Rattus norvegicus (rat): 292756 Help Entry 292756            CDS       T01003                                  Symbol Pak4 Name (RefSeq) serine/threonine-protein kinase PAK 4   KO K05734   p21-activated kinase 4 [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04360   Axon guidance rno04510   Focal adhesion rno04660   T cell receptor signaling pathway rno04810   Regulation of actin cytoskeleton rno05170   Human immunodeficiency virus 1 infection rno05206   MicroRNAs in cancer rno05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     292756 (Pak4)    04014 Ras signaling pathway     292756 (Pak4)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     292756 (Pak4)   09142 Cell motility    04810 Regulation of actin cytoskeleton     292756 (Pak4)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     292756 (Pak4)   09158 Development and regeneration    04360 Axon guidance     292756 (Pak4)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     292756 (Pak4)   09162 Cancer: specific types    05211 Renal cell carcinoma     292756 (Pak4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     292756 (Pak4)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     292756 (Pak4) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      292756 (Pak4) Protein kinases [BR:rno01001]  Serine/threonine kinases: STE group   STE20 family    292756 (Pak4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal hnRNP_Q_AcD KIND Kdo Motif Other DBs NCBI-GeneID:  292756 NCBI-ProteinID:  NP_001099708 RGD:  1307705 Ensembl:  ENSRNOG00000019883 UniProt:  B5DF62 LinkDB All DBs Position 1:complement(83849904..83889188) Genome browser AA seq 593 aa AA seqDB search MFGKKKKRVEISAPSNFEHRVHTGFDQHEQKFTGLPRQWQSLIEESARRPKPLIDPACIT SIQPGAPKTIVRGSKGAKDGALTLLLDEFENMSVTRSNSLRRESPPPPARAHQENGMLEE RAALARMAPDKAGGRGRATGHSEAGSGSGDRRRVGPEKRPKSSREGPGGPQEVSRDKRPL SGPDVSTPQPGSLASETKLAAGRPFNTYPRADTDHPPRGTQGEPHTMAPNGPSAIGLAAP QSSSSSRPPTRARGAPSPGVLGPHASEPQLAPPARALAAPAVPPAPGPPGPRSPQREPQR VSHEQFRAALQLVVDPGDPRSYLDNFIKIGEGSTGIVCIATVRSSGKLVAVKKMDLRKQQ RRELLFNEVVIMRDYRHENVVEMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMNEEQIA AVCLAVLQALSVLHAQGVIHRDIKSDSILLTHDGRVKLSDFGFCAQVSKEVPRRKSLVGT PYWMAPELISRLPYGPEVDIWSLGVMVIEMVDGEPPYFNEPPLKAMKMIRDNLPPRLKNL HKASPSLKGFLDRLLVRDPAQRATAAELLKHPFLTKAGPPASIVPLMRQHRNR NT seq 1782 nt NT seq  +upstreamnt  +downstreamnt atgtttggaaagaagaagaagcgggtggagatctcggccccatccaacttcgagcaccgc gtacacacaggcttcgatcagcatgagcagaagttcacagggctgccccgccagtggcag agcctgattgaggagtcagcgcgcagacccaagcccctgatcgaccctgcttgcatcact tccatccagcctggagcccccaagaccatcgtgcggggcagcaaaggtgccaaggatggg gctctcacactgctgcttgacgaatttgagaacatgtcggtgacacgctccaactccctg cgcagagagagtcctccaccccctgcccgcgcccatcaggaaaatggaatgctggaggag cgggcagctctggccagaatggcccctgacaaagctggaggcaggggccgggccacaggc cacagtgaggcaggcagtggcagtggtgacagacggcgggtggggccagagaagaggccc aagtcatcaagggagggcccaggagggccccaggaggtctcccgtgataagcgccccctc tctggtcctgatgtcagcactcctcagcctggcagtctggccagcgagacaaaactagca gctggcagaccctttaacacataccctcgggctgacacggaccacccaccccggggtacc cagggggagccacacaccatggcccctaatgggccatcagccataggcctggctgctcct cagtcttcctcctcctcccggcctcccacccgagcccgtggtgctcccagcccgggagtg ctgggtccccatgcctctgagccccagttggcccccccagcacgtgcccttgctgcccct gctgtaccccctgctcctgggccccctgggcctcggtcaccacagcgggagccccaacga gtatcccatgagcagttccgggccgccctgcagctagtggtggacccaggggaccctcgt