggaggacaatgctctg gggaggcacatcttctggagaagactcaaaaaagccctgttggatggaaaagccttgaat ccagatgaaacatcagaggaagaacaagaagcaacaactttgacctga

Rattus norvegicus (rat): 310553 Help Entry 310553            CDS       T01003                                  Symbol Tlr2 Name (RefSeq) toll-like receptor 2 precursor   KO K10159   toll-like receptor 2 Organism rno  Rattus norvegicus (rat) Pathway rno04145   Phagosome rno04151   PI3K-Akt signaling pathway rno04613   Neutrophil extracellular trap formation rno04620   Toll-like receptor signaling pathway rno05132   Salmonella infection rno05134   Legionellosis rno05140   Leishmaniasis rno05142   Chagas disease rno05144   Malaria rno05145   Toxoplasmosis rno05146   Amoebiasis rno05152   Tuberculosis rno05161   Hepatitis B rno05162   Measles rno05168   Herpes simplex virus 1 infection rno05169   Epstein-Barr virus infection rno05170   Human immunodeficiency virus 1 infection rno05171   Coronavirus disease - COVID-19 rno05205   Proteoglycans in cancer rno05235   PD-L1 expression and PD-1 checkpoint pathway in cancer rno05321   Inflammatory bowel disease rno05323   Rheumatoid arthritis rno05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04151 PI3K-Akt signaling pathway     310553 (Tlr2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     310553 (Tlr2)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     310553 (Tlr2)    04620 Toll-like receptor signaling pathway     310553 (Tlr2)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     310553 (Tlr2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     310553 (Tlr2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     310553 (Tlr2)    05161 Hepatitis B     310553 (Tlr2)    05171 Coronavirus disease - COVID-19     310553 (Tlr2)    05162 Measles     310553 (Tlr2)    05168 Herpes simplex virus 1 infection     310553 (Tlr2)    05169 Epstein-Barr virus infection     310553 (Tlr2)   09171 Infectious disease: bacterial    05132 Salmonella infection     310553 (Tlr2)    05134 Legionellosis     310553 (Tlr2)    05152 Tuberculosis     310553 (Tlr2)   09174 Infectious disease: parasitic    05146 Amoebiasis     310553 (Tlr2)    05144 Malaria     310553 (Tlr2)    05145 Toxoplasmosis     310553 (Tlr2)    05140 Leishmaniasis     310553 (Tlr2)    05142 Chagas disease     310553 (Tlr2)   09163 Immune disease    05323 Rheumatoid arthritis     310553 (Tlr2)    05321 Inflammatory bowel disease     310553 (Tlr2)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     310553 (Tlr2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     310553 (Tlr2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:rno04147]     310553 (Tlr2)    04054 Pattern recognition receptors [BR:rno04054]     310553 (Tlr2)    04090 CD molecules [BR:rno04090]     310553 (Tlr2)    00536 Glycosaminoglycan binding proteins [BR:rno00536]     310553 (Tlr2) Membrane trafficking [BR:rno04131]  Endocytosis   Phagocytosis    Toll-like receptors     310553 (Tlr2) Exosome [BR:rno04147]  Exosomal proteins   Exosomal proteins of breast milk    310553 (Tlr2) Pattern recognition receptors [BR:rno04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    310553 (Tlr2) CD molecules [BR:rno04090]  Proteins   310553 (Tlr2) Glycosaminoglycan binding proteins [BR:rno00536]  Hyaluronan   Cell surface receptors    310553 (Tlr2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 LRR_4 TIR TIR_2 LRR_5 LRR_1 LRR_9 LRRCT PhoR Motif Other DBs NCBI-GeneID:  310553 NCBI-ProteinID:  