Roseimicrobium sp. ORNL1: G5S37_07430
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Entry
G5S37_07430 CDS
T06460
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
roo
Roseimicrobium sp. ORNL1
Pathway
roo00300
Lysine biosynthesis
roo00550
Peptidoglycan biosynthesis
roo01100
Metabolic pathways
roo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
roo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
G5S37_07430
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
G5S37_07430
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
G5S37_07430
Enzymes [BR:
roo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
G5S37_07430
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QIF01358
UniProt:
A0A6G6K1N4
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Position
1847461..1848840
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AA seq
459 aa
AA seq
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MIPLTVQMVTEFCEGRLIKGDAQRICRSVSTDSRKLVAGQLFIALVGEKFDGHDFVNQAS
QAAATAVLVSKLPADTGSLSCAVIEVPDTLVALQKLAARHRQLLKPLVVGITGSNGKTST
KDLTLAVLRKKYEAMATAGNLNNHIGVPLTLLSMEEQHNCGVVEMGMNHPGEIAPLAEIA
RPDAAIITNIGIAHIEYMGSREAIALEKGTLAEAVHPGGVVVLNANDDFTPAIAARCKAR
VITAGVNAGEVRATIHESGAQGTRFTLDFGGTAQVQIQLAVPGEHMVGNAALAAACAWHH
GVSPDEIAAALGAASLTKGRLQVKSWRGVVFLDDSYNANPDSMKAGLKTLQTMQVKGRRV
AVLGRMGELGPHAEQGHREVGEFAARCGMGAVYTVGPEAALISNAFTASGGTGESRNFTS
HGECAEHLRAWLQEGDAVLLKGSRSTAMEQVLNHLETSP
NT seq
1380 nt
NT seq
+upstream
nt +downstream
nt
atgatcccgctcaccgtccagatggtgacggagttctgcgagggcaggctcatcaaaggt
gacgcacagcgcatctgccgcagtgtcagcacggactcacgcaagctcgtggcgggccag
cttttcatcgcactggtcggtgagaagttcgacgggcatgacttcgtgaaccaggcttcg
caagccgccgcgaccgctgtgctggtgagcaagcttcctgcggatacgggatcgctgagc
tgcgcagtcatcgaagtgccggacacacttgtggctctgcagaagctggccgcacgtcat
cgccagcttctcaagccactcgtcgtcggcatcaccggcagcaatgggaagacctccacc
aaggatctcacgctagccgtgctgcggaaaaagtatgaggccatggccacggcggggaac
ctgaacaaccacattggtgtgcccctcacgctgctgagcatggaggagcagcacaactgc
ggcgtggtggaaatgggcatgaaccatcccggggagatcgcgccgcttgcggagatcgcc
cggccggatgcggccatcatcacgaacatcggcatcgcccacattgagtacatgggttcg
cgtgaggccatcgccctggagaagggcacgctcgcggaagccgtgcaccccggtggtgtc
gtggtgttgaatgccaatgacgacttcacgccagccatcgccgcccgttgcaaggcgcgc
gtcatcaccgccggtgtgaatgccggtgaggtgcgcgccaccattcatgaaagcggcgcc
cagggcacacgcttcacgctcgattttggcgggacagcgcaggtccagattcagctcgct
gtaccaggcgagcacatggtgggaaatgcagccctggcagccgcatgcgcctggcatcat
ggtgtatcaccagatgagattgctgccgcgctcggagctgcctcactgaccaaaggccgc
ctgcaggtgaagtcctggcgcggcgtggtgttcctggatgattcctacaatgccaacccg
gactcgatgaaggccgggctgaagaccctgcagaccatgcaggtgaaggggcgccgcgtg
gctgtgctgggccggatgggcgaactcggtccgcatgccgagcagggccaccgggaggtg
ggcgagttcgccgcgcgctgcggcatgggcgcggtctacaccgtgggtccggaggccgct
ttaatctccaatgccttcaccgccagcggcggcacgggcgaaagcaggaacttcacctcg
catggcgagtgtgccgagcatctccgggcctggcttcaggaaggtgatgctgtcttgttg
aaagggagccgctccacggcgatggaacaggttctcaatcacctggaaacctccccatga
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