tcctatctagacaacttcatcaagattggcgagggctctacaggtattgtgtgcatagcc actgtgcgaagctcgggcaaactggtggccgtcaagaagatggacttgcgtaagcagcag agacgtgagctgctcttcaatgaggtggtgatcatgagggactaccggcatgaaaacgtg gtggagatgtacaacagctacctggtaggcgatgagctctgggtggtcatggagttcctg gagggaggcgccctcacggatattgtcacccacaccaggatgaatgaggaacagattgcc gccgtgtgcctggctgtgcttcaggcgctgtctgtgctccatgcccagggcgtcatccac cgtgacatcaagagtgactccatcctgctgacccacgatggccgggtgaagctgtccgac ttcgggttttgtgcccaggtgagcaaggaggtgcctcggaggaagtcgctggtgggcacc ccatactggatggccccagagctcatctcccgccttccctacgggccagaggtggatatc tggtcactgggggtaatggtgatcgagatggtggatggggaacccccctacttcaacgag ccacccctgaaagccatgaagatgattcgggacaacctgccgccccgactgaagaacctg cacaaggcctcaccatctctgaaaggcttcttggatcgcctgctggtgcgtgacccagcc cagcgggccactgctgctgagctgctgaagcacccgttcctcaccaaggcggggccgcca gccagcattgtgccccttatgcgccagcaccgaaacagatga

Rattus norvegicus (rat): 29431 Help Entry 29431             CDS       T01003                                  Symbol Pak1 Name (RefSeq) serine/threonine-protein kinase PAK 1   KO K04409   p21-activated kinase 1 [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno04010   MAPK signaling pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04024   cAMP signaling pathway rno04062   Chemokine signaling pathway rno04360   Axon guidance rno04392   Hippo signaling pathway - multiple species rno04510   Focal adhesion rno04625   C-type lectin receptor signaling pathway rno04650   Natural killer cell mediated cytotoxicity rno04660   T cell receptor signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno04810   Regulation of actin cytoskeleton rno05132   Salmonella infection rno05170   Human immunodeficiency virus 1 infection rno05205   Proteoglycans in cancer rno05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     29431 (Pak1)    04012 ErbB signaling pathway     29431 (Pak1)    04014 Ras signaling pathway     29431 (Pak1)    04392 Hippo signaling pathway - multiple species     29431 (Pak1)    04024 cAMP signaling pathway     29431 (Pak1)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     29431 (Pak1)   09142 Cell motility    04810 Regulation of actin cytoskeleton     29431 (Pak1)  09150 Organismal Systems   09151 Immune system    04625 C-type lectin receptor signaling pathway     29431 (Pak1)    04650 Natural killer cell mediated cytotoxicity     29431 (Pak1)    04660 T cell receptor signaling pathway     29431 (Pak1)    04666 Fc gamma R-mediated phagocytosis     29431 (Pak1)    04062 Chemokine signaling pathway     29431 (Pak1)   09158 Development and regeneration    04360 Axon guidance     29431 (Pak1)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     29431 (Pak1)   09162 Cancer: specific types    05211 Renal cell carcinoma     29431 (Pak1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     29431 (Pak1)   09171 Infectious disease: bacterial    05132 Salmonella infection     29431 (Pak1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     29431 (Pak1)   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:rno04131]     29431 (Pak1)    03036 Chromosome and associated proteins [BR:rno03036]     29431 (Pak1) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      29431 (Pak1) Protein kinases [BR:rno01001]  Serine/threonine kinases: STE group   STE20 family    29431 (Pak1) Membrane trafficking [BR:rno04131]  Exocytosis   Calcium ion-dependent exocytosis    Kinases and