NP_942064 RGD:  735138 Ensembl:  ENSRNOG00000009822 UniProt:  Q6YGU2 LinkDB All DBs Position 2:complement(169200620..169206819) Genome browser AA seq 784 aa AA seqDB search MLQALWLFWILMAVIGLSREGHSAQASLSCDAAGVCDGSSRSFTSIPSGLTANTKKLDLS FNKITYIGHGDLRACVNLRVLTLESSGINTIEGDAFYSLGSLEHLDLSNNHLSSLSSSWF RPLSSLKYLNLMGNPYRTLGETSLFSNLTNLQTLRVGNVDTFSEIRRIDFAGLTSLNELE IQVLSLGNYESRSLQSIRDIYHLTLHLSESAFLLGIFADILSSVRYLELRDTNLARFQFS ELSVDEINSPMKKLAFRNADLTDKSFNELLKLLRYILELMEVEFDHCTLNGVGNFNPSES DVVRELGKVETVTIRSLHIPQFYLFYDLSTVYSLLEKVKRITVENSKVFLVPCSFSQHLK SLEFLDLSENLMVEEYLKNSACEGGWPSLQSLVLSQNHLRSIRKTAEILLTLKNLTALDI SKNSFQPMPDSCQWPGKMRFLNLSSTGIQAVKTCIPQTLEVLDVSNNNLDSFSLFLPRLQ ELYISRNKLKTLPEASLFPVLQVMKIRENAISTFSKDQLGSFPKLETLEAGDNHFICSCE LLSFILERPALVHVLVDWPDSYLCDSPPRLHGQRLQDARPSVLECHQAALVSGVCCALLL LILLLGALCYHFHGLWYLRMMWAWLRAKRKPKKAPCRDLCYDAFVSYSEQDSYWVENLMV QQLENSDPPFKLCLHKRDFVPGKWIIDNIIDSIEKSHKTVFVLSENFVRSEWCKYELDFS HFRLFDENNDAAILVLLEPIEKKAIPQRFCKLRKIMNTKTYLEWPLDEGQREVFWANLRT AIKS NT seq 2355 nt NT seq  +upstreamnt  +downstreamnt atgctgcaagctctttggctcttctggatcttgatggctgtgataggcctctcaagggaa ggccattctgcccaggcatctctgtcatgtgatgctgctggtgtgtgtgatggcagctcc aggtctttcacctctattccctcgggactcacagcaaacacaaagaagcttgacctgtct ttcaacaagatcacctacattggccatggtgacttgcgagcctgtgtgaacctccgggtt ctgacattggagtccagcggaatcaacacaatagagggagatgccttttattctctgggc agtcttgaacacttggacttgtctaataatcacctatctagtttatcttcctcctggttc aggcccctttcctctttgaaatacttaaacttaatgggaaatccttacaggacactgggg gaaacatcactgttctccaatctcacaaatttacaaacccttagggtaggaaatgttgac actttcagtgagataaggagaatagattttgctgggctgacctctctcaacgaacttgaa attcaggtattaagtctcggcaactatgagtcccgaagtctacagtcaattagagacatc tatcacctgaccctgcacttgagcgagtctgctttcctgctggggatttttgcagatatt ctgagttccgtgagatatttagaactaagagatactaacttggctaggttccaattttct gaactgtctgtagacgaaatcaattcgccaatgaagaagctggcattccggaatgcagat ctcaccgataaaagttttaatgaactcctgaagctgttgcgttacatcttggaactgatg gaggtggagtttgatcactgcaccctcaatggggttggtaatttcaacccctcagagtca gacgtagtgagggagctaggtaaagtagaaacggtaacaatacggagcctgcacatcccc cagttctatttgttctatgatctgagcactgtgtattccctcctggagaaagtgaagcga atcacagtagagaacagtaaggtctttctggttccctgctctttctcacagcatttaaaa tcattagagttcttagacctcagcgaaaatctgatggttgaagagtatttgaaaaactca gcctgtgagggtggctggccttctctacaaagcttggttttgagtcagaatcatttgaga tcaatacgaaaaactgctgagattttgctgactctgaaaaacctgacagcccttgacatc agcaagaacagttttcagcctatgcccgacagttgtcagtggccaggaaagatgcgcttc ctgaacttgtccagtacagggatacaggccgtcaagacatgcattcctcagaccctggag gtgttggatgttagtaacaacaatctcgattcattttctttgtttttgcctcggctccaa gagctgtatatttccagaaataaactgaagacactcccagaagcttcattgttccctgtg ttacaggtcatgaagatcagagagaacgcaataagtactttctctaaagaccagcttggt tcttttcccaaactggagactctggaagcaggtgacaaccatttcatctgctcctgtgaa ctcctgtccttcattctggagaggccagccctggtccatgtcctggttgactggccagac agctacctgtgtgattctccgcctcgcctgcatggccagaggcttcaggatgcccggccc tcagtcttggagtgtcaccaggccgcactggtctctggagtctgctgtgcccttctcctg ttgatcctgctcttaggcgccctgtgttaccatttccatgggctgtggtatctgagaatg atgtgggcgtggctccgggccaagaggaagcccaagaaagctccttgcagggacctttgc tatgatgcctttgtttcctacagcgagcaggattcctattgggtggagaacctcatggtc cagcagctggagaactctgacccacccttcaagctgtgtctccacaagcgggactttgtt ccgggcaaatggatcattgacaacatcattgattccatcgaaaagagccacaaaactgtg ttcgtgctttctgagaacttcgtacgcagtgagtggtgcaagtatgaactggacttctcc cacttcaggctctttgacgagaacaatgacgcggccatccttgttttgctggaacccatt gagaagaaagccattccccagcgcttctgcaaactgcgcaagataatgaacactaagaca tacctggagtggcccttggatgaaggccagcgggaagtgttttgggcaaatctgagaact gcaataaaatcctag

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