Rattus norvegicus (rat): 361696 Help Entry 361696            CDS       T01003                                  Symbol Rps6kb2 Name (RefSeq) ribosomal protein S6 kinase beta-2   KO K04688   ribosomal protein S6 kinase beta [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno01522   Endocrine resistance rno04012   ErbB signaling pathway rno04066   HIF-1 signaling pathway rno04140   Autophagy - animal rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04152   AMPK signaling pathway rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04350   TGF-beta signaling pathway rno04371   Apelin signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno04714   Thermogenesis rno04910   Insulin signaling pathway rno04931   Insulin resistance rno05163   Human cytomegalovirus infection rno05165   Human papillomavirus infection rno05170   Human immunodeficiency virus 1 infection rno05200   Pathways in cancer rno05205   Proteoglycans in cancer rno05207   Chemical carcinogenesis - receptor activation rno05210   Colorectal cancer rno05212   Pancreatic cancer rno05221   Acute myeloid leukemia rno05224   Breast cancer rno05225   Hepatocellular carcinoma rno05226   Gastric cancer rno05231   Choline metabolism in cancer rno05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     361696 (Rps6kb2)    04350 TGF-beta signaling pathway     361696 (Rps6kb2)    04371 Apelin signaling pathway     361696 (Rps6kb2)    04066 HIF-1 signaling pathway     361696 (Rps6kb2)    04151 PI3K-Akt signaling pathway     361696 (Rps6kb2)    04152 AMPK signaling pathway     361696 (Rps6kb2)    04150 mTOR signaling pathway     361696 (Rps6kb2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     361696 (Rps6kb2)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     361696 (Rps6kb2)   09152 Endocrine system    04910 Insulin signaling pathway     361696 (Rps6kb2)   09149 Aging    04211 Longevity regulating pathway     361696 (Rps6kb2)    04213 Longevity regulating pathway - multiple species     361696 (Rps6kb2)   09159 Environmental adaptation    04714 Thermogenesis     361696 (Rps6kb2)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     361696 (Rps6kb2)    05205 Proteoglycans in cancer     361696 (Rps6kb2)    05207 Chemical carcinogenesis - receptor activation     361696 (Rps6kb2)    05231 Choline metabolism in cancer     361696 (Rps6kb2)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     361696 (Rps6kb2)   09162 Cancer: specific types    05210 Colorectal cancer     361696 (Rps6kb2)    05212 Pancreatic cancer     361696 (Rps6kb2)    05225 Hepatocellular carcinoma     361696 (Rps6kb2)    05226 Gastric cancer     361696 (Rps6kb2)    05221 Acute myeloid leukemia     361696 (Rps6kb2)    05224 Breast cancer     361696 (Rps6kb2)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     361696 (Rps6kb2)    05163 Human cytomegalovirus infection     361696 (Rps6kb2)    05165 Human papillomavirus infection     361696 (Rps6kb2)   09167 Endocrine and metabolic disease    04931 Insulin resistance     361696 (Rps6kb2)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     361696 (Rps6kb2)    01522 Endocrine resistance     361696 (Rps6kb2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     361696 (Rps6kb2) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      361696 (Rps6kb2) Protein kinases [BR:rno01001]  Serine/threonine kinases: AGC group   RSK family [OT]    361696 (Rps6kb2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 Seadorna_VP7 DUF6499 Motif Other DBs NCBI-GeneID:  361696 NCBI-ProteinID:  NP_001010962 RGD:  1305144 Ensembl:  ENSRNOG00000021689 UniProt:  A6HYU9 LinkDB All DBs Position 1:complement(201451265..201458096) Genome browser AA seq 485 aa AA seqDB search MAAVFDLDLETEEGSEGEGEPEFNPADVCPLGELRAAGLETVGHYEEVELTESSVNLGPE RIGPHCFELLSVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVCSAKDTAHTRAER NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL ALGHLHSQGIIYRDLKPENIMLNSQGHIKLTDFGLCKESIHEGAITHTFCGTIEYMAPEI LVRIGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLVLPPYLTPDARDLA KKFLKRNPTHRIGGGPGDAADVQRHPFFRHINWDDLLAHRVDPPFRPSLQSEEDVSQFDV RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRT PISPLKFSPFEGFRPSPGPPEPMEPSLPPLLPPPSSPPPTSTAPLPIRPPSGTKKSKKGR GRPGR NT seq 1458 nt NT seq  +upstreamnt  +downstreamnt atggcggccgtgtttgatttagacttggagaccgaggaaggaagtgagggcgagggcgag ccggagttcaaccctgcggacgtgtgtccccttggcgagttaagggctgctggcctggag acagtgggacactatgaggaggtggaactgacagagagcagcgtcaacctgggtcctgag cgcatcggaccccactgctttgagctactgagtgttctgggcaaggggggttatggcaag gtgttccaggtgagaaaagtgcaaggcaccaacttgggcaaaatatatgccatgaaagtc ttgagaaaggccaagattgtatgcagtgccaaggacacagcacatacccgggctgagcgg aacattctagaatcggtgaagcaccccttcattgtagaactggcctatgctttccagaca ggtggcaaactctacctcatcctggagtgcctcagtggtggtgagctcttcacacatctt gagcgagaaggcatcttcctggaagacacagcctgcttctacctggcagagatcacacta gccctgggccatctccattcccaaggcatcatctaccgggatctcaagcccgagaacatc atgctcaacagccagggccatatcaaactgacagactttggactctgcaaagagtccatt catgagggtgctatcactcacaccttctgtggcaccattgagtacatggccccagagatt ctagtgcgcatcggtcacaaccgggcagtggactggtggagcctgggagccctgatgtac gacatgctcactggatcgccgcccttcaccgcagagaaccggaagaaaactatggataaa atcattaaagggaagctggtgctgcccccctacctcaccccggatgcccgggaccttgcc aaaaagtttctgaagcggaatcccactcatcgaattgggggtggcccaggagatgctgct gatgtgcagaggcacccgtttttccggcacatcaattgggatgacctcttggcccatcgt gtagaccctcccttcagaccgagtctgcaatcagaagaggacgtgagccagtttgatgtg cgattcacacggcagacgccagtagatagtccagatgacacagccctcagtgagagtgcc aaccaagccttcctgggcttcacgtatgtggcaccttctgtactggacagcatcaaagag ggcttctccttccagcctaagctgcgctcccccagacgccttaacagcagtccccgcacc cctatcagccccctcaagttctctccctttgaggggttccggcccagtcctggcccacca gagcccatggagccatctctacctccactcctgccaccaccatcatcaccaccacccaca agtactgccccacttcccatccgtcccccctcaggaaccaagaagtccaagaagggacgg ggccgccctgggcgctag

Rattus norvegicus (rat): 83840 Help Entry 83840             CDS       T01003                                  Symbol Rps6kb1 Name (RefSeq) ribosomal protein S6 kinase beta-1   KO K04688   ribosomal protein S6 kinase beta [EC:2.7.11.1] Organism rno  Rattus norvegicus (rat) Pathway rno01521   EGFR tyrosine kinase inhibitor resistance rno01522   Endocrine resistance rno04012   ErbB signaling pathway rno04066   HIF-1 signaling pathway rno04140   Autophagy - animal rno04150   mTOR signaling pathway rno04151   PI3K-Akt signaling pathway rno04152   AMPK signaling pathway rno04211   Longevity regulating pathway rno04213   Longevity regulating pathway - multiple species rno04350   TGF-beta signaling pathway rno04371   Apelin signaling pathway rno04666   Fc gamma R-mediated phagocytosis rno04714   Thermogenesis rno04910   Insulin signaling pathway rno04931   Insulin resistance rno05163   Human cytomegalovirus infection rno05165   Human papillomavirus infection rno05170   Human immunodeficiency virus 1 infection rno05200   Pathways in cancer rno05205   Proteoglycans in cancer rno05207   Chemical carcinogenesis - receptor activation rno05210   Colorectal cancer rno05212   Pancreatic cancer rno05221   Acute myeloid leukemia rno05224   Breast cancer rno05225   Hepatocellular carcinoma rno05226   Gastric cancer rno05231   Choline metabolism in cancer rno05235   PD-L1 expression and PD-1 checkpoint pathway in cancer Brite KEGG Orthology (KO) [BR:rno00001]  09130 Environmental Information Processing   09132 Signal transduction    04012 ErbB signaling pathway     83840 (Rps6kb1)    04350 TGF-beta signaling pathway     83840 (Rps6kb1)    04371 Apelin signaling pathway     83840 (Rps6kb1)    04066 HIF-1 signaling pathway     83840 (Rps6kb1)    04151 PI3K-Akt signaling pathway     83840 (Rps6kb1)    04152 AMPK signaling pathway     83840 (Rps6kb1)    04150 mTOR signaling pathway     83840 (Rps6kb1)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     83840 (Rps6kb1)  09150 Organismal Systems   09151 Immune system    04666 Fc gamma R-mediated phagocytosis     83840 (Rps6kb1)   09152 Endocrine system    04910 Insulin signaling pathway     83840 (Rps6kb1)   09149 Aging    04211 Longevity regulating pathway     83840 (Rps6kb1)    04213 Longevity regulating pathway - multiple species     83840 (Rps6kb1)   09159 Environmental adaptation    