associated proteins     29431 (Pak1)  Endocytosis   Macropinocytosis    Kinases     29431 (Pak1) Chromosome and associated proteins [BR:rno03036]  Eukaryotic type   Sister chromatid separation proteins    Aurora kinases     Regulators of Aurora kinases      29431 (Pak1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal DSHCT APH Kdo Motif Other DBs NCBI-GeneID:  29431 NCBI-ProteinID:  NP_058894 RGD:  3250 Ensembl:  ENSRNOG00000029784 UniProt:  P35465 Structure PDB LinkDB All DBs Position 1:152111172..152226390 Genome browser AA seq 544 aa AA seqDB search MSNNGLDVQDKPPAPPMRNTSTMIGAGSKDPGTLNHGSKPLPPNPEEKKKKDRFYRSILA GDKTNKKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGMPEQWARLLQTSNITKSEQKKN PQAVLDVLEFYNSKKTSNSQKYMSFTDKSAEDYNSSNTLNVKTVSETPAVPPVSEDEDDD DDATPPPVIAPRPEHTKSVYTRSVIEPLPVTPTRDVATSPISPTENNTTPPDALTRNTEK QKKKPKMSDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTAMDVATGQEVAIKQM NLQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCM DEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKR STMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGT PELQNPEKLSAIFRDFLNRCLEMDVEKRGSAKELLQHQFLKIAKPLSSLTPLIAAAKEAT KNNH NT seq 1635 nt NT seq  +upstreamnt  +downstreamnt atgtcaaataacggcttagacgtccaggacaaacccccagcccctccgatgagaaacacc agcactatgattggagctggcagcaaagaccctggaaccctaaaccacggttccaaacct ctgcctccaaacccagaggagaagaaaaagaaggaccggttctatcgatccatcttagct ggagataaaacaaataaaaagaaggagaaggagcggccagagatttctcttccttcagat tttgagcatacaattcatgttggttttgatgctgtcacaggggagtttacggggatgcca gaacagtgggcccgcttgcttcaaacatcaaatatcaccaagtcagagcagaagaaaaac ccacaggctgttctggatgtgttggaattttataactccaagaagacctccaatagtcag aagtacatgagttttacagataagtcagctgaagattataattcttctaatactttgaat gtgaagactgtgtctgagaccccagcagtgccaccagtgtcagaagatgaagatgatgat gacgatgctaccccacctccagtgattgctccacgcccagaacacacaaaatctgtatat acacggtctgtgattgaaccacttcctgttactccaactcgggatgtggctacatctcct atttctcctactgagaataacaccactccgccagatgctttgacccggaatactgaaaag cagaagaagaagcctaaaatgtctgatgaggagatcttagagaaattacggagcatagtg agtgtgggcgatcctaagaagaagtacacacgcttcgagaagattggacaaggtgcttca ggcacagtgtacactgcaatggatgtagccacagggcaggaggtggccattaaacagatg aaccttcagcagcagccgaagaaagaactcattattaatgagatcctggtcatgagggaa aacaaaaacccaaacattgtgaactatctggacagttaccttgtgggagatgagctatgg gttgtcatggaatacttggccggaggctccttaacagatgtggtgacagaaacctgtatg gatgaaggccagatagcagctgtgtgccgagagtgtctacaagctttggagttcctgcat tcaaaccaagtcattcacagagacatcaagagtgacaatattctgctgggaatggatggc tctgtcaaattaactgactttggattctgtgcacagataactccagagcagagcaaaagg agcaccatggtgggaactccatattggatggcacctgaagttgtgacacgcaaggcctat ggacccaaggttgacatctggtccctgggtattatggcaattgaaatgattgagggggag cccccatacctcaatgaaaaccctttgagagccttgtacctcattgctaccaatgggacg ccagagcttcagaacccagagaagttgtcagctattttccgggactttttgaaccgctgt cttgagatggatgtggagaagagaggttcagctaaagagctactgcagcatcaattcctg aagattgccaagcctctctccagcctgactccactgattgctgcagcaaaagaggcaacc aagaacaatcactga