04714 Thermogenesis     83840 (Rps6kb1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     83840 (Rps6kb1)    05205 Proteoglycans in cancer     83840 (Rps6kb1)    05207 Chemical carcinogenesis - receptor activation     83840 (Rps6kb1)    05231 Choline metabolism in cancer     83840 (Rps6kb1)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     83840 (Rps6kb1)   09162 Cancer: specific types    05210 Colorectal cancer     83840 (Rps6kb1)    05212 Pancreatic cancer     83840 (Rps6kb1)    05225 Hepatocellular carcinoma     83840 (Rps6kb1)    05226 Gastric cancer     83840 (Rps6kb1)    05221 Acute myeloid leukemia     83840 (Rps6kb1)    05224 Breast cancer     83840 (Rps6kb1)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     83840 (Rps6kb1)    05163 Human cytomegalovirus infection     83840 (Rps6kb1)    05165 Human papillomavirus infection     83840 (Rps6kb1)   09167 Endocrine and metabolic disease    04931 Insulin resistance     83840 (Rps6kb1)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     83840 (Rps6kb1)    01522 Endocrine resistance     83840 (Rps6kb1)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:rno01001]     83840 (Rps6kb1) Enzymes [BR:rno01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.11  Protein-serine/threonine kinases     2.7.11.1  non-specific serine/threonine protein kinase      83840 (Rps6kb1) Protein kinases [BR:rno01001]  Serine/threonine kinases: AGC group   RSK family [OT]    83840 (Rps6kb1) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Pkinase PK_Tyr_Ser-Thr Pkinase_C Kinase-like Pkinase_fungal ABC1 APH Motif Other DBs NCBI-GeneID:  83840 NCBI-ProteinID:  NP_114191 RGD:  620683 Ensembl:  ENSRNOG00000003919 UniProt:  P67999 LinkDB All DBs Position 10:complement(71323777..71367908) Genome browser AA seq 525 aa AA seqDB search MRRRRRRDGFYPAPDFRHREAEDMAGVFDIDLDQPEDAGSEDELEEGGQLNESMDHGGVG PYELGMEHCEKFEISETSVNRGPEKIRPECFELLRVLGKGGYGKVFQVRKVTGANTGKIF AMKVLKKAMIVRNAKDTAHTKAERNILEEVKHPFIVDLIYAFQTGGKLYLILEYLSGGEL FMQLEREGIFMEDTACFYLAEISMALGHLHQKGIIYRDLKPENIMLNHQGHVKLTDFGLC KESIHDGTVTHTFCGTIEYMAPEILMRSGHNRAVDWWSLGALMYDMLTGAPPFTGENRKK TIDKILKCKLNLPPYLTQEARDLLKKLLKRNAASRLGAGPGDAGEVQAHPFFRHINWEEL LARKVERPFKPLLQSEEDVSQFDSKFTRQTPVDSPDDSTLSESANQVFLGFTYVAPSVLE SVKEKFSFEPKIRSPRRFIGSPRTPVSPVKFSPGDFWGRGASASTANPQTPVEYPMETSG IEQMDVTTSGEASAPLPIRQPNSGPYKKQAFPMISKRPEHLRMNL NT seq 1578 nt NT seq  +upstreamnt  +downstreamnt atgaggcgacgacggaggcgggacggcttttacccagcgcctgacttccgacacagggaa gctgaggacatggcaggagtgtttgacatagacctggaccagccagaggatgcaggctct gaggatgagctggaggaggggggtcagttaaatgaaagcatggaccatgggggagttgga ccatatgaacttggcatggaacattgtgagaaatttgaaatctcagaaactagtgtgaac agagggccagaaaaaatcagaccagaatgttttgagctacttcgggtacttggtaaaggg ggctatggaaaggtttttcaagtacgaaaagtaacaggagcaaatactgggaagatattt gccatgaaggtgcttaaaaaggcaatgatagtaagaaatgctaaagatacagctcataca aaagcagagcggaatattctggaggaagtaaagcatcccttcattgtggatttaatttat gcctttcagaccggtggaaaactctacctcatccttgagtatctcagtggaggagaacta tttatgcagttagaaagagaggggatattcatggaagatacagcttgcttttacttggct gaaatctccatggctttggggcatttacatcaaaaggggattatctacagagacctgaag ccggagaacatcatgcttaatcaccaaggtcacgtgaagctgacagactttggactatgc aaagaatctattcatgatggaacagtcacgcacacattttgtggaacaatagaatacatg gcccctgaaatcttgatgagaagcggccacaaccgtgctgtggattggtggagtctggga gcattaatgtatgacatgctgactggagcacctccattcactggggagaatagaaagaag acaattgacaaaatcctcaaatgtaaacttaatttgcctccctacctcacacaagaagct cgagatctgcttaaaaagctgctgaagagaaatgctgcttctcgtcttggagctggccct ggggatgctggagaagtccaagcgcatccattttttagacacattaactgggaagagctt ttggctcggaaggtggagcgcccctttaagcctctgttgcaatctgaagaggatgtgagt cagtttgattcaaagtttactcgtcagacacctgttgacagccccgatgactcaactctc agtgaaagtgccaaccaggtctttctgggttttacatatgtggctccatctgtacttgaa agtgtgaaagaaaagttttcttttgaaccaaaaatccgatcgcctcgaagatttattggt agcccacgaacgcctgtcagcccagtcaaattctctcctggggatttctggggacgaggt gcttcagccagcacagcaaatcctcagacacctgtggaatacccaatggaaacaagtgga atagagcagatggatgtgacaacgagcggggaagcttcagcgccacttccaatccgacag cccaactctgggccatacaaaaaacaagcttttcctatgatctccaaacggccagagcac ctgcgtatgaatctatga

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