Rattus norvegicus (rat): 29432 Help Entry 29432             CDS       T01003                                  Symbol Pak2 Name (RefSeq) serine/threonine-protein kinase PAK 2   KO K04410   p21-activated kinase 2 [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno04010   MAPK signaling pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04360   Axon guidance rno04510   Focal adhesion rno04660   T cell receptor signaling pathway rno04810   Regulation of actin cytoskeleton rno05170   Human immunodeficiency virus 1 infection rno05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     29432 (Pak2)    04012 ErbB signaling pathway     29432 (Pak2)    04014 Ras signaling pathway     29432 (Pak2)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     29432 (Pak2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     29432 (Pak2)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     29432 (Pak2)   09158 Development and regeneration    04360 Axon guidance     29432 (Pak2)  09160 Human Diseases   09162 Cancer: specific types    05211 Renal cell carcinoma     29432 (Pak2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     29432 (Pak2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     29432 (Pak2) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      29432 (Pak2) Protein kinases [BR:rno01001]  Serine/threonine kinases: STE group   STE20 family    29432 (Pak2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD Kinase-like Pkinase_fungal ABC1 APH Kdo zinc-ribbons_6 Motif Other DBs NCBI-GeneID:  29432 NCBI-ProteinID:  NP_445758 RGD:  61953 Ensembl:  ENSRNOG00000048597 UniProt:  Q64303 Structure PDB LinkDB All DBs Position 11:68708070..68766622 Genome browser AA seq 524 aa AA seqDB search MSDNGELEDKPPAPPVRMSSTIFSTGGKDPLSANHSLKPLPSVPEEKKPRNKIISIFSST EKGSKKKEKERPEISPPSDFEYTIHVGFDAVTGEFTGMPEQWARLLQTSNITKLEQKKNP QAVLDVLKFYDSNTVKQKYLSFTPPEKDGFPSGTPALNTKGSETSAVVTEEDDDDEDAAP PVIAPRPDHTKSIYTRSVIDPIPAPVGDSNVDSGAKSSDKQKKKAKMTDEEIMEKLRTIV SIGDPKKKYTRYEKIGQGASGTVFTATDVALGQEVAIKQINLQKQPKKELIINEILVMKE LKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQIAAVCRECLQALEFLH ANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTREAY GPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTPELQNPEKLSPIFRDFLNRC LEMDVEKRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAMKSNR NT seq 1575 nt NT seq  +upstreamnt  +downstreamnt atgtctgataacggggagctagaggacaagcccccagcacctccagtgcggatgagcagc accatttttagcactggaggaaaggatcctttatcagccaatcacagtttgaagcctttg ccttctgttccagaggaaaaaaaaccgaggaacaaaatcatctccatattctcaagcaca gaaaaaggaagtaaaaagaaagaaaaagaacggccagagatttctccgccgtctgatttt gagtataccatccatgttggctttgatgctgttacgggagagttcactggcatgccagag cagtgggcacggctgttgcagacctccaacattaccaaactggagcagaagaagaacccg caggctgtgctggatgtcttgaagttctacgactccaacactgtgaagcagaagtacctg agcttcactcctcctgagaaagatggctttccttctggaacaccagcactgaacaccaag gggtcagagacatcagctgtggtgacagaggaagacgatgacgatgaagatgctgctcct cccgtcattgcccctcggccagatcatacaaaatcaatctacacaaggtctgtcatcgac cctattcctgctccagttggtgactctaatgtcgacagtggtgccaagtcttcagacaaa cagaaaaagaaagccaagatgaccgatgaagagattatggagaaattaagaactattgtg agcataggtgaccctaagaaaaaatacacaagatatgaaaaaatcgggcaaggggcttct ggtacagtttttactgcaactgatgtggccctggggcaagaggttgctatcaagcagatt aatttacagaaacaaccaaagaaggaattgatcattaatgaaattctggtgatgaaggag ttaaagaatcccaacatagttaacttcttggacagttacctggtaggagacgagttgttt gtggtaatggagtaccttgctggtgggtccctcactgatgtcgtgacagaaacctgcatg gatgaagcgcagatcgcagctgtgtgcagagagtgtttacaggcgttggagtttttacat gctaatcaagtgatccacagagacatcaaaagtgacaatgtgcttttgggaatggaaggc tcagttaaactcactgattttggcttctgtgcccagatcacccctgaacagagcaaacgc agtacaatggttggaacgccatactggatggcaccggaggtagtcacgcgggaagcctat ggccccaaagttgacatatggtctctgggcatcatggctatcgaaatggtggaaggagag cctccatacctcaatgaaaatcctttacgggcattatacctgatagcaacgaatggaaca cctgagctccagaatccagaaaaactttcccccatatttcgggatttcttaaatcggtgt ttggaaatggatgtggagaagaggggttcagccaaagaactattacagcatcctttcctg aaactggccaaaccattatccagcttgacgcctctgatcctggcagctaaagaagcaatg aagagtaaccgctaa

Rattus norvegicus (rat): 29433 Help Entry 29433             CDS       T01003                                  Symbol Pak3 Name (RefSeq) serine/threonine-protein kinase PAK 3   KO K05733   p21-activated kinase 3 [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04360   Axon guidance rno04510   Focal adhesion rno04660   T cell receptor signaling pathway rno04810   Regulation of actin cytoskeleton rno05132   Salmonella infection rno05170   Human immunodeficiency virus 1 infection rno05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     29433 (Pak3)    04014 Ras signaling pathway     29433 (Pak3)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     29433 (Pak3)   09142 Cell motility    04810 Regulation of actin cytoskeleton     29433 (Pak3)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     29433 (Pak3)   09158 Development and regeneration    04360 Axon guidance     29433 (Pak3)  09160 Human Diseases   09162 Cancer: specific types    05211 Renal cell carcinoma     29433 (Pak3)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     29433 (Pak3)   09171 Infectious disease: bacterial    05132 Salmonella infection     29433 (Pak3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     29433 (Pak3) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      29433 (Pak3) Protein kinases [BR:rno01001]  Serine/threonine kinases: STE group   STE20 family    29433 (Pak3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD Pkinase_fungal ABC1 Kinase-like Spt5_N DSHCT APH Kdo Motif Other DBs NCBI-GeneID:  29433 NCBI-ProteinID:  NP_062083 RGD:  3251 Ensembl:  ENSRNOG00000004676 UniProt:  Q62829 LinkDB All DBs Position X:107116308..107374342 Genome browser AA seq 544 aa AA seqDB search MSDSLDNEEKPPAPPLRMNSNNRDSSALNHSSKPLPMAPEEKNKKARLRSIFPGGGDKTN KKKEKERPEISLPSDFEHTIHVGFDAVTGEFTGIPEQWARLLQTSNITKLEQKKNPQAVL DVLKFYDSKETVNNQKYMSFTSGDKSAHGYIAAHQSNTKTASEPPLAPPVSEEEDEEEEE EEDDNEPPPVIAPRPEHTKSIYTRSVVESIASPAAPNKEATPPSAENANSSTLYRNTDRQ RKKSKMTDEEILEKLRSIVSVGDPKKKYTRFEKIGQGASGTVYTALDIATGQEVAIKQMN LQQQPKKELIINEILVMRENKNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMD EGQIAAVCRECLQALDFLHSNQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRS TMVGTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEPPYLNENPLRALYLIATNGTP ELQNPERLSAVFRDFLNRCLEMDVDRRGSAKELLQHPFLKLAKPLSSLTPLILAAKEAIK NSSR NT seq 1635 nt NT seq  +upstreamnt  +downstreamnt atgtctgacagcttggataacgaagaaaaacctccagctcccccactgaggatgaacagt aacaaccgagattcttcagcactcaaccacagctccaaaccactgcccatggccccggaa gagaagaataagaaagccaggcttcgctctatcttcccaggaggaggggataaaaccaat aagaagaaagagaaagaacgcccagagatctctcttccttcagactttgagcatacgatt catgtgggttttgatgcagtcaccggggaattcactggaattcctgaacaatgggctcga ctgctccaaacctccaacattacaaaactggaacagaagaagaacccacaggctgttctg gatgttctcaagttttacgactccaaagaaacagtcaacaaccagaaatacatgagcttt acatcaggagataaaagtgcccatggatatatagcagcacatcagtcgaataccaaaaca gcttcagaacctcctttggctcctcctgtatctgaagaagaggatgaagaagaggaagag gaagaagatgataatgagcccccgcctgtcattgcaccaagaccagagcatacaaaatca atctatactcgttctgtggttgagtcaattgcttcaccagcagcaccaaataaagaagcc accccaccttctgctgagaatgccaattccagtactttgtacaggaatacagatcggcaa agaaaaaaatccaagatgacagatgaggagatcctagagaagctaagaagcattgtgagt gttggggacccaaagaagaaatatacaagatttgaaaaaattggccaaggggcatcagga actgtttacacagcactagacattgcgacaggacaagaggtggctataaagcaaatgaac cttcaacagcagcccaaaaaggaattaattattaatgaaattcttgtcatgagggaaaat aagaaccccaatattgtcaattatttagatagctacttagtgggtgatgaactgtgggta gtcatggaatacttggctggtggctctttgactgacgtggtcacagaaacctgtatggat gaaggacagatagcagccgtctgtagagagtgcctccaagctttggatttcttgcactca aaccaagtgatccacagagatataaagagtgacaatattctcctcgggatggatggttct gttaaactgactgattttggattctgtgcccaaatcactcctgagcaaagtaaacgaagc actatggtgggaactccctattggatggcacctgaggtggtaactcgaaaagcttatggc ccgaaagttgatatctggtctctgggaatcatggccattgaaatggtggaaggtgaaccc ccttaccttaatgaaaatccactcagggccttatatctgatagccactaatggaacccca gagctccagaatcccgagagactgtcagctgtattccgtgacttcttaaatcgctgtctt gagatggatgtggatagacgagggtctgccaaggagcttttgcagcatccatttttaaaa ttagccaagcccctgtccagcctcactcctctgattcttgctgcaaaggaagccattaag aacagtagccgttag

Rattus norvegicus (rat): 296078 Help Entry 296078            CDS       T01003                                  Symbol Pak6 Name (RefSeq) serine/threonine-protein kinase PAK 6   KO K05735   p21-activated kinase 6 [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04360   Axon guidance rno04510   Focal adhesion rno04660   T cell receptor signaling pathway rno04810   Regulation of actin cytoskeleton rno05170   Human immunodeficiency virus 1 infection rno05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     296078 (Pak6)    04014 Ras signaling pathway     296078 (Pak6)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     296078 (Pak6)   09142 Cell motility    04810 Regulation of actin cytoskeleton     296078 (Pak6)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     296078 (Pak6)   09158 Development and regeneration    04360 Axon guidance     296078 (Pak6)  09160 Human Diseases   09162 Cancer: specific types    05211 Renal cell carcinoma     296078 (Pak6)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     296078 (Pak6)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     296078 (Pak6) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      296078 (Pak6) Protein kinases [BR:rno01001]  Serine/threonine kinases: STE group   STE20 family    296078 (Pak6) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD Kinase-like ABC1 Pkinase_fungal Kdo Motif Other DBs NCBI-GeneID:  296078 NCBI-ProteinID:  NP_001099968 RGD:  1306213 Ensembl:  ENSRNOG00000007925 UniProt:  D3ZQ51 LinkDB All DBs Position 3:105638248..105674399 Genome browser AA seq 681 aa AA seqDB search MFRKKKKKRPEISAPQNFQHRVHTSFDPKEGKFVGLPPQWQNILDTLRRPKPVVDPSRIT RVQLQPMKTVVRGSSVPTEGYISGLLNDIQKLSAISSNTLRGRSPTSRRRAQSLGLLGDD QWAADPDMYLQSPQSERTDPHGVYLSCNGGTPAGHRQTPWPEPQSPQALPNGMAAKAQSL GPAEFQGASQRCLQLGACLQSSPPGTSPPMATGRRGVKVTKHSSEEARPQSCLVGSAIGR PGGEGSPSPKTQESSLKHRLFRSMFLSTPATGSASSSKPVPLPQNKLNSAFRPPQKDSSS NLVAKAQSLPSDQPTGTFSPLTTSDTSSPQKSLRTAPATGPLPGRSSPAGSPRTRHAQIS TSNLYLPQDPTVAKGALGGEDTGIVTHEQFKAALRMVVDQGDPRLLLDSYVKIGEGSTGI VCLAREKHSGRQVAVKMMDLRKQQRRELLFNEVVIMRDYQHLNVVEMYKSYLVGEELWVL MEFLQGGALTDIISQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILLTLDGRV KLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEMVDGEPP YFSDSPVQAMKRLRDSPPPKLKNSYKVSPVLRDFLERMLVREPQERATAQELLDHPFLLQ TGLPECLVPLIQLYRKQTSTC NT seq 2046 nt NT seq  +upstreamnt  +downstreamnt atgttccgaaagaagaagaagaaacgccctgagatatcagccccacagaacttccagcac cgtgttcacacctcatttgaccccaaggaaggcaagttcgtgggcctgcccccacaatgg cagaacatcctggatactctgaggcggcccaagcctgtggtggatccttctcgaatcaca cgggtgcagttgcagcccatgaagacggtagtacggggcagctcagtgcccacagagggc tacatctccgggctgctcaatgacattcagaagttgtcagctatcagctccaacactctg cgtggacgcagccccaccagccggcggcgggcacagtccctggggctgctaggagatgat cagtgggcggctgacccggatatgtacctccaaagtcctcagtctgagcgcactgatccc catggcgtctacctcagctgtaatgggggcacaccagcaggtcacaggcaaacgccatgg ccagaaccacagagcccacaggccctgcccaatggcatggctgccaaggcacagtcgctg ggccccgctgagttccagggtgcctcccaacgctgcctgcagctgggtgcctgcctacag agttccccacctggtacctcaccccctatggccacagggaggcgtggggtgaaggttacc aagcatagctcggaagaggctcgaccacaatcttgcctggtgggctcagccattggcaga ccaggtggagaaggcagccccagccctaagacccaggaaagcagcctcaagcaccggctc ttccgcagcatgttcctgtccactcccgccacaggctctgcaagcagcagcaagccggtc cctctgccacagaacaagctcaattctgctttccgaccaccacaaaaagattcctcttca aacctggtagccaaggcccagtccttgccctcagatcagcccacggggaccttcagtcct ctgaccacctcagataccagcagtccccagaagtccctccgcacagccccagccactggt ccacttccaggccggtcttctccagcaggctccccccgcacccggcatgcccagatcagc accagcaatctatacctgccccaggaccccacagtggccaagggggccctgggtggcgaa gacacaggcatcgtaacacatgagcagttcaaagctgcgctcaggatggtggtggaccag ggtgaccctcggctgctgctggacagctatgtgaagattggggagggctccacgggcatt gtgtgtctggcccgggagaagcattcaggtcgccaggtagcagtcaagatgatggacctc agaaagcagcaacgcagggaactgctctttaatgaggtggtgatcatgcgtgactaccag cacctcaatgtggtggagatgtacaagagttacctggtaggagaggagctgtgggtgctg atggagttcctgcagggcggggccctcacagacatcatctcccaagtcagactcaatgag gaacagattgctactgtgtgtgaagctgtgcttcaggccttggcttacctgcacgcccag ggtgtcatccaccgagacatcaagagtgattccatcctgctgacccttgatggcagggtg aagctctcagactttgggttctgtgctcagatcagcaaagatgtccccaagagaaagtct ctcgtaggaactccatactggatggctcctgaggtgatctccagatccctgtacgctact gaggtggatatctggtctctgggcatcatggtgattgagatggtggatggagaaccccct tacttcagcgactccccagtgcaagccatgaagaggctccgggacagccccccacccaag ctaaagaactcttacaaggtctctccagtgctgcgagacttcctggaacgaatgctggta cgggaaccccaagagagagccacagcccaggagctcctggatcacccctttctgctgcag acggggctgcccgagtgtctggtgcctctgatacagctctaccgcaagcagacctccacc tgctga

Rattus norvegicus (rat): 311450 Help Entry 311450            CDS       T01003                                  Symbol Pak5 Name (RefSeq) serine/threonine-protein kinase PAK 5   KO K05736   p21-activated kinase 5 [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno04012   ErbB signaling pathway rno04014   Ras signaling pathway rno04360   Axon guidance rno04510   Focal adhesion rno04660   T cell receptor signaling pathway rno04810   Regulation of actin cytoskeleton rno05170   Human immunodeficiency virus 1 infection rno05211   Renal cell carcinoma Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     311450 (Pak5)    04014 Ras signaling pathway     311450 (Pak5)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04510 Focal adhesion     311450 (Pak5)   09142 Cell motility    04810 Regulation of actin cytoskeleton     311450 (Pak5)  09150 Organismal Systems   09151 Immune system    04660 T cell receptor signaling pathway     311450 (Pak5)   09158 Development and regeneration    04360 Axon guidance     311450 (Pak5)  09160 Human Diseases   09162 Cancer: specific types    05211 Renal cell carcinoma     311450 (Pak5)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     311450 (Pak5)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     311450 (Pak5) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      311450 (Pak5) Protein kinases [BR:rno01001]  Serine/threonine kinases: STE group   STE20 family    311450 (Pak5) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr PBD ABC1 Kinase-like Pkinase_fungal Motif Other DBs NCBI-GeneID:  311450 NCBI-ProteinID:  NP_001101251 RGD:  1312009 Ensembl:  ENSRNOG00000005509 UniProt:  D4A280 LinkDB All DBs Position 3:complement(123395678..123703967) Genome browser AA seq 718 aa AA seqDB search MFGKKKKKIEISGPSNFEHRVHTGFDPQEQKFTGLPQQWHSLLADTANRPKPMVDPSCIT PIQLAPMKTIVRGNKSCKESSINGLLEDFDNISVTRSNSLRKESPPTPDQGAASRIQGHS EENGFITFSQYSSESDTTTDYTTEKYRDRSLYGDDLDLYYRGSHAAKQNGHAMKMKHGDA YYPEMKPLKSDLARFPVDYHTHLDSLSKASEYGDLKWDYQRASSSSPLDYSFQLTPSRTA GTSRCSKESLAYSESDWGPSFDDYDRRPKSSYLHQTSPQPAMRQRSKSGSGLQEPMMPFG ASAFKTHPQGHSYNSYTYPRLSEPTMCIPKVDYDRAQMVFSPPLSGSDTYPRGPTKLPQS QSKVGYSSSSHQYPGYHKASLYHHPSLQTSSQYISTASYLSSLSISSSTYPPPSWGSSSD QQPSRVSHEQFRAALQLVVSPGDPREYLDNFIKIGEGSTGIVCIATEKHTGKQVAVKKMD LRKQQRRELLFNEVVIMRDYHHDNVVDMYNSYLVGDELWVVMEFLEGGALTDIVTHTRMN EEQIATVCLSVLKALSYLHNQGVIHRDIKSDSILLTSDGRIKLSDFGFCAQVSKEVPKRK SLVGTPYWMAPEVISRLPYGTEVDIWSLGIMVIEMIDGEPPYFNEPPLQAMRRIRDSLPP RVKDLHKVSSMLRGFLDLMLVREPSQRATAQELLGHPFLKLAGPPSCIVPLMRQYRHH NT seq 2157 nt NT seq  +upstreamnt  +downstreamnt atgtttgggaagaaaaagaaaaagatcgaaatatccggcccatctaactttgaacacagg gttcatactgggtttgatccacaagagcagaagtttactggccttccccagcagtggcac agcctgttagcagacacagccaacaggcccaagcctatggtggatccatcatgcatcaca cccatacaactggctcccatgaagacaatcgtcagaggaaataaatcctgcaaggaaagc tctatcaacggtctgctagaggatttcgacaacatctccgtgactcgctccaactcccta aggaaagaaagcccacccaccccagatcagggagcagctagccgcattcaaggccactcc gaagaaaacggcttcattactttctcacaatattctagtgaatctgatactactacggac tacacaactgaaaagtatagagacaggagtctctatggagacgacctggatctgtactat agaggcagccatgcagccaagcaaaacgggcatgctatgaagatgaaacatggagatgcc tactatcctgagatgaagcctttgaaatccgacctggccagattccctgtcgactatcac acacacttggactcgctgagcaaagcaagtgagtacggtgacctcaagtgggattatcag cgagcctccagtagctcccctctggactactcattccagctcacgccttccagaactgca gggaccagcaggtgctccaaggagagtctggcatacagtgaaagtgattggggacccagc tttgatgactatgataggaggccaaaatcatcctacctgcatcagacaagccctcagcca gccatgcgccagagatccaagtcaggctcagggcttcaggaacccatgatgccatttgga gcaagtgcatttaaaactcatcctcaaggacactcgtacaactcctacacctaccctcga ttgtctgagcccacaatgtgcattccaaaggtggattatgatcgagcacagatggtcttc agtcctccactgtcagggtccgacacctatcccagaggccccaccaaactacctcaaagt caaagcaaagtgggctactcttcaagtagccaccagtatcctgggtaccacaaagcatcc ctataccatcatccgtccctgcaaaccagttctcagtacatctccaccgcttcttacttg agctctctcagtatctcctcgagcacctaccctccacccagctggggctcctcttcagac cagcagccctctagggtatcccatgaacagtttcgagctgccctgcaactggtggtcagc ccaggagaccccagggaatatttggataactttattaaaatcggagaagggtcgacaggc atcgtgtgcattgcaacagagaagcacacaggcaagcaagtggcggtgaagaaaatggac ctccgaaagcaacagagacgggaactcctttttaatgaggtcgtgataatgcgtgattac caccatgacaatgtagttgacatgtataacagctaccttgttggagatgagctctgggtg gtcatggagtttctagaaggtggtgccttgacagacatcgtcactcataccagaatgaat gaagaacagatagctactgtctgcctgtcagttctgaaagcgctgtcctaccttcataac caaggagtgattcacagggacataaagagtgactccattcttctgacaagcgatggccgg ataaagttatctgactttggcttctgtgctcaagtttccaaagaggtgccaaagaggaag tcactggtgggtaccccatactggatggctcctgaggtgatttccaggctaccttatggg acagaggtggacatctggtccctcgggataatggtgatagagatgattgatggtgagcct ccctatttcaatgagcctcctctgcaggccatgaggaggatccgggacagtttacctcca agagtgaaggacctgcacaaggtttcttccatgctccgaggattcctagatcttatgttg gtgagggagccctctcaaagagccacagctcaagaacttcttggacatccattcttaaaa ttggcaggcccgccatcttgcatcgttcccctcatgagacaatataggcatcactga

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